Expression Levels of GABA-A Receptor Subunit Alpha 3, Gabra3 and Lipoprotein Lipase, Lpl Are Associated with the Susceptibility to Acetaminophen-Induced Hepatotoxicity |
Kim, Minjeong
(College of Pharmacy, Ewha Womans University)
Yun, Jun-Won (Department of Experimental Animal Research, Biomedical Research Institute, Seoul National University Hospital) Shin, Kyeho (Department of Beauty Coordination, Suwon Science College) Cho, Yejin (Severance Biomedical Science Institute, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine) Yang, Mijeong (Severance Biomedical Science Institute, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine) Nam, Ki Taek (Severance Biomedical Science Institute, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine) Lim, Kyung-Min (College of Pharmacy, Ewha Womans University) |
1 | Liu, H., Nakagawa, T., Kanematsu, T., Uchida, T. and Tsuji, S. (1999) Isolation of 10 differentially expressed cDNAs in differentiated Neuro2a cells induced through controlled expression of the GD3 synthase gene. J. Neurochem. 72, 1781-1790. |
2 | Liu, H. H., Lu, P., Guo, Y. Y., Farrell, E., Zhang, X., Zheng, M., Bosano, B., Zhang, Z., Allard, J., Liao, G., Fu, S., Chen, J., Dolim, K., Kuroda, A., Usuka, J., Cheng, J., Tao, W., Welch, K., Liu, Y., Pease, J., de Keczer, S. A., Masjedizadeh, M., Hu, J. S., Weller, P., Garrow, T. and Peltz, G. (2010) An integrative genomic analysis identifies Bhmt2 as a diet-dependent genetic factor protecting against acetaminophen-induced liver toxicity. Genome Res. 20, 28-35. DOI |
3 | Lu, X. Y., Hu, B., Zheng, J., Ji, C., Fan, X. H. and Gao, Y. (2015) Predose and postdose blood gene expression profiles identify the individuals susceptible to acetaminophen-induced liver injury in rats. PLoS ONE 10, e0141750. DOI |
4 | Michalopoulos, G. K. (2007) Liver regeneration. J. Cell. Physiol. 213, 286-300. DOI |
5 | Moe, M., Lien, S., Bendixen, C., Hedegaard, J., Hornshoj, H., Berget, I., Meuwissen, T. H. and Grindflek, E. (2008) Gene expression profiles in liver of pigs with extreme high and low levels of androstenone. BMC Vet. Res. 4, 29. DOI |
6 | Oh, J.-H., Yoon, H.-J., Lim, J.-S., Park, H.-J., Cho, J.-W., Kwon, M.-S. and Yoon, S.-J. (2009) Analysis of Gene Expression in 4, 4'-Methylenedianiline-induced Acute Hepatotoxicity. Toxicol. Res. 25, 85-92. DOI |
7 | Ostapowicz, G., Fontana, R. J., Schiodt, F. V., Larson, A., Davern, T. J., Han, S. H., McCashland, T. M., Shakil, A. O., Hay, J. E., Hynan, L., Crippin, J. S., Blei, A. T., Samuel, G., Reisch, J. and Lee, W. M. (2002) Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States. Ann. Intern. Med. 137, 947-954. DOI |
8 | Baron, A. D., Brechtel, G., Wallace, P. and Edelman, S. V. (1988) Rates and tissue sites of non-insulin- and insulin-mediated glucose uptake in humans. Am. J. Physiol. 255, E769-E774. |
9 | Bessems, J. G. and Vermeulen, N. P. (2001) Paracetamol (acetaminophen)-induced toxicity: molecular and biochemical mechanisms, analogues and protective approaches. Crit. Rev. Toxicol. 31, 55-138. DOI |
10 | Biju, M. P., Pyroja, S., Rajeshkumar, N. V. and Paulose, C. S. (2001) Hepatic GABA(A) receptor functional regulation during rat liver cell proliferation. Hepatol. Res. 21, 136-146. DOI |
11 | Yun, J. W., Kim, C. W., Bae, I. H., Park, Y. H., Chung, J. H., Lim, K. M. and Kang, K. S. (2010) Expression levels of pituitary tumor transforming 1 and glutathione-S-transferase theta 3 are associated with the individual susceptibility to D-galactosamine-induced hepatotoxicity. Toxicol. Appl. Pharmacol. 242, 91-99. DOI |
12 | Watkins, P. B., Kaplowitz, N., Slattery, J. T., Colonese, C. R., Colucci, S. V., Stewart, P. W. and Harris, S. C. (2006) Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial. JAMA 296, 87-93. DOI |
13 | Watson, W. A., Litovitz, T. L., Klein-Schwartz, W., Rodgers, G. C., Youniss, J., Reid, N., Rouse, W. G., Rembert, R. S. and Borys, D. (2004) 2003 Annual Report of the American Association of Poison Control Centers Toxic Exposure Surveillance System. Am. J. Emerg. Med. 22, 335-404. DOI |
14 | Yun, J. W., Kim, C. W., Bae, I. H., Park, Y. H., Chung, J. H., Lim, K. M. and Kang, K. S. (2009) Determination of the key innate genes related to individual variation in carbon tetrachloride-induced hepatotoxicity using a pre-biopsy procedure. Toxicol. Appl. Pharmacol. 239, 55-63. DOI |
15 | Reuben, A., Koch, D. G. and Lee, W. M. (2010) Drug-induced acute liver failure: results of a U.S. multicenter, prospective study. Hepatology 52, 2065-2076. DOI |
16 | Bozogluer, E., Madenoglu, H., Aksu, R., Bicer, C., Yazici, C. and Boyaci, A. (2012) The effect of different doses of flumazenil on acetaminophen toxicity in rats. Bratisl. Lek. Listy 113, 525-528. |
17 | Chang, C. Y. and Schiano, T. D. (2007) Review article: drug hepatotoxicity. Aliment. Pharmacol. Ther. 25, 1135-1151. DOI |
18 | Clark, S. J., Shojaee-Moradie, F., Croos, P., Seed, P. T., Umpleby, A. M., Wendon, J. A. and Miell, J. (2001) Temporal changes in insulin sensitivity following the development of acute liver failure secondary to acetaminophen. Hepatology 34, 109-115. DOI |
19 | Park, A. The FDA's painkiller warning: how to avoid taking too much [Internet]. TIME; 2006 Dec 20. Available from: http://content.time.com/time/health/article/0,8599,1572012,00.html. |
20 | Prescott, L. F., Park, J., Ballantyne, A., Adriaenssens, P. and Proudfoot, A. T. (1977) Treatment of paracetamol (acetaminophen) poisoning with N-acetylcysteine. Lancet 2, 432-434. |
21 | Saha, B. and Nandi, D. (2009) Farnesyltransferase inhibitors reduce ras activation and ameliorate acetaminophen-induced liver injury in mice. Hepatology 50, 1547-1557. DOI |
22 | Sanaka, M., Kuyama, Y. and Yamanaka, M. (1998) Guide for judicious use of the paracetamol absorption technique in a study of gastric emptying rate of liquids. J. Gastroenterol. 33, 785-791. DOI |
23 | Shin, J. H., Lee, C. W., Oh, S. J., Yun, J., Kang, M. R., Han, S. B., Park, H., Jung, J. C., Chung, Y. H. and Kang, J. S. (2014) Hepatoprotective Effect of Aged Black Garlic Extract in Rodents. Toxicol. Res. 30, 49-54. DOI |
24 | Stamper, B. D., Bammler, T. K., Beyer, R. P., Farin, F. M. and Nelson, S. D. (2010) Differential regulation of mitogen-activated protein kinase pathways by acetaminophen and its nonhepatotoxic regioisomer 3'-hydroxyacetanilide in TAMH cells. Toxicol. Sci. 116, 164-173. DOI |
25 | Stephens, C., Lucena, M. I. and Andrade, R. J. (2012) Genetic variations in drug-induced liver injury (DILI): resolving the puzzle. Front. Genet. 3, 253. |
26 | Umbright, C., Sellamuthu, R., Li, S. Q., Kashon, M., Luster, M. and Joseph, P. (2010) Blood gene expression markers to detect and distinguish target organ toxicity. Mol. Cell. Biochem. 335, 223-234. DOI |
27 | Fausto, N., Campbell, J. S. and Riehle, K. J. (2006) Liver regeneration. Hepatology 43, S45-S53. DOI |
28 | Yun, J. W., Kim, M., Cho, S. D., Lee, J. Y., Bae, O. N. and Lim, K. M. (2014) Highly expressed protein kinase A inhibitor alpha and suppression of protein kinase A may potentiate acetaminophen-induced hepatotoxicity. Toxicol. Lett. 229, 59-65. DOI |
29 | Wang, H. and Eckel, R. H. (2009) Lipoprotein lipase: from gene to obesity. Am. J. Physiol. Endocrinol. Metab. 297, E271-E288. DOI |
30 | Draghici, S., Khatri, P., Eklund, A. C. and Szallasi, Z. (2006) Reliability and reproducibility issues in DNA microarray measurements. Trends Genet. 22, 101-109. DOI |
31 | Goldberg, I. J. (1996) Lipoprotein lipase and lipolysis: central roles in lipoprotein metabolism and atherogenesis. J. Lipid Res. 37, 693-707. |
32 | Green, C. B., Douris, N., Kojima, S., Strayer, C. A., Fogerty, J., Lourim, D., Keller, S. R. and Besharse, J. C. (2007) Loss of Nocturnin, a circadian deadenylase, confers resistance to hepatic steatosis and diet-induced obesity. Proc. Natl. Acad. Sci. U.S.A. 104, 9888-9893. DOI |
33 | Gutschner, T., Hammerle, M., Eissmann, M., Hsu, J., Kim, Y., Hung, G., Revenko, A., Arun, G., Stentrup, M., Gross, M., Zornig, M., MacLeod, A. R., Spector, D. L. and Diederichs, S. (2013) The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells. Cancer Res. 73, 1180-1189. DOI |
34 | Hinson, J. A., Roberts, D. W. and James, L. P. (2010) Mechanisms of acetaminophen-induced liver necrosis. Handb. Exp. Pharmacol. 196, 369-405. |
35 | Lazarou, J., Pomeranz, B. H. and Corey, P. N. (1998) Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA 279, 1200-1205. DOI |
36 | Ji, P., Diederichs, S., Wang, W. B., Boing, S., Metzger, R., Schneider, P. M., Tidow, N., Brandt, B., Buerger, H., Bulk, E., Thomas, M., Berdel, W. E., Serve, H. and Muller-Tidow, C. (2003) MALAT-1, a novel noncoding RNA, and thymosin beta 4 predict metastasis and survival in early-stage non-small cell lung cancer. Oncogene 22, 8031-8041. DOI |
37 | Johnsen, S. A., Subramaniam, M., Janknecht, R. and Spelsberg, T. C. (2002) TGF beta inducible early gene enhances TGF beta/Smaddependent transcriptional responses. Oncogene 21, 5783-5790. DOI |
38 | Kim, J. K., Fillmore, J. J., Chen, Y., Yu, C., Moore, I. K., Pypaert, M., Lutz, E. P., Kako, Y., Velez-Carrasco, W., Goldberg, I. J., Breslow, J. L. and Shulman, G. I. (2001) Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance. Proc. Natl. Acad. Sci. U.S.A. 98, 7522-7527. DOI |
39 | Krenzelok, E. P. (2009) The FDA Acetaminophen Advisory Committee Meeting - what is the future of acetaminophen in the United States? The perspective of a committee member. Clin. Toxicol. (Phila.) 47, 784-789. DOI |
40 | Larson, A. M., Polson, J., Fontana, R. J., Davern, T. J., Lalani, E., Hynan, L. S., Reisch, J. S., Schiodt, F. V., Ostapowicz, G., Shakil, A. O. and Lee, W. M. (2005) Acetaminophen-induced acute liver failure: results of a United States multicenter, prospective study. Hepatology 42, 1364-1372. DOI |
41 | Lee, S. S., Buters, J. T., Pineau, T., Fernandez-Salguero, P. and Gonzalez, F. J. (1996) Role of CYP2E1 in the hepatotoxicity of acetaminophen. J. Biol. Chem. 271, 12063-12067. DOI |
42 | Lewis, J. H. (2000) Drug-induced liver disease. Med. Clin. North Am. 84, 1275-1311. DOI |