• 조명전기설비학회논문지
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• 제16권2호
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• pp.98-103
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• 2002

전력수요를 예측할 경우 가장 중요한 문제 중의 하나가 특수일 부하의 처리문제이다. 따라서 본 연구에서 길고(구정, 추석) 짧은(식목일, 현충일 등) 특수일 피크 부하를 신경회로망과 회귀모형을 이용하여 예측하는 방법을 제시한다. 신경회로망 모형의 특수일 부하 처리는 패턴 변환비를 이용하며, 4차의 직교 다항 회귀모형은 과거의 10년 (1985∼1994)간의 특수일 피크부하 자료를 이용하여 길고 짧은 특수일 부하를 예측한다. 특수일 피크 부하를 예측한 결과, 신경회로망 모형의 주간 평균 예측 오차율과 직교 다항 회귀모형의 예측 오차율을 분석한 결과 1∼2[%]대로 두 모형 모두 양호한 결과를 얻었다. 또한 4차의 직교 다항 회귀 모형의 수정결정계수 및 F 검정을 분석한 결과 구성한 예측 모형의 타당성을 확인하였다. 두 모형의 특수일 부하를 예측한 결과를 비교해 보면 긴 특수일 부하를 예측할 때는 패턴 변환비를 이용한 신경회로망 모형이 보다 더 효과적이었고, 짧은 특수일 부하를 예측할 경우에는 두 방법 모두 유효하였다.

• 수산해양기술연구
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• 제37권3호
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• pp.159-162
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• 2001

낙지 주낙 어장의 환경요인이 어획량에 미치는 영향을 조사하기 위하여 1997년 1월부터 7월까지 여수연안에서 수온, 염분, 밀도, 풍향, 풍속등과 어획량을 각각 조사하고 이들을 서로 비교 분석한 결과를 요약하면 다음과 같다. 1) 풍향별 어획량은 남동풍일 때 가장 많았고 북서풍일 때 가장 적었으며, 풍속별 어획량은 2일 때 가장 많았고 그보다 커질 경우는 감소하였다. 2) 물때별 단위 노력당 어획량은 15물에서 가장 많고 4물에서 가장 적으며. 조류가 차차 약해지는 11∼14물 사이의 어획량이 조류가 차차 강해지는 1∼4물 사이의 어획량보다 많았다. 3) 썰물과 밀물 때의 어획량은 간조에서 만조로 바뀐 후 1시간 동안의 구간, 즉 간조에서 물이 들기 시작한지 1시간 동안에 어획량이 가장 많았고. 썰물 시각대 보다는 밀물 시각대에 어획량이 비교적 많은 경향이었다

• Journal of Korean Neurosurgical Society
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• 제52권6호
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• pp.517-522
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• 2012

Objective : Meningiomas represent 18-20% of all intracranial tumors and have a 20-50% 10-year recurrence rate, despite aggressive surgery and irradiation. Hydroxyurea, an inhibitor of ribonucleotide reductase, is known to inhibit meningioma cells by induction of apoptosis. We report the long-term follow-up result of hydroxyurea therapy in the patients with recurrent meningiomas. Methods : Thirteen patients with recurrent WHO grade I or II meningioma were treated with hydroxyurea (1000 $mg/m^2/day$ orally divided twice per day) from June 1998 to February 2012. Nine female and 4 male, ranging in age from 32 to 83 years (median age 61.7 years), were included. Follow-up assessment included physical examination, computed tomography, and magnetic resonance imaging (MRI). Standard neuro-oncological response criteria (Macdonald criteria) were used to evaluate the follow-up MRI scans. The treatment was continued until there was objective disease progression or onset of unmanageable toxicity. Results : Ten of the 13 patients (76.9%) showed stable disease after treatment, with time to progression ranging from 8 to 128 months (median 72.4 months; 6 patients still accruing time). However, there was no complete response or partial response in any patients. Three patients had progressive disease after 88, 89, 36 months, respectively. There was no severe (Grade III-IV) blood systemic disorders and no episodes of non-hematological side effects. Conclusion : This study showed that hydroxyurea is a modestly active agent against recurrent meningiomas and can induce long-term stabilization of disease in some patients. We think that hydroxyurea treatment is well tolerated and convenient, and could be considered as an alternative treatment option in patients with recurrent meningiomas prior to reoperation or radiotherapy.

• 수산해양기술연구
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• 제37권4호
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• pp.326-330
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• 2001

낙지주낙 어장의 환경요인이 어획량에 미치는 영향을 조사하기 위하여 1997년 1월부터 7월까지 여수연안에서 풍향, 풍속, 물때별 및 조업 시각대별로 어획량을 각각 사하고 이들을 서로 비교 분석한 결과를 요약하면 다음과 같다. 1) 풍향별 어획량은 남동풍일 때 가장 많았고 북서풍일 때 가장 적었으며, 풍속별 어획량은 2일 때 가장 많았고 그보다 커질 경우는 감소하였다. 2) 물때별 단위 노력당 어획량은 15물에서 가장 많고 4물에서 가장 적으며, 조류가 차차 약해지는 11∼14물 사이의 어획량이 조류가 차차 강해지는 1∼4물 사이의 어획량보다 많았다. 3) 썰물과 밀물 때의 어획량은 간조에서 만조로 바뀐 후 1시간 동안의 구간, 즉 간조에서 물이 들기 시작한지 1시간 동안에 어획량이 가장 많았고, 썰물 시각대 보다는 밀물 시각대에 어획량이 비교적 많은 경향이었다.

• 한국작물학회지
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• 제46권6호
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• pp.443-448
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• 2001

본 연구는 황기의 생식과 관련하여 자.웅배우체의 발육과정과 화분의 발아 특성을 밝혀서 품종 육성의 기초 자료로 활용하고자 수행한 바, 다음과 같은 결과를 얻었다. 1. 화분의 발육은 화뢰 길이가 3.5mm정도에서 화분모세포가 형성되어 4mm 정도 신장할 때까지 감수분열 및 동형분열하여 4분자기로 되었다. 2. 화뢰의 길이가 10mm정도 되면 성숙화분이 형성되고 12mm정도에서 개약하는 경향이었다. 3. 화분은 4$^{\circ}C$ 및 -4$^{\circ}C$ 저장시에는 저장후 30일 경에도 발아율이 양호 하였으나 상온(23~28$^{\circ}C$)에서는 저장후 3일부터는 발아력이 3%이하로 저하되었으며 발아속도도 저하되었다. 4.대포자의 형성시기는 소포자(화분)와 거의 비슷한 시기로 화뢰의 크기가 10~12mm에서 완전히 성숙하며, 꽃이 개화 되기전 화분의 미개약시에 자예는 수정 능력이 있는 것으로 나타났다.

• Journal of Korean Biological Nursing Science
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• 제21권3호
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• pp.217-223
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• 2019

Purpose: Caffeine is the most widely consumed psychostimulant of the methylxanthine class. Among adolescents, high-dose of caffeine consumption has increased rapidly over the last few decades due to the introduction of energy drinks. However, little is known about the time-dependent effect of high doses of caffeine consumption in adolescents. The present study aims to examine the short- and long-term influence of high-dose caffeine on behavior of adolescence. Methods: The animals were divided into three groups: a "vehicle" group, which was injected with 1 ml of phosphate-buffered saline for 14 days; a "Day 1" group, which was injected with caffeine (30 mg/kg), 2 h before the behavioral tests; and a "Day 14" group, which was infused with caffeine for 14 days. An open-field test, a Y-maze test, and a passive avoidance test were conducted to assess the rats'activity levels, anxiety, and cognitive function. Results: High-dose caffeine had similar effects in short-and long-term treatment groups. It increased the level of locomotor activity and anxiety-like behavior, as evidenced by the increase in the number of movements and incidences of rearing and grooming in the caffeine-treated groups. No significant differences were observed between the groups in the Y-maze test. However, in the passive avoidance test, the escape latency in the caffeine-treated group was decreased significantly, indicating impaired memory acquisition. Conclusion: These results indicate that high-dose caffeine in adolescents may increase locomotor activity and anxiety-like behavior and impair learning and memory, irrespective of the duration of administration. The findings will be valuable for both evidence-based education and clinical practice.

• Journal of Gastric Cancer
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• 제21권1호
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• pp.16-29
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• 2021

Purpose: Incidence, risk factors, and clinical consequences of pancreatic fistula (POPF) after D1+/D2 radical gastrectomy have not been well investigated in Western patients, particularly those from Eastern Europe. Materials and Methods: A total of 358 D1+/D2 radical gastrectomies were performed by surgeons with high caseloads in a single surgical center from 2002 to 2017. A retrospective analysis of data that were prospectively gathered in an electronic database was performed. POPF was defined and graded according to the International Study Group for Pancreatic Surgery (ISGPS) criteria. Uni- and multivariate analyses were performed to identify potential predictors of POPF. Additionally, the impact of POPF on early complications and long-term outcomes were investigated. Results: POPF was observed in 20 patients (5.6%), according to the updated ISGPS grading system. Cardiovascular comorbidities emerged as the single independent predictor of POPF formation (risk ratio, 3.051; 95% confidence interval, 1.161-8.019; P=0.024). POPF occurrence was associated with statistically significant increased rates of postoperative hemorrhage requiring re-laparotomy (P=0.029), anastomotic leak (P=0.002), 90-day mortality (P=0.036), and prolonged hospital stay (P<0.001). The long-term survival of patients with gastric adenocarcinoma was not affected by POPF (P=0.661). Conclusions: In this large series of Eastern European patients, the clinically relevant rate of POPF after D1+/D2 radical gastrectomy was low. The presence of co-existing cardiovascular disease favored the occurrence of POPF and was associated with an increased risk of postoperative bleeding, anastomotic leak, 90-day mortality, and prolonged hospital stay. POPF was not found to affect the long-term survival of patients with gastric adenocarcinoma.

• 한국식품영양학회지
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• 제34권6호
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• pp.621-630
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• 2021

In this study, we attempted to compare the maceration processes in the white wine made of Muscat of Alexandria grape having different the fermentation· maceration periods. These wine were sampled and analyzed by fermentation periods. The pH of wines ranged from 3.25 to 3.27 and the total acidity of wines ranged from 0.85~0.91% (w/v) on the 12th day of fermentation period. The ethanol concentration in these wines increased during the alcoholic fermentation period, on the other hand, the soluble solid concentrations (°Brix) decreased. The b value (yellowness) of Muscat of Alexandria wine was the highest at 8.31 in C treatment, which is a wine with a long maceration period, and B (7.19) and A (5.27) were significantly decreased as the maceration period was shorter. The total polyphenol and tannin content of wine increased with the period of maceration. Total polyphenol and tannin contents had the highest values (64.20 and 67.11 mg%, respectively) in the C treatment, which is a wine with a long maceration period on the 12th day of fermentation period. The physiological activities of Alexandria wine were highest level in the treatment with a long maceration period. As a result, this study provides useful scientific information that quality characteristics and physiological activities in white wine.

• 한국자원식물학회지
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• 제35권6호
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• pp.825-830
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• 2022

"Doha" is a new strawberry (Fragaria x ananassa Duch.) variety, which was released by the Highland Agriculture Research Institute in 2021. The "Doha" variety originates from a 2014 cross between "Saebong No. 3" and "Yeolha," both of which exhibited excellent ever-bearing characteristics, including continuous flowering and large fruits under long-day and high temperature conditions. This new cultivar was initially named "Saebong No. 13" after examining its characteristics and productivity during summer cultivation between 2015 and 2018. After regional adaptability tests, "Doha" was selected from "Saebong No. 13" as an elite cultivar. The general characteristics of "Doha" include spreading, elliptic leaves, and strong growth. The fruits are long and conical and of a red color. The plant height of "Doha" was similar to that of "Goha," but the number of leaves was lower. The number of flower clusters of "Doha" was 8.6, which was 2.8 fewer than that of the control variety, "Goha," with 11.4. The average fruit weight of "Doha" was 13.9 g, which was 4.9 g heavier than that of "Goha." The fruit hardness of "Doha" was 35.5 g·mm^-2, which was 9.4 g·mm^-2 harder than that of "Goha." The marketable yield of "Doha" was 26,971 kg·ha^-1, 125% more than that of "Goha" with 21,479 kg·ha^-1. The findings of this study suggest that "Doha" is a hard fruit and high-yielding variety of ever-bearing strawberries that could increase farming income when distributing to farmers.

• 보건행정학회지
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• 제9권1호
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• pp.30-71
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• 1999

There has been a dramatic increase in public awareness regarding dementia during recent years. However, dementia remains a family affair and patients do not receive adequate care in Korea. This study aims to assist patients and their caregivers by establishing Home and Community based Long-Term Care in a city. The data collected for analysis include five main categories: dementia prevalence, limitations of daily activities of patients, burden of caregivers, the services that patient's family want to utilize, the resources that handle dementia in the community. Major findings can be summarized as follows: 1)The prevalence rate of dementia for elderly people is 13.1 per 100 persons. Alzheimer's disease amount to 38.9% of dementia patients and vascular dementia account for 36.7% of them 2)Eight out of ten patients have mild dementia. Almost all patients have normal ADL. IADL, however, shows different picture. In every items of IADL, about 60% of patients reveals some limitations. 3)The proportion of patients who had medical diagnosis is as low as 20%. Families of patients think dementia as normal aging process and medical doctors in the community do not give special concern to dementia patients. 4)Caregivers does not have proper social support. They suffer from long care time, experience large obstacles in respect of health, daily living, and social activity. 5)Health center and Community welfare center have launched some programs-consultation, home-visiting nursing, day care center, voluntary force mobilization and so on-for dementia patients. But they do not perform expected roles and functions because of lack of skilled personnels and inadequate coordination of relevant organizations for dementia care. 6)Families of dementia patients prefer home helper and home-visiting nurse to hospitalization. For the future, however, demand for institution-based long-term services will increase. We develope community dementia care model based on above findings as follows: 1)Health center execute community cardiovascular control program for the prevention of vascular dementia. 2)Refer to epidemiologic characteristics of patients and preference of family, the most urgent task for dementia care in this city is to expand and organize Home and Community based Long-Term Care. 3)For the continuous and comprehensive care, care plan for a patient must be prepared. Case management team should be builded to prepare this plan and coordinate relevant resources. 4)Special long-term care unit for dementia will be needed in a near future. This unit should have multiple functions, such as day-care center, short stay facility, training center for relevant personnels, besides long-term nursing home considering effective care of dementia and efficient operation of the facility. 5)Voluntary workers deserve their due efforts. Incentive mechanisms must be developed to activate voluntary activities.