• 한국운동역학회지
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• 제28권2호
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• pp.101-108
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• 2018

Objective: The aim of this study was to investigate gender differences in ground reaction force (GRF) components among different speeds of running. Method: Twenty men ($age=22.4{\pm}1.6years$, $mass=73.4{\pm}8.4kg$, $height=176.2{\pm}5.6cm$) and twenty women ($age=20.7{\pm}1.2years$, $mass=55.0{\pm}8.2kg$, $height=163.9{\pm}5.3cm$) participated in this study. All participants were asked to run on an instrumented dual belt treadmill (Bertec, USA) at 8, 12, and 16 km/h for 3 min, after warming up. GRF data were collected from 30 strides while they were running. Hypotheses were tested using one-way ANOVA, and level of significance was set at p-value <.05. Results: The time to passive peaks was significantly earlier in women than in men at three different running speeds (p<.05). Further, the impact loading rates were significantly greater in women than in men at three different running speeds (p<.05). Moreover, the propulsive peak at 8 km/h, which is the slowest running speed, was significantly greater in women than in men (p<.05), and the vertical impulse at 16 km/h, which is the fastest running speed, was significantly greater in men than in women (p<.05). The absolute anteroposterior impulse at 8 km/h was significantly greater in women than in men (p<.05). In addition, as the running speed increased, impact peak, active peak, impact loading rate, breaking peak, propulsive peak, and anteroposterior impulse were significantly increased, but vertical impulse was significantly decreased (p<.05). Conclusion: The impact loading rate is greater in women than in men regardless of different running speeds. Therefore, female runners might be exposed to the risk of potential injuries related to the bone and ligament. Moreover, increased running speeds could lead to higher possibility of running injuries.

• Biomolecules & Therapeutics
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• 제25권2호
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• pp.112-121
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• 2017

Drug-induced liver injury (DILI) is the serious and fatal drug-associated adverse effect, but its incidence is very low and individual variation in severity is substantial. Acetaminophen (APAP)-induced liver injury accounts for >50% of reported DILI cases but little is known for the cause of individual variations in the severity. Intrinsic genetic variation is considered a key element but the identity of the genes was not well-established. Here, pre-biopsy method and microarray technique was applied to uncover the key genes for APAP-induced liver injury in mice, and a cause and effect experiment employing quantitative real-time PCR was conducted to confirm the correlation between the uncovered genes and APAP-induced hepatotoxicity. We identified the innately and differentially expressed genes of mice susceptible to APAP-induced hepatotoxicity in the pre-biopsied liver tissue before APAP treatment through microarray analysis of the global gene expression profiles (Affymetrix $GeneChip^{(R)}$ Mouse Gene 1.0 ST for 28,853 genes). Expression of 16 genes including Gdap10, Lpl, Gabra3 and Ccrn4l were significantly different (t-test: FDR <10%) more than 1.5 fold in the susceptible animals than resistant. To confirm the association with the susceptibility to APAP-induced hepatotoxicity, another set of animals were measured for the expression level of selected 4 genes (higher two and lower two genes) in the liver pre-biopsy and their sensitivity to APAP-induced hepatotoxicity was evaluated by post hoc. Notably, the expressions of Gabra3 and Lpl were significantly correlated with the severity of liver injury (p<0.05) demonstrating that these genes may be linked to the susceptibility to APAP-induced hepatotoxicity.

• 한국산학기술학회논문지
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• 제20권10호
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• pp.125-132
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• 2019

수중폭발로 인해 발생된 충격파에 노출된 유체(대부분 해수)는 유체장 내 압력과 속력 등의 물리적 변화에 따른 장력을 견딜 수 없으므로 캐비테이션(기포 또는 기공)이 발생하게 되고 이때 발생된 캐비테이션은 수중폭발의 연쇄 과정 중 구조물에 미치는 충격하중의 전달 환경을 변화시킨다. 폭발물과 구조물 간의 거리가 비교적 가까워 선체구조의 국부적 손상에 관심을 가지는 근거리 수중폭발연구에서 관심을 가지는 물리적 현상은 크게 3가지로 초기충격파 그리고 그것과 선체구조와의 상호작용, 국부 캐비테이션, 국부 캐비테이션 폐쇄 후 2차 충격파이다. 본 논문의 관심은 근거리 수중폭발에 따른 국소 캐비테이션이므로 수면과 해저로부터의 반사파는 고려하지 않는다. 유체와 구조에 관한 각각의 지배 방정식을 유도하고 이를 간단한 1차원 무한평판 문제에 적용, 수치적으로 해석하여 엄밀해와 비교해봄으로써 제안된 비연성 해석방법을 검증한다. 비연성 해석방법은 유체-구조 결합 해석방법보다 계산상 효율이 높으며 간단함에도 불구하고 상대적으로 높은 수준의 정확도를 얻을 수 있다는 점에서 유용하다. 본 논문을 통해 수중폭발과 같은 복잡한 물리적 상황에서의 유체-구조 상호작용 현상에 대한 이해와 실질적인 문제에 개념적 이해를 높이는 데 도움이 될 것이다.

• 한국컴퓨터정보학회논문지
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• 제20권1호
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• pp.75-83
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• 2015

플레이어의 흥미를 유발하기 위해서 보다 현실감 있는 캐릭터의 중요성이 증대됨에 따라, 캐릭터 디자인 단계에서 성격을 적용하여 사람처럼 행동하는 캐릭터가 필요한 시점이다. 그러나 기존 게임 캐릭터는 개발 단계에서 성격이 정해진 것이 아니므로 사람과 비슷한 행동을 하고 표현을 하는 캐릭터를 창출하는 데는 한계가 있다. 따라서 본 논문에서는 게임 캐릭터에 적용하기 위한 목적으로 5대 성격요인과 자아 상태의 연관성을 증명한다. 5대 성격요인과 자아 상태는 모두 사람의 성격적인 특성과 관련된 이론이다. 5대 성격요인은 사람의 내부적인 특성을, 자아 상태는 외부적으로 관찰 가능한 사람의 특성을 중점으로 하고 있다. 이점에서 두 이론은 어떠한 특성을 정의하고 이에 따라 행동하도록 설계된 캐릭터에 적용하기 적합하다. 즉, 5대 성격요인의 성격에 따라 설정되고, 자아 상태를 이용하여 이 성격에 따른 행동을 표현하는 캐릭터를 개발할 수 있다. 이 작업을 위해서는 우선 두 이론에 관련이 있음을 밝혀낼 필요가 있다. 이를 위해 본 논문에서는 기존 성격연구에 활용된 방법론인 형용사 체크리스트를 이용해 두 이론의 연관성을 밝혀내고 이 결과를 설문을 이용하여 분석한다. 향후 이 두 이론의 연관성에 따른 성격 모델을 구축하여, 캐릭터가 성격에 따라 행동하는 즉, 사실적 행위에 기반을 둔 캐릭터를 개발할 수 있을 것이라 기대한다.

• 한국운동역학회지
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• 제31권4호
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• pp.308-313
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• 2021

Objective: The purpose of this study was to investigate the effect of different kettlebell mass (30%, 40%, and 50% of the body mass) on kinematics and kinetic variables of kettlebell swing. Method: Total of 16 healthy male who had at least 1 year of kettlebell training experience were participated in this study (age: 31.69 ± 3.46 yrd., height: 173.38 ± 4.84 cm, body mass: 74.53 ± 6.45 kg). In this study, a 13-segments whole-body model (upper trunk, lower trunk, pelvis, both side of forearm, upperarm, thigh, and shank) was used and 26 reflective markers were attached to the body to identify the segments during the movement. A 3-dimensional motion analysis with 8 infrared cameras and 4 channeled EMG was performed to find the effect of kettlebell mass on its swing. To verify the kettlebell mass effect, a one-way ANOVA with a repeated measure was used and the statistical significance level was set at 𝛼=.05. Results: Firstly, in all lower extremity joints and thoracic vertebrae, a statistically significant change in angle was shown according to an increase in kettlebell mass during kettlebell swing (p<.05). Secondly, in both the up-swing and down-swing phases, the knee joint and ankle joint ROM showed a statistically significant increase as the kettlebell mass increased (p<.05) but no statistically significant difference was found in the hip joint and thoracic spine (p>.05). Lastly, the hamstrings muscle activity was statistically significantly increased as the kettlebell mass increased during up-swing phases (p<.05). Also, as the kettlebell mass increased in P4 of the down swing phase, the gluteus maximus showed a statistically significantly increased muscle activation, whereas the rectus femoris showed a statistically significantly decreased muscle activation (p <.05). Conclusion: As a result of this study, hip extension decreased and knee extension increased at 40% and 50% of body mass, and the spine also failed to maintain neutrality and increased flexion. Also, when kettlebell swings are performed with 50% of body mass, synergistic muscle dominance appears over 30% and 40% of body mass, which is judged to have a risk of potential injury. Therefore, it is thought that for beginners who start kettlebell exercise, swing practice should be performed with 30% of body mass. In addition, even in the case of experienced seniors, as the weight increases, the potential injury risk may increase, so it is thought that caution should be exercised when performing swings with 40% and 50% of body mass. In conclusion, it is thought that increasing the weight after sufficiently training with 30% of the weight of all subjects performing kettlebell swing is a way to maximize the exercise effect as well as prevent injury.

• 한국식품과학회지
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• 제53권6호
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• pp.739-748
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• 2021

본 연구에서는 가공용 쌀 이용성 향상을 위한 쌀 가공 제품개발과 쌀 생면 제조 기술 확보를 위해 반응표면분석법을 이용하여 글루텐 프리 쌀 우동의 주원료인 쌀가루, 변성전분(아세틸아디핀산이전분), 트레할로스의 함량에 따른 글루텐 프리 쌀 우동의 품질에 미치는 영향을 분석하고 제조 배합비를 Box-Behnken법을 이용하여 최적화하였다. 반응모형에서 쌀가루 함량이 높을수록 수분흡수율, 부피, 황색도, 탄성, 검성, 씹힘성, 응집성이 증가하였으며 변성전분의 함량이 적을수록 황색도, 탄성이 높았다. 수분함량, 명도, 황색도는 linear 모델로 결정되었으며 p-value는 <0.0001, 0.0113, 0.0214로 유의적 차이를 보였다. 글루텐 프리 쌀 우동 주원료의 배합비는 트레할로스의 첨가 없이 쌀가루 60 g, 변성전분 18.81 g 사용하는 것이 바람직한 것으로 나타났다. 반응표면 분석법을 통한 최적 배합비에 따라 글루텐 프리 쌀 우동을 제조한 결과 백색도는 73.09, 수분 흡수율은 59.73%, 부피 32.61 mL, 탁도 0.44, 조리손실율 5.74%, 용출고형분 함량은 1.86%였다. 이 연구 결과는 글루텐 프리 쌀 우동 제조에 기초자료로 제공되어 향후 제품 개발에 도움이 될 것으로 여겨진다.

• 한국환경생태학회지
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• 제33권1호
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• pp.64-74
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• 2019

본 연구의 목적은 무등산국립공원 식생복원사업후 경과년수에 따라 식생변화상태, 인위적 복원조치에 대한 효과 등 식생회복정도를 평가하는데 있다. 1996년에 시행한 중봉 군부대 이전 복원공사지역과 1999년에 누에봉 방송통신시설 철거 복원공사지역에 식물상, 상대우점치, 종다양도, 유사도 등을 분석하기 위해 모니터링 시험구 11개소, 복원공사지역 인근 자연림에 대조구 10개소 등 총 21개소의 조사구를 설치하여 복원공사지역과 주변 자연림간 식생회복 정도를 평가하였다. 복원 후 17년이 경과한 중봉 군부대 이전 복원공사지역은 종구성의 유사도지수 평균치가 3.5%로 낮았으나 관목층의 수고는 112%의 수준으로 회복되었다. 복원 후 14년이 경과한 누에봉 방송통신시설 철거 복원공사지역의 유사도지수 평균치는 5.05%이었고 산철쭉과 털진달래가 출현하는 관목층의 수고는 82.6% 수준으로 회복되었다. 무등산국립공원과 다른 국립공원지역의 아고산대 복원평가방법과 복원공사기술개발을 위하여 복원공사지역의 지속적인 모니터링이 필요하다.

• 대한통합의학회지
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• 제6권4호
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• pp.39-45
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• 2018

Purpose : The purpose of this study is to investigate the effect of core motion pattern on abdominal muscle thickness on unstable support surface using sling suspension system and to provide an effective exercise program for therapeutic rehabilitation in clinical practice. Methods : In this study, we used the flank exercise using a sling. It was intended for 21 healthy men and 9 healthy women. Before and after the exercise of the subjects, abdominal muscles (EO, IO, TrA the thickness of the muscle) was determined using a diagnostic ultrasonic apparatus. The period of exercise was 3 times a week for 6 weeks. The exercise for each group started with 3 sets per week and 1 set per week was added. A description of the method and attitude of each exercise is as follows. First, the push-up flank 's exercise position is to put both feet on the sling and hold the floor with both hands. Second, the side flank's exercise postures take the side flanks, while the two legs hang on the sling and one arm supports the body with an articulated bend (about $90^{\circ}$). Third, the elbow flank's exercise position is to put the two legs on the sling, and take a flank posture with the arms bent and joint bending (about $90^{\circ}$). Results : There was a significant difference in the thickness of the muscle in the three flank movements after the exercise (p<.05). The most significant difference was in the change of the muscle thickness in the abdominal muscle, the outer muscle, and the stomach in the elbow flank exercise after exercise. There was a significant difference between the mean thickness of the abdominal muscles according to the flank type after exercise (p<.05). Conclusion : In flank exercise for core stabilization using sling, it is considered effective to strengthen the abdominal muscles by considering the support surface, difficulty level, change of movement pattern.

• 한국운동역학회지
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• 제31권2호
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• pp.133-139
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• 2021

Objective: This study aims to verify the conventional deadlift motions using by two different grips, thereby elucidating the grounds for effective training methods that can minimize the risk of injury. Method: Total of 18 healthy young adults were recruited for this study (age: 25.11±2.19 yrs., height: 175.67±5.22 cm, body mass: 78.5±8.09 kg, 1-RM: 125.75±19.48 kg). All participants were asked to perform conventional deadlift with two types of grips which are overhand grip (OG) and underhand grip (UG). In each grip, participant perform the deadlift with 50% and 80% of the pre-measured 1-RM. A 3-dimensional motion analysis with 8 infrared cameras and 3 channels of EMG was performed in this study. A two-way ANOVA (group × load) with repeated measure was used for statistical verification. The significant level was set at α=.05. Results: There were significant differences in grip type and weight on the right shoulder joint, and only significant difference in grip on the left shoulder joint (p<.05). The hip joint ROM was significantly increased as the weight increased in both types of grips on phase 1, while the ROM of hip joint was significantly decreased as the weight increased only in the case of OG on phase 2 (p<.05). In case of the OG, as the weight, increased significantly increased L1 ROM and L3 ROM were revealed on phase 1 and phase 2, respectively (p<.05). Moreover, as the weight increased, UG revealed significantly decreased L5 ROM on phase 1, while both grips showed significantly increased ROM on phase 2 (p<.05). In addition, the erector spinae and the biceps femoris, which are synergist for the motion, showed a significant difference in both types of grip according to the weight (p<.05). The muscle activity ratio of gluteus maximus/biceps femoris showed a significant difference only in the UG according to the weight (p<.05). Conclusion: In conclusion, beginners might be suggested to use the UG for maintaining the neutral state of the lumbar spine and focus on the gluteus maximus muscle, which is the main activation muscle. For the experts, it may recommend alternative use of the OG and UG according to the training purpose to minimize the compensation effect.

• 디지털융복합연구
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• 제19권8호
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• pp.89-100
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• 2021

국가 사이버 역량평가는 국가 차원의 사이버역량 강화를 위해 필요한 요소와 그에 대한 국가별 수준에 대한 정보를 제공하기 때문에 국가 사이버안보 정책 개선을 위한 기초자료로 활용할 수 있다. 그러나 그간 우리나라를 평가대상국으로 포함하여 평가를 진행한 다양한 평가결과로부터 국내 사이버역량 개선을 위한 정책적 분석은 다소 부족하였다. 이에 본 논문에서는 미국 하버드 대학의 벨퍼센터에서 수행한 국가 사이버 추진력 지수(NCPI)의 평가결과에 대해 IPA(Importance-Performance Analysis) 기법을 변형·적용해봄으로써 우리나라 사이버안보 정책 개선 방안을 도출하고자 하였다. 분석 결과, 우리나라는 공격과 감시 목적의 사이버 기능 활용에 관한 정책 의제 형성이 필요하고, 인텔리전스와 방어에 관한 정책의 실효성을 향상하기 위한 노력이 필요하다는 결론을 얻을 수 있었다. 또한, 관련 정책 의제를 다루는 국내외 연구사례를 살펴봄으로써 정책개선 방향을 제시하며, 각 정책개선 방향에 관한 심층 연구를 추진할 것을 향후 과제로 제안하였다. 나아가 국가 사이버 역량평가 모델의 정책 분석적 활용을 향상하기 위해서는 국내 실정을 반영하는 자체 모델 개발·활용이 필요하며, 이때 본 연구에서 제안한 평가결과 분석 방안을 활용할 수 있을 것으로 기대한다.