• Title/Summary/Keyword: Linear Stability

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Structural ordering, electronic and magnetic properties of bundled $Mo_6S_9-_xI_x$ nanowires

  • Kang, Seoung-Hun;Tomanek, David;Kwon, Young-Kyun
    • Proceedings of the Korean Vacuum Society Conference
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    • 2010.02a
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    • pp.55-55
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    • 2010
  • We use ab initio density functional theory to determine the effect of bundling on the equilibrium structure, electronic and magnetic properties of $Mo_6S_{9-x}I_x$nanowires with x = 0, 3, 4.5, 6. Each unit cell of these systems contains two $Mo_6S_{6-x}I_x$ clusters connected by S3 linkages to form an ordered linear array. Due to the bi-stability of the sulfur linkages, the total energy of the nanowires exhibits typically many minima as a function of the wire length. We find that nanowires can switch over from metallic to semiconducting by applying axial stress. Structural order is expected in bundles with x=0 and x=6, since there is no disorder in the decoration of the Mo clusters. In bundles with other stoichiometries, we expect structural disorder to occur. We find the optimum inter-wire distance to depend sensitively on the orientation of the wires, but only weakly on x. It is also found that the electronic properties of nanowires are affected strongly due to bundling of nanowires exhibiting very unusual Fermi surfaces. Furthermore, ferromagnetic behaviors are observed in selected stable and many more unstable atomic arrangements in nanowire bundles.

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Post-Translational Regulations of Transcriptional Activity of RUNX2

  • Kim, Hyun-Jung;Kim, Woo-Jin;Ryoo, Hyun-Mo
    • Molecules and Cells
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    • v.43 no.2
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    • pp.160-167
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    • 2020
  • Runt-related transcription factor 2 (RUNX2) is a key transcription factor for bone formation and osteoblast differentiation. Various signaling pathways and mechanisms that regulate the expression and transcriptional activity of RUNX2 have been thoroughly investigated since the involvement of RUNX2 was first reported in bone formation. As the regulation of Runx2 expression by extracellular signals has recently been reviewed, this review focuses on the regulation of post-translational RUNX2 activity. Transcriptional activity of RUNX2 is regulated at the post-translational level by various enzymes including kinases, acetyl transferases, deacetylases, ubiquitin E3 ligases, and prolyl isomerases. We describe a sequential and linear causality between post-translational modifications of RUNX2 by these enzymes. RUNX2 is one of the most important osteogenic transcription factors; however, it is not a suitable drug target. Here, we suggest enzymes that directly regulate the stability and/or transcriptional activity of RUNX2 at a post-translational level as effective drug targets for treating bone diseases.

Parameter Analysis of Rotor Shape Modification for Reduction of Squeal Noise (브레이크의 스퀼 저감을 위한 로터 형상변경 파라메터 해석)

  • Lee, Hyun-Young;Oh, Jae-Eung;Cha, Byeong-Gyu;Joe, Yong-Goo;Lee, Jung-Youn
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2004.11a
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    • pp.820-825
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    • 2004
  • This paper deals with friction-induced vibration of disc brake system under constant friction coefficient. A linear, finite element parameter model to represent the floating caliper disc brake system is proposed. The complex eigenvalues are used to investigate the dynamic stability and in order to verify simulations which are based on the FEM model, the experimental modal test and the dynamometer test are performed. The comparison of experimental and simulation results shows a good agreement and the analysis indicates that mode coupling due to friction force is responsible for disc brake squeal. And squeal type instability is investigated by using the parametric rotor simulation. This indicates parameters which have influence on the propensity of brake squeal. This helped to validate the FEM model and establish confidence in the simulation results. Also they may be useful during real disk brake model.

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Face Recognition Using Modified Two-Dimensional PCA (변형된 이차원 PCA를 이용한 얼굴 인식)

  • Kim Young-Gil;Song Young-Jun;Chang Un-Dong;Kim Dong-Woo;Ahn Jae-Hyeong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.6 no.4
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    • pp.291-295
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    • 2005
  • In this paper, we propose a face recognition method using modified 2-D PCA. While the previous PCA method computes the covariance matrix by using one dimensional vectors, the 2-D PCA method computes the covariance matrix by directly using direct two dimensional image, and extracts the feature vectors by solving eigenvalue problem. The proposed method recognizes the faces by applying the modified 2-D PCA to face images and it gets linear transformation matrix using two covariance matrices. The experimental results indicates that the proposed method improved about $1\%$ and achieved more stability in recognition rate than conventional 2-D PCA.

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A Robust Dynamic Decoupling Control Scheme for PMSM Current Loops Based on Improved Sliding Mode Observer

  • Shen, Hanlin;Luo, Xin;Liang, Guilin;Shen, Anwen
    • Journal of Power Electronics
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    • v.18 no.6
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    • pp.1708-1719
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    • 2018
  • A complete current loop decoupling control strategy based on a sliding mode observer (SMO) is proposed to eliminate the influence of current dynamic coupling and back electromotive force (EMF) in the vector control of permanent magnet synchronous motors. With this strategy, current dynamic decoupling and back EMF compensation can be simultaneously achieved. Unlike conventional methods, the proposed strategy can avoid the disturbances caused by the parametric variations of motor systems and maintain the advantages of proportional integral (PI) controllers, which are robust and easy to operate. An improved SMO, which uses a special PI regulator other than a linear saturation function as the equivalent control law in the boundary layer of a sliding surface, is proposed to eliminate the estimated errors caused by the quasi-sliding mode and obtain a satisfactory decoupling performance. The stability and parameter robustness of the proposed strategy are also analyzed. Physical experimental results are presented to verify the validity of the method.

Application of Energy-Dissipating Sacrificial Device(EDSD) for Enhancing Seismic Performance of Bridges (교량의 내진성능 향상을 위한 희생부재형 에너지소산장치(EDSD)의 적용에 관한 연구)

  • Kim, Sang-Hyo;Cho, Kwang-Yil;Kim, Hae-Young
    • Proceedings of the Earthquake Engineering Society of Korea Conference
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    • 2006.03a
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    • pp.445-452
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    • 2006
  • A new Energy-Dissipating Sacrificial Device(EDSD) is proposed, which can effectively dissipate the energy stored in the structures during seismic actions. A mathematical 3-D bridge models and analysis techniques are developed to represent the non-linear behavior of the EDSD, various seismic responses of a sample bridge with the EDSD are analyzed in terms of energy, member forces and deformation using the developed analysis method. And the EDSD is tested and certified it's behavior and stability to apply on exiting bridges. The EDSD can be able to dissipate a large amount of energy and therefore it can prevent the pier's excessive forces under seismic excitations and EDSD and its connected members are also stable. Additionally, the method and guidelines of an optimum EDSD design are proposed in terms of installation method and decision of number of EDSD. The Proposed EDSD under seismic excitations can significantly decrease the excessive storing energy in the bridge structures and reduce the relative displacements of each superstructure to the ground. The EDSD is also found to function as a structural fuse under strong ground motions, sacrificing itself to absorb the excessive energy. Consequently, economical enhancement of the seismic performance of bridges can be achieved by employing the newly developed energy dissipation sacrificial device(EDSD).

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A Proposal of 3 Point Search Algorithm for Optimal Design (최적 설계를 위한 3점 탐색 알고리즘의 제안)

  • 김주홍;공휘식
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.16 no.7
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    • pp.640-650
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    • 1991
  • In the paper, the threepoint search algorithm used direct search method for optimal design is proposed. Proposed algorithm is composed of two iteration procedure to determine the minimum value of performance index. The minumum value of three-point existing in the inner N-order searching is firstly determined and next searching space is then reduced by the result of first procedure. To compute performance index. 3N iteration for a searching is necessary. 3N searching method is also described and confirmed with exception of parameter included multiphicator and divisor. Proposed algorithm have good stability and reliability when performance index is linear or quadratic function.

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Development a GB-SAR (I) : System Configuration and Interferometry (GB-SAR의 개발 (I) : 시스템 구성과 간섭기법)

  • Lee, Hoon-Yol;Sung, Nak-Hoon;Kim, Jung-Ho;Cho, Seong-Jun
    • Korean Journal of Remote Sensing
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    • v.23 no.4
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    • pp.237-245
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    • 2007
  • GB-SAR (Ground-Based Synthetic Aperture Radar) system is an imaging radar that obtains high resolution 2-D image through a synthetic aperture effect from the accurate linear-motion control of antenna on the ground. The highly versatile system configurations and accurate repeatability of GB-SAR operation allow one to accurately monitor the stability of surface scatterers with millimeter accuracy by SAR interferometry. In this paper we introduce the development of a GB-SAR system and show the possibilities of SAR polarimetry and interferometry such as DInSAR, Cross-Track InSAR, Delta-f InSAR, and PSInSAR.

Development of Sensitive Analytical Method of Rhodanthpyrone A by a LC-MS/MS and its Application to Bioavailability Study in Rats

  • Kang, Bitna;Yoon, Jeong A;Song, Im-Sook;Han, Young Taek;Choi, Min-Koo
    • Mass Spectrometry Letters
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    • v.10 no.3
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    • pp.88-92
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    • 2019
  • A sensitive analytical method of rhodanthpyrone A in rat plasma was developed using a liquid chromatography-tandem mass spectrometry (LC-MS/MS). Rhodanthpyrone A and rhodanthpyrone B (internal standard) in rat plasma were extracted by a liquid-liquid extraction method with ethyl acetate. This extraction method gave results in high and reproducible extraction recovery in the range of 73.75-79.90% with no interfering peaks around the peak elution time of rhodanthpyrone A and B. The standard calibration curves for rhodanthpyrone A ranged from 0.5 to 2000 ng/mL were linear with $r^2$ > 0.994 and the inter- and intra-day accuracy and precision and the stability were within acceptance criteria. Using this validated analytical method, pharmacokinetics of rhodanthpyrone A following intravenous and oral administration of rhodanthpyrone A at doses of 2 mg/kg and 30 mg/kg, respectively, were investigated. Rhodanthpyrone A in rat plasma showed multi-exponential elimination pattern with high clearance and volume of distribution values. The absolute oral bioavailability of this compound was calculated as 3.7%. Collectively, the newly developed sensitive LC-MS/MS analytical method of rhodanthpyrone A could be successfully applied to investigate the pharmacokinetic properties of this compound and would be useful for the further studies on the efficacy, toxicity, and biopharmaceutics of rhodanthpyrone A.

A Linear Stability Analysis of Unsteady Combustion of Solid Propellants (고체추진제 비-정상연소의 선형 안정성해석)

  • 이창진;김성인;변영환
    • Journal of the Korean Society of Propulsion Engineers
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    • v.2 no.1
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    • pp.59-66
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    • 1998
  • The combustion instability analysis of solid propellants is generally done by the simplified governing equations for chemically inert condensed phase region with QSHOD assumption. Since the gas phase and surface reaction layer can be more rapidly relaxed to the external perturbations than the condensed phase, these regions are treated as quasi-steady manner in the analysis. In this paper, the classical ZN(Zeldovic-Novozhilov)approach was re-examined with the presence of radiation augmented burning enhancement in the combustion. Also, the surface reaction was assumed to partially absorb the incident radiant heat fluxes and pass the remaining to the chemically inert condensed phase. As a result of the analysis, the burning rate response function was obtained which consists of a pressure response function and a radiation response function. The response function was shown to be able to predict the results of T-burner tests.

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