• International Journal of Internet, Broadcasting and Communication
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• v.12 no.3
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• pp.74-86
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• 2020

This study discussesresearch and development of large-sized 3D printers that can be applied to construction and civil engineering for various designs of protective casing on foam liner for concrete exteriors. The consistent use of concrete represents the current surroundings. However, concrete exteriors in Korea have not considered the regional characteristics, but the concrete has been poured solely for economical aspects for the last decade or two. There are many cases of poor installation and not enough design development projects to correct it. This study was conducted to apply various patterns, regional characteristics, and 3D printing for protective casing design for foam liner to create various designs for the concrete walls. Therefore, we started researching on a large 3D printer, and designed and developed this system. Considering the chronological process, the properties of concrete structures were identified, the application of designs for concrete in Korea and abroad and the 3D printing materials for the protective casing were surveyed and analyzed, and a stereotype was produced in the first year to study designs for the beauty of concrete surfaces. In the second year, images of regional characteristics were gathered, design ideas for regional promotion were derived, virtual images were produced along with design modeling to simulate the appearances, and verify the effect of application and promotion. Finally, in the third year, the 3D printer for concrete foam liner was constantly improved to analyze the 3D printing program and the various library elements to complete an actual large-sized 3D printer.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.5
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• pp.2499-2506
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• 2016

Background: Gastric cancer (GC) is the second leading cause of cancer-related death worldwide. Several environmental, genetic and epigenetic factors have been suggested to have a role in GC development. Epigenetic mechanisms like histone changes and promoter hyper-methylation are now being increasingly studied. Associations between methylation of many gene promoters with the risk of gastric cancer have been investigated worldwide. Such aberrant methylation may result in silencing of specific genes related to cell cycling, cell adhesion, apoptosis and DNA repair. Thus this molecular mechanism might have a key role in proliferation and migration of cancerous cells. Materials and Methods: In this review article we included studies conducted on DNA methylation and gastric cancer in Iranian populations. Using Science direct, Pubmed/PMC, Springer, Wiley online library and SciELO databases, all published data until 31 January 2016 were gathered. We also searched Science direct data base for similar investigations around the world to make a comparison between Iran and other countries. Results: By searching these databases, we found that the association between methylation of seven gene promoters and gastric cancer had been studied in Iran until 31 January 2016. These genes were p16, hLMH1, E-cadherin, CTLA4, $THR{\beta}$, mir9 and APC. Searching in science direct database also showed that 92 articles had been published around the world till January 2016. Our investigation revealed that despite the importance of GC and its high prevalence in Iran, the methylation status of only a few gene promoters has been studied so far. More studies with higher sample numbers are needed to reveal the relation of methylation status of gene promoters to gastric cancer in Iran. Conclusions: Further studies will be helpful in identifying associations of DNA methylation in candidate genes with gastric cancer risk in Iranian populations.

• Smart Structures and Systems
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• v.22 no.5
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• pp.575-586
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• 2018

Computational Building Information Modeling (BIM) is an intelligent 3D model-based process that provides architecture, engineering, and construction professionals the insight to plan, design, construct, and manage buildings and infrastructure more efficiently. This paper aims at using BIM in Hospitals configurations protection. Infrastructure projects are classified as huge structural projects taking advantage of many resources such as finance, materials, human labor, facilities and time. Immense expenses in infrastructure programs should be allocated to estimating the expected results of these arrangements in domestic economy. Hence, the significance of feasibility studies is inevitable in project construction, in this way the necessity in promoting the strategies and using global contemporary technologies in the process of construction maintenance cannot be neglected. This paper aims at using the building information modeling in covering Imam Khomeini Hospital's equipment. First, the relationship between hospital constructions maintenance and repairing, using the building information modeling, is demonstrated. Then, using library studies, the effective factors of constructions' repairing and maintenance were collected. Finally, the possibilities of adding these factors in Revit software, as one of the most applicable software within BIM is investigated and have been identified in some items, where either this software can enter or the software for supporting the repairing and maintenance phase lacks them. The results clearly indicated that the required graphical factors in construction information modeling can be identified and applied successfully.

• Journal of the Korean Society for information Management
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• v.22 no.4 s.58
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• pp.111-128
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• 2005

University libraries have been facing challenges to accomplish both roles of traditional libraries as physical places and virtual libraries which service electronic resources effectively. University libraries need to establish a strategic plan as a positive tool for designing the future of university libraries addressing threats and opportunities at the same time. This study suggested the core elements be involved in strategic plans of university libraries through comparatively analyzing the actual documents of strategic plans of academic libraries in America, England, Canada and Australia. These strategic plans were divided into formal elements and content elements. In addition, this study presented the latest strategic plans of academic libraries such as UMI. OULS, UBCL, and USL. As a result of research, this study provided the directions and basic materials in order to establish strategic planning at university libraries in Korea.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.38
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• pp.2.1-2.9
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• 2016

Background: We reviewed the biological and mechanical properties of porous hydroxyapatite (HA) compared to other synthetic materials. Computer-aided design/computer-aided manufacturing (CAD/CAM) was also evaluated to estimate its efficacy with clinical and radiological assessments. Method: A systematic search of the electronic literature database of the National Library of Medicine (PubMed-MEDLINE) was performed for articles published in English between January 1985 and September 2013. The inclusion criteria were (1) histological evaluation of the biocompatibility and osteoconductivity of porous HA in vivo and in vitro, (2) evaluation of the mechanical properties of HA in relation to its porosity, (3) comparison of the biological and mechanical properties between several biomaterials, and (4) clinical and radiological evaluation of the precision of CAD/CAM techniques. Results: HA had excellent osteoconductivity and biocompatibility in vitro and in vivo compared to other biomaterials. HA grafts are suitable for milling and finishing, depending on the design. In computed tomography, porous HA is a more resorbable and more osteoconductive material than dense HA; however, its strength decreases exponentially with an increase in porosity. Conclusions: Mechanical tests showed that HA scaffolds with pore diameters ranging from 400 to $1200{\mu}m$ had compressive moduli and strength within the range of the human craniofacial trabecular bone. In conclusion, using CAD/CAM techniques for preparing HA scaffolds may increase graft stability and reduce surgical operating time.

• Journal of the Korean housing association
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• v.23 no.6
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• pp.49-59
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• 2012

This study suggested a new model in consideration of long life and constructability of apartment house suggested in the former part. New model suggested the possibility of cost saving based on the idea that people trend to reject because of the recognition that the new model would cost a lot of expense which work as the barrier for the expansion and distribution at the local market so as to prepare the ground for its activation. The Study was aimed at verifying the possibility of cost saving through comparing it with the existing standard apartment house system centered on the skeleton and cladding system among the new structural design models suggested in the former part. Assuming that these existing standard both models should be changed structural design into new model system, the quantity volume, cost and construction period along with the alteration of finished materials between two models were compared altogether. Simultaneously BIM library was built for easy taking-off bill of quantity and consideration of working methodology for construction working cycle, which was translated into construction cost so as to derive the cost of the two subject systems to be counted. Through the analysis, it was concluded that new model would secure variability in the future and constructability along with shortening the construction period (29%) and achieve cost saving (13%) of construction against the those of existing model.

• The Journal of Korean Medicine
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• v.31 no.4
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• pp.49-62
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• 2010

Objectives: Current information & communication technology is advancing very rapidly and the ripple effects are spreading all over society traditional Korean medicine (TKM) is no exception. We draw up afuture plan and target system's architecture of KIOM's OASIS to follow the information change and reinforce the supporting infra for TKM research. Methods: First, we analyzed the information circumstances of western and eastern medicine, both overseas and domestic, especially investigating the detailed changes domestically. Second, we grasped the present conditions of OASIS and compared it with other information portals. Finally, we drew a future plan and system architecture from the analysis results. Results: First, the information status of western medicine is much more advanced than TKM's, and overseas information circumstances are likewise more developed than domestics. Second, we found that OASIS is performing the central research infra role well in TKM. Finally we designed an information system architecture which is composed of an infra layer, an application layer and a service layer. Conclusion: We must integrate information materials such as literature, research manpower, facilities and standards to make TKM's knowledge portal successful. In detail, we have to make TKM's information classification code, build up the electronic TKM library and offer complementary and alternative medicine (CAM) trends.

• Proceedings of the KSAR Conference
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• 2003.06a
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• pp.97-97
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• 2003

For many animals the centrosome consists of a pair of centrioles and surrounding pericentriolar materials (PCMs). PCMs have been known to play roles during cell division. It is known that centrioles are necessary to assemble centrosomal components. However, many types of oocytes undergo meiosis without centrioles. It is known that in nonmurine mammalian species, the sperm introduces an intact proximal centriole unlike sea urchin where two centrioles are introduced. In case of mouse sperm, the presence of centrosome is not clear In this study, a monoclonal antibody was developed to investigate centrosome during mouse germ cell and early embryo development. Results of immunostaining and Western blotting in CHO cells suggest that the monoclonal antibody recognizes a nuclear and centrosomal protein, thus called NCP. The NCP monoclonal antibody was used to screen a cDNA expression library prepared from 12.5 mouse brain to isolate NCP gene. Nucleotide size of NCP gene obtained from immunoscreening was about 5.5kb. It is determined that the NCP may be closely related with pericentriolar material -1 gene (Pcm-1) from the result of sequencing analysis. The molecular weight, 66kDa, calculated by known DNA sequence in database is consistent with that of detected from Western blotting using CHO cell lysates. Therefore, it is assumed that NCP may be alternative splicing form of Pcm-1 of which molecular weight is 228kDa. In mouse oocytes, NCP was distributed in nucleus as in CHO cells. It was shown that the NCP was localized around neck region, probably the centrosome in mouse neck region. Interestingly, dramatic change in distribution of NCP was also shown in male germ cell development. Finally, we observed the cellular distribution of NCP during early embryo development. NCP was detected in nucleus as well as centrosome foci. It is suggested that the centrioles reassembly we occurring in blastocysts and then affects the distribution of NCP.

• Archives of design research
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• v.11 no.3
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• pp.79-88
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• 1998

This research was carried out with emphasis on merits of computers as an education medum. Network technologies make collaboration as easy as they work in the same space. It is generally considered that education should be done with adequate contents and effective methods. But, the methods used in computer graphics education are not different from others, and this fact makes a low efficiency. To improve the education environments, design education program is developed. This is designed on the basis of LAN, and partially on the web. The library where design materials for study are stored and the gallery where design works done by students are exhibited are modules that utilize web technologies. Communication between students will become easy by using whiteboard and feedback from various kinds of user will be done by uploading design works on the web. But the program can be used only in the computer oriented subjects now, so further study should be carried out to broaden the scope of design education.

• Journal of the Korean Society for information Management
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• v.21 no.2
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• pp.45-67
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• 2004

The purposes of this study are to compare and analyze the evaluation indicators for selection of journal suggested by scholars and organizations and to prepare theoretical background for the ideal model to meet opposing paradigms of collection management in academic libraries. A web survey method was employed to investigate applications of various selection criteria (27 for printed and 37 for electronic academic Journal) from the top 40 academic libraries in Korea. In addition, data were analysed statistically using factor analysis, t-test, Analysis of Variance(ANOVA), and Spearman's Rank Oder Correlation. The mean ranking for 9 evaluation indicators for printed were as follows: subscribing volumes per departments, degree of use, selection authority, electronic/print bundle, ISI impact factor, Internationality and reputation, costs for subscription, ILL ＆ DDS, space considerations for printed materials. But, 11 evaluation indicators for electronic were as follows : costs for subscription, accessibility, electronic/print bundle, consortia, selection authority, access expandability, subscribing volumes per departments, scholarly features of the university, ISI impact factor, ILL ＆ DDS, internationality and reputations.