• Title/Summary/Keyword: Life and Death

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Literary Physiology of an Emotional Ratio Using Sijo (시조를 활용한 감정 비율의 문학생리학)

  • Park, Inkwa
    • The Journal of the Convergence on Culture Technology
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    • v.5 no.2
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    • pp.305-311
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    • 2019
  • Does the healing of life lead to a grave, or can death heal life? The healing in life exists in the emotional circuit of the space of life. So what kind of space does healing in death exist? For now, healing in death exists beyond life. Imje (林悌, 1549-1587) is famous for reciting Sadness Sijo in his beloved Hwang Jin-yi's Grave. For the Literature Therapy, this time we're trying to code the Emotions of Sijo "The Valley Which is Covered With Blue Grass", which Imje is said to have recited in the Hwang Jin-yi's Grave. This Sijo sings the love of Sadness such as Love and Death, Grave and Sadness. That is, how fuse human Emotions, which are caused by conflicting concepts of love and pain or love and separation. Imje's Sijo fuses signifiers such as Grave, Love and Sadness to code 'The Transience of Human Life.' This 'The Transience of Human Life' is a function of this Sijo's Literature Therapy. 'The Transience of Human Life' has a role of healing that relaxes the human body. With the Literature Therapy in place like this, no matter how painful life is, we have some leeway. This is because the sadness of 'The Transience of Human Life' delivered by Sijo conveys the effect of the Literature Therapy, which contemplate and tolerate the entire life. We look forward to continuing this research and achieving Emotion Coding for new life.

Effects of Death Preparation Education on Awareness of Hospice Palliative Care and Withdrawing Life Sustaining Treatment in City Dwellers (죽음준비교육이 일반인의 연명치료중단 및 호스피스·완화의료에 대한 인식에 미치는 효과)

  • Tsung, Pei-Ling;Lee, Yoon Joo;Kim, Su Yeon;Kim, Seul Ki;Kim, Si Ae;Kim, Hyeon Ji;Nam, Yi;Ham, Suk Young;Kang, Kyung Ah
    • Journal of Hospice and Palliative Care
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    • v.18 no.3
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    • pp.227-234
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    • 2015
  • Purpose: This study was done to analyze how a death preparation education program have the effects on awareness of hospice palliative care and withdrawing life sustaining treatment in older adults. Methods: This study employed a non-equivalent control group design among quasi-experimental designs. The experimental group was comprised with 35 adults and the control group with 40 adults. The death preparation program consisted of five two-hour sessions and was administered once a week for five straight weeks. Data were analyzed by descriptive statistics, t-test, ${\chi}^2$ test, Fisher's exact test, and ANCOVA using SPSS version 18.0. Results: The mean age of the participants was 66.2 years. A significant difference between the experimental and control groups was observed in withdrawing life sustaining treatment (F=3.380, P=0.040). However, no significant difference was found in awareness of hospice palliative care (F=0.163, P=0.850). Conclusion: The study results indicate that death preparation training could positively affect people's awareness of withdrawing life sustaining treatment. More studies should be conducted to explore effects of death preparation education for all ages and help people better understand hospice palliative care.

TRAP1 regulation of mitochondrial life or death decision in cancer cells and mitochondria-targeted TRAP1 inhibitors

  • Kang, Byoung-Heon
    • BMB Reports
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    • v.45 no.1
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    • pp.1-6
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    • 2012
  • Hsp90 is one of the most conserved molecular chaperones ubiquitously expressed in normal cells and over-expressed in cancer cells. A pool of Hsp90 was found in cancer mitochondria and the expression of the mitochondrial Hsp90 homolog, TRAP1, was also elevated in many cancers. The mitochondrial pool of chaperones plays important roles in regulating mitochondrial integrity, protecting against oxidative stress, and inhibiting cell death. Pharmacological inactivation of the chaperones induced mitochondrial dysfunction and concomitant cell death selectively in cancer cells, suggesting they can be target proteins for the development of cancer therapeutics. Several drug candidates targeting TRAP1 and Hsp90 in the mitochondria have been developed and have shown strong cytotoxic activity in many cancers, but not in normal cells in vitro and in vivo. In this review, recent developments in the study of mitochondrial chaperones and the mitochondria-targeted chaperone inhibitors are discussed.

The study on the view of death in the Buddhism for well dying's culture formation (웰다잉(well dying) 문화 형성을 위한 불교의 죽음관 연구)

  • Yun, Young-ho
    • Journal of Korean Philosophical Society
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    • v.130
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    • pp.161-186
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    • 2014
  • Recently, the social concerns on well dying come to the fore as important discourse on dignity of human death, which detonation by the problem of euthanasia. Well dying means 'good death' the meaning of a word, and it means 'prepared death', 'decented death' 'beautiful death' by extention of sematic context like this as a general rule. In this paper the writter have considered that how the view of Buddhism's death contribute to the discourse on well dying, which regarding death as the starting point, death conquest as the finishing point of the theory. The Buddhism's discourse on the attitude interpretation conquest process of death contributed to formation of abundant discourse on well dying, especially the view of Buddhism is able to contribute to conquest of death anxiety and death education, that death conquest interpret to spiritual psychological phenomenon not physical physiological eternal life (or immortality) and conquer death through enlightenment on reality of things by spiritual psychological change.

Rice 7-Hydroxymethyl Chlorophyll a Reductase Is Involved in the Promotion of Chlorophyll Degradation and Modulates Cell Death Signaling

  • Piao, Weilan;Han, Su-Hyun;Sakuraba, Yasuhito;Paek, Nam-Chon
    • Molecules and Cells
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    • v.40 no.10
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    • pp.773-786
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    • 2017
  • The loss of green coloration via chlorophyll (Chl) degradation typically occurs during leaf senescence. To date, many Chl catabolic enzymes have been identified and shown to interact with light harvesting complex II to form a Chl degradation complex in senescing chloroplasts; this complex might metabolically channel phototoxic Chl catabolic intermediates to prevent oxidative damage to cells. The Chl catabolic enzyme 7-hydroxymethyl Chl a reductase (HCAR) converts 7-hydroxymethyl Chl a (7-HMC a) to Chl a. The rice (Oryza sativa) genome contains a single HCAR homolog (OsHCAR), but its exact role remains unknown. Here, we show that an oshcar knockout mutant exhibits persistent green leaves during both dark-induced and natural senescence, and accumulates 7-HMC a and pheophorbide a (Pheo a) in green leaf blades. Interestingly, both rice and Arabidopsis hcar mutants exhibit severe cell death at the vegetative stage; this cell death largely occurs in a light intensity-dependent manner. In addition, 7-HMC a treatment led to the generation of singlet oxygen ($^1O_2$) in Arabidopsis and rice protoplasts in the light. Under herbicide-induced oxidative stress conditions, leaf necrosis was more severe in hcar plants than in wild type, and HCAR-overexpressing plants were more tolerant to reactive oxygen species than wild type. Therefore, in addition to functioning in the conversion of 7-HMC a to Chl a in senescent leaves, HCAR may play a critical role in protecting plants from high light-induced damage by preventing the accumulation of 7-HMC a and Pheo a in developing and mature leaves at the vegetative stage.

Attitudes Toward Legalization of Death with Dignity (존엄사의 법제화에 대한 태도)

  • Kim, Mee-Hye;Kim, So-Hee
    • The Journal of the Korea Contents Association
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    • v.10 no.10
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    • pp.304-317
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    • 2010
  • The purpose of this study is to research on attitudes toward legalization of death with dignity. The respondents are 561 adults aged 20 years old and over, living in Seoul and Kyunggi Province. Research questionnaire consist of 28 questions concerning general background, personal experiences of death, attitudes toward death, pros and cons on death with dignity and legalization. Statistical analyses employ frequency, mean, cross tab, and t-test. 87.3% of respondents agree the legalization of death with dignity. The persons who are older, self-employed, and production employees, get married, live with spouse, believe buddhism, experience care for the death, believe life after death, recognize the necessity of testament agree more on death with dignity. The first requisite for legalization of death with dignity is the standard of judgement concerning self decision on death with dignity. The decision makers are prioritized by self, family member in order. The necessary services for decisions on death with dignity are the mediation role between medical team and family, medical information about illness prognosis and prolongation, psychological counselling on depression.

The coping Process to the death Spouse among Middle and Old-Aged Widows; The Moderating Effect of Social Support and Self-Complexity (중.노년기 여성의 배우자사망에 대한 적응:사회적 지지와 자기복합성의 중재적 효과)

  • 최혜경
    • Journal of Families and Better Life
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    • v.16 no.3
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    • pp.1-10
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    • 1998
  • The study attempts to examine the moderating effects of social support and self-complexity in coping to the death of spouse among middle and old-aged widows. The important findings from the data based on the sample of 161 widows are (1) age differentiates the types of stress experienced by widows (2) social support and self-complexity may either buffer or intensify depending on the circumstances in which widows reside in the negative effects of stress on psychological health among widows and (3) the moderating role of social support and self-complexity differs according to age of widows with older widows being more affected by these coping resources The results of the study support the assumptions drawn from Life-Course Perspective to explain the coping process to the death of spouse.

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The Impact of Nursing Hospital Workers' Hospice·Palliative Care Knowledge and Awareness, End-of-Life Care Attitude and Death Awareness on Their End-of-Life Care Performance (요양병원 근무자의 호스피스 완화돌봄 지식과 인식, 임종돌봄 태도, 죽음에 대한 인식이 임종돌봄 수행에 미치는 영향)

  • Park, Meera;Je, Nam Joo
    • Journal of Hospice and Palliative Care
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    • v.21 no.4
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    • pp.124-136
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    • 2018
  • Purpose: This descriptive study is aimed at identifying how nursing hospital workers' performance of end-of-life care is influenced by their knowledge and awareness of hospice palliative care, attitude towards end-of-life care, performance, importance, awareness of death and the factors. Methods: A self-reported questionnaire was used to collect data from 113 workers at an accredited nursing hospital in K province. Variables were their knowledge and awareness of hospice palliative care, attitude towards end-of-life care, end-of-life care performance and importance and awareness of death. An analysis was performed with the frequency, percentage, mean, standard deviation, t-test, ANOVA, Scheffe's test, Pearson's correlation coefficient and multiple regression using IBM SPSS 21.0. Results: The factors affecting the nursing hospital workers' end-of-life care performance were the importance of end-of-life care and their marital status, which showed an explanatory power of 38.2%. Conclusion: In order to improve the nursing hospital workers' end-of-life care performance, a training on the importance of end-of-life care should be provided. Therefore, we would like to propose establishing administrative measures such as 1) efficient staffing to help the caregivers better perform what they think is important, 2) development of a training program that can improve their performance of end-of-life nursing care and 3) a study to verify the effectiveness of the program.

The Cyclical Structure of "Life and Death" in "Snowstorm-Plot" Reflected in "Snowstorm" of M.A. Bulgakov ("눈보라 슈제트"에 구현된 삶-죽음의 순환구조: M.불가코프 단편 「눈보라(Вьюга)」를 중심으로)

  • Kang, Su Kyung
    • Cross-Cultural Studies
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    • v.23
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    • pp.7-32
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    • 2011
  • In this article, we tried to introduce a little-known work of M.A. Bulgakov "Snowstorm" and provide some various clues for reading this short story. This study is focused on "snowstorm-plot", grasping the structure and the theme of the present work. To this end, in the Chapter II we tired to seek for the meanings of Bulgakov's "snowstorm" based on intertextuality shown from the works by those writers such as Pushkin, Gogol and Tolstoy. In this short story "snowstorm" is presented not only as a natural phenomenon but as a "participant" which provides young doctor-narrator with short time break and let him go to a dying bride, and at last place him on the crossroads of life and death. Indeed "snowstorm" plays a role of the framed structure of Bulgakov's text. In the Chapter III we observed the creative expression of Bulgakov's work which is comprised of overlappings with dream and reality. In other words, in the short story "Snowstorm" the outside and the inside story of frame are described as a dream of the one same night. We can guess that the Shermetievo story is a kind of dream of young doctor who fell asleep in Tuesday night, asking himself "how many patients will come tomorrow?". By the way the Shermetievo story unfolds as an incident which is happened on Wednesday. In this way in Bulgakov's "Snowstorm" it is hard to draw clear lines of demarcation between dream and reality. Therefore existential themes like these "Life and Death", "Professional calling and personal conscience", "The great nature and the week human being" are resonated with original structure "Dream in Dream".

Prototypical Eye Shape Classification to Solve Life-and-Death Problem in Go, using Monte-Carlo Method and Point Pattern Matching (몬테카를로 방법과 점 패턴 매칭을 활용한 바둑에서의 사활문제 해결을 위한 원형 안형의 분류)

  • Lee, Byung-Doo
    • Journal of Korea Game Society
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    • v.21 no.6
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    • pp.31-40
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    • 2021
  • Go has a history of more than 2,500 years, and the life-and-death problems in Go is a fundamental problem domain that must be solved when implementing a computer Go. We attempted to determine the numbers of prototypical eye shapes with 3, 4, 5, and 6 eyes that are directly related to the life-and-death problems, and to classify the prototypical eye shapes represented in 4-tuple forms. Experiment was conducted by Monte-Carlo method and point pattern matching. According to the experimental results, the numbers of prototypical eye shapes were 2 for 3-eye, 5 for 4-eye, 12 for 5-eye, and 35 for 6-eye shapes. Further, using a 4-tuple form, we classified prototypical eye shapes into 1 for 3-eye, 3 for 4-eye, 4 for 5-eye, and 8 for 6-eye shapes.