• Title/Summary/Keyword: Local control rate

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The effects according to the timing of thoracic radiotherapy in limited stage small cell lung cancer (제한병기 소세포폐암에서 흉부 방사선 치료의 도입 시기에 따른 치료 효과의 비교 분석)

  • Park, Sang Ki;Kim, Geun Hwa;Jeong, Seong Su;Shin, Kyoung Sang;Kim, Ae Kyoung;Cho, Hai Jeong;Suhr, Jee Won;Kim, Jae Sung;Cho, Moon June;Kim, Ju Ock;Kim, Sun Young
    • Tuberculosis and Respiratory Diseases
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    • v.43 no.6
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    • pp.903-915
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    • 1996
  • Background: Combination chemotherapy is now considered to be the cornerstone of small cell lung cancer (SCLC). management but the optimal management of limited SCLC is not well defined. The role of thoracic radiotherapy (TRT) is less well established. Recent meta-analyses reports revealed that TRT combined with chemotherapy produce "good" local control and prolonged survival. But other reports that survival was not changed. The liming, dose, volume and fractionation for TRT with the combined chemotherapy of SCLC remains unsettled. In this study, we analyzed the effects according to the timing of thoracic radiotherapy in limited SCLC. Method: All fifty one patients received cytoxan, adriamycin and vincristine(CAV) alternating with etoposide and cisplatin(VPP) every 3 weeks for 6 cycles were randomized prospectively into two groups: concurrent and sequential. 27 patients received 4500cGy in 30 fractions(twice daily 150cGy fractional dose) over 3 weeks 10 the primary site concurrent with the first cycle of VPP(concurrent gorup). 24 patients received 4000 to 5000cGy over 5 or 6 weeks after completion of sixth cycles of chemotherapy(sequential group). Results: 1. Response rates and response duration : Response rates were not significantly different between two groups(p=0.13). But response duration was superior in the concurrent group(p=0.03). 2. Survival duration was nor different between two groups(p=0.33). 3. Local control rate was superior in the concurrent group(p=0.00). 4. Side effects and toxicities: Hematologic toxicities, especially leukopenia, infection and frequency of radiation esophagitis were higher in the concurrent group (p=0.00, 0.03, 0.03). Conclusion: The concurrent use of TRT with chemotherapy failed to improve the survival of limited stage SCLC patients compared with the sequential use of TRT but response duration and local control rate were superior in the concurrent group. Frequency of radiation esophagitis, life threatening hematologic toxicities and infection were more frequent in the concurrent group than sequential group. So, the selection of an optimal schedule of chemotherapy combined with TRT that would lead to a major increase in survival with minimal toxicity is remained to be validated in large scale study in the future.

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Development of the Serial Data Transmission System for Pneumatic Valve System Control

  • Kim, Dong-Soo;Choi, Byung-Oh;Seo, Hyun-Seok
    • 제어로봇시스템학회:학술대회논문집
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    • 2003.10a
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    • pp.1152-1156
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    • 2003
  • For pneumatic valve system control, we need a serial data transmission system with high speed and reliability for information interchange between main computer and I/O devices. This paper presents a set of design techniques for a data communication system that is mainly used for pneumatic valve system control. For this purpose, we first designed hardware modules for an interface between central control module and local node that handles the operation of solenoid control valves. in addition, we developed a communication protocol for construction of rs-485 based multi-drop network and this protocol is basically designed with a kind of polling technique. Finally we evaluated performance of the developed system. the field test results show that, even under high noise environment, the data transmission of 375kbps rate is possible up to 1,500meter without using repeater. In addition, the system developed in this research is easily to be extended for a communication network because of its modular structure.

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Practical Use of Cancer Control Promoters in Municipalities in Japan

  • Yako-Suketomo, Hiroko;Katanoda, Kota;Sobue, Tomotaka;Imai, Hirohisa
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.19
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    • pp.8239-8244
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    • 2014
  • The Cancer Control Act in Japan became effective in 2006. In Ibaraki, Toyama, and Hyogo prefectures, the Cancer Control Promoter (CCP) plan was created to strengthen partnerships for cancer prevention. This study aimed to examine the curre nt status of CCP utilization and analyze relationships with intersectoral collaboration, both within the government and with outside partners. In 2008, we mailed questionnaires to 100 administrators responsible for disease prevention and health promotion in municipal governments of the three prefectures. Ninety-one administrators responded (response rate, 91.0%). We analyzed responses to questions regarding whether or not the municipalities had used CCPs. Items assessing intersectoral collaboration examined municipality characteristics and relationships with outside partners and sectors specializing in areas other than community health. Among 90 administrators with valid data, 33 municipalities (36.7%) used CCPs while 57 (63.3%) did not. The Fisher's exact test revealed that intersectoral collaboration for using CCPs was associated with communication with all of the municipal government sectors not related to health. The present study indicated that CCPs were not consistently used in municipalities. However, we found that intersectoral collaborations, especially within the local government, may be related to the practical use of CCPs. This, in turn, may result in effective cancer control and prevention, as well as improvement in community health.

Intelligent Control Algorithm for the Adjustment Process During Electronics Production (전자제품생산의 조정고정을 위한 지능형 제어알고리즘)

  • 장석호;구영모;고택범;우광방
    • Journal of Institute of Control, Robotics and Systems
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    • v.4 no.4
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    • pp.448-457
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    • 1998
  • A neural network based control algorithm with fuzzy compensation is proposed for the automated adjustment in the production of electronic end-products. The process of adjustment is to tune the variable devices in order to examine the specified performances of the products ready prior to packing. Camcorder is considered as a target product. The required test and adjustment system is developed. The adjustment system consists of a NNC(neural network controller), a sub-NNC, and an auxiliary algorithm utilizing the fuzzy logic. The neural network is trained by means of errors between the outputs of the real system and the network, as well as on the errors between the changing rate of the outputs. Control algorithm is derived to speed up the learning dynamics and to avoid the local minima at higher energy level, and is able to converge to the global minimum at lower energy level. Many unexpected problems in the application of the real system are resolved by the auxiliary algorithms. As the adjustments of multiple items are related to each other, but the significant effect of performance by any specific item is not observed. The experimental result shows that the proposed method performs very effectively and are advantageous in simple architecture, extracting easily the training data without expertise, adapting to the unstable system that the input-output properties of each products are slightly different, with a wide application to other similar adjustment processes.

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Treatment Planning Guideline of EBT Film-based Delivery Quality Assurance Using Statistical Process Control in Helical Tomotherapy (토모테라피에서 통계적공정관리를 이용한 EBT 필름 기반의 선량품질보증의 치료계획 가이드라인)

  • Chang, Kyung Hwan
    • Journal of radiological science and technology
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    • v.45 no.5
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    • pp.439-448
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    • 2022
  • The purpose of this study was to analyze the results from statistical process control (SPC) to recommend upper and lower control limits for planning parameters based on delivery quality assurance (DQA) results and establish our institutional guidelines regarding planning parameters for helical tomotherapy (HT). A total of 53 brain, 41 head and neck (H & N), and 51 pelvis cases who had passing or failing DQA measurements were selected. The absolute point dose difference (DD) and the global gamma passing rate (GPR) for all patients were analyzed. Control charts were used to evaluate upper and lower control limits (UCL and LCL) for all assessed treatment planning parameters. Treatment planning parameters were analyzed to provide its range for DQA pass cases. We confirmed that the probability of DQA failure was higher when the proportion of leaf open time (LOT) below 100 ms was greater than 30%. LOT and gantry period (GP) were significant predictor for DQA failure using the SPC method. We investigated the availability of the SPC statistic method to establish the local planning guideline based on DQA results for HT system. The guideline of each planning parameter in HT may assist in the prediction of DQA failure using the SPC statistic method in the future.

Venturi Effects Induced by the Local Ventilation Fan in Large-Opening Room-and-Pillar Mining Sites (대단면 갱내 국부 선풍기의 벤츄리(Venturi) 효과 연구)

  • Lee, Chang Woo;Nguyen, Van Duc
    • Tunnel and Underground Space
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    • v.24 no.6
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    • pp.464-472
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    • 2014
  • In large-opening room-and-pillar mining sites, particularly without the devices for the ventilation control, the airflow pattern created by the local fan operation is too complicated to quantify and also shows low ventilation efficiency. This study aims at performing a series of CFD analysis for the so-called venturi effects of the local fans; the effects of increasing airflow rate along the axis downstream of fan resulting from increased kinetic energy and subsequently decreased static pressure in the downstream. Effects of the fan type and installation height are compared. 1 vane-axial fan and 2 propeller fans are analyzed for their venturi effects, while the vane-axial fan was installed at the height of 1.0, 1.5 and 2.0m for comparison. The results can be applied to improve the economy and efficiency of local fans for securing better air quality and work environment management.

Determinants affecting Performance Differences of Korean SME's Subsidiaries in Vietnam (베트남 진출 한국 중소기업의 투자성과 차이를 가져오는 경영관리역량에 대한 사례연구)

  • Han, Jung Wha;Yoon, Dong Jin
    • International Area Studies Review
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    • v.16 no.1
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    • pp.197-220
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    • 2012
  • This study is to understand those determinants of performance differences of Korean small and medium firm's subsidiaries in Vietnam based on the resource based view. We have visited 21 Korean SME's subsidiaries in Hochiminh city area in Vietnam and interviewed CEO of those subsidiaries for 1-2 hours to make each case. Based on case content analysis, we can get those results that eight management capabilities such as securing competent local managers, clear and smooth communication with local employees, establishing good labor-management relations, raising the rate of factory operation and subcontracting, firm specific quality control system, timely financing, establishing good relationships with local communities, and fostering friendly relations with local public officers are major determinants of performance differences. Also we can know that various factors including local experiences in Vietnam have influenced those management capabilities. To be a high performer in Vietnam, foreign subsidiaries of Korean SMEs have to build and develop major management capabilities continuously.

Adaptive-length pendulum smart tuned mass damper using shape-memory-alloy wire for tuning period in real time

  • Pasala, Dharma Theja Reddy;Nagarajaiah, Satish
    • Smart Structures and Systems
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    • v.13 no.2
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    • pp.203-217
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    • 2014
  • Due to the shift in paradigm from passive control to adaptive control, smart tuned mass dampers (STMDs) have received considerable attention for vibration control in tall buildings and bridges. STMDs are superior to tuned mass dampers (TMDs) in reducing the response of the primary structure. Unlike TMDs, STMDs are capable of accommodating the changes in primary structure properties, due to damage or deterioration, by tuning in real time based on a local feedback. In this paper, a novel adaptive-length pendulum (ALP) damper is developed and experimentally verified. Length of the pendulum is adjusted in real time using a shape memory alloy (SMA) wire actuator. This can be achieved in two ways i) by changing the amount of current in the SMA wire actuator or ii) by changing the effective length of current carrying SMA wire. Using an instantaneous frequency tracking algorithm, the dominant frequency of the structure can be tracked from a local feedback signal, then the length of pendulum is adjusted to match the dominant frequency. Effectiveness of the proposed ALP-STMD mechanism, combined with the STFT frequency tracking control algorithm, is verified experimentally on a prototype two-storey shear frame. It has been observed through experimental studies that the ALP-STMD absorbs most of the input energy associated in the vicinity of tuned frequency of the pendulum damper. The reduction of storey displacements up to 80 % when subjected to forced excitation (harmonic and chirp-signal) and a faster decay rate during free vibration is observed in the experiments.

High Performance Coprocessor Architecture for Real-Time Dense Disparity Map (실시간 Dense Disparity Map 추출을 위한 고성능 가속기 구조 설계)

  • Kim, Cheong-Ghil;Srini, Vason P.;Kim, Shin-Dug
    • The KIPS Transactions:PartA
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    • v.14A no.5
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    • pp.301-308
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    • 2007
  • This paper proposes high performance coprocessor architecture for real time dense disparity computation based on a phase-based binocular stereo matching technique called local weighted phase-correlation(LWPC). The algorithm combines the robustness of wavelet based phase difference methods and the basic control strategy of phase correlation methods, which consists of 4 stages. For parallel and efficient hardware implementation, the proposed architecture employs SIMD(Single Instruction Multiple Data Stream) architecture for each functional stage and all stages work on pipelined mode. Such that the newly devised pipelined linear array processor is optimized for the case of row-column image processing eliminating the need for transposed memory while preserving generality and high throughput. The proposed architecture is implemented with Xilinx HDL tool and the required hardware resources are calculated in terms of look up tables, flip flops, slices, and the amount of memory. The result shows the possibility that the proposed architecture can be integrated into one chip while maintaining the processing speed at video rate.

Occupational radiation exposure control analyses of 14 MeV neutron generator facility: A neutronic assessment for the biological and local shield design

  • Swami, H.L.;Vala, S.;Abhangi, M.;Kumar, Ratnesh;Danani, C.;Kumar, R.;Srinivasan, R.
    • Nuclear Engineering and Technology
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    • v.52 no.8
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    • pp.1784-1791
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    • 2020
  • The 14 MeV neutron generator facility is being developed by the Institute for Plasma Research India to conduct the lab scale experiments related to Indian breeding blanket system for ITER and DEMO. It will also be utilized for material testing, shielding experiments and development of fusion diagnostics. Occupational radiation exposure control is necessary for the all kind of nuclear facilities to get the operational licensing from governing authorities and nuclear regulatory bodies. In the same way, the radiation exposure for the 14 MeV neutron generator facility at the occupational worker area and accessible zones for general workers should be under the permissible limit of AERB India. The generator is designed for the yield of 1012 n/s. The shielding assessment has been made to estimate the radiation dose during the operational time of the neutron generator. The facility has many utilities and constraints like ventilation ducts, accessible doors, accessibility of neutron generator components and to conduct the experiments which make the shielding assessment challenging to provide proper safety for occupational workers and the general public. The neutron and gamma dose rates have been estimated using the MCNP radiation transport code and ENDF -VII nuclear data libraries. The ICRP-74 fluence to dose conversion coefficients has been used for the assessment. The annual radiation exposure has been assessed by considering 500 h per year operational time. The provision of local shield near to neutron generator has been also evaluated to reduce the annual radiation doses. The comprehensive results of radiation shielding capability of neutron generator building and local shield design have been presented in the paper along with detailed maps of radiation field.