• Title/Summary/Keyword: Linear program

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IMRT and IMRS Checking the Dose Distribution in the Small Field Evaluation of Measurement by Changes in SAD (IMRT 및 IMRS에서 Small Field의 선량분포 확인시 SAD 변화에 따른 측정의 유용성 평가)

  • Ko, Seung-Young;Kim, Sung-Joon;Park, Gir-Yong;Son, Mi-Suk;Lee, Nam-Ki;Kim, Jin-Soo
    • The Journal of Korean Society for Radiation Therapy
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    • v.22 no.1
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    • pp.33-39
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    • 2010
  • Purpose: It is very important to confirm conformance of dose distribution that is formed with treatment planning from IMRS or IMRT. It has been a problem dropped accuracy and conformance when the field size is getting smaller because of character of the 2D ion chamber. Verification of MatriXX Phantom dose distribution with a change in the SAD. Dose distribution measurement and analysis to improve the accuracy and should be useful to evaluate the award. Materials and Methods: A use of Novalis linear accelerator 6 MV photon beams. In general, IMRS were 25 patients with small field size. The selected patients were divided into three groups on the basis of the field size. SAD was changed from 80 to 130 cm and field size to determine the dose distribution to the change, each dose was measured using MatriXX Phantom. Analysis of measured values obtained from the program for each patient through the treatment planning system comparison and analysis of the dose distribution and gamma values were expressed. Result: SAD 80, 100, and 120 cm in size in the gamma value to the investigation of patients less than $3\;cm^2$ average 0.939, 0.969, and 0.979, respectively. Patients with more than $5\;cm^2$ 0.962, 0.983, and 0.988, respectively. $5\;cm^2$ or more patients 0.982, 0.990, and 0.992, respectively. Conclusion: The error rate of less than $3\;cm^2$ field size is increased rapidly. If the field size is increased, resolution is increased by 2D ion chambers. It has been approved that it can be credible if it is around $3\;cm^2$ when measuring dose distribution using MatriXX. Adjusting geometric field size by changing SAD is likely to be very useful when you measure dose distribution using MatriXX.

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Relations of neurological and social cognitions in patients with acute phase and chronic phase before returning to the community (급성기와 지역사회 복귀 전 만성 뇌졸중 환자의 신경학적 인지기능과 사회인지 기능의 관계)

  • Park, Myoung-Ok
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.5
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    • pp.549-556
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    • 2017
  • This study investigated the importance of social cognitive intervention and the cognitive rehabilitation intervention by comparing the difference and examining the relationship between neurological cognitive function and social cognitive function of stroke patients in the acute phase and chronic stroke before returning to the community. LOTCA, cartoon intention inference task, and social behavior sequence task were performed on 30 acute stroke inpatients and 30 chronic stroke patients from May 2015 to June 2016. A two sample t test was conducted to examine the differences between the groups. The Pearson's correlations test was performed to examine the correlation among the variables in each group. As a result, there were statistically significant differences between the neurological cognitive function and social cognitive function of acute stroke patients and chronic stroke patients who were undergoing rehabilitation training before returning to the community (p<0.05). A linear relationship was found between the thinking operation and social behavior sequence task in the acute stroke group (r=0.539, p<0.05). In the chronic stroke group, visual perception (r=0.530, p<0.05), visual motor organization (r=0.655, p<0.05) and thinking operation (r=0.534, p<0.05) were correlated with the cartoon intention inference task. In addition, the social behavior sequence task were correlated with visual organization (r=0.534, p<0.05) and thinking operation (r=0.764, p<0.05). As a result of multiple regression analysis, the neurological cognitive functions influencing the social cognitive function in the cartoon task was found to be the thinking operation (B = 0.431) in acute stroke patients and the thinking operation (B=0.272) and visuomotor organization (B = 0.218) in the case of chronic stroke. In addition, the results of the social behavior sequence task revealed the thinking operation (B=0.417) in the acute stroke patients, and thinking operation (B=0.267), visual motor organization(B=0.274) and visual perception(B=151) in chronic stroke patients to be significant. According to this result, there is a difference in the neurological and social cognitive levels between the two groups. Therefore, the social cognition is strongly related to the high level cognitive function as thinking operation of the neurological cognitive function. Therefore, in further research, it would be necessary to determine if there is a change in higher cognitive function in neurological cognitive function after applying a social cognition intervention program for stroke.

Determination of Electron Spin Relaxation Time of the Gadolinium-Chealted MRI Contrast Agents by Using an X-band EPR Technique (EPR을 통한 상자성 자기공명 조영제의 전자스핀 이완시간의 결정)

  • Sung-wook Hong;Yongmin Chang;Moon-jung Hwang;Il-su Rhee;Duk-Sik Kang
    • Investigative Magnetic Resonance Imaging
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    • v.4 no.1
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    • pp.27-33
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    • 2000
  • Purpose: To determine the electronic spin relaxation times, $T_{le}$, of three commercially available Gd-chelated MR contrast agents, Gd-DTPA, Gd-DTPA-BMA and Gd-DOTA, using Electron Paramagnetic Resonance(EPR) technique. Material and Methods: The paramagnetic MR contrast agents, Gd-DTFA(Magnevist) , Gd-DTFA-BMA(OMNISCAN) and Gd-DOTA(Dotarem), were used for this study, The EPR spectra of these contrast agents, which were prepared 2:1 methanol/water solution, were obtained at low temperatures, from $-160^{\circ}C~20^{\circ}C$. The glassy-state EPR spectra for these contrast agents were then fitted by the simulation spectra generated with different zero-field splitting (ZFS) parameters by a computer simulation program 'GEN', which generates the EPR powder spectrum using a given ZFS in $3{\times}3$ tensor. Finally, the spin relaxation times of the contrast agents were then determined from the $T_{2e}$, D, and E values of the best simulation spectra using the McLachlan's theory of average relaxation rate. Results: The electronic transverse spin relaxation times, $T_{2e}'s$, of Gd-DTPA, Gd-DTPA-BMA and Gd-DOTA were 0.113ns, 0.147ns and 1.81ns respectively. The g-values were 1.9737, 1.9735 and 1.9830 and the electronic spin relaxation times, $T_{1e}'s$, were 18.70ns, 33.40ns and $1.66{\mu}s$, respectively. Conclusion: The results of these studies reconfirm that the paramagnetic MR contrast agents with larger ZFS parameters should have shorter $T_{1e}'s$. Among three contrast agents used for this study, Gd-DOTA chelated with cyclic ligand structure shows better electronic property then the others with linear structure. Thus, it is concluded that the exact determination of ZFS parameters is the important factor in evaluating relaxation enhancement effect of the agents and in developing new contrast agents.

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The Associated Factors with Xerostomia in Adults Aged 30 Years and Over (일부 만 30세 이상 성인에서 구강건조증 관련요인 분석)

  • Han, Hae-Seong;Kwon, Da-Ae;Kim, Ri-Na;Kim, Yu-Na;Lee, Gyeol-Hui;Lee, Na-Ram;Lee, Da-Jeong;Lee, Seung-Hui;Choi, Jun-Seon
    • Journal of dental hygiene science
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    • v.13 no.1
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    • pp.62-70
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    • 2013
  • The aim of this study was to analyze factors related to xerostomia in adults aged 30 years and over. The data were analyzed using the t-test, one-way ANOVA and multiple linear regression analysis in the SPSS version 12.0 program. The results were as follow. 1. The respondents who were older than 51 years old, unemployed and had less than 3 million won of average monthly income were more aware of xerostomia (p<0.05). 2. The respondents who answered poor and moderate for their general and oral health and the group with duplicate medication and comorbidity were more aware of xerostomia (p<0.05). 3. The respondents that had problems in chewing, communication, ordinary activities and complained of pain discomfort and suffered from anxiety depression were more aware of xerostomia (p<0.001). 4. The respondents that answered frequent dryness on their skin, eyes, lips, and nasal mucosa were more aware of xerostomia (p<0.001). 5. Xerostomia showed highest correlation with quality of life ($\beta$=0.436) followed by the number of medications ($\beta$=0.239), sense of entire body dryness ($\beta$=0.200), feeling of hopelessness ($\beta$=0.160) and number of oral mucosa disease symptoms ($\beta$=0.099) (p<0.05). According to the results of the study, xerostomia may cause deterioration in quality of life. Thus, it is advised to improve the patient management system among dental professions to prevent various complications caused by xerostomia and conduct regular health education on the cause and management method of xerostomia.

Effect of presurgical nasoalveolar molding (PNAM) appliance and cheiloplasty on alveolar molding of complete unilateral cleft lip and palate patients (완전 편측성 순구개열 신생아 환자의 술전 비치조 정형장치와 구순열 수술이 치조골 정형에 미치는 효과)

  • Kim, Na-Young;Lee, Shin-Jae;Baek, Seung-Hak
    • The korean journal of orthodontics
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    • v.33 no.4 s.99
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    • pp.235-245
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    • 2003
  • The goal of the present study was to evaluate the effects of PNAM appliance and cheiloplasty on alveolar molding. Samples consisted of 16 unilateral cleft lip and palate infants (10 males and 6 female, mean age=37.0 days after birth, average alveolar cleft gap=10.46m), who were treated with PNAM appliances by one orthodontist and rotation- advancement cheiloplasty by one surgeon in Seoul National University Hospital. Average duration of alveolar molding treatment was 13.10 weeks and these patients were recalled at average 8.31 weeks after cheiloplasty. These patients' models were obtained at initial visit (T0, mean age : $37.0\pm27.89$ days after birth), after successful alveolar molding (T1, mean age : $119.25\pm40.18$ days after birth), and after cheilopasty (T2, mean age : $190.81\pm42.78$ days after birth). Seven linear and five angular variables were measured using 1 : 1 photometry and soft ware program(V-ceph. Cybermed. Seoul, Korea). Paired t-test was performed to investigate statistical significance at p<0.05 level. 1 The posterior parts of alveolar segments were the stable structures during alveolar molding treatment period and after cheiloplasty in infants. 2. The closure of cleft gap during alveolar molding was usually due to backward bending of the whole part of the greater segment. 3. Although forward growth of the greater segment was hindered by alveolar molding, it resumed after cheiloplasty. 4. Increase of anterior inter-segment angle after cheiloplasty was due to the molding effect of the lip scar pressure.

Study on the Genetic Correlations of Body Weights and the Growth Rates from 2- to 8-weeks of Age in Broiler Chicken (Broiler 성장단계별 체중에 대한 유전상관과 성별 성장률에 관한 연구)

  • Ohh, Bong-Kug;Yang, Young-Whoun;Sohn, Sea-Hwan;Lee, Moun-Yeoun
    • Korean Journal of Poultry Science
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    • v.12 no.2
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    • pp.53-57
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    • 1985
  • This study was carried out to estimate genetic correlations among broiler body weights for the selection of broiler breeders at early age, and to investigate the difference of growth rates between male and female in mixed-sex population of broiler from 2wks to 8 wks of age. A total of 1109 records were used in this study. the heritability estimates from combined variance components for 2-,4-, 6- and 8- weeks body weights were 0.32, 0.31, 0.35 and 0.29 respectively. Genetic correlations were 0.91 between 4wks and 8wks body weights, 0.94 between 6wks and 8wks body weights. Records obtained on 4wks and 8wks might be useful in a selection program to improve traits in 8wks broiler weight. Growth rates of male and female from nonlinear equations from 2wks to 8wks were shown differently in both linear and quadratic terms, Even though both sexes showed closely equal body weights at 2wks of age, they manifested great difference about 300g at 8wks of age. At all. ages roles were havier, grew at a faster than female. From this result it might be profitable either to select the combination of lines which has little sex effect or to rear male and female broiler separately up to the marketing body weights.

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Calculation of Renal Depth by Conjugate-View Method Using Dual-head Gamma Camera (이중 헤드 감마 카메라를 이용한 Conjugate-View 계수법에 의한 신장 깊이 도출)

  • Kim, Hyun-Mi;Suh, Tae-Suk;Choe, Bo-Young;Chung, Yong-An;Kim, Sung-Hoon;Chung, Soo-Kyo;Lee, Hyoung-Koo
    • The Korean Journal of Nuclear Medicine
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    • v.35 no.6
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    • pp.378-388
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    • 2001
  • Purpose: In this study, we developed a new method for the determination of renal depth with anterior and posterior renal scintigrams in a dual-head gamma camera, considering the attenuation factor $e^{-{\mu}x}$ of the conjugate-view method. Material and Method: We developed abdomen and kidney phantoms to perform experiments using Technetium-99m dimercaptosuccinic acid ($^{99m}Tc$-DMSA). The phantom images were obtained by dual-head gamma camera equipped with low-energy, high-resolution, parallel-hole collimators (ICONf, Siemens). The equation was derived from the linear integration of omission ${\gamma}$-ray considering attenuation from the posterior abdomen to the anterior abdomen phantom surface. The program for measurement was developed by Microsoft Visual C++ 6.0. Results : Renal depths of the phantoms were derived from the derived equations and compared with the exact geometrical values. Differences between the measured and the calculated values were the range of 0.1 to 0.7 cm ($0.029{\pm}0.15cm,\;mean{\pm}S.D.$). Conclusion: The present study showed that the use of the derived equations for renal depth measurements, combined with quantitative planar imaging using dual-head gamma camera, could provide more accurate results for individual variation than the conventional method.

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Arm Span-Height Relationship for Prediction of Spirometric Values in Korean Adult Women (우리나라 성인여성에서 정상 폐활량 예측을 위한 양팔벌린 손끝길이와 신장과의 관계)

  • Koh, Won-Jung;Ju, Young-Su;Kim, Tae-Yub;Park, Jae-Sung;Yu, Seung-Do;Choi, Kwaung-Soo;Paek, Do-Myung;Han, Sung-Koo;Shim, Young-Soo
    • Tuberculosis and Respiratory Diseases
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    • v.46 no.6
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    • pp.786-794
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    • 1999
  • Back ground : Arm span measurements provide a practical substitute for standing height to predict normal spirometric values in subjects unable to stand or those with a skeletal deformity such as kyphoscoliosis. The relationship between arm span and height has previously been reported as either a fixed ratio unaffected by age or as a regression equation in which the ratio varies as a function of age. The fixed ratio or regression equation is known to be specific for sex and race. Methods : We studied the relationship between standing height, arm span, and age in 381 Korean adult female subjects (ages 20 to 69 yrs) sampled in a general population. Results : The mean ratio for arm span to height is 1.004. Multiple linear analysis found arm span and age to be predictive of standing height (p=0.0001, $r^2$=0.76). We performed the analysis of the difference between the predicted height using either fixed ratio or regression equation and actual height. At the extremes of arm span and age, the ratio method either underestimated(at smaller arm span or younger age) or overestimated(at larger arm span or older age) as compared with actual height (p=0.0001). Conclusion : This results indicate that the estimated height using the fixed ratio method provides a less acceptable method of estimating height for the prediction of lung volumes in the Korean adult women when compared with the regression equations, especially at the extremes of stature or age.

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Temperature-dependent Development Model of Paromius exiguus (Distant) (Heteroptera: Lygaeidae) (흑다리긴노린재[Paromius exiguus (Distant)] 온도발육 모형)

  • Park, Chang-Gyu;Park, Hong-Hyun;Uhm, Ki-Baik;Lee, Joon-Ho
    • Korean journal of applied entomology
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    • v.49 no.4
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    • pp.305-312
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    • 2010
  • The developmental time of immature stages of Paromius exiguus (Distant) was investigated at nine constant temperatures (15, 17.5, 20, 22.5, 25, 27.5, 30, 32.5, $35{\pm}1^{\circ}C$), 20-30% RH, and a photoperiod of 14:10h (L:D). Eggs did not develop at $15^{\circ}C$, and their developmental time decreased with increasing temperatures. Its developmental time was longest at $17.5^{\circ}C$ (28.2 days) and shortest at $35^{\circ}C$ (5.9 days). The first nymphs failed to reach the next nymphal stage at 17.5 and $35^{\circ}C$. Nymphal developmental time decreased with increasing temperatures between $20^{\circ}C$ and $32.5^{\circ}C$, and developmental rate was decreased at temperatures above $30^{\circ}C$ in all stages except for the fourth nymphal stage. The relationship between developmental rate and temperature fit a linear model and three nonlinear models (Briere 1, Lactin 2, and Logan 6). The lower threshold temperature of egg and total nymphal stage was $l3.8^{\circ}C$ and $15.3^{\circ}C$, respectively. The thermal constant required to reach complete egg and the total nymphal stage was 109.9 and 312.5DD, respectively. The Logan-6 model was best fitted ($r^2$=0.94-0.99), among three nonlinear models. The distribution of completion of each development stage was well described by the 3-parameter Weibull function ($r^2$=0.91-0.99).

Dose Distribution According to the Tissue Composition Using Wedge Filter by Radiochromic Film (쐐기필터 사용 시 레디오크로믹 필름을 이용한 조직에 따른 선량분포 연구)

  • Kim, Yon-Lae;Lee, Jeong-Woo;Park, Byung-Moon;Jung, Jae-Yong;Park, Ji-Yeon;Suh, Tae-Suk
    • Journal of radiological science and technology
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    • v.35 no.2
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    • pp.157-164
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    • 2012
  • The purpose of this study is to analyze the dose distribution when wedge filter is used in the various tissue electron density materials. The dose distribution was assessed that the enhanced dynamic wedge filter and physical wedge filter were used in the solid water phantom, cork phantom, and air cavity. The film dosimetry was suitable simple to measure 2D dose distribution. Therefore, the radiochromic films (Gafchromic EBT2, ISP, NJ, USA) were selected to measure and to analyze the dose distributions. A linear accelerator using 6 MV photon were irradiated to field size of $10{\times}10cm^2$ with 400 MUs. The dose distributions of EBT2 films were analyzed the in-field area and penumbra regions by using dose analysis program. In the dose distributions of wedge field, the dose from a physical wedge was higher than that from a dynamic wedge at the same electron density materials. A dose distributions of wedge type in the solid water phantom and the cork phantom were in agreements with 2%. However, the dose distribution in air cavity showed the large difference with those in the solid water phantom or cork phantom dose distributions. Dose distribution of wedge field in air cavity was not shown the wedge effect. The penumbra width, out of the field of thick and thin, was observed larger from 1 cm to 2 cm at the thick end. The penumbra of physical wedge filter was much larger average 6% than the dynamic wedge filter. If the physical wedge filter is used, the dose was increased to effect the scatter that interacted with photon and physical wedge. In the case of difference in electron like the soft tissue, lung, and air, the transmission, absorption, and scattering were changed in the medium at high energy photon. Therefore, the treatment at the difference electron density should be inhomogeneity correction in treatment planning system.