• The Transactions of The Korean Institute of Electrical Engineers
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• v.64 no.1
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• pp.136-142
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• 2015

In the paper, a design method of knee and pelvis joint in the biped robot is proposed for shock absorption and gravity compensation. Similarly to the human's body, the knee joints of the biped robot support most body weight and get a shock from the landing motion of the foot on the floor. The torque of joint motor is also increased sharply to keep the balance of the robot. Knee and pelvis joints with the spring are designed to compensate the gravity force and reduce the contact shock of the robot. To verify the efficiency of the proposed design method, we develope a biped robot with the joint mechanism using springs. At first, we experiment with the developed robot on the static motions such as the bent-knee posture both without load and with load on the flat ground, and the balance posture on the incline plane. The current of knee joint is measured to analyze the impact force and energy consumption of the joint motors. Also, we observe the motor current of knee and pelvis joints for the walking motion of the biped robot. The current responses of joint motors show that the proposed method has an effect on shock reduction and gravity compensation, and improve the energy efficiency of walking motions for the biped robot.

• Journal of Microbiology
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• v.39 no.1
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• pp.67-73
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• 2001

A validation study was conducted to evaluate the efficacy and mechanism of the cryo-precipitation, monoclonal anti-FVIIIc antibody (mAb) chromatography, Q-Sepharose chromatography, and lyophilization steps involved in the manufacture of high purity factor VIII (GreenMono) from human plasma, in the removal and/or inactivation of hepatitis A virus (HAV). Samples from the relevant stages of the production process were spiked with HAV and subjected to scale-down processes mimicking the manufacture of the high purity factor VIII concentrate. Samples were collected at each step and immediately titrated using a 50% tissue culture infectious dose (TCID$\_$50/) and then the virus reduction factors were evaluated. HAV was effectively partitioned from factor VⅢ during cryo-precipitation with the log reduction factor of 3.2. The mAb chromatography was the most effective step far removal of HAV with the log reduction factor of $\geq$4.3. HAV infectivity was not detected in the fraction of factor VⅢ, while most of HAV infectivity was recovered in the fractions of flow through and wash during mAb chromatography. Q-Sepharose chromatography showed the lowest efficacy for partitioning HAV with the log reduction factor of 0.7. Lyophilization was an effective step in inactivating HAV with the log reduction factor of 2.3. The cumulative lag reduction factor, $\geq$10.5, achieved for tile entire manufacturing process was several magnitudes greater than the potential HAV load of current plasma pools.

• Journal of the Korean Geotechnical Society
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• v.32 no.12
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• pp.79-91
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• 2016

Geosynthetic-reinforced and Pile-supported (GRPS) embankment method is widely used to construct structures on soft ground due to restraining residual settlement and their rapid construction. However, effect of cyclic loading has not been established although some countries suggest design methods through many studies. In this paper, cyclic loading tests were conducted to analyze dynamic load transfer characteristics of pile-supported embankment reinforced with geosynthetics. A series of 3 case full scale model tests which were non-reinforced, one-layer-reinforced, two-layer reinforced with geosynthetics were performed on piled embankments. In these series of tests, the height of embankment and pile spacing were selected according to EBGEO (2010) standard in Germany. As a result of the vertical load parts on the pile and on the geosynthetic reinforcement measured separately, cyclic loads transferred by only arching effect decreased with strength geosynthetic-reinforced case. However, final loads on the pile showed no differences among the cases. These results conflict with previous studies that reinforcement with geosynthetics increases transfer load concentrated on piles. In addition, it is observed that the load transferred to pile decreases at the beginning of cycle number due to reduction of arching effected by cyclic loading. Based on these results, transferred mechanism for cyclic load on GRPS system has been presented.

• Proceedings of the Korean Geotechical Society Conference
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• 2008.03a
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• pp.1240-1249
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• 2008

Jacket anchor was developed to increase the pullout resistance of general ground anchor in soft ground, and the mechanism of pullout resistance of jacket anchor was analyzed. Also, the ultimate bond stress of jacket anchor was estimated by ultimate resistance which is determined by field tests. Grout milk was injected into the jacket to make grout bulb of jacket anchor. The formation of grout bulb of jacket anchor increases the diameter of grout bulb, ground strength and confining pressure between anchor grout and soil. From the twelve field test results, it was observed that the pullout resistance of jacket anchor is 15.38~295.02%(average 83.53%) greater than that of general ground anchor, and plastic deformation of jacket anchor is 20.78~1,496.45%(average 288.78%) smaller than that of general ground anchor at the same load cycle. Especially, it was investigated that the increase of ultimate resistance over 200% and the reduction of plastic deformation over 600% was obtained in gravel layer. It means that the jacket anchor is superior to the general ground anchor in gravel layer. Finally, the ultimate bond stress was proposed to design jacket anchor.

• Journal of Ocean Engineering and Technology
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• v.12 no.3 s.29
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• pp.49-59
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• 1998

The damage mechanism of $Cr_2O_3$ plasma coated soda-lime glass and uncoated glass by steel ball particle impact was analyzed in this study. And the shape variation of the cracks was investigated by stereo-microscope according to the impact velocity and steel ball diameter. In order to improve the damage reduction effect by $Cr_2O_3$ coating layer, crack size was measured and surface erosion state was observed for both of two kinds of specimen after impact experiment. And the results were compared with each other. The 4-point bending test was performed according to ASTM D790 testing method to evaluate the effect of coating layer for bending strength variation. As a result, it was found that the crack size of $Cr_2O_3$ coated specimen was smaller than that of uncoated one, because of the impact absorption by interior pores in the coating layer and the load dispersion by the structural characteristic of the coating layer. For the specimens subjected to the steel ball impact, the bending strength of coated specimen was higher than that of uncoated specimen.

• Advances in concrete construction
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• v.9 no.6
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• pp.597-610
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• 2020

Stress-strain models of fibre reinforced polymer (FRP) confined concrete have been widely investigated; however, the existing load which is always supported by structures during the retrofitting phase, namely 'preload', has been neglected. Thus, preload effects should be clarified, providing insightful information for FRP retrofitting of structures with preload conditions. Towards this aim, experiments were performed for 27 cylinder concrete specimens with the diameter 150 mm and the height 300 mm. Three specimens were used to test the compressive strength of concrete to compute the preloads 20%, 30% and 40% of the average strength of these specimens. Other 24 specimens were divided into 2 groups; each group included 4 subgroups. Four subgroups were subjected to the above preloads and no preload, and were then wrapped by 2 FRP layers. Similar designation is applied to group 2, but wrapped by 3 FRP layers. All specimens were tested under axial compression to failure. Explosive failure is found to be the characteristic of specimens wrapped by FRP. Experimental results indicated that the preload decreases 12-13% the elastic and second stiffness of concrete specimens wrapped by 2 FRP layers. The stiffness reduction can be mitigated by the increase of FRP layers. Preload negligibly reduces the ultimate force and unclearly affects the ultimate displacement probably due to complicated cracks developed in concrete. A mechanism of preload effects is presented in the paper. Finally, to take into account preload effects, a modification of the widely used model of un-preload FRP confined concrete is proposed and the modified model demonstrated with a reasonable accuracy.

• Preventive Nutrition and Food Science
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• v.3 no.1
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• pp.48-55
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• 1998

An acute ethanol load(50mmol/kg , i.p) resulted in an increase in peroxidation and a decrease in the levels of $\alpha$-tocopherol and ascorbate in rat cerebellum. Pretreatement with allopurinol(146$\mu$mol/kg, i.p) prevented the ethnol-induced increment in lipid peroxidation and decrease in $\alpha$-tocopherol content. However, the decrease of ascorbate was of greater magnitude when allopurinol was associated with ethanol. These results suggested that allopurinol. besides its action as a radical scavenger and xanthine oxidase inhibitor, might favor the regeneration of $\alpha$-tocopherol antioxidant acitviity was studied using ${\gamma}$-radiolysis in aerated ethanolic solutions. Even though allopurinol did not react by itself with $\alpha$-hydroxyethyl-peroxyl radicals [H3C-CH(OH)OO] , it enhance the $\alpha$-hydroxyethyl-peroxyl radical scavenging properties of $\alpha$tocopherol. The regeneration of $\alpha$-tocopherol from the $\alpha$-hydroxyethyl-peroxyl radical scavenging properties of $\alpha$-tocophero. The regeneration of $\alpha$-tocopherol from the $\alpha$-tocopherol radical by ascorbate remained as efficient in the presence of allopurinol as in its absence. The effects of allopurinol on the Vitamin E oxidation-reduction mechanism could be involoved in the beneficial effectof allopurinol on the biological cellular damages linked to free radical reactions.

• The Korean Journal of Physiology and Pharmacology
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• v.11 no.6
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• pp.253-257
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• 2007

Among the arthritis symptoms, chronic pain is the most serious, and it can profoundly affect the quality of human life. Unfortunately, the mechanism of development in arthritis and arthritic pain has not yet been precisely elucidated. Accumulating evidence indicates that nitric oxide (NO) plays a pivotal role in nociceptive processing in the spinal cord. However, the modulation mechanism of NO in the peripheral site of arthritis and arthritic pain has not been clarified. Therefore, I determined in the present study which nitric oxide synthase (NOS) was involved in the induction of arthritis and arthritic pain. Monoarthritis was induced by intra-articular injection of carrageenan (2%, $50{\mu}l$) into rats, and resulted in the reduction of weight load on the injected leg, increase of knee joint diameter and inflammatory response. Pre-treatment of rats with L-N6-(1-iminoethyl)-lysine (L-NIL, $500{\mu}g$, in $50{\mu}l$), an inhibitor of inducible NOS (iNOS), partially prevented the induction of pain-related behavior and partially reduced inflammatory response in the synovial membrane in the knee joint. These results suggest that iNOS in the knee joint may play an important role in the induction of pain-related behavior and inflammation, and that NO produced by iNOS may be associated with nociceptive signaling in the peripheral site.

• Proceedings of the Korean Society for Agricultural Machinery Conference
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• 2000.11b
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• pp.162-169
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• 2000

This study was carried out to develop a continuously variable-speed transmission(CVT) for agricultural tractor. A full-toroidal CVT mechanism with four discs and six rollers was selected as a device for changing speed ratio continuously. In the step of system layout design, the sizes of roller cylinders and end-load cylinder, which were critical factors for controlling the variator, were designed. Also the control pressure range was designed to limit the contact pressure of variator. In order to make the maximum speed of vehicle as 30km/h, the planetary gear and the six pairs of gears were designed. Also the hydraulic clutch, silent chain, hydraulic manifold and electronic controller were designed. After the design, a prototype with CVT controller was developed and tested. The speed of vehicle was changed continuously to the speed set by driver and the settling time was about 0.52 second at the step-response test (reduction ratio of variator 2.0 to 1.0), which was acceptable as a response time for working with tractor.

• Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference
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• 2002.10b
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• pp.89-90
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• 2002

Ball reducer (HERB Drive: High Efficient Wave Rolling Ball Drive) with waved grooves has many advantages over other types of reducers for high-reduction ratio, low noise and low energy loss, etc. The mechanism of force transmission is very similar to that of cam and follower in automobile valve train system especially in contact behaviors. In this study, we have investigated the traces of contact between ball and outer ring, and the dynamic contact behaviors of elastohydodynamic lubrication(EHL) with a certain reduction ratio. In order to verify the contact behaviors between ball and outer ring for the critical endurance lift, the contact velocity and load are computed for a cycle. During some intervals of a cycle, the contact velocity reverses its direction very suddenly. It is expected that changing the contact direction causes undesirable endurance performance because EHL film frequently col lapse at the moment of velocity reversal. From the computational investigation in this work, we hope to predict similar contact damages in other machinery due to this kind of contact behaviors, which is very typical in many contact phenomena.