• Asian-Australasian Journal of Animal Sciences
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• v.31 no.3
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• pp.327-334
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• 2018

Objective: The objective of the present study was to validate genes and genomic regions associated with carcass weight using a low-density single nucleotide polymorphism (SNP) Chip in Hanwoo cattle breed. Methods: Commercial Hanwoo steers (n = 220) were genotyped with 20K GeneSeek genomic profiler BeadChip. After applying the quality control of criteria of a call rate ${\geq}90%$ and minor allele frequency (MAF) ${\geq}0.01$, a total of 15,235 autosomal SNPs were left for genome-wide association (GWA) analysis. The GWA tests were performed using single-locus mixed linear model. Age at slaughter was fitted as fixed effect and sire included as a covariate. The level of genome-wide significance was set at $3.28{\times}10^{-6}$ (0.05/15,235), corresponding to Bonferroni correction for 15,235 multiple independent tests. Results: By employing EMMAX approach which is based on a mixed linear model and accounts for population stratification and relatedness, we identified 17 and 16 loci significantly (p<0.001) associated with carcass weight for the additive and dominant models, respectively. The second most significant (p = 0.000049) SNP (ARS-BFGL-NGS-28234) on bovine chromosome 4 (BTA4) at 21 Mb had an allele substitution effect of 43.45 kg. Some of the identified regions on BTA2, 6, 14, 22, and 24 were previously reported to be associated with quantitative trait loci for carcass weight in several beef cattle breeds. Conclusion: This is the first genome-wide association study using SNP chips on commercial Hanwoo steers, and some of the loci newly identified in this study may help to better DNA markers that determine increased beef production in commercial Hanwoo cattle. Further studies using a larger sample size will allow confirmation of the candidates identified in this study.

• Journal of Korean Academy of Nursing
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• v.30 no.5
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• pp.1156-1169
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• 2000

The study was aimed at developing an independent hospice center model that would be best suited for Korea based on a literature review and the current status of local and international hospices. For the study, five local and six international hospice organizations were surveyed. Components of the hospice center model include philosophy, purpose, resources (workers, facilities, and equipment), allocation of resources, management, financial support and hospice team service. The following is a summary of the developed model: Philosophies for the hospice center were set as follows: based on the dignity of human life and humanism, help patients spend the rest of their days in a meaningful way and accept life positively. On the staff side, to pursue a team-oriented holistic approach to improve comfort and quality of life for terminally ill persons and their families. The hospice center should have 20 beds with single, two, and four bed rooms. The center should employ, either on a part-time or full-time basis, a center director, nurses, doctors, chaplains, social workers, pharmacists, dieticians, therapists, and volunteers. In addition, it will need an administrative staff, facility managers and nurses aides. The hospice should also be equipped with facilities for patients, their families, and team members, furnished with equipment and goods at the same level of a hospital. represented by a center director who reports to a board and an advisory committee. Also, the center director administers a steering committee and five departments, namely, Administration, Nursing Service, Social Welfare, Religious Services, and Medical Service. Furthermore, the center should be able to utilize a direct and support delivery systems. The direct delivery system allows the hospice center to receive requests from, or transfer patients to, hospitals, clinics, other hospice organizations (by type), public health centers, religious organizations, social welfare organizations, patients, and their guardians. On the other hand, the support delivery system provides a link to outside facilities of various medical suppliers. In terms of management, details were made with regards to personnel management, records, infection control, safety, supplies and quality management. For financial support, some form of medical insurance coverage for hospice services, ways to promote a donation system and fund raising were examined. Hospice team service to be provided by the hospice center was categorized into assessment, physical care, emotional care, spiritual care, bereavement service, medication, education and demonstrations, medical supplies rental, request service, volunteer service, and respite service. Based on the results, the study has drawn up the following suggestions: 1. The proposed model for a hospice center as presented in the study needs to be tested with a pilot project. 2. Studies on criteria for legal approval and license for a hospice center need to be conducted to develop policies. 3. Studies on developing a hospice charge system and hospice standards that meet local conditions in Korea need to be conducted.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.13 no.6
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• pp.64-76
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• 2014

This study identified the causes of errors that could take place in the estimation process of vehicle miles traveled and quantified the effects of each of those causes on the estimation accuracy of vehicle miles traveled via error rate to propose an efficient way to estimate vehicle miles traveled. The study proceeded as follows: first, the study established survey data of vehicle miles traveled in the pilot test areas to test the accuracy of a method to estimate vehicle miles traveled. Second, the causes of errors with the estimation of vehicle miles traveled were categorized into errors with the sample size, sampling methods, and homogeneous link setting methods. In addition, many different methodologies were set to minimize errors with the estimation of vehicle miles traveled according to each of the causes. Third, error rates of estimation of vehicle miles traveled were compared and analyzed according to each of the methodologies. Finally, a toy network was established to propose a way of estimating vehicle miles traveled by taking the local characteristics into consideration. The study finds its significance in that it proposed an efficient way to estimate vehicle miles traveled through an experiment and planning approach and made use of survey data of vehicle miles traveled to test estimation accuracy. The proposed way of estimating vehicle miles traveled by taking into account the local characteristics will make a contribution to the estimation of vehicle miles traveled by the areas in future along with the level of data offered in the study.

• Journal of Korean Society of Environmental Engineers
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• v.31 no.9
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• pp.825-830
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• 2009

Pharmaceutical compounds enter the water environment through the diverse pathways. Because their concentration in the water environment was frequently detected in the level of ppt to ppb, the monitoring system should be optimized as much as possible for finding appropriate management policies and technical solutions. One Factor At a Time (OFAT) approach approximating the response with a single variable has been preferred for the optimization of LC-MS/MS operational conditions. However, it is common that variables in analytical instruments are interdependent. Therefore, the best condition could be found by using the statistical optimization method changing multiple variables at a time. In this research, response surface analysis (RSA) was applied to the LC-MS/MS analysis of emerging antibiotic compound, sulfamethoxazole, for the best sensitivity. In the screening test, fragmentation energy and collision voltage were selected as independent variables. They were changed simultaneously for the statistical optimization and a polynomial equation was fit to the data set. The correlation coefficient, $R^2$ valuerepresented 0.9947 and the error between the predicted and observed value showed only 3.41% at the random condition, fragmentation energy of 60 and collision voltage of 17 eV. Therefore, it was concluded that the model derived by RSA successfully predict the response. The optimal conditions identified by the model were fragmentation energy of 116.6 and collision voltage of 10.9 eV. This RSA can be extensively utilized for optimizing conditions of solid-phase extraction and liquid chromatography.

• The Journal of Korean Academy of Prosthodontics
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• v.36 no.3
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• pp.468-482
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• 1998

Since the concept of osseointegration was introduced by Branemark of Sweden, dental implants have been used for various dental prosthetic treatments. The survival rate of dental implant is likely to be closely related to the total biomechanical role of each component of implant system. The use of interchangeable component is very attractive for dental practitioners because such an approach would save treatment cost, flexibility of prosthetic treatment options as well as conveniences. Therefore, the use of interchangeable implant system has been increasing without scientific assessment of safety and efficacy of various interchangeable implant system. The purpose of this study, therefore, were to compare the geometric characteristic of four interchangeable dental implant screws and the loosening torque of these screws. Four types of dental implant screws tested in this study were Nobelpharma, 3i, Impla-med, Restore. Four screws each of the test specimens were subjected for scanning electron microscopic examinations under the same condition and a 35x magnified standard SEM picture was objected from each test specimen using JSM-5200 scanning microscope. From each of the SEM pictures, eight parameters. i.e., diameter of screw head. screw length, thread pitch, major diameter. neck diameter, neck length, crest width and root width were determined using a caliper. The measurement for each parameters were then corrected for their magnification factor. The loosening torque were also determined by using a torque gauge. All of the measurements were statistically analyzed by ANOVA test and multiple range test. Statistical significance was set in advance at the probability level of less than 0.05. All analyses were done with SPSS software for the personal computer. The conclusion obtained from this studies were summarized as the following; 1. No statistically significances were noted in the thread pitch. and crest width in the four screws, and in the case of major diameter, the Impla-med screw was significantly smaller than the other three screws (p<0.05). Therefore, four implant bolts could be physically inserted in a abutment nuts. 2. The diameter of screw head was decreased in the order of Restore, 3i, Nobelpharma, Impla-med screws and the length of screws were decreased in the order of 3i, Restore, Nobelpharma and Impla-med. The diameter of neck was decreased in the order of Impla-med, Restore. Nobelpharma, 3i screws. The differences of each of these parameters were statistically significant (p<0.05). The width of root of screws were decreased in the order of Nobelpharma, Impla-med, Restore and 3i. The differences among Nobelpharma and Impla-med. Restore and 3i were statistically significant (p<0.05). 3. When the screws were loosening 1, 3, 4 and 5 times, the loosening torque for Impla-med and 3i screws were significantly higher than that of Nobelpharma or Restore screws (p<0.05). However, when statistically smaller than that of 3i, Restore or Nobelpharma screws(p<0.05).

• Journal of Internet Computing and Services
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• v.12 no.4
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• pp.157-172
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• 2011

The latest active studies on distributed OLAP to adopt a distributed environment are mainly focused on DHT P2P OLAP and Grid OLAP. However, these approaches have its weak points, the P2P OLAP has limitations to multidimensional range queries in the cloud computing environment due to the nature of structured P2P. On the other hand, the Grid OLAP has no regard for adjacency and time series. It focused on its own sub set lookup algorithm. To overcome the above limits, this paper proposes an efficient central managed P2P approach for a cloud computing environment. When a multi-level hybrid P2P method is combined with an index load distribution scheme, the performance of a multi-dimensional range query is enhanced. The proposed scheme makes the OLAP query results of a user to be able to reused by other users' volatile cube search. For this purpose, this paper examines the combination of an aggregation cube hierarchy tree, a quad-tree, and an interval-tree as an efficient index structure. As a result, the proposed cloud P2P OLAP scheme can manage the adjacency and time series factor of an OLAP query. The performance of the proposed scheme is analyzed by a series of experiments to identify its various characteristics.

• Journal of KIISE:Databases
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• v.34 no.1
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• pp.1-17
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• 2007

As XML is becoming a de facto standard for distribution and sharing of information, the need for an efficient yet secure access of XML data has become very important. To enforce the fine-level granularity requirement, authorization models for regulating access to XML documents use XPath which is a standard for specifying parts of XML data and a suitable language for both query processing. An access control environment for XML documents and some techniques to deal with authorization priorities and conflict resolution issues are proposed. Despite this, relatively little work has been done to enforce access controls particularly for XML databases in the case of query access. Developing an efficient mechanism for XML databases to control query-based access is therefore the central theme of this paper. This work is a proposal for an efficient yet secure XML access control system. The basic idea utilized is that a user query interaction with only necessary access control rules is modified to an alternative form which is guaranteed to have no access violations using tree-aware metadata of XML schemes and set operators supported by XPath 2.0. The scheme can be applied to any XML database management system and has several advantages over other suggested schemes. These include implementation easiness, small execution time overhead, fine-grained controls, and safe and correct query modification. The experimental results clearly demonstrate the efficiency of the approach.

• The Journal of Information Systems
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• v.25 no.2
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• pp.1-25
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• 2016

Purpose The innovation capability nowadays has become increasingly prominent in the universities not only for schools but also for teachers. However, due to less attention to the knowledge utilization and management, also some objective constraints, which caused the low level of the innovation capacity for our universities teachers under the current development in China. Meanwhile, transactive memory system (TMS) and knowledge sharing are important contents in knowledge management. The combination of both systems will contribute to a much more comprehensive understanding and performance of knowledge management. The purpose of this study is to investigate the structural relationships between TMS, knowledge sharing, and innovation capability among Chinese university teachers' teams, and to propose the practical implication to integrate effectively internal knowledge of the team to improve innovation capability. Design/methodology/approach In order to exam and verify the hypothesis proposed, we developed a questionnaire with 16 survey items, and each item comes with a five-point Likert-type scale. Hyperlink of online questionnaire was shared through WeChat. It's collected 201 responses from 14 universities in China, and the responders are teaching groups' leaders. And all together 191 responses were filtered out as the valid samples. And we analyze the data set and test research hypotheses by using SPSS 22.0 and AMOS 22.0. Findings All hypotheses are supported. The results reveal that knowledge sharing plays an important role in this study as the mediating role. TMS is positively associated with the innovation capability. And the knowledge sharing plays a significant role as mediating value between them, and influences the TMS's effect on innovation capability. It's thus cleared that if our teachers could well communicate, exchange and collaborate with other teachers in the same group, the innovation capability among the teachers would be improved effectively.

• Ocean and Polar Research
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• v.41 no.4
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• pp.311-318
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• 2019

We analyzed the preliminary survey data (2014-2016) of macrobenthic community biomass (n = 112) from the wind farm area located in the southern part of the west coast of Korea and compared this data with data from the entire west coast (n = 369; 2006-2008). Modal classes from frequency distributions were 6 times higher in the latter (5 vs. 32 g/㎡). The mean and median values of the latter were 1.3 and 1.7 times higher (mean, 20.7 vs. 27.8 g/㎡; median, 17.1 vs. 29.5 g/㎡), and the maximum value was 3.4 times higher. Mood's median test showed significant difference at p-value = 0.01. We estimated the biomass-to-depth relationships from each data set by using Akaike Information Criterion and regarded the non-overlap of the 95% confidence intervals as indicating significant difference. The biomass was different from a 10 m depth below, and 3 times higher in the west coast at around 20 m compared with the maximum depth of the wind farm area. A local event of catastrophic sedimentation ranging from 1 to 2 m was observed in the wind farm during winter surveys. This could be a probable source of the lower biomass, but information on biomass seasonality and a natural experimental approach seem to be needed for the conduct of further studies. This study is meaningful in that it provided the background to assess future changes by understanding the lower level of benthic productivity in the area. We expect this study will contribute to the preparation of measures that can remove or mitigate the source of the lower biomass and improve the productivity of fishery resources in the area.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 1999.04a
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• pp.426-426
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• 1999

;There are many sources of uncertainty in a typical production and inventory system. There is uncertainty as to how many items customers will demand during the next day, week, month, or year. There is uncertainty about delivery times of the product. Uncertainty exacts a toll from management in a variety of ways. A spurt in a demand or a delay in production may lead to stockouts, with the potential for lost revenue and customer dissatisfaction. Firms typically hold inventory to provide protection against uncertainty. A cushion of inventory on hand allows management to face unexpected demands or delays in delivery with a reduced chance of incurring a stockout. The proposed strategies are used for the design of a probabilistic inventory system. In the traditional approach to the design of an inventory system, the goal is to find the best setting of various inventory control policy parameters such as the re-order level, review period, order quantity, etc. which would minimize the total inventory cost. The goals of the analysis need to be defined, so that robustness becomes an important design criterion. Moreover, one has to conceptualize and identify appropriate noise variables. There are two main goals for the inventory policy design. One is to minimize the average inventory cost and the stockouts. The other is to the variability for the average inventory cost and the stockouts The total average inventory cost is the sum of three components: the ordering cost, the holding cost, and the shortage costs. The shortage costs include the cost of the lost sales, cost of loss of goodwill, cost of customer dissatisfaction, etc. The noise factors for this design problem are identified to be: the mean demand rate and the mean lead time. Both the demand and the lead time are assumed to be normal random variables. Thus robustness for this inventory system is interpreted as insensitivity of the average inventory cost and the stockout to uncontrollable fluctuations in the mean demand rate and mean lead time. To make this inventory system for robustness, the concept of utility theory will be used. Utility theory is an analytical method for making a decision concerning an action to take, given a set of multiple criteria upon which the decision is to be based. Utility theory is appropriate for design having different scale such as demand rate and lead time since utility theory represents different scale across decision making attributes with zero to one ranks, higher preference modeled with a higher rank. Using utility theory, three design strategies, such as distance strategy, response strategy, and priority-based strategy. for the robust inventory system will be developed.loped.