• 대한핵의학회지
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• 제37권4호
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• pp.235-244
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• 2003

목적: 주의력결핍 과잉행동장애 (Attention Deficit Hyperactivity disorder : 이하 ADHD)는 도파민계의 이상 기능으로 생기는 대표적 소아정신과 질환이다. Methylphenidate는 dopamine transporter(DAT)를 차단함으로써 ADHD 증상을 호전시키는 약물로 널리 알려져 있다. 따라서 본 연구에서는 ADHD 아동들을 대상으로 I-123 IPT SPECT를 이용하여 methylphenidate 투여 전후의 DAT density 양상을 비교해 보고자 한다. 대상 및 방법: 연구대상은 9명의 ADHD 아동과 7명의 정상 대조군이었다. ADHD 아동군과 정상 대조군에게 모두 약물 비노출 상태에서 $[^{123}I]IPT$를 정맥 주사후 2시간이 경과한 상태에서 SPECT를 촬영하였다. 이후 ADHD 아동군을 대상으로 methylphenidate 0.7mg/kg/d을 투여한 후 약 8주가 경과한 상태에서 $[^{123}I]IPT$ SPECT를 재촬영 하였다. Methylphenidate 투여 전과 후의 좌, 우측 기저 신경절 DAT 특이결합/비특이결합 비율을 구한 뒤 비교하였고, 약물 투여 후의 ADHD 증상 척도로 측정한 증상 호전도와 좌, 우측 기저 신경절 DAT 특이결합/비특이결합 비율 변화사이의 상관관계를 알아보았다. 결과: ADHD 아동군에서 약물 비노출 상태와 정상 대조군 사이의 좌, 우측 기저 신경절 DAT특이결합/비특이결합 비율을 비교한 결과 DAT 결합 비율이 정상 대조군에 비해서 유의하게 증가되었다. (Right : z=2.057, p=0.041 ; Left z=2.096, p=0.032). 또한 ADHD 아동들에게 methylphenidate 투여 전과 후 상태에서의 기저 신경절 DAT 특이결합/비특이결합 비율을 비교한 결과, methylphenidate 투여 후 상태가 methylphenidate 투여 전 상태에 비해 좌, 우측 DAT 결합비율이 유의하게 낮아진 것을 관찰할 수 있었다. (우측 : t=3.239, p=0.018 ; 좌측 : t=3.133, p=0.020). ADHD 증상의 호전도와 좌, 우측 기저 신경절 DAT 특이결합/비특이결합 비율 변하사이에는 유의한 상관관계를 보이지 않았다. 결론: 이러한 결과는 주의력결핍 과잉행동장애의 치료제인 methylphenidate가 작용하는 기전을 이용하여 주의력결핍 과잉행동장애의 병태생리와 연관된 도파민계 기능이상 가능성을 지지한다고 생각된다.

• 대한치과의사협회지
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• 제49권4호
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• pp.211-218
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• 2011

Purpose: An impacted tooth is defined as a tooth that shows delayed eruption and is expected to erupt incompletely by clinical and radiograph examination despite it reaching its expected time of eruption. The aims of this study were to investigate the clinical and radiological characteristics and treatment duration and method of impacted teeth in Korean patients. Materials and Methods: For this study we used clinical records, study models, panoramic radiographs and intraoral photographs of patients who attended Gachon University Gil Hospital Orthodontic Department between 2005 and 2008. There were 164 patients with a total number of 202 impacted teeth. Results: Male patients shows a little more prevalence than female patients (1.13:1). The under 12 age group had the highest prevalence of tooth impaction, and the over 19 age group showed the least prevalence of tooth impaction. The ratio of tooth impaction between the left to right ratio was 1.73:1 and maxilla and mandible was 1.84:1. The impacted teeth were most commonly positioned buccally (76 cases, 41.5%). Full nap closure technique (108 cases, 81.2%)was most frequently used for attachment of surgical traction hooks. Maxillary canine impaction was most commonly encountered both in male and female patients. The mean treatment period was 12.2 months and the success rate of treatment was 90.3%. The canine tooth shows the longest treatment time and highest failure rate. The ankylosis was the major cause of failure. Conclusion: Impacted teeth most commonly show in left side maxilla in the under 12 age group. And it is most commonly positioned buccally. The mean treatment period was 12.2 months, and the success rate of treatment was 90.3%.

• 대한의용생체공학회:의공학회지
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• 제30권6호
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• pp.521-528
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• 2009

This study is about to evaluation of postural stability according to characteristics of electrical stimulation on the ankle muscles. We measured body sway(center of pressure, COP) when various parameters of electrical stimulation was applied to ankle muscles in stable and unstable posture. Subjects consisted of 10 young adults, and electrical stimulation was delivered on right and left of tibialis anterior and Achilles tendon. The body sway was measured during electrical stimulation of three duty cycle and frequencies in stable posture and three amplitudes of sensory threshold in unstable posture. Consequently, the COP Shift is higher during electrical stimulation of 1/30(duty ratio) and 100Hz(frequency) in stable posture. In unstable posture, 100% amplitude of sensory threshold induced postural stability. These findings are important for the rehabilitation system of postural stability and the use of electrical stimulation as somatosensory information.

• Journal of Chest Surgery
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• 제29권9호
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• pp.945-950
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• 1996

경북대학교병원 흉부외과학교실에서 1982년 4월부터 1995년 3월사이에 개심술을 시행하였던 좌심실-우심방 단락 12례에 대한 치료경험을 보고한다. 환자들의 연령은 3세에서 26세까지로, 평균연령은 8.5세 이 었고, 성별은 남자가 7명, 여자가 5명이었다. 술전의 단순흉부 X-선소견상 심흉비의 평균치는 0.59이었고, 폐혈관음영의 증가가 3례, 우심방의 확장이 4례에서 있었다. 기록을 확인할 수 있었던 9례에서의 술전 심초음파검사소견에 의하면, 진단명은 좌심실-우심방 단락 2례, 심실중격결손 6례 및 심방중격 결손 1례로 되어 있었다. 따라서 이 검사에 의한 좌심실-우심방판락의 진단률은 22.2%(219)였다. 술전의 심혈 관조영소견으로는, 좌심실-우심방 단락 5례, 심실중격결손 5례, 심방중격결손 1례, 그리고 심실중격 결손 및 심방중격결손 1례로 진단되었다. 그러므로 이 검사에 의한 진단률은 41.6% (5112)였다. 수술소견상, 좌심실-우심방 단락의 형태는 판막상부형 결손 5례(42%), 판막하부형 결손4례(33%)및 복합형 결손3 례 (25%)로 분류되었다. 한편 판막하부형 결손례들은 모두 삼첨 판막 중격엽의 이상을 동반하고 있었는데, 즉 천공이 3례, 구열\ulcorner 1례에서 있었다. 그러나 판막상부형이나 복합형 결손에서는 삼첨판의 이상은 볼 수 없었다. 수술은 1례를 제외하고는 모두 우심방절개하에 결손부의 일차봉합을 시행하였고, 수술사 망례는 없었다. 그러나 잔존 심실중격 결손이 1례에서 발견되어 술후 6개월에 재수술을 시행하여 완치되었다. 그밖의 환자들에서의 술후 경과는 모두 양호하였다.

• 한국안전학회지
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• 제25권3호
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• pp.15-21
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• 2010

A differential case equipped with LSD(limited slip differential) has several advantages over a normal type for rear wheel drive vehicles. Specially, the torque distribution can be done between left and right drive wheel in the state of limited slip differential. Also although LSD types are very various according to operating type, medium and torque distribution, a multi-clutch type is generally applied to rear wheel drive vehicles. So, this study presents the analysis of design parameters for development of a friction plate for multi-clutch type LSD using vehicle road test, the simulation of analytical model and the development of vehicle dynamics model by a benchmark product. According to this investigation, the design parameters which are pre-load of coil spring, friction plate and contact area quantity, friction coefficient and TBR(torque bias ratio) for a friction plate are derived from experiment and simulation and consequently, vehicle dynamics model has been constructed for the development of friction plate for multi-clutch type LSD.

• 방사선산업학회지
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• 제10권4호
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• pp.193-198
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• 2016

Perfusion magnetic resonance image of biological mechanism are independent of magnetic field strength in hyper acute ischemic stroke. 3.0 T magnetic field, however, does affect the SNRs (signal to noise ratio) and artifacts of PMRI (perfusion magnetic resonance image), which basically will influence the quantitative of PMRI. In this study, the effects of field strength on PMRI are analyzed. The effects of the diseases also are discussed. PMRI in WM(white matter), GM (gray matter), hyper acute ischemic stroke were companied with 1.5 T and 3.0 T on SNR. PMRI also was compared to the SI difference after setting ROI(region of interest) in left and right side of the brain. In conclusion, the SNRs and SI of the 3.0 T PMRI showed higher than those at 1.5 T. In summary, PMRI studies at 3.0 T is provided significantly improved perfusion evaluation when comparing with 1.5 T.

• Radiation Oncology Journal
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• 제12권3호
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• pp.387-392
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• 1994

Purpose : This study was done to confirm the reference point variation according to variation in applicator configuration in each fractioation of HDR ICR. Materials and Methods : We analyzed the treatment planning of HDRICR for 33 uterine cervical cancer patients treated in department of therapeutic radiology from January 1992 to February 1992. Analysis was done with respect to three view points-Interfractionation A point variation, interfractionation bladder and rectum dose ratio variation, interfractionation treatment volume variation. Interfractionation A point variation was defined as difference between maximum and minimum distance from fixed rectal point to A point in each patient. Interfractionation bladder and rectum dose ratio variation was defined as difference between maximum and minimum dose ratio of bladder or rectum to A point dose in each patient, Interfractionation treatment volume variation was defined as difference between miximum and minimum treatment volume which absorbed over the described dose-that is, 350 cGy or 400 cGy-in each patient. Results The mean of distance from rectum to A point was 4.44cm, and the mean of interfractionation distance variation was 1.14 cm in right side,1.09 cm in left side. The mean of bladder and rectum dose ratio was $63.8\%$ and $63.1\%$ and the mean of interfractionation variation was $14.9\%$ and $15.8\%$ respectively. With fixed planning administration of same planning to all fractionations as in first fractionation planning-mean of bladder and rectum dose ratio was $64.9\%$ and $72.3\%$.and the mean of interfraction variation was $28.1\%$ and $48.1\%$ reapectively. The mean of treatment volume was $84.15cm^3$ and the interfractionation variation was $21.47cm^2$. Conclusion : From these data, it was confirmed that there should be adapted planning for every fractionation ,and that confirmation device installed in ICR room would reduce the interfractionation variation due to more stable applicator configuration.

• 한국멀티미디어학회논문지
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• 제19권5호
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• pp.881-889
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• 2016

Ocular region recently emerged as a new biometric trait for overcoming the limitations of iris recognition performance at the situation that cannot expect high user cooperation, because the acquisition of an ocular image does not require high user cooperation and close capture unlike an iris image. This study proposes a new method for ocular image recognition based on BRISK (binary robust invariant scalable keypoints). It uses the distance ratio of the two nearest neighbors to improve the accuracy of the detection of corresponding keypoint pairs, and it also uses geometric constraint for eliminating incorrect keypoint pairs. Experiments for evaluating the validity the proposed method were performed on MMU public database. The person recognition rate on left and right ocular image datasets showed 91.1% and 90.6% respectively. The performance represents about 5% higher accuracy than the SIFT-based method which has been widely used in a biometric field.

• Journal of Chest Surgery
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• 제15권3호
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• pp.274-277
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• 1982

A Clinical analysis of 59 patients of thoracic empyema was done who were received surgical intervention at dept. of thoracic surgery of the C.A.F.G.H. in the period of 2.5 years from January 1979 to June 1982. Occurrence ratio of Left and Right side pleural cavity of empyema was 1: 1.4. The predisposing factors of empyema were pulmonary Tbc. [49%], Chest pain [25%], Cough [8%], in order. B.P.F. was associated with empyema in 5 cases. The pleural cavity empyema was treated with several surgical procedures and conservative measures. Among of the 59 cases, the 30 cases [50%] were treated with decortication, 12 cases [20%] with closed thoractomy drainage, 9 cases with frequent thoracenteses, 5 cases with partial decortication and thoracoplasty and 3 cases with open thoracostomy tube drainage. Among of the 59 cases thoracic empyema, the full recovery were in 32 cases [54%], partial recovery in 20 cases [34%], not improved in 3 cases [5%] and 3 cases were died. The mortality rate was 5% and the recovery rate was 89%.

• 대한인간공학회지
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• 제35권5호
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• pp.403-411
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• 2016

Objective: This study is concerned with the user interface (UI) design of touch screen based on the reaction time of Automated Teller Machine (ATM) user. Background: Adopting the touch screen technology, the ATM service has recently established a new user interface different from the existing button-type interface. Method: Experiments were conducted by simulating ATM touch screen layouts, and layouts were focused on location of menu buttons (left and right, top and bottom), number of menu buttons (8 and 12 buttons). Results: The results show that there are significant differences in correction ratio and reaction time by user groups, types of menu location, and the number of buttons. Conclusion and Applications: The results of this study can be used to provide baseline information for the interface design of ATM touch screen and the age differences in reaction time.