• Journal of Pharmaceutical Investigation
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• v.28 no.4
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• pp.249-255
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• 1998

Solid Lipid Nanoparticle(SLN), one of the colloidal carrier systems, has many advantages such as good biocompatibility, low toxicity and stability. In this paper, the effects of drug lipophilicity and surfactant on the drug loading capacity, particle size and drug release profile were examined. SLNs were prepared by homogenization of melted lipid dispersed in an aqueous surfactant solution. Ketoprofen, ibuprofen and pranoprofen were used as model drugs and tweens and poloxamers were tested for the effect of surfactant. Mean particle size of prepared SLNs was ranged from 100 to 150nm. The drug loading capacity was improved with the most lipophilic drug and low concentration of surfactant. Particle size and polydispersity of SLNs were changed according to the used lipid and surfactant. The rates of drug release were controlled by the loading drug and surfactant concentration. SLN system with effective drug loading efficiency and proper particle size for the intravenous or oral formulation can be prepared by selecting optimum drug and surfactant.

• Steel and Composite Structures
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• v.12 no.3
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• pp.207-230
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• 2012

Nowadays CFRP (Carbon Fiber Reinforced Polymer) became widely used materials for the strengthening and retrofitting of structures. Many experimental and analytical studies are encountered at literature about strengthening beams by using this kind of materials against static loads and cyclic loads such as earthquake or wind loading for investigating their behavior. But authors did not found any study about strengthening of RC beams by using CFRP against low velocity impact and investigating their behavior. For these reasons an experimental study is conducted on totally ten strengthened RC beams. Impact loading is applied on to specimens by using an impact loading system that is designed by authors. Investigated parameters were concrete compression strength and drop height. Two different sets of specimens with different concrete compression strength tested under the impact loading that are applied by dropping constant weight hammer from five different heights. The acceleration arises from the impact loading is measured against time. The change of velocity, displacement and energy are calculated for all specimens. The failure modes of the specimens with normal and high concrete compression strength are observed under the loading of constant weight impact hammer that are dropped from different heights. Impact behaviors of beams are positively affected from the strengthening with CFRP. Measured accelerations, the number of drops up to failure and dissipated energy are increased. Finite element analysis that are made by using ABAQUS software is used for the simulation of experiments, and model gave compatible results with experiments.

• The Journal of Korean Academy of Prosthodontics
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• v.43 no.3
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• pp.379-392
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• 2005

Statement of problem. One of the common problems of dental implant prosthesis is the loosening of the screw that connects each component, and this problem is more common in single implant-supported prostheses with external connection, and in molars. Purpose. The purposes of this study were: (1) to compare the initial abutment screw detorque values of the six different implant-abutment interface designs, (2) to compare the detorque values of the six different implant-abutment interface designs after cyclic loading, (3) to compare the detorque values of regular and wide diameter implants and (4) to compare the initial detorque values with the detorque values after cyclic loading. Material and methods. Six different implant-abutment connection systems were used. The cement retained abutment and titanium screw of each system were assembled and tightened to 32Ncm with digital torque gauge. After 10 minutes, initial detorque values were measured. The custom titanium crown were cemented temporarily and a cyclic sine curve load(20 to 320N, 14Hz) was applied. The detorque values were measured after cyclic loading of one million times by loading machine. One-way ANOVA test, scheffe’s test and Mann-Whitney U test were used. Results. The results were as follows : 1. The initial detorque values of six different implant-abutment connections were not significantly different(p>0.05). 2. The detorque values after one million dynamic cyclic loading were significantly different (p<0.05). 3. The SS-II regular and wide implant both recorded the higher detorque values than other groups after cyclic loading(p<0.05). 4. Of the wide implants, the initial detorque values of Avana Self Tapping Implant, MIS and Tapered Screw Vent, and the detorque values of MIS implant after cyclic loading were higher than their regular counterparts(p<0.05). 5. After cyclic loading, SS-II regular and wide implants showed higher detorque values than before(p<0.05).

• Journal of Environmental Science International
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• v.3 no.3
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• pp.285-296
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• 1994

The objective of this study was to examine and compare to transient response to quantitative and hydraulic shocks which produce equal changes in mass rate of organic feed in aerobic fixed-film process. The general experimental approach was to operate the system at several growth rates under steady-state(pre-shock) conditions, then to apply step changes during day 3 in dilution rate(hydraulic shock) , or feed concentration(Quantitative shock) at the same organic mass loading rate. Performance was assessed in both the transient state and the new steady-state (post- shock). Shock load of different type did not produced equivalent disruptions of effluent quality for equal increases in mass loading rate. Based on effluent concentrations, a hydraulic and a Quantitative shock at the same mass loading caused equal increase in total effluent COD, but the increase was primarily a result of suspended solids the hydraulic shock and COD in the quantitative shock. The time which effluent COD came to peak values were about 32~48 hours at the low organic loads and 52 ~ 72 hours at the high organic loads, respectively A quantitative shock produced a much greater increase in effluent COD than did a hydraulic shock at the same mass loading. Mean and peak values of effluent concentration weve increased in 2.8~4.2 times at low organic loading rate, 5.2~6.6 times at the high organic loading rate, respectively. Key words : Aerobic fixed-film reactor, Quantitative shock, hydraulic shock, mass loading rate.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.24 no.6 s.177
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• pp.1446-1455
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• 2000

Fatigue crack initiation and propagation behavior under cyclic biaxial loading has been investigated using thin-walled tubular specimen with a hole. Two types of biaxial loading system, i.e. cyclic tensile loading with super-imposed static torsional load and cyclic torsional loading with superimposed static tensile load, with various values of the biaxial loading ratio, $\tau$ s/ $\sigma$ max (or $\tau$ max/ $\sigma$s) were employed. Fatigue tests show that fatigue crack near the hole initiates and propagates at 900 and 450 direction to the longitudinal direction of the specimen under cyclic tensile and torsion loading with static biaxial stress, respectively, and the static biaxial stress doesn't have any great influence on fatigue crack initiation and growth direction. Stress analysis near the hole of the specimen shows that the crack around the hole initiates along the plane of maximum tangential stress range. Fatigue crack growth rates were evaluated as functions of equivalent stress intensity factor range, strain energy density factor range and crack tip opening displacement vector, respectively. It is shown that the biaxial mode fatigue crack growth rates can be relatively consistently predicted with these cyclic parameters.

• International Journal of Highway Engineering
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• v.17 no.6
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• pp.37-45
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• 2015

PURPOSES : The purpose of this study is to validate the design criteria of the concrete modular road system, which is a new semi-bridge-type concept road, through a comparison of numerical analysis results and actual loading test results under static axial loads. METHODS : To design the semi-bridge-type modular road, both the bridge design code and the concrete structural design code were adopted. The standard truck load (KL-510) was applied as the major traffic vehicle for the design loading condition. The dimension of the modular slab was designed in consideration of self-weight, axial load, environmental load, and combined loads, with ultimate limit state coefficients. The ANSYS APDL (2010) program was used for case studies of center and edge loading, and the analysis results were compared with the actual mock-up test results. RESULTS : A full-scale mock-up test was successfully conducted. The maximum longitudinal steel strains were measured as about 35 and 83.5 micro-strain (within elastic range) at center and edge loading locations, respectively, under a 100 kN dual-wheel loading condition by accelerating pavement tester. CONCLUSIONS : Based on the results of the comparison between the numerical analysis and the full-scale test, the maximum converted stress range at the edge location is 32~51% of the required standard flexural strength under the two times over-weight loading condition. In the case of edge loading, the maximum converted stresses from the Westergaard equation, the ANSYS APDL analysis, and the mock-up test are 1.95, 1.7, and 2.3 times of that of the center loading case, respectively. The primary reason for this difference is related to the assumption of the boundary conditions of the vertical connection between the slab module and the crossbeam module. Even though more research is required to fully define the boundary conditions, the proposed design criteria for the concrete modular road finally seems to be reasonable.

• The Journal of Advanced Prosthodontics
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• v.1 no.3
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• pp.136-139
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• 2009

STATEMENT OF PROBLEM. Many dental clinicians are concerned about immediate loading of inserted implants. However, there have been few clinical studies surveying the success rates of immediate loading, based on Korean implant systems. PURPOSE. The aim of this study was to evaluate the outcome of immediate functional loading of the implant ($SinusQuick^{TM}$EB, Neobiotech Co., Seoul, Korea) in partially edentulous maxilla or mandible. MATERIAL AND METHODS. Total 15 implants were placed. Within 2 weeks after implant insertion, provisional implant-supported fixed partial dentures were delivered to the patients. Quantitatively, marginal bone loss was measured at the time of immediate loading, after 3-months of continued loading and at the last follow-up. The mean follow-up period was 4.8 months. RESULTS. Mean marginal bone loss from implant surgery to early loading, 3-months follow-up and last follow-up was $0.03\pm0.07$ mm, $0.16\pm0.17$ mm and $0.29\pm0.19$ mm. No implant failed up to 6 months after insertion, resulting in a 100% survival rate. CONCLUSION. Immediate loading exhibited high success rate in partial edentulism for up to 6 months. Well-controlled long term clinical studies with large sample size are necessary to confirm this finding.

• Journal of the Korea Institute of Military Science and Technology
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• v.16 no.3
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• pp.382-389
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• 2013

In anti-jamming GPS receiver, adaptive signal processing techniques in which the radiation pattern of adaptive array antenna of elements may be adaptively changed used to reject interference, clutter, and jamming signals. In this paper, I describes adaptive signal processing technique using the sample matrix inversion(SMI) algorithm. This adaptive signal processing technique can be applied effectively to wideband/narrowband anti-jamming GPS receiver because it does not consider the satellite signal directions and GPS signal power level exists below the thermal noise. I also analyzed the effects of covariance matrix sample size and diagonal loading technique on the system performance of five-element circular array antenna. To attain near optimum performance, more samples required for calculation covariance matrix. Diagonal loading technique reduces the system nulling capability against low-power jamming signals, but this technique improves robustness of adaptive array antenna.

• Architectural research
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• v.10 no.1
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• pp.13-23
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• 2008

It is the purpose of this study to evaluate the structural performance of steel pipe splice for SD500 high-strength reinforcing bar, through a cyclic loading test. The experimental variables adopted in this study include the development length of rebar, the type of sleeve, and size of reinforcing bar, among others. The results of this study showed that the developed steel pipe splice system for SD500 high-strength reinforcing bar, retained the structural performance required in domestic, ACI and AIJ code. It is considered that the study result presented in this paper can be helpful in developing a reasonable design method for a steel pipe splice system for SD500 high-strength reinforcing bar.

• Journal of the Korea Society of Computer and Information
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• v.22 no.12
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• pp.131-136
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• 2017

PLM(Product Lifecycle Management) is an information management system that can integrate data, processes, business systems and human resources throughout the enterprise. BOM(Bills Of Material) is key data for designing, purchasing materials, manufacturing planning and management, which is basic for product development throughout the product life cycle. In this paper, we propose the efficient system to increase the data loading speed and the processing speed when using such large BOM data. We present the performance and usability of IMDG (In Memory Data Grid) for data processing when loading large amounts of data. In the UI, using the pure web grid of JavaScript instead of the existing data loading method can be improve performance of data managing.