• Title/Summary/Keyword: Linkage

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Gamma Mixed Model to Improve Sib-Pair Linkage Analysis (감마 혼합 모형을 통한 반복 측정된 형제 쌍 연관 분석 사례연구)

  • Kim, Jeonghwan;Suh, Young Ju;Won, Sungho;Nah, Jeung Weon;Lee, Woojoo
    • The Korean Journal of Applied Statistics
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    • v.28 no.2
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    • pp.221-230
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    • 2015
  • Traditionally, sib-pair linkage analysis with repeated measures has employed linear mixed models, but it suffers from the lack of power to find genetic marker loci associated with a phenotype of interest. In this paper, we use a gamma mixed model to improve sib-pair linkage analysis and compare it with a linear mixed model in terms of power and Type I error. We illustrate that the use of gamma mixed model can achieve higher power than linear mixed model with Genetic Analysis Workshop 13 data.

Prospects of Application of Linkage Disequilibrium Mapping for Crop Improvement in Wild Silkworm (Antheraea mylitta Drury)

  • Vijayan, Kunjupillai;Singh, Ravindra Nath;Saratchandra, Beera
    • International Journal of Industrial Entomology and Biomaterials
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    • v.20 no.2
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    • pp.37-43
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    • 2010
  • The wild silkworm, Antheraea mylitta Drury (Lepidoptera: Saturniidae) is a polyphagous silk producing insect that feeds on Terminalia arjuna, T. tomentosa and Shorea robusta and is distributed in the forest belts in different states of India. Phenotypically distinct populations of the A. mylitta are called "eco-race" or "ecotypes". Genetic improvement of this wild silkworm has not progressed much due to lack of adequate information on the factors that control the expression of most of the economically important traits. Considering the amazing technological advances taking place in molecular biology, it is envisaged that it is now possible to take greater control on these intractable traits if a combination of genetic, molecular and bioinformatics tools are used. Linkage disequilibrium (LD) mapping is one such approach that has extensively been used in both animal and plant system to identify quantitative trait loci (QTLs) for a number of economically important traits. LD mapping has a number of advantages over conventional biparental linkage mapping. Therefore, LD mapping is considered more efficient for gene discovery to meet the challenge of connecting sequence diversity with heritable phenotypic differences. However, care must be taken to avoid detection of spurious associations which may occur due to population structure and variety interrelationships. In this review, we discuss how LD mapping is suitable for the dissection of complex traits in wild silkworms (Antheraea mylitta).

Automatic Linkage Model of Classification Systems Based on a Pretraining Language Model for Interconnecting Science and Technology with Job Information

  • Jeong, Hyun Ji;Jang, Gwangseon;Shin, Donggu;Kim, Tae Hyun
    • Journal of Information Science Theory and Practice
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    • v.10 no.spc
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    • pp.39-45
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    • 2022
  • For national industrial development in the Fourth Industrial Revolution, it is necessary to provide researchers with appropriate job information. This can be achieved by interconnecting the National Science and Technology Standard Classification System used for management of research activity with the Korean Employment Classification of Occupations used for job information management. In the present study, an automatic linkage model of classification systems is introduced based on a pre-trained language model for interconnecting science and technology information with job information. We propose for the first time an automatic model for linkage of classification systems. Our model effectively maps similar classes between the National Science & Technology Standard Classification System and Korean Employment Classification of Occupations. Moreover, the model increases interconnection performance by considering hierarchical features of classification systems. Experimental results show that precision and recall of the proposed model are about 0.82 and 0.84, respectively.

Improving the Linkage System between the Police and Social Welfare Agencies for Effective Response to Domestic Violence and Child Abuse in South Korea

  • Nam Young-Hee
    • International Journal of Advanced Culture Technology
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    • v.12 no.2
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    • pp.299-308
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    • 2024
  • This study aims to explore improvement measures for the linkage system between the police and social welfare agencies in responding to domestic violence and child abuse issues in South Korea by comparing and analyzing the current systems in South Korea, the United States, and the United Kingdom. Despite the legal and institutional foundations for victim protection and perpetrator correction in each country, the effectiveness of actual cooperation faces several limitations. In South Korea, the level of cooperation is insufficient due to the lack of information sharing, role conflicts, and ambiguity of cooperation procedures. The United States and the United Kingdom operate more systematic cooperation programs, showing notable achievements in mental health crisis intervention and domestic violence response. To improve the linkage system in South Korea, this study proposes the following measures: (1) developing a clear cooperation protocol, (2) conducting regular education and training programs, (3) establishing an integrated information system, and (4) strengthening the victim-centered approach. Implementing these measures will contribute to more effective responses to domestic violence and child abuse issues, ultimately leading to a healthier and safer society by reducing social costs through victim protection and perpetrator correction.

Research on Regional Smart Farm Data Linkage and Service Utilization (지역 스마트팜 데이터 연계 및 서비스 활용에 대한 연구)

  • Won-Goo Lee;Hyun Jung Koo;Cheol-Joo Chae
    • Journal of Practical Agriculture & Fisheries Research
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    • v.26 no.2
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    • pp.14-24
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    • 2024
  • To enhance the usability of smart agriculture, methods for utilizing smart farm data are required. Therefore, this study proposes a scheme for utilizing regional smart farm data by linking it to services. The current status of domestic and foreign smart farm data collection and linkage services is analyzed. To collect and link regional smart farm data, necessary data collection, data cleaning, data storage structure and schema, and data storage and linkage systems are proposed. Based on the standards currently being implemented for regional smart farm internal data storage, a farm schema, environmental information schema, facility control information schema, and growth information schema are designed by extending the crop schema and crop main environmental factor information database schema. A data collection and management system structure based on the Hadoop Ecosystem is designed for data collection and management at regional smart farm data centers. Strategies are proposed for utilizing regional smart farm data to provide smart farm productivity improvement and revenue optimization services, image-based crop analysis services, and virtual reality-based smart farm simulation services.

An Analysis on the Linkage Structure of Industrial Complexes(Clusters) in the Internal and External Capital Region (수도권 산업단지(클러스터)의 광역권 내부 및 외부 연계구조 분석)

  • Koo, Yang-Mi;Nahm, Kee-Bom;Park, Sam-Ock
    • Journal of the Economic Geographical Society of Korea
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    • v.13 no.2
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    • pp.181-195
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    • 2010
  • The policy of industrial complexes (innovative clusters) is being changed to build the linkage structure within Mega Economic Region according to the national policy of Mega Economic Region. The aim of this analysis is to draw the hypothetical linkage structure of industrial complexes in the internal and external Capital Region. First, with the survey data of firms located in the industrial complexes, we can catch the regional linkages of firms in the local area and internal and external Mega Economic Region. Next, the measure of structural similarity between industrial complexes is calculated with the number of employees by industrial sectors. After considering the geographical distance between industrial complexes, the percentage of industrial sectors and the location quotient synthetically, the idea of hub-and-spoke type linkage structure between clusters is deduced.

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Effect of Linkage Groups on the Properties of Semi-flexible Liquid Crystalline Polymers (연결기가 반 유연성 액정중합체의 물성에 미치는 영향)

  • Park, Jong-Ryul;Yoon, Doo-Soo;Bang, Moon-Soo
    • Applied Chemistry for Engineering
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    • v.26 no.4
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    • pp.445-451
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    • 2015
  • Semi-flexible liquid crystalline polymers containing a mesogenic group and an octamethylene flexible spacer in the main chain were synthesized by solution polycondensation. The mesogenic group in the polymer consists of four aromatic rings connected by ester and ketone, ether, sulfide, methylene, sulfone, or isopropylidene linkage groups. This paper discusses effects of the central linker of the mesogenic group on polymer properties. The structures and properties of synthesized polymers were investigated by $^1H$-NMR, FT-IR, differential scanning calorimeter (DSC), thermogravimetric analyzer (TGA), X-ray diffractometer (XRD), and polarizing optical microscope (POM). Polymers having bent linkage groups exhibited low thermal transition temperatures, narrow mesophase temperature ranges, low liquid crystallinity, and good solubilities in organic solvents, while those having bulky linkage groups were amorphous and exhibited high glass transition temperatures.

A Study of Disassembling Major Indication Terms into Minimum Meaning Units and Linking to Diseases (의미 단위 분해를 통한 주치와 병증 용어 연계 연구)

  • Kim, Anna;Oh, Yongtaek;Kim, Sangkyun;Kim, Sanghyun;Jang, Hyunchul
    • Herbal Formula Science
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    • v.21 no.2
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    • pp.72-80
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    • 2013
  • Objectives : Ontology is a good tool to represent the knowledge and has developed for Traditional Korean Medicine(TKM) in Korea Institute of Oriental Medicine. There are a lot of TKM terms, which have a complex meaning, especially major indication terms of medicinal treatment and terms of symptom and disease. These complex meaning terms result in the low linkage between major indication terms of medicinal treatment and terms of symptom and disease in TKM ontology. We studied to enhance the percentage of the linkage among those data in TKM ontology. Methods : We disassembled major indication terms of medicinal treatment into minimum meaning units and then linked them to enhance the percentage of the linkage among medicinal material, formula and disease ontology based on Traditional Korean Medicine. To retain objectivity, several experts of Korean Medicine used a web-based tool that supports users in refining terms and disassembling them into the minimum meaning efficiently. Results : The outcome shows that the percentage of the linkage among medicinal material, formula and disease ontology increased. By linking disassembled major indication terms to symptoms and diseases, the amount of information for medicinal materials and formulas also increased quantitatively in comparison with given formula for diseases in disease ontology. Conclusions : By this study, disassembled data increases the percentage of linkage between diseases and medicinal treatments. And the applicability of TKM ontology is also increased.

A Study on the Proposal of Direction of Data Linkage for Building a One-Stop Portal Service for Humanities Assets (인문자산 원스톱포털서비스 구축을 위한 데이터연계 방향성 제안 연구)

  • Noh, Younghee;Oh, Euikyung;Jeong, Dae-Keun
    • Journal of the Korean Society for information Management
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    • v.35 no.2
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    • pp.7-36
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    • 2018
  • The purpose of this study is to propose an effective direction of data linkage for building the humanities assets one-stop portal service. For this purpose, We collected and analyzed the actual status of the domestic institution with humanities assets, and presented the linkage direction through analysis of the data held by the target organization. The results of this study are as follows: First, we proposed a classification system of humanities assets based on the reviewing the existing classification system on the subject of humanities assets. Second, we set up the categories of potential data that can be incorporated into humanities assets through a detailed analysis of the subject and type of data held by the subject institutions. Third, we analyzed the platforms of similar case organizations providing one-stop portal services for humanities assets and proposed the applicable meta fields when constructing one-stop system based on similarity.

Suggestions for Building Coast-Inland Linkage Transport System to Promote Island Tourism (도서관광 활성화를 위한 연안-내륙 연계교통체계 구축 방향)

  • Choi, Chang-Ho
    • Journal of Korea Port Economic Association
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    • v.28 no.2
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    • pp.43-59
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    • 2012
  • Recently, there has been a noticeable increase in the number of tourists in islands that are well-known for their natural landscapes. It is expected that this number will go up steadily, due to the increase in per capita income and leisure time. Regarding tourism transportation, utilizing linkage transport between coastal passenger terminal and inland transport system is crucial. However, the existing system does not measure up to the expectations. This is attributable to the fact that the distances between coastal passenger terminals and inland transportation terminals are too far. Also, the current public transportation system lacks support and needs to take the role of connecting the two terminals. This study shows how coast-inland linkage transport system should be reformed in order to promote island tourism. It focuses on building linkage transport system and minimizing walking distance. Also, adjusting passenger ship schedule to the characteristics of island tourism is needed. For the sake of passengers, coastal passenger ship fare should be reduced, and integrated transport information should be provided.