• International Journal of Naval Architecture and Ocean Engineering
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• v.13 no.1
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• pp.306-320
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• 2021

To ensure safe port operations around the world, it is important to solve mooring problems. In particular, the many ports that face open seas have difficulties with long-period waves. As a countermeasure, the installation of a breakwater is proposed for mooring safety. However, this often cannot be put into practice because of financial issues. Instead, port terminals control berthing schedules with weather forecasting. However, mooring problems remain unsolved, because of inaccurate wave forecasting. To quantify the current situation, numerical simulations are presented with ship motions, fender deflections, and rope tensions. In addition, novel simulations for mooring ropes are proposed considering tension, friction, bending fatigue, and temperature. With this novel simulation, the optimal mooring method in terms of safety and economic efficiency was confirmed. In terms of safety, the optimal mooring method is verified to minimize dangerous mooring situations. Moreover, the optimal mooring method shows economic benefits and efficiency. It can help to reinforce the safety of port terminals and improve the efficiency of port operations.

• Current Optics and Photonics
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• v.7 no.3
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• pp.263-272
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• 2023

A collimator refers to an optical system that images a collimated beam at a desired point. A resolution target located at a near distance can be converted into a virtual image located at a long distance. To test the resolution for mobile cameras, a large target is placed at a long distance. If a collimator system is used, the target can be placed at a near distance. The space required for a resolution inspection can thus be drastically reduced. However, to inspect a mobile camera, the exit pupil of the collimator system and the entrance pupil of the mobile camera must match, and the stop of the collimator system must be located on the last surface. Because a collimator system cannot be symmetrical with respect to the stop, the distortion becomes extremely large, which can be corrected by combining the collimator symmetrically with respect to the object plane. A novel system was designed to inspect an optical lens on a mobile phone. After arranging the refractive power, lenses were added using the equivalent lens design method. The distortion was reduced to less than 1%. This optical system satisfies a half-field angle of 45° and an optical performance sufficient for inspection.

• International Journal of Advanced Culture Technology
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• v.11 no.4
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• pp.393-405
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• 2023

Accurate prediction of wind speed and power is vital for enhancing the efficiency of wind energy systems. Numerous solutions have been implemented to date, demonstrating their potential to improve forecasting. Among these, deep learning is perceived as a revolutionary approach in the field. However, despite their effectiveness, the noise present in the collected data remains a significant challenge. This noise has the potential to diminish the performance of these algorithms, leading to inaccurate predictions. In response to this, this study explores a novel feature engineering approach. This approach involves altering the data input shape in both Convolutional Neural Network-Long Short-Term Memory (CNN-LSTM) and Autoregressive models for various forecasting horizons. The results reveal substantial enhancements in model resilience against noise resulting from step increases in data. The approach could achieve an impressive 83% accuracy in predicting unseen data up to the 24th steps. Furthermore, this method consistently provides high accuracy for short, mid, and long-term forecasts, outperforming the performance of individual models. These findings pave the way for further research on noise reduction strategies at different forecasting horizons through shape-wise feature engineering.

• Journal of Microbiology and Biotechnology
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• v.17 no.1
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• pp.15-20
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• 2007

To clone novel cry1-type genes from the Bacillus thuringiensis K1 isolate, about 2.4-kb-long PCR fragments were amplified with two primer sets of ATG1-F/N400-R and 1BeATG1-F/N400-R. Using PCR-RFLP, three novel cry1-type genes, cry1-1, cry1-7, and cry1-44, were obtained from B. thuringiensis K1 and the complete coding sequences of these novel genes were analyzed. The Cry1-1, Cry1-7, and Cry1-44 proteins showed maximum similarities of about 78.0%, 99.7%, and 91.0% with the Cry1Ha1, Cry1Be1, and Cry1Ac2 proteins, respectively. These novel cry1-type genes were expressed using a baculovirus expression vector system and their insecticidal activities were investigated. Whereas all three novel genes were toxic to Plutella xylostella larvae, only Cry1-1 showed insecticidal activity against Spodoptera exigua larvae.

• Acta Via Serica
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• v.8 no.2
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• pp.79-94
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• 2023

The purpose of this study is to examine the descriptions of the transmission of plague along the Silk Road in Orhan Pamuk's 2022 novel Nights of Plague. Pamuk won the Nobel Prize in Literature in 2006, the first prize for Turkish literature. Pamuk's vast knowledge of epidemiological history, which has long fascinated him, comes to life in this novel as he describes the characters' battles against the plague in the East and West and how the plague was brought to the islands and spread along the Maritime Silk Road. One of the most important trade routes in human history, the Silk Road was not only a link between East and West trade and cultures but also a route for the transmission of bubonic plague during the medieval period onwards. It was this epidemic that contributed to the decline of the Silk Road. In the novel, a plague originating in China strikes the Ottoman coastal cities of Smyrna and Mingheria on its way to Europe via India. The epidemic is contained in Smyrna but the death toll spirals out of control when the plague reaches the island of Mingheria by sea. The spatial setting of the novel is an island, which means that it communicates with the outside world by sea. The only way the plague could have spread to an isolated island was by ship. Rats from different ports and ships would have traveled to other parts of the world or even countries to spread the plague. In Nights of Plague, the fact that the plague reached Mingheria via the maritime Silk Road is also proven by the route of the ships and various narratives. The novel confirms what many scholars have argued, that the Silk Road brought various goods from the East to the Roman Empire, along with deadly diseases, and that the sea routes were an important way for the plague to travel and spread.

• Molecules and Cells
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• v.41 no.5
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• pp.486-494
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• 2018

Recently, we have reported that animals with telomerase reverse transcriptase (TERT) overexpression exhibit reduced social interaction, decreased preference for novel social interaction and poor nest-building behaviors-symptoms that mirror those observed in human autism spectrum disorders (ASD). Overexpression of TERT also alters the excitatory/inhibitory (E/I) ratio in the medial prefrontal cortex. However, the effects of TERT overexpression on hippocampal-dependent learning and synaptic efficacy have not been investigated. In the present study, we employed electrophysiological approaches in combination with behavioral analysis to examine hippocampal function of TERT transgenic (TERT-tg) mice and FVB controls. We found that TERT overexpression results in enhanced hippocampal excitation with no changes in inhibition and significantly impairs long-term synaptic plasticity. Interestingly, the expression levels of phosphorylated CREB and phosphorylated $CaMKII{\alpha}$ were significantly decreased while the expression level of $CaMKII{\alpha}$ was slightly increased in the hippocampus of TERT-overexpressing mice. Our observations highlight the importance of TERT in normal synaptic function and behavior and provide additional information on a novel animal model of ASD associated with TERT overexpression.

• Journal of the Korean Society for Precision Engineering
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• v.24 no.1 s.190
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• pp.64-70
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• 2007

A long-exposing technique (LET) has been conducted to create nanoscale patterns applicable to diverse micro-devices using two-photon polymerization (TPP). By the weakly-polymerized region via the LET, double-layered embossing patterns can be fabricated simply in a single step. The LET makes possible a voxel and its surrounding to be fully grown into more than 500 nm in lateral size and weakly-polymerized region (WPR), respectively. In the WPR. interconnecting ribs between voxels are generated, and they lead to the creation of double-layered dot patterns. Moreover, by controlling the distance between voxels, various shapes of interconnecting rib can be fabricated when the LET is applied. Various embossing patterns were fabricated to evaluate the usefulness of the proposed technique as a novel nanopatterning technique in TPP.

• Proceedings of the KIEE Conference
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• 2011.07a
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• pp.1228-1229
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• 2011

A novel approach has been promoted for FNN ship controllers. An Electro-hydraulic governor has been widely adopted to the ship speed control of propulsion marine diesel engines for a long time, it was very difficult for Electro-hydraulic governor to regulate the speed of high power engine with long stroke at low speed and low load, because of the jiggling phenomena by rough fluctuation of rotating torque and the hunting phenomena by long dead time occurred in fuel combustion process in the engine cylinder. This paper provides an efficient way for improving control performance by FNN controller. An RBF neural network and GA optimization are employed in a fuzzy neural controller to deal with the nonlinearity, time varying and uncertain factors, the rule base and membership functions can be auto-adjusted by GA optimization. The parameters of neural network can be decreased by using union-rule configuration in the hidden layer of the network. The performance of controller is evaluated by the system simulation using simulink tools.

• BMB Reports
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• v.45 no.11
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• pp.604-611
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• 2012

Recent advances in genome and transcriptome analysis have enabled identification of numerous members of a new class of noncoding RNA, long noncoding RNA (lncRNA). lncRNAs are broadly defined as RNA molecules greater than 200 nt in length and lacking an open reading frame. Recent studies provide evidence that lncRNAs play central roles in a wide range of cellular processes through interaction with key component proteins in the gene regulatory system, and that alteration of their cell- or tissue-specific expression and/or their primary or secondary structures is thought to promote cell proliferation, invasion and metastasis. The biological and molecular characteristics of the large majority of lncRNAs remains unknown, and it is anticipated that improved understanding of the roles played by lncRNAs in cancer will lead to the development of novel biomarkers and effective therapeutic strategies.

• Archives of Plastic Surgery
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• v.51 no.1
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• pp.126-129
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• 2024

The square flap method has been successful in releasing contracture bands at various body regions. However, the original square flap method alone may not be efficient in releasing long contracture bands. We, therefore, proposed an extended design to the traditional design, which is called the "square-plus flap." A 4-year-old girl presented with a postburn web-like contracture band over the right axilla. We marked a square flap technique at the center of the contracture band and then two additional Z-plasties were placed on both edges of the flap. After the release and securing of the square flap, the adjacent distal Z-plasty was then transposed and sutured in their new locations. We do not need to incise the proximal Z-plasty as we could achieve complete relaxation of the contracture band. This novel modification can be added to the plastic surgeon's armamentarium for releasing long postburn contracture bands involving distinct body regions.