• Journal of Korean Neurosurgical Society
• /
• v.59 no.4
• /
• pp.392-399
• /
• 2016

Objective : Brain metastases in gynecologic cancer (ovarian, endometrial, and cervical cancer) patients are rare, and the efficacy of Gamma Knife Radiosurgery (GKRS) to treat these had not been evaluated. We assessed the efficacy of GKRS and prognostic factors for tumor control and survival in brain metastasis from gynecologic cancers. Methods : This retrospective study was approved by the institutional review board. From May 1995 to October 2012, 26 women (mean age 51.3 years, range 27-70 years) with metastatic brain tumors from gynecologic cancer were treated with GKRS. We reviewed their outcomes, radiological responses, and clinical status. Results : In total 24 patients (59 lesions) were available for follow-up imaging. The median follow-up time was 9 months. The mean treated tumor volume at the time of GKRS was $8185mm^3$ (range $10-19500mm^3$), and the median dose delivered to the tumor margin was 25 Gy (range, 10-30 Gy). A local tumor control rate was 89.8% (53 of 59 tumors). The median overall survival was 9.5 months after GKRS (range, 1-102 months). Age-associated multivariate analysis indicated that the Karnofsky performance status (KPS), the recursive partitioning analysis (RPA) classification, and the number of treated lesions were significant prognostic factors for overall survival (HR=0.162, p=0.008, HR=0.107, p=0.038, and HR=2.897, p=0.045, respectively). Conclusion : GKRS is safe and effective for the management of brain metastasis from gynecologic cancers. The clinical status of the patient is important in determining the overall survival time.

• Archives of Plastic Surgery
• /
• v.35 no.5
• /
• pp.539-544
• /
• 2008

Purpose: There have been limited reports on breast reconstruction after excision of phyllodes tumor. This paper reports four patients who had immediate reconstruction of the breast following excision of phyllodes tumor. Methods: We retrospectively reviewed the medical records of 14 patients from March 2000 to March 2008. Clinical data were analyzed including age, presenting symptoms and signs, type of surgery and metastasis. Results: The mean age was 38.6 years. The mean follow-up period was 40.6 months. Reconstruction was performed with latissimus dorsi musculocutaneous flap in 3 patients and transverse rectus abdominis musculocutaneous flap in 1 patient. Other cases were covered with skin graft or primary repair. 2 local recurrent cases were noted. Conclusion: The breast affected by phyllodes tumor must undergo complete excision. Followed by mastectomy, immediate reconstruction of breast improved cosmetic results, and allowed a wider surgical excision margin of tumor.

• Journal of Korean Foot and Ankle Society
• /
• v.17 no.3
• /
• pp.215-219
• /
• 2013

Purpose: To review the outcomes of surgical treatment for superficial peroneal nerve entrapment. Materials and Methods: Ultrasonogram was used for diagnosis and surgical treatment. Seven superficial peroneal nerve entrapment were surgically treated with follow up of average 16 months (range, 6~29 months). Three patients were male and four patients were female with mean age 36.7 years (range, 19~51 years). Four cases developed after repetitive ankle sprain and three cases had no etiology. Results: Operation was performed mini-open and subcutaneous fasciotomy under local anesthesia. The results were excellent in two cases, good in four cases, fair in one case. Conclusion: Ultrasonogram was useful for diagnosis and surgical treatment of superficial peroneal nerve entrapment syndrome.

• The Transactions of The Korean Institute of Electrical Engineers
• /
• v.59 no.8
• /
• pp.1497-1505
• /
• 2010

The present study was performed to investigate the effect of aging on muscular activity of older subjects under the condition of fixed load muscle contraction. SEMG signals were recorded from old (46 women) and young (45 women) groups performing sustained isometric elbow flexion contraction with a fixed load during 30 seconds. Linear regression and mean square error (MSE) analysis with four characteristic variables (ARV, RMS, MDF, MNF) were used to compare the age-related difference (of local muscle fatigue and fluctuation of the amplitude and frequency) in the SEMG signal. The main results can be summarized as follows: During sustained muscle contraction with a fixed load: i) the MSE values of amplitude (ARV, RMS) and frequency (MDF, MNF) variables were more than 30% higher for the young than for the old adults; ii) the measures of local muscle fatigue (slope of the MDF and MNF) indicated greater fatigue in the old; and iii) the rate of increase of the SEMG amplitude was higher for the young than the old.

• Korean Parent-Child Health Journal
• /
• v.3 no.2
• /
• pp.25-40
• /
• 2000

The purpose of this study is to identify the sleep/activity patterns of neonates and to provide a baseline data in developing an effective maternal-child nursing intervention strategies. The subjects of this study were 57 normal newborn babies from birth to 4 weeks of age, who visited the Postpartum Care Center and two General Hospitals and One Local clinic in Taejon. The data were collected from October 28th, 1999 to April 28th, 2000. The instrument used in this study was NCASA developed by Barnard and validated by the Academic Society of Parent-Child Health. The data were analyzed with the SPSS PC+ 7.5 for window program using means, standard deviation, one-way ANOVA. The results of this study were as follows: 1. The mean amount of daytime sleep was 7.45 hours, nighttime sleep was 4.27 hours, and the total daily sleep was 11.72 hours. The mean amount of longest sleep period was 4.32 hours. The mean regularity of daytime sleep was 35.55%, the nighttime sleep was 44.82%, and the total daily sleep was 39.02%. The mean frequency of nighttime awakenings was 2.44 times. 2. The mean amount of daytime awake periods was 8.54 hours, the nighttime awake periods was 3.72 hours, and the daily total awake periods was 12.27 hours. The mean amount of the longest awake period was 3.98 hours. 3. The mean frequency of daytime feeding was 5.18 times, the nighttime feeding was 2.50 times, and the total daily feeding was 7.49. The mean of regularity of total daily feeding was 61.34%. 4. According to an analysis of sleep patterns based on newborn's age, there were some statistically significant differences noted in the following factors ; amount of nighttime sleep (F=7.65, p=.002), longest sleep period(F=5.84, P=.006). 5. According to an analysis of activity patterns based on newborn's age, there were some statistically significant differences noted in the following factors ; amount of nighttime activity (F=7.64, P=.002), longest activity period (F=4.34, P=.020), frequency of nighttime feeding(F=3.89, p=.029), frequency of total daily feeding(F=3.76, P=.033), and regularity of daily feeding(F=4.66, P=.016). In conclusion, the newborn baby slept more during the daytime than nighttime and more active during the daytime. And there were some irregular sleep/activity pattern noted during 1 to 2 weeks of newborn baby. The results of this study will contribute to maternal-child health nursing practice and nursing research, and provide an information to parents about what to expect their newborn baby.

• Journal of Chest Surgery
• /
• v.29 no.5
• /
• pp.542-547
• /
• 1996

All patients who underwent video-assisted thoracic surgery (VATS) for diagnostic purposes from Jan. 1992 to Aug. 1995 were reviewed. The total number of patients were 111 with 57 male and 54 female, and the mean age was 49 years (range 1 to 74). Multiple biopsies from more than one location were performed in 17 patients , pleural biopsies were performed In 49 patients, lung biopsies in 43 patients, mediastinal mass or Iymph node biopsies in 33 patients, and two pericardium biopsies and one dia- phragm biopsy, for a total of 128 biopsies. Seventeen pleural biopsy cases and one lung biopsy case underwent operation under local anesthesia , the rest were performed under general anesthesia. In patients who underwent lung biopsy, the mean age was 49.1 ye rs (range 22~ 73). The operating time was 40 to 170 minutes (mean 97), intravenous or intramuscular injection for pain control was required 0 to 22 times(mean 4.7), and chest tube was inserted from 1 to 26 days(mean 7). In all patients except two, a diagnosis was obtained from the biopsy and complication was encountered in one patient in whom intraoperative paroxysmal atrial tachycardia was detected. In 7 patients, a thorn- cotomy had to be done due to pleural adhesion or intraoperative bleeding, and 7 patients had postoperative complications associated with the chest tube. In the pleural biopsy group, the mean age was 49 years (range 17~ 74). The operating time was 25 to 80 minutes (mean 49), intravenous or intramuscular injection for pain control was needed 0 to 20 times (mean 3.6), and the chest tube was i.nserted for 0 to 67 days(mean 9.8). In all the patients, a diagnosis was possible. The chest tube was inserted for longer than 7 days in 11 patients. In the Iymph node biopsy roup, the mean age was 44.2 years (range 1 ~ 68). The operating time was )0 to 3)5 minutes(mean 105), pain control was required 0 to 15 times(mean 3.2), and a chest tube was kept in place for 1 to 36 days(mean 6.1). In one patient, a diagnosis was not possible and a chest tube was kept in place for longer than 7 days in 7 patients. In the multiple biopsy group, the mean age was 53.1 years(range 20~ 71). The operating time was 15 to 165 minutes(mean 85), and pain control was done from 0 to 17 times(mean 3.1). The chest tube was kept in place for 1 to 16 days (mean 7.9).

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
• /
• v.4 no.1
• /
• pp.12-18
• /
• 1991

A retrospective review of clinical records of 34 cases with polypoid vocal folds who underwent endolaryngeal microsurgery was carried out. The results were followings; 1) The incidence was high in elder age group(mean age : 53.7 years old). 2) Bilateral lesions were much more frequent than unilateral ones(67.6% vs. 32.4%). 3) Nine out of 34 patients had associated local pathologies and nine out of 34 patients had associated systemic pathologies. 4) Smoking appeared to be the most dominant predisposing factor(76.5%). 5) Maximal phonation time was decreased in 10 cases out of 14 cases(71.4%) and phonation quotient was increased in 9 cases out of 14 cases(64.3%). 6) All the cases were treated with sucking technique and the voice quality was improved in 32 cases(94.1%) The average duration for voice improvement was 2.8 months.

• The Korean Journal of Pain
• /
• v.23 no.2
• /
• pp.147-150
• /
• 2010

Background: Chronic low back pain can be a manifestation of lumbar degenerative disease, herniation of intervertebral discs, arthritis, or lumbar stenosis. When nerve roots are compromised, low back pain, with or without lower extremity involvement, may occur. Local inflammatory processes play an important role in patients with acute lumbosciatic pain. The purpose of this study was to assess the value of erythrocyte sedimentation rate (ESR) and high sensitivity C-reactive protein (hsCRP) measurements in patients with chronic low back pain or radiculopathy. Methods: ESR and hsCRP were measured in 273 blood samples from male and female subjects with low back pain and/or radiculopathy due to herniated lumbar disc, spinal stenosis, facet syndrome, and other diseases. The hsCRP and ESR were measured prior to lumbar epidural steroid injection. Results: The mean ESR was 18.8 mm/h and mean hsCRP was 1.1 mg/L. ESR had a correlation with age. Conclusions: A significant systemic inflammatory reaction did not appear to arise in patients with chronic low back pain.

• The Journal of Korean Society for Radiation Therapy
• /
• v.9 no.1
• /
• pp.50-55
• /
• 1997

The optimal management of uveal melanoma is still a matter of controversy. To determine the effect of Gamma Knife surgery for patients with uveal malanoma. the authors reviewed the results of 5 patients underwent Gamma Knife sugery between Sep. 1993 and Dec. 1996. The mean age was 60.7 years ranging from 42.5 to 76.5 years. Median follow-up was 13.29 months and the patient with follow up period more than 6 months was 4. The mean tumor volume was $3442 mm^3$(mean diameter 15.3 mm) and all patients were irradiated with a mean maximum dose of 74Gy(range $60\~80\;Gy$), using the $50\%$ isodose. After Gamma Knife surgery. one pateint showed complete disapperance in tumor size with follow-up 32 months, one enucleation due to progression, and 2 no interval change. In regard to vision, one patient blind. one enucleation, and 2 patients had no interval change. According to our experiences, Gamma Knife surgery for uveal melanoma be able to achieve local tumor control, spare the eyeball, and have possibility of save vision.

• Korean Journal of Agricultural and Forest Meteorology
• /
• v.1 no.1
• /
• pp.41-51
• /
• 1999

This study was conducted to investigate the effects of local climatic conditions on the annual increment of Korean white pine planted in Gapyung and Yaungdong. For this, stand variables such as mean DBH, mean height, basal area per hectare, and volume per hectare by stand age were measured and summarized for each locality. Based on these statistics, annual increments for 8 years from stand age 10 to 18 were calculated for each of stand variables. A topoclimatological technique which makes use of empirical relationships between the topography and the weather in study sites was applied to produce normal estimates of monthly mean, maximum, minimum temperatures, relative humidity, precipitation, and hours of sunshine. Then, the yearly climatic variables from 1990 to 1997 for each study site were derived from the spatial interpolation procedures based on inverse- distance weighting of the observed deviation from the climatic normals at the nearest 11 standard weather stations. From these estimates, 17 weather variables such as warmth index, coldness index, index of aridity etc., which affect the tree growth, were computed on yearly base for each locality. The deviations of measured annual increments from the expected annual increments for 8 years based on yield table of Korean white pine were then correlated with and regressed on the yearly weather variables to examine effects of local climatic conditions on the growth. Gapyung area provides better conditions for the growth of Korean white pine in the early stage than Youngdong area. This indicates that the conditions such as low temperature, high relative humidity, and large amount of precipitation provide favor environment for the early growth of Korean white pine. A ccording to the correlation and regression an analysis using local climatic conditions and annual increments, the growth pattern of Gapyung area corresponds to this tendency. However, it was found that the relationship between annual increments and local climatic conditions in Youngdong area shows different tendency from Gapyung. These results mean that the yearly growth pattern could not sufficiently be explained by climatic conditions with high variance in yearly weather variables. In addition, the poor growth in Youngdong area might not only be affected by climatic conditions, but also by other environmental factors such as site quality.