• 생약학회지
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• 제31권4호
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• pp.430-433
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• 2000

Five compounds have been isolated from the stem of Caesalpinia japonica. On the basis of spectral evidences, the structures of these compounds were identified as 4',7-dihydroxyflavone, 3,4',7-trihydroxyflavone, cathechin, 3',4',7-trihydroxyflavone and 2',3,4',5,6,7-hexahydroxyflavone.

• Natural Product Sciences
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• 제6권3호
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• pp.139-141
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• 2000

From the $CHCl_3-fraction$ of the root cortex of Robinia pseudo-acacia, five compounds have been isolated. On the basis of spectral data, these compounds were identified as medicarpin, biochanin A, formononetin, 3'-methoxydaidzein.

• Bulletin of the Korean Chemical Society
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• 제27권3호
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• pp.426-428
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• 2006

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.258.3-258.3
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• 2003

The Seeds of Astragalus sinicus(Leguminosae) is used for the treatment of excretion of urine, circulation of blood and the throat inflammation in Korean traditional medicine. Eight flavonoids were isolated from 80％ Acetone extracts. The structure were elucidated as Quercetin 3-O-${\beta}$-D-Xylopyranosyl-(1\longrightarrow2)-${\beta}$-D-galactopyranoside, ampelopsin and myricetin by phytochemical and spectral evidences. The other compounds are understudied by 2D-NMR.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.197.3-197.3
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• 2003

From the EtOAc fraction of the MeOH extract of Albizzia julibrissin (Leguminosae), a rare 5-deoxy flavone (geraldone), a 3',4',7,8-tetrahydroxyflavanone, an isoflavone (daidzein), and five prenylated flavonoids (sophoflavescenol, kurarinone, kurarinol, kuraridin and kuraridinol) were isolated and identified based on the analysis of spectral data.(omitted)

• Archives of Pharmacal Research
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• 제25권3호
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• pp.320-324
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• 2002

The MeOH extract of Pueraria thunbergiana (Leguminosae) flowers and its fractions were subjected to Ames test to test the antimutagenicity. EtOAc fraction (1 mg/plate) decreased the number of revertants of Salmonella typhymurium TA100 by 95% against aflatoxin $B_1{\;}(AFB_1)$. Phytochemical isolation of the EtOAc fraction afforded four isoflavonoids (tectorigenin, glycitein, tectoridin and glycitin) and one saponin (kaikasaponin III). Though the three isoflavonoids other than tectoridin showed significant antimutagenicity, the activity of kaikasaponin III was the most potent. Kaikasaponin III (1 mg/plate) decreased the number of revertants of S. typhymurium TA 100 by 99% against $AFB_1$ but by 75% against N-methyl-N'-nitro-N-nitrosoguanidine (MNNG). Tectorigenin (1 mg/plate) inhibited the $AFB_1$-induced mutagenicity by 90% and MNNG-induced one by 76%. Glycitein and glycitin were less active than tectorigenin and kaikasaponin III. This result suggested that kaikasponin III prevents the metabolic activation of $AFB_1$ and scavenge electrophilic intermediate capable of mutation. The two components with potent activities, tectorigenin and kaikasaonin III, significantly prevented the malondialdehyde formation caused by bromobenzene in the rat.

• 한국산림과학회지
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• 제57권1호
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• pp.8-13
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• 1982

본(本) 조사(調査)는 1981년(年) 7월(月) 18일(日)에서 8월(月) 11일(日) 사이에 4개(個) 공단(工團)(포항(浦項), 울산(蔚山), 온산(温山) 및 여천(麗川))을 대상(對象)으로 오염발생원(汚染發生源)으로부터 2km이내(以內)의 식물(植物)의 종류(種類)와 내연성(耐煙性) 식물(植物)의 발굴(發掘) 및 대기오염(大氣汚染)이 식물생육(植物生育)에 미치고 있는 범위(範圍)를 지표식물(指標植物)에 의(依)한 육면적(肉眠的) 방법(方法)으로 조사(調査)하였으며 얻어진 결과(結果)는 다음과 같다. 1) 4개(個) 공단(工團)에 나타난 식물(植物)의 종류(種類)는 91과(科) 6아과(亞科) 213속(屬) 290종(種)이었고 과(科) 순위별(順位別)로 보면 포항공단내(浦項工團內)에는 54과(科) 102속(屬) 126종(種)으로 콩(科) 16종(種), 벼(科) 11종(種), 장미과(科) 9종(種) 및 국화과(科) 9종(種)의 순(順)이었고, 울산공단내(蔚山工團內)에는 61과(科) 131속(屬) 158종(種)으로 국화과(科) 17종(種), 벼과(科) 16종(種), 콩과(科) 15종(種), 장미과(科) 9종(種), 마디풀과(科) 7종(種) 및 가지과(科) 6종(種)의 순(順)이었고, 온산공단내(温山工團內)에는 46과(科) 98속(屬) 113종(種)으로 국화과(科) 12종(種), 벼과(科) 12종(種), 콩과(科) 12종(種), 장미과(科) 6종(種) 및 마디풀과(科) 6종(種)의 순(順)이었고, 여천공단내(麗川工團內)에는 71과(科) 150속(屬) 188종(種)으로 장미과(科) 15종(種), 콩과(科) 15종(種), 국화과(科) 15종(種), 벼과(科) 14종(種), 마디풀과(科) 7종(種) 및 버드나무과(科) 6종(種)의 순(順)이었다. 2) 4개(個) 공단지역(工團地域)에서 조사(調査)된 내연성(耐煙性) 식물(植物)은 표(表) 1과 같다. 3) 공단지역(工團地域)에 식재(植栽)될 추자수종(推蔗樹種)은 콩과(科)에 족제비싸리, 조록싸리, 싸리, 아까시나무 및 회화나무, 참나무과(科)에 상수리나무, 졸참나무 및 굴참나무, 버드나무과(科)에 은사시나무, 능수버들, 물푸레나무과(科)에 쥐똥나무, 광나무, 자작나무과(科)에 산오리나무, 노박덩굴과(科)에 사철나무, 인동과(科)에 아왜나무 및 소나무과(科)에 히말라야시이 다이다.

• 생약학회지
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• 제31권1호
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• pp.109-111
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• 2000

Two compounds were isolated from the root of Astragalus membranaceus(Bunge). On the basis of spectroscopic data their structures were identified as stigmast-4-en-3-one and a mixture of 2'-angeloyloxy-1',2'-dihydroxanthyletin and 2'-senecioyloxy-1',2'-dihydroxanthyletin. They were first isolated from the genus of Astragalus.

• 생약학회지
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• 제39권3호
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• pp.186-193
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• 2008

Astragali Radix, known as Huangqi, is the most important tonic in the traditional oriental medicine. It reinforces 'qi' (vital energy), strengthens the superficial resistance and promotes the discharge of pus and the growth of new tissue. It has long been used as an anti-perspirant, anti-diuretic or a tonic. Eleven compounds were isolated from the hexane and EtOAc fractions from the roots of Astragalus membranaceus (Leguminosae) and their structures were identified as four triterpenoids [lupenone (1), friedelin (2), lupeol (3), soyasapogenol E (9)] and seven sterols [${\beta}-sitosterol$ (4), stigmastane-3,6-dione (5), $7{\alpha}-hydroxysitosterol$ (6), $5{\alpha},6{\beta}-dihydroxysitosterol$ (7), $7-oxo-{\beta}-sitosterol$ (8), ${\beta}-sitosterol$ glucoside 6'-O-palmitate (10), ${\beta}-sitosterol$ glucoside (11)]. The chemical structures of these compounds were identified on the basis of spectroscopic methods and comparison with literature values. Among these compounds, lupenone (1), friedelin (2), lupeol (3), stigmastane-3,6-dione (5), $7{\alpha}-hydroxysitosterol$ (6), $5{\alpha},6{\beta}-dihydroxysitosterol$ (7), $7-oxo-{\beta}-sitosterol$ (8), soyasapogenol E (9), and ${\beta}-sitosterol$ glucoside 6'-O-palmitate (10) were isolated from this plant for the first time.

• Archives of Pharmacal Research
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• 제26권1호
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• pp.34-39
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• 2003

The traditional Asian medicinal herb, roots of Astragalus (A.) membranaceus (Leguminosae), is used for many purposes, some of which are purported to stimulate the release of growth hormone in vivo. Extracts of A. membranaceus were tested to determine whether they stimulate the release of growth hormone in rat pituitary cell culture. A. membranaceus was extracted sequentially with 80% ethanol (fraction A), n-hexane (fraction B); the test compound from the herbal extraction was isolated using silica gel column chromatography and was identified with spectral data. Test compound was also extracted by traditional boiling water methods. Induction of growth hormone in pituitary cell culture was conducted with isolated compounds and extracted fractions of A. Radix (dried roots of A. membranaceus). The fraction A was not active in the rat pituitary cell culture, but the fraction B derived from the ethanol fraction stimulated the release of growth hormone in culture. Six compounds from fraction B (1-6) were isolated and identified previously. The compounds 1,2-benzendicarboxylic acid diisononylester (1), $\beta$-sitosterol (2), and 3-Ο-$\beta$-D-galactopyranosyl-$\beta$-sitosterol (5) did not induce growth hormone release in the culture. Formononetin (3), 9Z, 12Z-octadecadienoic acid (4), stigmast-4-en-6$\beta$-o1-3-one (6) and 98-E, a mixture of 1'-9, 12-octadecadienoic acid (Z,Z)-2',3'-dihydroxy-propylester (7) and 1'-hexadecanoic acid-2',3'-dihydroxy-propylester (8) stimulated the release of growth hormone in the rat pituitary cell culture significantly compared to the control. In conclusions, four compounds isolated from extracts of A. Radix induced growth hormone release in the rat pituitary cell culture. The 98-E isolate was the most active inducer of growth hormone release.