• 제목/요약/키워드: Living Factor

검색결과 1,793건 처리시간 0.027초

Analysis of Pregnancy-Associated Plasma Protein-A (PAPP-A) in Porcine Neonatal Testis (미성숙 돼지 정소 내에서의 pregnancy-associated plasma protein-A 특성 분석)

  • Lee, W.Y.;Cho, K.H.;Yeo, J.M.;Shin, Y.K.;Park, J.K.
    • Journal of Practical Agriculture & Fisheries Research
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    • 제22권1호
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    • pp.5-13
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    • 2020
  • The identify of biomarkers in living tissues is useful to understand the characteristics and functions of the cells. Proteins such as protein gene product 9.5, promyelocytic leukemia zinc finger, NANOG, and stage-specific embryonic antigen-1 have been identified as markers for porcine undifferentiated spermatogonia. In this study, the expression of insulin-like growth factor binding proteins (IGFBPs), a newly discovered porcine spermatogonia marker and pregnancy-associated plasma protein-A (PAPP-A), a protein regulator of IGFBPs, were characterized in 5-day-old porcine testis. To analyze the function of IGFBPs, RT-PCR was performed. IGFBP 2, 3, 4, and 6 were detected in porcine spermatogonia and PAPP-A was detected in basement regions in 5day old porcine seminiferous tubules. PAPP-A was not expressed in spermatogonia, but it was expressed in Sertoli cells. These results suggest that the expression of PAPP-A protein in Sertoli cells may regulate the development and differentiation of testicular cells through the IGF axis in porcine neonatal testis.

Interpretive Approaches to the Characteristics of Neighborhood Environment Using Qualitative GIS of the Elderly's Outdoor Activities - Focused on the Musugol, a Low-Income Elderly Concentrated Area in Seoul - (노인층 옥외활동의 질적 GIS를 활용한 근린환경 특성의 해석 - 서울시 저소득 노인밀집지역 무수골을 대상으로 -)

  • Yun, Ye-Hwa;Sung, Jong-Sang
    • Journal of the Korean Institute of Landscape Architecture
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    • 제50권3호
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    • pp.1-18
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    • 2022
  • Prior studies have shown positive effects of outdoor activities on the elderly's physical, mental and social health. 'Active aging' and 'age-friendly' neighborhood can be created by modifying the experiences and perceptions of the outdoor environment. This study aims to investigate the outdoor activities of the elderly living in a low-income elderly concentrated area and their perception of the neighborhood environment. We also explored the context of interactions between the facilitators and inhibitors of outdoor activities on the basis of temporal, spatial, and social conditions. We used a mixed method approach by collecting two different types of qualitative GIS data : observation maps of the main places and individual cognitive maps with in-depth interviews. The observational map analysis indicated that the preferred places and activity patterns differ by age, gender, and size of the group. The cognitive map and interviews demonstrated that the elderly's activity goals and perception of the landscape differ by places such as forests, parks, streams, open-spaces, vegetable gardens, and alleys. The elderly's desire for outdoor activities can be better fulfilled when their front doors and alleys are well-connected to an open-sight pleasant space. Familiarity is an important factor for the elderly, therefore it is important to remove the psychological and physical barriers by increasing the legibility and accessibility of places. In addition, social interactions and conflicts can have a significant influence on the elderly's occupation of space in the neighborhood environment.

The Relationship among Leisure Experience, Exercise flow Adherence of Senior in Fitness Center (스포츠센터 노인 운동 프로그램 참여자의 여가경험과 여가몰입 및 운동만족의 관계)

  • Lee, Seung-Bum
    • Journal of Korea Entertainment Industry Association
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    • 제15권2호
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    • pp.159-167
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    • 2021
  • The main purpose of this study is to closely investigate the constructive relationship between leisure satisfaction, leisure ability, exercise satisfaction, and consistent motor behavior patterns of the elderly's participation in leisure life sports. In order to achieve this, we surveyed and utilized the sampling of conveniences that selected Yongin and Seongnam city in Gyeonggi-do sports clubs, and accumulated samples of the elderly in living sports. The sample size was 239 elderly people. Based on this, according to the purpose of the study, statistical techniques, spss 23.0, and amos programs were used for analysis. The satisfaction analysis used in the research for a data analysis includes frequency analysis, exploatory factor analysis, confirmatory facor analysis, reliability analysis, correnlation analysis and structure equation model analysis. The research has drawn the following conclusions, based on the above mentioned research method and its procedures: First, it affects the satisfaction of the leisure satisfaction movement. Second, leisure ability affects exercise satisfaction. Third, exercise satisfaction affects the consistent exercise persistence and immersion satisfaction of exercise. As a result, it can be seen that the leisure immersion according to the experience of leisure competence has an effect on the satisfaction of the exercise. As a result, and the continuation of the exercise.

A Study on the Gap Analysis of Public Libraries in Gyeongbuk Region (경북지역 공공도서관 격차분석 연구)

  • Yoon, Hee-Yoon
    • Journal of the Korean Society for Library and Information Science
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    • 제56권1호
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    • pp.5-25
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    • 2022
  • In most countries, public libraries are knowledge information centers, complex cultural spaces, lifelong learning facilities, and third places for local residents. The social homage spoken on the premise of this identity and socio-cultural role is the knowledge and information agora, cultural infrastructure, living room in the city, and the university of the people. However, if there is a significant gap between public libraries regardless of country or region, it will inevitably lead to information gaps, regional gaps, and cultural inequality and cultural welfare gaps among local residents. This study is regarded as the essence of regional cultural facilities and premised that the regional gap in public libraries is a factor of regional cultural gaps. Based on this premise, the gap between the location quotient, input indicators, and output indicators of public libraries of regional governments in Korea and basic local governments in the Gyeongbuk region was analyzed. And this study derived core elements through correlation and regression analysis of input and output indicators of all public libraries nationwide, developed a management model for each indicator, and suggested a plan to resolve the relative gap for public libraries by city and county in Gyeongbuk.

Effects of lifestyle on dry mouth and dry eyes

  • Jung, Yu Yeon
    • Journal of the Korea Society of Computer and Information
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    • 제27권12호
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    • pp.259-266
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    • 2022
  • In this paper, we propose a study is to prepare basic data for integrated health promotion education by preventing dry mouth and dry eyes through lifestyle management. From October 7 to 17, 2022, a total of 516 respondents who voluntarily agreed and responded through a self-written structured questionnaire were statistically analyzed for university students in their 20s across the country. As for the factor of feeling dry mouth among the living habits of the study subjects, the more smoking per day, the higher(8.41±2.041) and very high(7.75±2.927) felt dry mouth(p=.015), and the time spent using smart phones. The shorter this was, the lower(1.16±0.784) and very low(1.83±1.672) felt dry mouth(p=.022). The main factors contributing to dry mouth and dry eyes were dry eyes (odds ratio 3.651, p=.000), and high smoking(odds ratio 0.916, p=.038), and the more you use your smart phone (odds ratio 0.256, p=.004), the more you feel dry mouth. When feeling dry eyes, they felt dry mouth more(odds ratio 4.002, p=.000), and the more they exercised, the more dry eyes they felt(odds ratio 1.600, p=.009). As a result, since dry mouth and dry eyes appear as common inconveniences, it was found that lifestyle management is necessary to maintain and promote a healthy life. Therefore, it is proposed to build an integrated health platform that can improve the quality of life and implement personalized health management programs.

Analysis of Threat Factors of the Chinese Maritime Militia and the Prospect of Maritime Disputes between Korea and China (중국 해상 민병대의 위협요인 분석 및 한·중 해양 분쟁 전망)

  • Park, Byeung chan
    • Maritime Security
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    • 제4권1호
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    • pp.83-113
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    • 2022
  • Although China's maritime militia has not been well known despite its long history, it is recently emerging as a serious threat to maritime security, causing neighboring countries' security concerns due to the growing number of maritime disputes with China. In this regard, it is now time to clearly define the true nature of the Chinese maritime militia. A close look at the organization and roles of the Chinese maritime militia reveals that it is an organization that is systematically managed and operated by the Chinese government and the People's Liberation Army of China. Its role is to serve the purpose of "contributing to the protection and expansion of China's marine interests." In addition, the threat factors of the Chinese maritime militia were analyzed by examining the cases of maritime disputes between the Chinese maritime militia and neighboring countries. First, the Chinese maritime militia has implemented the "Gray Zone Strategy." Second, it is a systematic organization supported by the Chinese government and the People's Liberation Army. Third, it is a maritime power that cannot be ignored as the world's largest militia organization. Fourth, it has a strategic flexibility that enables the execution of the dual mission of working for a living such as commercial fishing and serving in the maritime militia. The threats of the Chinese maritime militia are not limited to Southeast Asian countries located in the South China Sea. This is also the case in Korea as the country cannot avoid maritime disputes with China such as the Ieodo issue and the boundary delimitation of the West Sea. Accordingly, this study was focused on presenting a predictable scenario and countermeasures based on the analysis through a scenario technique with respect to the two cases that are most likely to occur in Korea-China relations. Finally, beyond identifying the nature of the Chinese maritime militia, this study takes a further step to share considerations as to how the organization may operate and develop in the future and how we can cope with its moves.

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Clinical Outcomes and Contributors in Contemporary Kidney Transplantation: Single Center Experience (근래의 신장이식 임상성적과 관련인자들: 단일기관 연구)

  • Ahn, Jae-Sung;Park, Kyung Sun;Park, Jongha;Chung, Hyun Chul;Park, Hojong;Park, Sang Jun;Cho, Hong Rae;Lee, Jong Soo
    • Korean Journal of Transplantation
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    • 제31권4호
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    • pp.182-192
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    • 2017
  • Background: In recent years, introduction of novel immunosuppressive agents and its proper implementation for clinical practice have contributed to improving clinical outcomes of kidney transplantation (KT). Here, we report clinical outcomes of KTs and related risk factors. Methods: From July 1998 to June 2016, 354 KTs (182 from living and 172 from deceased donors) have been performed at Ulsan University Hospital. We retrospectively reviewed the clinical characteristics and outcomes of KT recipients, then estimated graft and patient survival rate were estimated and analyzed risk factors using Cox-regression. Results: The median follow-up period was 53 months (range; 3 to 220 months). The mean ages of recipients and donors were 45.0 years (SD, 12.5) and 44.7 years (SD, 13.6) years, respectively. During follow-up, 18 grafts were lost and 5- and 10-year death-censored graft survival was 96.7% and 91.5%, respectively. Biopsy-proven acute rejection (BPAR) occurred in 71 patients (55 cases of acute cellular rejection and 16 of antibody-mediated rejection). Cox-regression analysis showed that BPAR was a risk factor related to graft loss (hazard ratio [HR], 14.38; 95% confidence interval [CI], 3.79 to 54.53; P<0.001). In addition, 15 patients died, and the 5- and 10-year patient survival was 97.2% and 91.9%, respectively. Age ≥60 years (HR, 6.03; 95% CI, 1.12 to 32.61; P=0.037) and diabetes (HR, 6.18; 95% CI, 1.35 to 28.22; P=0.019) were significantly related to patient survival. Conclusions: We experienced excellent clinical outcomes of KT in terms of graft failure and patient survival despite the relatively high proportion of deceased donors. Long-term and short-term clinical outcomes have improved in the last two decades.

The Effect of Stress Response in Middle Age on Psychological Fertility Positive, Automated Thinking Mediating Effects (중년기 스트레스 대처가 심리적 안녕감에 미치는 영향 긍정적 자동적 사고 매개 효과)

  • Yoon Ju Jung
    • Industry Promotion Research
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    • 제8권2호
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    • pp.133-140
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    • 2023
  • The purpose of the study is to verify the mediating effect of positive automatic thinking in the relationship between stress coping and psychological well-being in middle age. For this study, a survey was conducted on middle-aged people under the age of 40 to 65 living in Seoul, Gyeonggi-do, and Incheon. A total of 200 questionnaires were distributed from March 9 to March 27, 2023, and 187 questionnaires were used for the final analysis, except for 13 copies whose responses were judged to be poor or unreliable. Correlation, factor analysis, and structural equation models were conducted, and bootstrapping was analyzed to verify the mediating effect. As a result of the analysis, it was confirmed that coping with stress in middle age affects psychological well-being. As a result of analyzing the influence of problem-solving-oriented, social support-oriented, and avoidance-oriented as sub-factors of coping with stress, it was found to have a significant effect on psychological well-being. Stress coping has been shown to have a direct effect on psychological well-being and increase psychological well-being through the parameters of positive automatic thinking. consequently within the individual of coping with stress in middle age.It is expected that the buffering effect of external factors and positive automatic thinking will improve psychological well-being in middle age and achieve positive results.

A Study on the Intention to Use of the AI-related Educational Content Recommendation System in the University Library: Focusing on the Perceptions of University Students and Librarians (대학도서관 인공지능 관련 교육콘텐츠 추천 시스템 사용의도에 관한 연구 - 대학생과 사서의 인식을 중심으로 -)

  • Kim, Seonghun;Park, Sion;Parkk, Jiwon;Oh, Youjin
    • Journal of Korean Library and Information Science Society
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    • 제53권1호
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    • pp.231-263
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    • 2022
  • The understanding and capability to utilize artificial intelligence (AI) incorporated technology has become a required basic skillset for the people living in today's information age, and various members of the university have also increasingly become aware of the need for AI education. Amidst such shifting societal demands, both domestic and international university libraries have recognized the users' need for educational content centered on AI, but a user-centered service that aims to provide personalized recommendations of digital AI educational content is yet to become available. It is critical while the demand for AI education amongst university students is progressively growing that university libraries acquire a clear understanding of user intention towards an AI educational content recommender system and the potential factors contributing to its success. This study intended to ascertain the factors affecting acceptance of such system, using the Extended Technology Acceptance Model with added variables - innovativeness, self-efficacy, social influence, system quality and task-technology fit - in addition to perceived usefulness, perceived ease of use, and intention to use. Quantitative research was conducted via online research surveys for university students, and quantitative research was conducted through written interviews of university librarians. Results show that all groups, regardless of gender, year, or major, have the intention to use the AI-related Educational Content Recommendation System, with the task suitability factor being the most dominant variant to affect use intention. University librarians have also expressed agreement about the necessity of the recommendation system, and presented budget and content quality issues as realistic restrictions of the aforementioned system.

Elderly Sarcopenia and Vitamin B Deficiency: A Relationship? (비타민 B 결핍에 의한 노인성 근감소증)

  • Kisang Kwon;Hye-Jeong Jang;Sun-Nyoung Yu;Soon-Cheol Ahn;O-Yu Kwon
    • Journal of Life Science
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    • 제33권7호
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    • pp.574-585
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    • 2023
  • Sarcopenia is a leading cause of increased medical and nursing care costs among the elderly. In Korea, preventive measures for sarcopenia are mostly targeted toward the general elderly population without specific diseases. However, it is also necessary to implement measures for elderly individuals living in nursing homes and hospitals, where the prevalence of sarcopenia is high. Currently, computed tomography and/or magnetic resonance imaging are considered standard diagnostic tools. However, their complexity and time-consuming nature make them unsuitable for clinical use. The exact pathophysiological mechanisms of sarcopenia are unclear, as they involve various molecular biological pathways, including decreased exercise, protein and nutrient intake, changes in testosterone and growth hormone, and inflammation. Sarcopenia symptoms can lead to several diseases, such as osteoporosis, fractures, dementia, diabetes, and cardiovascular disease. Vitamin B deficiency is a significant factor in sarcopenia induction, with B vitamins being directly involved in energy and protein metabolism and nerve function. Vitamin B deficiency can lead to neuromuscular and neurogenic disorders, which often overlap with sarcopenia. Suboptimal intake of B vitamins, malabsorption, and anorexia are common among the elderly. This study aims to provide information on the role of water-soluble B vitamins in preventing and controlling muscle mass loss and deterioration among the elderly with sarcopenia. In addition, we discuss the potential of myokines from the B vitamin family in modulating sarcopenia.