• 동양고전연구
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• 제68호
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• pp.345-377
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• 2017

본고는 퇴계(退溪)와 율곡(栗谷) 이후 조선 성리학을 주도했던 대표적인 성리학자인 여헌(旅軒) 장현광(張顯光)(1554~1637)의 학교 교육, 특히 향교(鄕校) 교육(敎育)에 대한 입장과 구체적인 활동을 검토하고, 그것의 도덕교육적 의미를 정리한 것이다. 16세기를 전후한 시기부터 구체화된 향교 교육의 폐단에 대해 퇴계와 율곡은 모두 그 문제점을 인지하고 있었지만, 이에 대한 처방에서는 구별되는 입장을 드러냈다. 퇴계가 향교 교육의 폐단을 지적하면서 유학교육의 면모를 일신하기 위해 서원(書院)의 건립과 위상 강화에 주목하였다면, 율곡은 관학 교육기관으로서 향교의 교육 개혁에 보다 관심을 기울였고, 이를 통해 학교 교육의 면모를 일신하고 인재 양성과 윤리기강의 확립을 추구하였다. 본고에서는 퇴계와 율곡의 구별되는 학교 교육 개혁에 대한 입장에 유의하면서 여헌의 학교 교육에 입장을 고찰하였다. 특히 임진왜란 이후 피폐해진 향촌 사회의 도덕 질서 회복에 주목한 그의 문제의식이 어떻게 향교 교육과 연결되고, 그 의미가 무엇인지 분석하고자 하였다. 아울러 그의 향교 교육에 대한 구체적인 입장을 그가 제시한 인동 향교의 교육 조목을 통해 체계적으로 정리 분석하였으며, 이를 통해 그가 의도한 향교 교육의 내용과 실체가 무엇이었는지도 함께 검토하였다. 나아가 여헌의 향교 교육에 대한 관심과 활동이 도덕교육적으로 어떠한 의미가 있는지를 살피고, 현재 교육 현실과 연관하여 어떤 시사점을 주는지 시론적(試論的)인 입장을 제시하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권5호
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• pp.1771-1777
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• 2012

The impact of anatomic resection (AR) as compared to non-anatomic resection (NAR) for hepatocellular carcinoma (HCC) as a factor for preventing intra-hepatic and local recurrence after the initial surgical procedure remains controversial. A systematic review and meta-analysis of nonrandomized trials comparing anatomic resection with non-anatomic resection for HCC published from 1990 to 2010 in PubMed and Medline, Cochrane Library, Embase, and Science Citation Index were therefore performed. Intra-hepatic recurrence, including early and late, and local recurrence were considered as primary outcomes. As secondary outcomes, 5 year survival and 5 year disease-free survival were considered. Pooled effects were calculated utilizing either fixed effects or random effects models. Eleven non-randomized studies including 1,576 patients were identified and analyzed, with 810 patients in the AR group and 766 in the NAR group. Patients in the AR group were characterized by lower prevalence of cirrhosis, more favorable hepatic function, and larger tumor size and higher prevalence of macrovascular invasion compared with patients in the NAR group. Anatomic resection significantly reduced the risks of local recurrence and achieved a better 5 years disease-free survival. Also, anatomic resection was marginally effective for decreasing the early intra-hepatic recurrence. However, it was not advantageous in preventing late intra-hepatic recurrence compared with non-anatomic resection. No differences were found between AR and NAR with respect to postoperative morbidity, mortality, and hospitalization. Anatomic resection can be recommended as superior to non-anatomic resection in terms of reducing the risks of local recurrence, early intra-hepatic recurrence and achieving a better 5 year disease-free survival in HCC patients.

• Archives of Plastic Surgery
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• 제36권3호
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• pp.344-347
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• 2009

Purpose: Malignant soft tissue tumors, known as sarcomas, are well known to be locally aggressive, frequently metastatic, and highly recurrent. In other hands, intermediate soft tissue tumors often recur locally with adjacent tissue infiltration so the clinical management is difficult as sarcoma. In the present study, we evaluate the clinical course of the intermediate soft tissue tumors and consider the management plan for those. Methods: From March, 1998 to April 2008, total 3 patients of intermediate soft tissue tumors underwent operations. A patient with fibrohistiocytic neoplasm, a free flap reconstruction was performed, and he underwent several more operations because of recurrences. Other patients with desmoids - type fibromatosis showed local invasion and adhesion, and one of them underwent reoperation due to local recurrence. Results: 2 of 3 patients underwent recurrences of tumors and reoperations were performed. In another patient with no recurrence, follow-up period was just 5 months, so there may be recurrence of tumor in long term follow-up. Conclusion: The clinical course of intermediate soft tissue tumors shows high recurrence rate. So clinically, intermediate soft tissue tumors should be considered as sarcomas. The successful management requires wide resection, carefully planned reconstruction, and close follow up with radiologic evaluation.

• Investigative Magnetic Resonance Imaging
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• 제10권2호
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• pp.121-125
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• 2006

두피의 융기성 피부섬유육종이 국소 재발한 48세 남자의 예를 보고하고자 한다. MR영상 소견상 두피의 피부와 피하층에 T1 강조영상에서 저신호강도를 T2 강조영상에서 중등도 고신호강도를 지닌 종괴가 있었고, 조영증강 영상에서 강하게 조영증강되는 종괴는 피부와 피하 및 모상층(galea)으로 파급되는 소견을 보였다. 두피의 융기성 피부섬유 육종은 매우 드문 병변이나 침습적인 종양으로서, MR 영상에서 주변 조직으로의 병변 파급을 진단하고 초기에 광범위 국소절제술을 시행하는 것이 재발을 방지하는 데 중요하다.

• Journal of Chest Surgery
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• 제40권5호
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• pp.395-397
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• 2007

지방모세포종은 드문 양성, 간질기원의 종양으로 주로 유아 및 소아에서 발생한다. 국한형과 미만형의 두 종류가 있으며 전형적으로 사지에서 발생하고, 그 밖에 체간, 두경부, 그리고 후복막강에서 발생한다. 지방모세포종은 국소 침윤 및 재발하는 성질이 있으며, 빠르게 성장하지만, 아직 전이된 예가 보고된 적이 없는, 예후가 좋은 종양이다. 완전 절제가 필요하며, 장기적인 추적관찰이 필요하다.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2001년도 춘계종합학술대회
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• pp.696-699
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• 2001

최근 인터넷 사용의 증가와 더불어 네트워크 기반의 해킹피해가 증가하고 있다. 해킹을 탐지하기 위한 많은 연구가 진행중이고 여러 가지 탐지 도구들이 개발되어 있다. 본 연구에서는 이러한 해킹 기법 중에서 로컬 LAN환경에서 모든 네트워크 트래픽을 분석하여 불법적으로 정보를 수집하는 스니핑 탐지 및 관리 도구를 개발하였다. 스니핑 관리 및 탐지도구는 두 가지의 모듈로 구성되어 있다. 즉 스니핑 탐지모듈과 스니핑 관리지 모듈이다. 스니핑 탐지 탐지 도구는 임의의 host로부터의 침입을 발견한다. 그리고 스니핑 관리 도구에서는 스니퍼에 대한 정보를 웹 브라우저 상에 보여준다.

• 복식문화연구
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• 제8권1호
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• pp.77-86
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• 2000

The purpose of this study is to identify the nature and trend of multinational corporations and to examine strategies for survival of local companies in newly-rising markets which stand against huge multinational corporations, through case study. This research has been done by the literature review of the articles, books and the case study. The results were as follow : First, if the pressure for the globalization of a industry is low and the possibility of overseas transfer of the competitive property of corporations are bare, the intensive strategy for the protection of a national market can be used against the invasion of a multinational corporations. Second, if the pressure for the globalization is still low and the retaining property can be transferred to abroad, a company can be expended to several foreign markets in the limited scope, using the success in a national market as a stepping-stone. Third, In case the pressure for the globalization is high and the competitive property of corporations are effective only in a national market, corporations can survive individually and continuously through the reorganization of corporation's property, which is the survival strategy against multinational corporations. Forth, if the pressure for the globalization is high and the property of corporations can be transferred to abroad, it is possible for corporations to compete with the multinational corporations confidently.

• 대한수의학회지
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• 제54권1호
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• pp.7-12
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• 2014

Peripheral nerve sheath tumors (PNSTs) are heterogeneous tumor groups of peripheral nerves that originate from either Schwann cells or modified Schwann cells, fibroblasts, or perineural cells. In this study, signalment and clinical data such as tumor location and size were evaluated for 15 cases of PNSTs collected from local animal hospitals. The mean age of dogs with malignant PNST was higher than that of dogs with benign PNST. Additionally, the male to female ratio in dogs with PNST was 1 : 4. In dogs with PNST, the primary sites of involvement were the hindlimb, forelimb, around the mammary glands, the neck, and the abdomen. Histiopathologic examination revealed that eight PNSTs were benign and seven were malignant. The tumor cells were composed of loosely to densely arranged interlacing bundles and wavy spindle cells arranged in short bundles, palisading, and whirling. High mitotic figures, local invasion, multifocal necrosis and atypical multinucleated giant cells were observed in malignant PNST cases. All PNSTs showed immunoreactivity for vimentin and S-100. However, only 93.3% and 73.3% were immunoreactive for NSE and GFAP, respectively. Overall, these results indicated that immunohistochemical markers such as vimentin, S-100 and NSE could help confirm the diagnosis of canine PNSTs.

• Biomolecules & Therapeutics
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• 제29권3호
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• pp.263-267
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• 2021

Periodontal disease is primarily associated with bacterial infection such as dental plaque. Dental plaque, an oral biofilm harboring a complex microbial community, can cause various inflammatory reactions in periodontal tissue. In many cases, the local bacterial invasion and host-mediated immune responses lead to severe alveolar bone destruction. To date, plaque control, non-surgical, and surgical interventions have been the conventional periodontal treatment modalities. Although adjuvant therapies including antibiotics or supplements have accompanied these procedures, their usage has been limited by antibiotic resistance, as well as their partial effectiveness. Therefore, new strategies are needed to control local inflammation in the periodontium and host immune responses. In recent years, target molecules that modulate microbial signaling mechanisms, host inflammatory substances, and bone immune responses have received considerable attention by researchers. In this review, we introduce three approaches that suggest a way forward for the development of new treatments for periodontal disease; (1) quorum quenching using quorum sensing inhibitors, (2) inflammasome targeting, and (3) use of FDA-approved anabolic agents, including Teriparatide and sclerostin antibody.

• Parasites, Hosts and Diseases
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• 제60권1호
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• pp.57-63
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• 2022

When free-ranging birds are accidentally killed or die, there may be greater potential for their associated ticks to detach, seek alternate hosts, and become established. We examined 711 carcasses of 95 avian species for ticks at a stopover island of migratory birds in the Republic of Korea where only Ixodes nipponensis and I. persulcatus were previously reported from local mammals and vegetation. A total of 16 ticks, I. turdus and Haemaphysalis flava, were collected from 8 fresh carcasses belonging to 5 avian species. Despite their known abundance on migratory birds and mainland Korea, these species had not colonized the isolated insular ecosystem possibly due to the low abundance and diversity of local hosts. The results imply that increasing human impact, such as the anthropogenic mortality of migratory birds and the introduction of non-native mammalian hosts, will increase the potential invasion and colonization risk of ticks. This finding also suggests that tick surveillance consisting of fresh carcasses of dead migratory birds may provide additional information, often ignored in surveillance of ticks on live birds, for the potential introduction of non-native ticks and associated pathogens affecting animal and human health.