• Asian Pacific Journal of Cancer Prevention
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• v.16 no.11
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• pp.4791-4795
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• 2015

Purpose: This study was conducted to observe the efficacy and safety of pemetrexed based chemotherapy in treating patients with locally advanced or metastatic cancers as first-line, second-line or third-line therapy. Materials and Methods: From May 2011 to January 2015, we recruited 29 patients with advanced breast cancer, 19 patients with advanced ovary cancer, 17 patients with advanced esophageal cancer,5 patients with advanced gallbladder cancer,5 patients with advanced cervical cancer and 1 patient with advanced tongue cancer in Jiangsu Cancer Hospital and Research Institute.All of them were pathologically confirmed and treated with pemetrexed based chemotherapy. After two cycles of treatment,efficacy and safety can be evaluated. Results: For pemetrexed based regimens,including 76 patients with 6 kinds of advanced cancer were considered eligible for inclusion. Complete remission represents CR, partial remission represents PR, stable disease represents SD, progressive disease represents PD. Among 29 patients with advanced breast cancer, 4 patients chose pemetrexed based regimens as second-line treatment,1 of them was PR,the other 3 got SD. The last 25 patients made use of this chemotherapy as third-line treatment, except one patient could not be assessed, 2 of them got PR,6 of them got SD,the remaining 16 of them finally were PD.19 patients with advanced ovary cancer,5 patients used this regimens as second-line treatment, 3 of them got PD,the remaining patients got SD, respectively. The last 14 patients made use of pemetrexed based regimens as third-line treatment,. RR (CR+PR) was 28.5%. Among 17 patients with advanced esophageal cancer, 2 patients made use of pemetrexed based regimens as first-line treatment,both of them got PR.4 of them used this chemotherapy as second-line regimen, except 2 patients could not be assessed,the remaining 2 was PD at last. The last 11 patients was third-line users, RR (CR+PR) was 18.2%. Among 5 patients with advanced gallbladder cancer, pemetrexed based regimens was used in 1 patient as first-line treatment and 1 patient as second-line treatment. The curative effect was SD and PD, respectively. 3 patients accepted pemetrexed based regimens as third-line treatment, 2 of them got PD as results and another was SD. Among 5 patients with advanced cervical cancer, just 1 patient adopted pemetrexed based regimens as first-line treatment, whose curative effect was PR.2 patients chose this chemotherapy regimens as second-line treatment. Both of them got PD as their consequence. The last 2 patients made use of the regimens as third-line treatment, the effect of them was PD and SD, respectively. The one who with advanced tongue cancer, pemetrexed based regimens was used as second-line treatment, and the consequence was PD. About 71.1% patients experienced bone marrow suppression. Among them, 5 patients reached 4 grade. Other toxicity of pemetrexed were neurotoxicity, fatigue, diarrhea, dysphagia and vomiting. No treatment related death occurred with pemetrexed-based treatment. Conclusions: Pemetrexed based chemotherapy has considerable effect in patients with advanced cancers such as breast cancer,esophageal cancer and ovary cancer. More randomly clinical trials are needed to verify the results.

• Journal of IKEEE
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• v.13 no.2
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• pp.181-185
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• 2009

In this paper, we are concerned with a 3D line segment extraction method by area-based stereo matching technique. The main idea is based on line fitting of elevation data on 2D line coordinates of ortho-image. Elevation data and ortho-image can be obtained by well-known area-based stereo matching technique. In order to use elevation in line fitting, the elevation itself should be reliable. To measure the reliability of elevation, in this paper, we employ the concept of self-consistency. We test the effectiveness of the proposed method with a quantitative accuracy analysis using synthetic images generated from Avenches data set of Ascona aerial images. Experimental results indicate that our method generates 3D line segments almost 7.5 times more accurate than raw elevations obtained by area-based method.

• Journal of Electrical Engineering and Technology
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• v.4 no.3
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• pp.330-336
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• 2009

This paper proposes an on-line voltage management and control solution for a distribution system which can improve the efficiency and accuracy of existing off-line work by collecting customer voltage on-line as well as the voltage compensation capability of the existing ULTC (Under Load Tap Changer) operation and control strategy by controlling the ULTC tap based on pattern clustering and recognition. The proposed solution consists of an ADVMD (Advanced Digital Voltage Management Device), a VMS (Voltage Management Solution) and an OLDUC (On-Line Digital ULTC Controller). An on-line voltage management emulator based on multi-thread programming and the shared memory method is developed to emulate on-line voltage management and digital ULTC control methodology based on the on-line collection of the customer's voltage. In addition, using this emulator, the effectiveness of the proposed pattern clustering and recognition based ULTC control strategy is proven for the worst voltage environments for three days.

• 제어로봇시스템학회:학술대회논문집
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• 2001.10a
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• pp.180.4-180
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• 2001

This paper describes a vision-based line-tracking system for AGV and steering control scheme. For detect the guideline quickly and exactly, We use four line-points which complement and predict each other. This low-cost line-tracking system is efficiently using PC-based real-time vision processing, Steering control is studied through an steering controller with guide-line angle and line-point error. This method is tested via a typical AGV with a single camera in laboratory environment.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.11
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• pp.4567-4570
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• 2014

Background: This systemic analysis was conducted to evaluate the efficacy and safety of pemetrexed based chemotherapy in treating patients with metastatic breast cancer as first or second line chemotherapy. Methods: Clinical studies evaluating the efficacy and safety of pemetrexed based regimens on response and safety for patients with breast cancer were identified using a predefined search strategy. Pooled response rate (RR) of treatment were calculated. Results: In first line pemetrexed based regimens, 10 clinical studies which including 513 patients with advanced breast cancer were considered eligible for inclusion. For second line pemetrexed based chemotherapy, 5 clinical studies which including 281 patients with advanced breast cancer were considered eligible. Systemic analysis suggested that, in all patients, pooled RR was 32.6% (167/513) in pemetrexed based first line regimens, and 13.9 % (39/281) in pemetrexed based second line regimens. Major adverse effects were neutropenia, leukopenia, fatigue, and anemia in pemetrexed based first line treatment; and lymphopenia, neutropenia, leukopenia, as well as anemia in second line chemotherapy. One treatment related death occurred with pemetrexed based second line treatment. Conclusion: This systemic analysis suggests that pemetrexed based first line regimens are associated with a reasonable response rate and acceptable toxicity, however with low response rate for treating patients with metastatic breast cancer when is used in the second line.

• Journal of the Korean Society of Clothing and Textiles
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• v.26 no.11
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• pp.1527-1576
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• 2002

Quick Response based Mass-Customization can be produced and distributed customized goods and services on mass basis in apparel e-business. Because consumers can: t touch and feel the apparel products in e-business, they tend to have the negative buying behavior. The purpose of this study is to investigate the differences of consumer's texture sensibility of apparel products based on marketing channels (on-line/off-line). Two types of questionnaires for on-line and of f-line were used to assess consumer sensibility on apparel fabric. The 8 swatches were selected in regard to the previous literatures. 205 questionnaires for each type (on-line/off-line) were distributed. Statistical devices were t-test, mean and standard deviation with SPSS10.0. The result of this study was showed that there were partially significant differences on consumers' texture sensibility on apparel products between on-line and off-line. Under on-line environment, consumers perceived corduroy as warm, strong, and sandy. taffeta as warm, sandy, and glossy, denim as sandy, and warm, organza as sandy, and thin, satin as sandy, dense, and modern, chiffon as sandy, and flat, velvet as warm, and soft, single jersey as warm, soft, and comfortable. Therefore, apparel firms cooperating based Mass-Customization in e-business have to pay attention to the differences on consumers’ texture sensibility of on-line apparel products from those of off-line.

• Journal of Korean Society of Transportation
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• v.24 no.2 s.88
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• pp.157-168
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• 2006

Spatial detection system such as AVI, GPS, and Beacon etc. can provide spatial travel time only after a vehicle Passes through a road section. In this context, majority of the existing studies on the link travel time estimation area has focused on the arrival time-based link travel time estimation. rather than departure time-based link travel time estimation. Even if some of the researches on this area have developed departure time-based link travel time estimation algorithms, they are limited in that they are not applicable in a real-time mode. The objective of this study is to develop an departure time-based link travel time estimation algorithm which is applicable in a real-tine mode. Firstly, this study discussed the tradeoff between accuracy and timeliness of the departure time-based on-line link travel time estimates. Secondly, this study developed an departure time-based on-line link travel time estimation algorithm which utilizes the Baysian inference logic. It was found that the proposed approach could estimate departure time-based link travel times in a real-time context with an acceptable accuracy and timeliness.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.67 no.6
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• pp.773-781
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• 2018

In recent years, a study of power-line inspection using an unmanned aerial vehicle (UAV) has been actively conducted. However, relevant studies have been conducting power-line inspection with an UAV operated by manual control, and they have developed just power-line detection algorithm on aerial images. To overcome limitations of existing research, we propose a drone-based power-line tracking system in this paper. The main contributions of this paper are to operate developed system under configured environment and to develop a power-line detection algorithm in real-time. Developed system is composed of the power-line detection and the image-based tracking control. To detect a power-line in real-time, a region of interest (ROI) image is extracted. Furthermore, clustering algorithm is used in order to discriminate the power-line from background. Finally, the power-line is detected by using the Hough transform, and a center position and a tilt angle are estimated by using the Kalman filter to control a drone smoothly. We design a position controller and an attitude controller for image-based tracking control, and both controllers are designed based on the proportional-derivative (PD) control method. The interaction between the position controller and the attitude controller makes the drone track the power-line. Several experiments were carried out in environments where conditions are similar to actual environments, which demonstrates the superiority of the developed system.

• Journal of Fisheries and Marine Sciences Education
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• v.21 no.2
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• pp.199-212
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• 2009

The purpose of this study is to analyze the cost-effectiveness analysis on on-line and off-line extra-curricula education(ECE). Based on a review of relevant literature, on-line ECE is defined as internet based learning, and off-line ECE is defined as on-site learning out of school such as private cram schools and private tutoring. The results of this study are as follows: First, sixty nine percent of the subjects were received ECE. Off-line ECE is more dominant than on-line ECE. Second, cost for off-line ECE is more expensive than on-line ECE. Third, off-line ECE is more effective than on-line ECE, when cost is ignored. Fourth, on-line ECE is more cost-effective than off-line ECE.

• Journal of Fashion Business
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• v.7 no.6
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• pp.85-91
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• 2003

Quick Response based Mass-Customization can be produced and distributed customized goods and services on mass basis in apparel e-business. Because consumers cannot touch and feel the apparel products in e-business, they tend to have the negative buying behavior. The purposes of this study were to analyze factors of texture image, and to investigate the differences of consumer sensibility on texture image of apparel products based on different marketing channels (on-line/off-line). Two types of questionnaires for on-line and off-line were used to assess consumer sensibility on apparel fabric. The 8 swatches were selected based on the previous literatures. 202 returned questionnaires for each type (on-line/off-line) were analyzed by t-test, mean and standard deviation with SPSS 10.0. The result of this study was showed that there were partially significant differences on consumer sensibility on texture image of apparel products between on-line and off-line. In case of corduroy, consumers perceived more high-class image under on-line than off-line. In case of taffeta, consumers perceived more thin and dense image under off-line (traditional marketing channel) than on-line (e-commerce). In case of denim, consumers perceived more thin and natural image under off-line than online. In case of organza, consumers perceived more natural image under on-line than off-line. In case of satin, consumers perceived more natural image under on-line than off-line. In case of chiffon, consumers perceived denser image under on-line than off-line. In case of velvet, consumers perceived thinner image, higher-class image, and more natural image of texture sensibility under on-line than off-line. In case of single jersey, consumers perceived higher-class image, and denser image of texture under on-line than off-line.