• Title/Summary/Keyword: Linolenic and

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Effect of Dietary Oil Containing $\gamma$-Linolenic Acid on the Plasma Lipid Levels and Thrombotic Activity in Rats (감마-리놀렌산을 함유하는 식이지방이 흰쥐의 혈전작용 및 혈액지질 수준에 미치는 영향)

  • ;Zammit, A Victor
    • Journal of Nutrition and Health
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    • v.36 no.9
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    • pp.889-897
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    • 2003
  • This study was carried out to determine the effect of dietary ${\gamma}$-linolenic acid on decreasing the plasma lipid levels and the thrombotic activity in rats. Sprague-Dawley male rats (B.W 120 g) were fed a experimental diet containing 5% lard (46.05% saturated fatty acids) , corn oil (51.36% linoleic acid) , evening primrose oil (EPO,72.80% linoleic acid and 9.16% ${\gamma}$-linolenic acid) or borage oil (BO,40.29% linoleic acid and 24.25% ${\gamma}$-liolenic acid) for 30 days. Although there were no significant differences in the food intake among the groups, the body weight gain of the BO group was significantly lower than that of the other groups. The bleeding time of the BO group was significantly longer than that of the other groups. There were significantly differences in the whole blood clotting time among the groups except for the EPO and corn oil groups, where the whole blood clotting time of the BO group was the highest among the groups, and that of the lard group was the lowest. The plasma triacyglyceride (TAG) , total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) concentrations were the lowest in the BO group, but highest in the lard group, and there were significant differences among the groups. The plasma HDL-C concentrations were in the following order: BO, EPO, corn oil and lard groups and there were significant differences among the groups. The excretions of fecal neutial steroids and acidic steroids of the BO group were the highest among the groups, and there were significant differences compared to the other groups. The results suggest that dietary EPO and BO containing ${\gamma}$-linolenic acid has an antithrombotic activity, and inhibits the increasing of plasma TAG, TC and LDL-C concentrations compared to lard, which contains saturated fatty acids, or corn oil, which contains linoleic acid.

Effects of α-Linolenic, Eicosapentaenoic and Docosahexaenoic Acids on the Content and Fatty Acid Composition of Brain Phospholipid in Rats

  • Cha, Jae-Young;Cho, Young-Su
    • Journal of Applied Biological Chemistry
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    • v.42 no.2
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    • pp.75-80
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    • 1999
  • The effects of dietary n-3 fatty acids, ${\alpha}$-linolenic acid (18:3), eicosapentaenoic acid (EPA, 20:5), and docosahexaenoic acid (DHA, 22:6), on brain phospholipid content and fatty acid composition were compared in rats fed with a diet containing constant ratios of saturated fatty acid/monounsaturated fatty acid/polyunsaturated fatty acid (PUFA) and n-3/n-6. The dietary fat in each diet was added at the level of 10%. In each diet, n-3 PUFA comprised two-thirds of the PUFA and the remaining one-third was linoleic acid (18:2). Dietary fat containing linoleic acid as the sole source of PUFA was also given to the control group. The content of brain phospholipid in the three n-3 PUFA groups was significantly lower than that of the linoleic acid group. This reduction was greater in the EPA and DHA groups than in the ${\alpha}$-linolenic acid group. The decrease in phospholipid content in rats fed n-3 fatty acid-rich diets was largely due to the decrease in the phosphatidylethanolamine fraction. Each dietary n-3 PUFA was found to affect the fatty acid composition of brain phospholipids; the most pronounced alteration was observed in phosphatidylethanolamine fraction. Furthermore, the proportion of DHA in the phosphatidylethanolamine fraction tended to be higher in the DHA group than in other PUFA groups. In conclusion, dietary ${\alpha}$-linolenic acid, EPA and DHA can influence the phospholipid content, phospholipid subclass, and fatty acid composition in rat brain.

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Seed Protein Content and Fatty Acid Composition of Black Seeded Soybeans Collected From Southwestern Islands (서남해안 검정콩들의 단백질과 지방산 조성변이)

  • 권병선;신정식
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.47 no.3
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    • pp.240-243
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    • 2002
  • A total of 135 black seeded soybeans genotypes were collected in 45 island locations from January to May 2001. Seeds of 135 genotypes collected were analyzed for crude protein and fatty acid compositions. The crude protein content was averaged to be 40.75%, and was ranged from 34.70% to 44.20%. The average palmitic acid, stearic acid, oleic acid, linoleic acid and linolenic acid content were 11.41%, 3.93%, 22.75%, 53.55%, and 8.35%, and the ranges of those were 9.00% to 14.40%, 2.90% to 5.00%, 22.75% to 26.50%, 50.30% to 57.20% and 6.7% to 11.20%, respectively. Heritabilities of palmitic acid, oleic acid, linoleic acid, and crude protein were higher, but that of stearic acid and linolenic acid were relatively lower, Crude protein content was correlated positively with oleic acid content, whereas it was correlated negatively with linoleic acid, palmitic acid, stearic acid, and linolenic acid contents.

Screening of ${\gamma}-linolenic$ Acid Resources and Fatty Acid Composition in Korean Native Medicinal Plants Resources (국내 약용자원식물의 지방산 조성과 ${\gamma}-linolenic$ acid 탐색)

  • Kim, Jung-Bong;Kim, Young-Hwan;Lee, Cheol-Hee;Hwang, Young-Soo;Park, Ro-Dong
    • Korean Journal of Medicinal Crop Science
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    • v.3 no.2
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    • pp.107-110
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    • 1995
  • Fatty acid composition analysis was carried out from 60 species of Korean native medicinal plant to screen ${\gamma}-linolenic$ acid(GLA) resources. Oenothera odorata, SymPhytum officinal, and Lithospermum erythrorhizon contained ${\gamma}-linolenic$ acid with 9.5%, 3.5%, 7.2% of total fatty acid content, respectively. The vegetative organs usually contained higher level of ${\alpha}-linolenic$ acid than seeds. Some plants were found to be excellent source of unsaturated fatty acid.

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A Kinetic Study of Fatty Acid Composition of Embryos, Oviductal and Uterine Fluids in the Rabbit

  • Yahia Khandoker, M.A.M.;Tsujii, H.;Karasawa, D.
    • Asian-Australasian Journal of Animal Sciences
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    • v.11 no.1
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    • pp.60-64
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    • 1998
  • The different developmental stage embryos and oviductal and uterine fluids of rabbit were analyzed by gas chromatography. Myristic (C 14:0), palmitic (C 16:0), palmitoleic (C 16:1), stearic (C 18:0), oleic (C 18:1), linoleic (C 18:2), linolenic (C 18:3), arachidic (C 20:0), arachidonic (C 20:4), docosahexaenoic (C 22:6) and lignoceric (C 24:0) acids were the common fatty acid constituents with little exception. In most of the samples palmitic, oleic, linoleic and arachidonic acids were observed in high concentration. Moreover, linoleic, linolenic and arachidonic acids were the three poly-unsaturated fatty acids in both type sample except day-1 oviductal fluids. Similarly, in both day-1 and day-2 oviductal and uterine fluids myristic, palmitoleic, stearic, linolenic, arachidic and docosahexaenoic acids were in less composition or undetected.

Study on the Oxidative Stability of Korean Evening Primrose Oil (한국산 달맞이꽃 종자유의 산화안정성에 관한 연구)

  • 표영희;김인숙;안명수
    • Korean journal of food and cookery science
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    • v.5 no.2
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    • pp.27-34
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    • 1989
  • In the present study, the oxidative stability of Korean evening primrose oil (EPO) stored in various conditions, i.e., dark, cool, fluorescent light and daylight irradiation were investigated. Furthermore difference between the compositional content of gamma-linolenic acid (GLA) of EPO and that of alpha-linolenic acid of soybean oil (SOY) undergoing various modes of oxidation was observed. The results of the present study were as follows: More rapid autoxidative reations of EPO than that of SOY in vairous conditions increased in order of daylight, fluorescent light, cool and dark. Espectially, autoxidative rates of EPO increased rapidly on exposure to daylight and fluorescent light. This probably was due to chlorophyll functioned as a photosensitizer resulting in rapid oxidation of the EPO during irrdadiation of light. However, there was no difference between compositional content of GLA in EPO and alpha-linolenic acid in SOY undergoing various modes of oxidation. Therefore, theripid oxidative rate of EPO could be due to the catalytic effect of the chlorophyll on the photoxidation and the free radical reaction of PUFA.

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In vitro control of plant pathogens by using anti-fungal hydroxy fatty acid obtained from microbial bioconversion of linolenic acid

  • Kang, Sun-Chul;Bajpai, Vivek K.;Kim, Hak-Ryul
    • 한국생물공학회:학술대회논문집
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    • 2005.04a
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    • pp.309-310
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    • 2005
  • Bioconverted linolenic acid (bLNA) obtained from linolenic acid by Pseudomonas aeruginosa PR3, showed anti-fungal activity against plant pathogens such as B. cinerea, F. oxysporum, F. solani, P. capsici and C. capsici. The oil sample also showed anti-fungal activity with MIC values, ranging from >250 to >1,000 ${\mu}g/ml$. Varied concentrations of bLNA had a great potential effect on spore germination of different fungi.

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Studies on Fungal Lipids Containing ${\gamma}$-Linolenic Acid 1. Fatty Acid Composition of Mucor sp. (${\gamma}$-Linolenic acid 함유 곰팡이 지질에 관한 연구 1. Mucor sp.의 지방산 조성)

  • 송권섭;김충기;권용주;양희천;이태규
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.19 no.6
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    • pp.636-640
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    • 1990
  • For a studyon the production of ${\gamma}$-linolenic acid(GLA) by fungi 3 fungal strains were isolated from soil. Their cell growth lipid content and fatty acid composition were compared in shake flask culture. Among these fungi the fungus designated as FA-007 has high lipid content(21.1%) and GLA content(15.6% of total fatty acids) The fungal strain FA-007 was tentatively identified as Mucor sp. on the basis of morphological characteristics, Fungal oil produced by this fungus was composed of 75.2% neutral lipid 5.3% glycolipid and 19.5% phospholipid. Although the GLA content in phospholipid was higher than it in neutral lipid the GLA content in neurtal lipid was high as 15.5%.

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Elicitors for the Regulation of baccatin III Biosynthesis in Plant Cell Culture System (Elicitor에 의한 baccatin III의 세포내 생합성 조절연구)

  • Shin, Seung-Won;Kim, You-Sun;Lim, Sook
    • YAKHAK HOEJI
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    • v.44 no.1
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    • pp.60-65
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    • 2000
  • The yeast extract, coconut water, safflower seed oil, arachidonic acid, linolenic acid, jasmonic acid and methyl jasmonate were added to Gamborg's B$_{5}$ medium. The changes on productivity of baccatin III were estimated every 30 minutes and the results were compared using the selected high yielding cell culture system of Taxus cuspidata. In most cases, the peaks of baccatin III productivity occured at 90~120 min after addition of elicitors. Among the compound elicitors, safflower seed oil showed the highest productivity of baccatin III. Also arachidonic acid and linolenic acid increased the baccatin III production.

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