• 척추신경추나의학회지
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• 제13권1호
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• pp.11-21
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• 2018

Objectives: To evaluate the evidence supporting the effectiveness and safety of Chinese medicine, including Chuna manual therapy, for the treatment ofosteoarthritis. Methods: We conducted a search of 8 electronic databases(Pubmed, Web of Science, EMBASE, Cochrane Library, CAJ, KISTI, NDSL, and RISS) to find all randomized controlled clinical trials that discuss Chuna manual therapy forosteoarthritis till May 2018. Results: Our inclusion criteria selected 7eligible RCTs involving 633 participants. The meta-analysis of 6 studies showed positive results for the useof Chinese medicine, including Chuna manual therapy, for treating knee osteoarthritis. There was no evidence of worsening symptoms or any adverse events. Conclusions: Our systematic review found favorable evidence regardingthe effectiveness of Chinese medicine, including Chuna manual therapy, for treating knee osteoarthritis. However, our systematic review had several limitations owingto the low quality of original articles andadditionalclinical trials would be necessary for stronger evidence.

• 대한치과마취과학회지
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• 제13권4호
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• pp.179-188
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• 2013

Background: Today, there are computer controlled local anesthesia devices used clinically. The main principle is to control injection speed by computer aided system, and it relieves pain. However, there are few objective data considering this subject. In this literature review, we researched studies about computer controlled anesthetic delivery. We compared pain control effect of computer controlled to conventional local anesthetic syringe system. Methods: A bibliographic search in PubMed was performed and we reviewed original articles. Results: There were 18 publications that compared pain control effect of computer controlled to conventional system. There were 8 articles reported of children, similar pain control effect was found in 7 of them. One study showed superior pain control effect of computer controlled anesthetic delivery. For adults, 10 studies showed superior pain control effect in computer aided system. Conclusions: Computer controlled anesthetic delivery has similar or superior pain control effect compared to conventional local anesthetic syringe system. For both children and adults, computer controlled anesthetic delivery could be clinically useful, still it may be more effective for adults.

• The Korean Journal of Pain
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• 제34권4호
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• pp.509-533
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• 2021

Background: Postherpetic neuralgia (PHN) is a refractory complication of herpes zoster (HZ). To prevent PHN, various strategies have been aggressively adopted. However, the efficacy of these strategies remains controversial. Therefore, we aimed to estimate the relative efficacy of various strategies used in clinical practice for preventing PHN using a network meta-analysis (NMA). Methods: We performed a systematic and comprehensive search to identify all randomized controlled trials. The primary outcome was the incidence of PHN at 3 months after acute HZ. We performed both frequentist and Bayesian NMA and used the surface under the cumulative ranking curve (SUCRA) values to rank the interventions evaluated. Results: In total, 39 studies were included in the systematic review and NMA. According to the SUCRA value, the incidence of PHN was lower in the order of continuous epidural block with local anesthetics and steroids (EPI-LSE), antiviral agents with subcutaneous injection of local anesthetics and steroids (AV + sLS), antiviral agents with intracutaenous injection of local anesthetics and steroids (AV + iLS) at 3 months after acute HZ. EPI-LSE, AV + sLS and AV + iLS were also effective in preventing PHN at 1 month after acute HZ. And paravertebral block combined with antiviral and antiepileptic agents was effective in preventing PHN at 1, 3, and 6 months. Conclusions: The continuous epidural block with local anesthetics and steroid, antiviral agents with intracutaneous or subcutaneous injection of local anesthetics and a steroid, and paravertebral block combined with antiviral and antiepileptic agents are effective in preventing PHN.

• 정보처리학회논문지B
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• 제16B권2호
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• pp.123-130
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• 2009

움직임 추정은 동영상 압축에서 영상 화질과 인코더 속도에 대하여 중요한 역할을 하지만, 많은 수행 시간을 요구한다. H.264/AVC에서 움직임 추정에 소요되는 수행 시간을 줄이면서 화질을 유지하기 위하여 본 논문에서는 정화소와 부화소 움직임 추정 기법을 제안하였다. 본 논문에서는 정화소 움직임 추정을 위하여 계층적인 탐색 기법을 사용하였고, 정확한 움직임 추정을 위하여 블록 크기에 따라 부화소 움직임 추정 패턴을 적응적으로 결정하였다. 제안한 정화소 움직임 추정 탐색 기법은 대칭적 십자가-엑스 탐색 패턴, 다중 사각형 탐색 패턴, 다이아몬드 탐색 패턴들로 이루어져 있다. 이 탐색 패턴들은 블록 움직임이 수직으로 크거나 블록 움직임이 크면서 규칙적인 영상에서 국부적 최소화 문제를 해결하고 움직임 추정에 소요되는 시간을 줄이기 위하여 탐색 영역 내에 탐색 점들을 규칙적, 대칭적으로 배치하였다. 제안한 부화소 움직임 추정 탐색 기법은 부화소 움직임 추정을 위하여 기존의 전역 부화소 탐색 패턴, 중앙 편향적 부화소 탐색 패턴과 제안한 부화소 움직임 탐색패턴들을 사용한다. 그리고 블록의 크기에 따라 3가지의 부화소 탐색 패턴들 중 한 패턴이 부화소 움직임 추정을 위해 적응적으로 결정된다. 블록의 크기에 따라 적응적으로 부화소 탐색 패턴이 결정되므로 보다 정확하게 부화소 움직임 추정을 수행할 수 있다. 제안한 기법을 전역 탐색 기법과 비교하였을 때 약 5.2배의 속도 향상을 가져왔으며, 영상 화질에 있어서 약 0.01 (dB)정도 성능 저하를 보였다. 반면에, 비대칭 다중육각형 탐색 기법과 비교하였을 때 움직임 추정 속도와 화질에 있어서 각각 약 1.2배와 약 0.02 (dB)정도 향상을 보였다.

• 한국국방경영분석학회지
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• 제17권1호
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• pp.146-158
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• 1991

In this paper, we deal with the TSP (Traveling Salesperson Problem) which is well-known as NP-complete optimization problem. the TSP is applicable to network routing. task allocation or scheduling. and VLSI wiring. Well known numerical methods such as Newton's Metheod. Gradient Method, Simplex Method can not be applicable to find Global Solution but the just give Local Minimum. Exhaustive search over all cyclic paths requires 1/2 (n-1) ! paths, so there is no computer to solve more than 15-cities. Heuristic algorithm. Simulated Annealing, Artificial Neural Net method can be used to get reasonable near-optimum with polynomial execution time on problem size. Therefore, we are able to select the fittest one according to the environment of problem domain. Three methods are simulated about symmetric TSP with 30 and 50-city samples and are compared by means of the quality of solution and the running time.

• 산업경영시스템학회지
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• 제22권52호
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• pp.97-107
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• 1999

The asymmetric traveling salesman problem is a representative NP-Complete problem. Polynomial algorithm for this problem has not been yet found. So, many heuristic methods have been researched in this problem. We need heuristic methods that produce good answers for some larger problems in reasonable times. 3-opt is well known for the effective local-search heuristic method. It has been used in many applications of the asymmetric traveling salesman problem. This paper discusses 3-opt's properties and ineffective aspects and presents a highly effective heuristic method. 3-opt does not consider good arcs(shorter distance or little cost). This paper presents a fast heuritic algorithm compared with 3-opt by inserting good arcs and deleting related arcs later.

• Smart Structures and Systems
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• 제26권3호
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• pp.345-360
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• 2020

Modern swarm intelligence heuristic search methods are widely applied in the field of structural health monitoring due to their advantages of excellent global search capacity, loose requirement of initial guess and ease of computational implementation etc. To this end, a hybrid strategy is proposed based on butterfly optimization algorithm (BOA) and differential evolution (DE) with purpose of effective combination of their merits. In the proposed identification strategy, two improvements including mutation and crossover operations of DE, and dynamic adaptive operators are introduced into original BOA to reduce the risk to be trapped in local optimum and increase global search capability. The performance of the proposed algorithm, hybrid butterfly optimization and differential evolution algorithm (HBODEA) is evaluated by two numerical examples of a simply supported beam and a 37-bar truss structure, as well as an experimental test of 8-story shear-type steel frame structure in the laboratory. Compared with BOA and DE, the numerical and experimental results show that the proposed HBODEA is more robust to detect the reduction of stiffness with limited sensors and contaminated measurements. In addition, the effect of search space, two dynamic operators, population size on identification accuracy and efficiency of the proposed identification strategy are further investigated.

• Korean Journal of Radiology
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• 제21권7호
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• pp.908-918
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• 2020

Objective: To categorize the radiological patterns of recurrence after bevacizumab treatment and to derive the pooled proportions of patients with recurrent malignant glioma showing the different radiological patterns. Materials and Methods: A systematic literature search in the Ovid-MEDLINE and EMBASE databases was performed to identify studies reporting radiological recurrence patterns in patients with recurrent malignant glioma after bevacizumab treatment failure until April 10, 2019. The pooled proportions according to radiological recurrence patterns (geographically local versus non-local recurrence) and predominant tumor portions (enhancing tumor versus non-enhancing tumor) after bevacizumab treatment were calculated. Subgroup and meta-regression analyses were also performed. Results: The systematic review and meta-analysis included 17 articles. The pooled proportions were 38.3% (95% confidence interval [CI], 30.6-46.1%) for a geographical radiologic pattern of non-local recurrence and 34.2% (95% CI, 27.3-41.5%) for a non-enhancing tumor-predominant recurrence pattern. In the subgroup analysis, the pooled proportion of non-local recurrence in the patients treated with bevacizumab only was slightly higher than that in patients treated with the combination with cytotoxic chemotherapy (34.9% [95% CI, 22.8-49.4%] versus 22.5% [95% CI, 9.5-44.6%]). Conclusion: A substantial proportion of high-grade glioma patients show non-local or non-enhancing radiologic patterns of recurrence after bevacizumab treatment, which may provide insight into surrogate endpoints for treatment failure in clinical trials of recurrent high-grade glioma.

• 한국콘텐츠학회논문지
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• 제14권10호
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• pp.279-286
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• 2014

최근 농산물 전자상거래의 거래액은 지속적으로 상승하고 있으나 농산물을 취급하는 전문몰의 거래액은 감소하고 있는 실정이다. 농산물의 다양한 유통구조에 따라 판매 가격의 차이가 발생하고 있고, 이러한 차이가 소비자들의 구매결정에 영향을 미치고 있다. 본 연구에서는 지방자치단체 농산물 쇼핑몰의 운영 개선 방안을 도출하고자, 영향요인을 품질, 배송, 가격으로 하여 만족과 재구매의도에 미치는 영향에 관하여 검증하고자 하였다. 검증 결과 품질, 배송, 가격이 만족에 유의한 정(+)의 영향을 미치고, 가격과 만족이 재구매 의도에 유의한 정(+)의 영향을 미치지만, 품질과 배송은 재구매의도에 유의한 정(+)의 영향을 미치지 못하는 것으로 나타났다. 영향요인으로 제시한 변수 중 가격에 가장 민감하게 반응하는 것으로 나타나다. 지자체 쇼핑몰의 운영 개선 방안으로 (1) 정확한 제품 정보의 전달, (2) 지속적인 운영 관리, (3) 다양한 이벤트 실시, (4) 소비자에게 다양한 혜택 제공, (5) 다양한 제품 구성, (6) 적절한 판매 방법의 선택, (7) 삼품 검색의 용이성 제공이 필요하며, 상대적으로 다양한 혜택 제공과 검색 용이성이 중요한 것으로 사료된다.

• Journal of Ecology and Environment
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• 제48권2호
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• pp.182-195
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• 2024

Background: Invasive alien plant species (IAP) significantly threaten Nepal's protected areas and local communities. Understanding their distribution, impact, management, and utilization is essential for developing effective management strategies and sustainable utilization practices. The systematic literature review of publications from 2010 to 2023. The search was conducted through the database Nepal Journal online database (NepJOL) and Google Scholar, yielding an initial pool of 4,304 publication. After applying inclusion and exclusion criteria; we meticulously reviewed 43 articles for data extraction. Results: Seventeen IAP are found in protected area, Nepal with the highest prevalence observed in Koshi Tappu Wildlife Reserve, followed by Chitwan and Sukhlaphanta National Park. The most problematic species in terrestrial ecosystems are Mikania micrantha, Lantana camara, and Chromolaena odorata. The grassland ecosystems of wildlife habitats, primarily in the Terai and Siwalik regions, are the most invaded. Various management approaches are employed to mitigate the spread and impact of IAP, including mechanical methods such as uprooting, burning, and cutting. However, these methods are costly, and context-specific interventions are needed. The study also explores the potential use of IAP for economic, ecological, or cultural purposes, such as medicinal properties, energy production potential, and economic viability. Local communities utilize these plants for animal bedding, mulching, green manure, briquette, and charcoal production. Conclusions: Applying silvicultural practices alongside mechanical management is recommended to maintain a healthy terrestrial ecosystem and utilize the removed biomass for valuable products, thereby reducing removal costs and increasing income sources, potentially benefitting both local communities and wildlife in protected areas.