• Earthquakes and Structures
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• v.10 no.3
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• pp.629-643
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• 2016

Among all the natural disasters, earthquakes are the most destructive calamities since they cause a plenty of injuries and economic losses leaving behind a series of signs of panic. The present study highlights the moment-curvature relationships for the structural elements such as beam and column elements and Non-Linear Static Pushover Analysis of RC frame structures since it is a very simplified procedure of non-linear static analysis. The highly popular model namely Mander's model and Kent and Park model are considered and then, seismic risk evaluation of RC building has been conducted using SAP 2000 version 17 treating uncertainty in strength as a parameter. From the obtained capacity and demand curves, the performance level of the structure has been defined. The seismic fragility curves were developed for the variations in the material strength and damage state threshold are calculated. Also the comparison of experimental and analytical results has been conducted.

• The Korean Journal of Pesticide Science
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• v.6 no.4
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• pp.231-243
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• 2002

Starting with linear free energy relationships (LFER), drug design to mimic of the activated complexes at transition state, and hydrolysis mechanisms to control the potency and residual properties of pesticides were introduced and summarized for the necessity. In order to understand the searching or development of new agrochemicals by two dimensional quantitative structure-activity relationship (2D QSAR) methodology, a series of the various descriptors, steric constants, electronic constants including quantum pharmacological parameters and hydrophobic constants were classified and discussed for results of the several studied cases. In addition, the processes of development of new agrochemicals by QSAR techniques were introduced simply.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.11 no.2
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• pp.169-174
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• 2018

In general, the methods of the analysis of variance(ANOVA) for the continuous data and the chi-square test for the discrete data are used for statistical analysis of the effect and the association. In multidimensional data, analysis of hierarchical structure is required and statistical linear model is adopted. The structure of the linear model requires the normality of the data. A multidimensional categorical data analysis methods are used for causal relations, interactions, and correlation analysis. In this paper, Bayesian network model using probability distribution is proposed to reduce analysis procedure and analyze interactions and causal relationships in categorical data analysis.

• Molecular & Cellular Toxicology
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• v.4 no.2
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• pp.170-176
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• 2008

The quantitative structure-activity relationship (QSAR) of a set of 35 flavonoid compounds presenting antioxidant activity was established by means of Genetic Algorithm-Multiple Linear Regression (GA-MLR) technique. Four-parametric models for two sets of data, the 1,1-diphenyl-2-picryl hydrazyl (DPPH) radical scavenging activity $(R^2=0.788,\;Q^2_{cv}=0.699\;and\;Q^2_{ext}=0.577)$ and scavenging activity of reactive oxgen species (ROS) induced by $H_2O_2 (R^=0.829,\;Q^2_{cv}=0.754\;and\;Q^2_{ext}=0.573)$ were obtained with low external predictive ability on a mass basis, respectively. Each model gave some different mechanistic aspects of the flavonoid compounds tested in terms of the radical scavenging activity. Topological charge, H-bonding complex and deprotonation processes were likely to be involved in the radical scavenging activity.

• Korean Journal of Materials Research
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• v.13 no.2
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• pp.81-87
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• 2003

Microstructures and mechanical properties of variously heat treated 0.85% carbon steel(eutectoid steel) were evaluated by magnetic property measurements. Microstructural analysis (pearlite interstellar spacing), measurement of mechanical properties(Rockwell hardness, yield stress, fracture stress) and magnetic properties(coercivity, remanence, hysteresis loss, saturation magnetization) were performed to clarify mutual relationships among these parameters. Water quenched specimens with martensite structure showed much higher coercivity and remanence than air cooled or furnace cooled specimens with pearlite structure. The linear dependence of coercivity and remanence on pearlite interlamellar spacing as well as on Rockwell hardness, yield stress and fracture stress was observed in the pearlitic steel. Hysteresis loss and saturation magnetization showed no distinct trend with pearlite interlamellar spacing.

• Applied Biological Chemistry
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• v.35 no.1
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• pp.14-22
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• 1992

A series of new N-[1-(benzotriazol-1-yl)aryl]arylamine derivatives were synthesized and their antifungal activities $(pI_{50})$ in vitro against Pyricularia oryzae, Fusarium oxysporum f. sp. sesami, Valsa ceratosperma and Botrytis cinerea were dertermined by the agar medium dilution method. From the results of the quantitative structure-activity relationships $(QSAR_S)$ analysis, $hydrophobicity({\pi})$, $electronic({\Sigma\sigma})$ and molar $refractivity({\Sigma}M_R)$ parameter of X & Y-substituents on the phenyl group were also shown to be important factor in determining the variation in the antifungal activity. 4-Bromo group substituents (1d & 2b) were the most effective compounds and the $half-life(T_{1/2})$ on the hydrolysis of X(1) at netural pH was about 1.5 day. Molecular orbital(MO) functions of substrate compound, linear free energy relationships$(LFER_S)$ on the antifungal reactivity arid the results of molecular design were also discussed.

• Bulletin of the Korean Chemical Society
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• v.27 no.2
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• pp.211-218
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• 2006

This work deals with 24 substances composed of nitrogen-containing heterocycles. The relationships between the chromatographic retention factor (k) and those physicochemical properties which are relevant in quantitative structure-properties relationship (QSPR) studies, such as the polarizability $(\alpha)$, molar refractivity (MR), lipophilicity (logP), dipole moment $(\mu)$, total energy $(E_{tot})$, heat of formation $(\Delta H_f)$, molecular surface area $(S_M)$, and binding energy $(E_b)$, were investigated. The accuracy of the simple linear regressions between the chromatographic retention and the descriptors for all of the compounds was satisfactory (correlation coefficient, $0.8 \leq r \leq 1.0$). The QSPR models of these nitrogen-containing heterocyclic compounds could be predicted with a multiple linear regression equation having the statistical index, r = 1.000. This work demonstrated the successful application of the multiple linear approaches through the development of accurate predictive equations for retention factors in liquid chromatography.

• ALGAE
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• v.23 no.2
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• pp.141-150
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• 2008

Populations of Codium amplivesiculatum were found in association with rhodolith beds. We present population trends of C. amplivesiculatum from surveys conducted in the southwestern Gulf of California based on monthly sampling from June 1999 to August 2000. Surveys were conducted at 2 sites in the San Lorenzo Channel at depths of 8 - 12 m. The parameters measured were percent cover, biomass and structure in relation to size of the thalli. From each thallus the following measurements were taken: length and diameter, proportion of each thallus with reproductive structures and the degree of fragmentation (measured as number of small thalli). Mean biomass and cover varied seasonally with the maximum (1036.6 gm$^{-2}$ and 100% cover) present in June 2000 and the minimum in winter (0 gm$^{-2}$ and 0% cover). The longest fronds (3 m) occurred during July 1999 and August 2000, while the maximum diameters of 1.0 cm were present during October and November 1999. There were no significant linear relationships between length and diameter of the fronds, suggesting independent growth. Reproductive structures were common in June and July 1999 with monoic and dioic thalli present. Most fronds were monoic, and this is the first record of this feature for this species. Fragmentation occurred in September, and may be associated with stress from early gametangial reproduction and the combination of high temperatures and low nutrients. A hypothetical life cycle for the species is presented.

• Geomechanics and Engineering
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• v.18 no.3
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• pp.299-313
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• 2019

This research investigated the nonlinear compressibility, permeability, the yielding due to structural degradation and their effects on consolidation behavior of structured soft soils. Based on oedometer and hydraulic conductivity test results of natural and reconstituted soft clays, linear log (1+e) ~ $log\;{\sigma}^{\prime}$ and log (1+e) ~ $log\;k_v$ relationships were developed to capture the variations in compressibility and permeability, and the yield stress ratio (YSR) was introduced to characterize the soil structure of natural soft clay. Semi-analytical solutions for one-dimensional consolidation of soft clay under time-dependent loading incorporating the effects of soil nonlinearity and soil structure were proposed. The semi-analytical solutions were verified against field measurements of a well-documented test embankment and they can give better accuracy in prediction of excess pore pressure compared to the predictions using the existing analytical solutions. Additionally, parametric studies were conducted to analyze the effects of YSR, compression index (${\lambda}_r$ and ${\lambda}_c$), and permeability index (${\eta}_k$) on the consolidation behavior of structured soft clays. The magnitude of the difference between degree of consolidation based on excess pore pressure ($U_p$) and that based on strain ($U_s$) depends on YSR. The parameter ${\lambda}_c/{\eta}_k$ plays a significant role in predicting consolidation behavior.

• Advances in nano research
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• v.15 no.3
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• pp.215-224
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• 2023

Nonlinearity plays an important role in control systems and the application of design. For this reason, in addition to linear vibrations, nonlinear vibrations of the stepped nanobeam are also discussed in this manuscript. This study investigated the vibrations of stepped nanobeams according to Eringen's nonlocal elasticity theory. Eringen's nonlocal elasticity theory was used to capture the nanoscale effect. The nanoscale stepped Euler Bernoulli beam is considered. The equations of motion representing the motion of the beam are found by Hamilton's principle. The equations were subjected to nondimensionalization to make them independent of the dimensions and physical structure of the material. The equations of motion were found using the multi-time scale method, which is one of the approximate solution methods, perturbation methods. The first section of the series obtained from the perturbation solution represents a linear problem. The linear problem's natural frequencies are found for the simple-simple boundary condition. The second-order part of the perturbation solution is the nonlinear terms and is used as corrections to the linear problem. The system's amplitude and phase modulation equations are found in the results part of the problem. Nonlinear frequency-amplitude, and external frequency-amplitude relationships are discussed. The location of the step, the radius ratios of the steps, and the changes of the small-scale parameter of the theory were investigated and their effects on nonlinear vibrations under simple-simple boundary conditions were observed by making comparisons. The results are presented via tables and graphs. The current beam model can assist in designing and fabricating integrated such as nano-sensors and nano-actuators.