• Journal of Veterinary Clinics
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• v.4 no.2
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• pp.473-481
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• 1987

This experiment was performed in order to establish a proper method to determine the half life of indocyanine green(ICG T$\frac{1}{2}$) and its fractional clearance rate(KICG) and investigate the applicability of indocyanine green ( ICG ) excretion test in hepatotoxicity experiment in Korean black goats. The results were as follows : 1. Maximum absorbance of ICG in plasma was at 810 nm in this experiment. 2. The coefficient of correlation between the results obtained by standard method and potassium cyanide method was 0.99 and the regression equation between two methods was y=0.9996 x＋0.0065. 3. As the disappearance curve of ICG plotted in semi-log graph revealed linear pattern at least for 6 minutes after injection, the postinjection blood samples were decided to collect at 2 and 6 minutes after ICG injection. 4. ICG T$\frac{1}{2}$ and KICG values were not affected by dose level of ICG. 5. When 0.25 mg of ICG per kg body weight was administered the normal data of ICG T$\frac{1}{2}$ and KICG in Korean black goa were 1.468${\pm}$0.197 minutes(mean${\pm}$SD) and 0.482${\pm}$0.076/minutes respectively. 6. After administration of carbon tetracholride. the ICG T$\frac{1}{2}$ started to increase acutely from day 1, revealed the peak at day 3, and then returned almostly but not completely to preinjection level at day 14. The ICG T$\frac{1}{2}$ value was suggested to be a sensitive indicator of hepatic injury in Korean black goats.

• Journal of Internet Computing and Services
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• v.7 no.1
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• pp.91-99
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• 2006

This paper proposes a control path analysis mechanism to be used in the workflow mining framework maximizing the workflow traceability and re discoverability by analyzing the total sequences of the control path perspective of a workflow model and by rediscovering their runtime enactment history from the workflow log information. The mechanism has two components One is to generate the total sequences of the control paths from a workflow mode by transforming it to a control path decision tree, and the other is to rediscover the runtime enactment history of each control path out of the total sequences from the corresponding workflow's execution logs. Eventually, these rediscovered knowledge and execution history of a workflow model make up a control path oriented intelligence of the workflow model. which ought to be an essential ingredient for maintaining and reengineering the qualify of the workflow model. Based upon the workflow intelligence, it is possible for the workflow model to be gradually refined and finally maximize its qualify by repeatedly redesigning and reengineering during its whole life long time period.

• Food Science of Animal Resources
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• v.36 no.1
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• pp.90-99
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• 2016

This study evaluated the effects of two Korean traditional plant extracts (Diospyros kaki THUNB. leaf; DK, and Nelumbo nucifera leaf; NN) on the fermentation, functional and sensory properties of herbal yogurts. Compared to control fermentation, all plant extracts increased acidification rate and reduced the time to complete fermentation (pH 4.5). Supplementation of plant extracts and storage time were found to influence the characteristics of the yogurts, contributing to increased viability of starter culture and phenolic compounds. In particular, the increase in the counts of Streptococcus thermophilus and Lactobacillus delbrueckii subsp. bulgaricus was highest (2.95 and 1.14 Log CFU/mL respectively) in DK yogurt. Furthermore, supplementation of the plant extracts significantly influenced to increase the antioxidant activity and water holding capacity and to produce volatile compounds. The higher antioxidant activity and water holding capacity were observed in NN yogurt than DK yogurt. Moreover, all of the sensory characteristics were altered by the addition of plant extracts. Addition of plant extracts increased the scores related to flavor, taste, and texture from plain yogurt without a plant extract, as a result of volatile compounds analysis. Thus, the overall preference was increased by plant extracts. Consequently, supplementation of DK and NN extracts in yogurt enhanced the antioxidant activity and physical property, moreover increased the acceptability of yogurt. These findings demonstrate the possibility of using plant extracts as a functional ingredient in the manufacture of herbal yogurt.

• Proceedings of the Korean Society for Applied Microbiology Conference
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• 2000.04a
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• pp.53-60
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• 2000

Strain BH5 was isolated from naturally fermented Kimchi and identified as a bacteriocin producer, which has bactericidal activity against Micrococcus flavus ATCC 10240. Strain BH5 was identified tentatively as Lactococcus lactis by the API test and some characteristics. Lactococcus lactis BH5 showed a broad spectrum of activity against most of the non-pathogenic and pathogenic microorganisms tested by the modified deferred method. The activity of lacticin BH5, named tentatively as the bacteriocin produced by Lactococcus lactis BH5, was detected at the mid-log growth phase, reached its maximum during the early stationary phase, and decreased after the late stationary phase. Lacticin BH5 also showed a relatively broad spectrum of activity against non-pathogenic and pathogenic microorganisms as tested by the spot-on-lawn method. Its antimicrobial activity on sensitive indicator cells was completely disappeared by protease XIV or ${\alpha}$-chymotrypsin. The inhibitory activities of lacticin BH5 were detected during treatments up to 100$^{\circ}C$ for 30 min. Lacticin BH5 was very stable over a pH range of 2.0 to 9.0 and was stable with all the organic solvents examined. The cell concentration and bacteriocin production in strain BH5 were maximum when grown at 30$^{\circ}C$ in a modified MRS medium supplemented with 0.5% tryptone, 1.0% yeast extract, and 0.5% beef extract as nitrogen sources. It demonstrated a typical bactericidal mode of inhibition against Micrococcus flavus ATCC 10240. Lacticin BH5 was purified through ammonium sulfate precipitation, ethanol precipitation, and CM-Sepharose column chromatography. The apparent molecular mass of lacticin BH5 was estimated to be in the region of 3.7 kDa, by the direct detection of bactericidal activity after SDS-PAGE. Mutant strain NO141 which was isolated by nitrosoguanidine mutagenesis produced about 4 fold more bacteriocin than the wild type.

• Journal of the Korean Wood Science and Technology
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• v.36 no.5
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• pp.42-48
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• 2008

This study was conducted to discuss the effects of hardener and extender contents on peak temperature, reaction enthalpy (${\Delta}H$), gelation time, viscosity change, and pH value in three types of UMF (urea-melamine- formaldehyde) resin with the help of perpHecT LogR meter, differential scanning calorimetry (DSC), and advanced rheometric expansion system (ARES), The results indicated that the pH value of Control A steeply decreased to 5,2 in the early stage but relatively remained constant thereafter as in Synthesis 1 and Synthesis 2, The peak temperature and time decreased as well, whereas ${\Delta}H$ and viscosity increased with the increase of hardener content. On the other hand, ${\Delta}H$ was not changed up to the extender content of 5% and then decreased with its further addition, And the pH value and peak temperature showed no change with the increase of extender content at the hardener content of 5% in three types of UMF resin, The effect of hardener content in this experiment, however, appeared more conspicuous in Control A than in the other two types of Synthesis 1 and Synthesis 2, These results might be caused by higher molecular weight with longer chains of methylene ($-CH_2-$) and methylene ($-CH_2-O-CH_2-$) ether bridges or much more branched chains in Control A.

• Journal of the Society of Naval Architects of Korea
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• v.30 no.4
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• pp.153-168
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• 1993

The ship sailing among waves suffers from the various wave loads that comes from its motion throughout its life. In the rationally-based design, the dynamic structural analysis is carried out using dynamic wave loads provided from the results of the ship motion calculation as the rigid body. This method is based on the linear theory assumed low wave height and small amplitude of motion. But at the rough sea condition, relatively high wave compared to the height ship's depth is induced the large ship motion, so configuration of the ship section below waterline changes rapidly at each time. This re-sults in a non-linear problem. Considering above situation we have already introduced the non-linear dynamic strength analysis method for the hull girder(refer vol. 29. No.4 November, 1992, Journal of SNAK). In this paper, estimation of the hull girder strength for various ship types such as tankers, containers and log carriers is carried out based on the introduced non-linear method. We expect that the results will be used as useful basic data for the es-timation of dynamic strength of ships in the rough sea.

• Journal of Periodontal and Implant Science
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• v.45 no.1
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• pp.23-29
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• 2015

Purpose: This study was conducted to compare the cumulative survival rates (CSRs) and the incidence of postloading complications (PLCs) between a bone-level internal connection system (ICS-BL) and an external connection system (ECS). Methods: The medical records of patients treated with either a ICS-BL or ECS between 2007 and 2010 at Asan Medical Center were reviewed. PLCs were divided into two categories: biological and technical. Biological complications included >4 mm of probing pocket depth, thread exposure in radiographs, and soft tissue complications, whereas technical complications included chipping of the veneering material, fracture of the implant, fracture of the crown, loosening or fracture of the abutment or screw, loss of retention, and loss of access hole filling material. CSRs were determined by a life-table analysis and compared using the log-rank chi-square test. The incidence of PLC was compared with the Pearson chi-squared test. Results: A total of 2,651 implants in 1,074 patients (1,167 ICS-BLs in 551 patients and 1,484 ECSs in 523 patients) were analyzed. The average observation periods were 3.4 years for the ICS-BLs and 3.1 years for the ECSs. The six-year CSR of all implants was 96.1% (94.9% for the ICS-BLs and 97.1% for the ECSs, P=0.619). Soft tissue complications were more frequent with the ECSs (P=0.005) and loosening or fracture of the abutment or screw occurred more frequently with the ICS-BLs (P<0.001). Conclusions: Within the limitations of this study, the ICS-BL was more prone to technical complications while the ECS was more vulnerable to biological complications.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.22 no.1
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• pp.49-53
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• 2018

In the recent years, an attempts have been made to convergence medical technology and IT technology to overcome the limitations of temporal, spatial in the medical technology applications. Emergency care is primarily intended to provide primary care and stabilization to the patient, thereby saving the patient's life and minimizing the risk until hospital care. In this study, we developed an application S/W to support emergency services for emergency medical services. Paramedics can easily keep a log of emergency activities and monitor the patient's condition in real time with this application S/W on smart devices. In particular, medical signals and information emergency status of emergency patients can be measured or photographs of affected areas can be taken. In addition, this report can be delivered to remote medical doctors for rapid emergency measures and immediate hospital response.

• Archives of Pharmacal Research
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• v.29 no.8
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• pp.707-711
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• 2006

Bifidobacteria-loaded alginate poly-l-lysine microparticles (bap microparticles) were prepared using an air atomization method and then freeze-dried. The viability of the bap microparticles was investigated as a function of the amount of the bifidobacteria cultures, and the addition of a yeast extract, cryoprotectants, antioxidants and neutralizer. The size of the bap microparticles with and without the bifidobacteria was $84.8{\pm}28.5\;{\mu}m$ ($mean{\pm}standard$ deviation) and $113.1{\pm}38.5\;{\mu}m$, respectively. The surface morphology was slightly ellipsoid and wrinkled regardless of the incorporating bifidobacteria. The viability gradually decreased with increasing freeze-drying time. Free-flowing powdered bap microparticles were obtained at least 12 h after freeze-drying the wetted slurry of bap microparticles. However, the particles tended to aggregate when either lactose or ascorbic acid was added. The addition of a yeast extract, cryoprotectants (glycerol and lactose), antioxidants ($NaHSO_3$ and ascorbic acid) and neutralizer $(Mg_3(PO_4)_2)$ resulted in a significantly higher viability of the bifidobacteria in the bap microparticles after freeze-drying (0.34-1.84 log) compared with the culture alone.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.23 no.8
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• pp.942-949
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• 2012

In order to ensure the safety of the large-scale public facilities, the analysis of EMC(ElectroMagnetic Compatibility) of electronic systems included in the facilities is very necessary. The reason is that the system-level EMC of the facility could be not guaranteed, even if individual equipments included in the facility are satisfied with their EMC requirements. As a result, the system-level evaluation and analysis of EMC should be carried out in order to establish the reliable operations of safety and mission-critical electronic systems. This paper analyze the relevant legal systems of domestic and other countries, and furthermore case studies of system-level EMC approaches were analyzed in the specific applications of electric railways, building, automobile, petroleum refinery systems. And the introduction of related systems in Korea is proposed, and main parts and problems to be looked at each proposed measures are discussed. The results are expected to be utilized in the introduction of the system-level EMC engineering, and contributed in national security and the protection of people's life, body and their properties.