• 한국분말재료학회지
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• 제26권5호
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• pp.421-431
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• 2019

In this study, the formation, microstructure, and wear properties of Colmonoy 88 (Ni-17W-15Cr-3B-4Si wt.%) + Stellite 1 (Co-32Cr-17W wt.%) coating layers fabricated by high-velocity oxygen fuel (HVOF) spraying are investigated. Colmonoy 88 and Stellite 1 powders were mixed at a ratio of 1:0 and 5:5 vol.%. HVOF sprayed self-fluxing composite coating layers were fabricated using the mixed powder feedstocks. The microstructures and wear properties of the composite coating layers are controlled via a high-frequency heat treatment. The two coating layers are composed of ${\gamma}-Ni$, $Ni_3B$, $W_2B$, and $Cr_{23}C_6$ phases. Co peaks are detected after the addition of Stellite 1 powder. Moreover, the WCrB2 hard phase is detected in all coating layers after the high-frequency heat treatment. Porosities were changed from 0.44% (Colmonoy 88) to 3.89% (Colmonoy 88 + ST#1) as the content of Stellite 1 powder increased. And porosity is denoted as 0.3% or less by inducing high-frequency heat treatment. The wear results confirm that the wear property significantly improves after the high-frequency heat treatment, because of the presence of well-controlled defects in the coating layers. The wear surfaces of the coated layers are observed and a wear mechanism for the Ni-based self-fluxing composite coating layers is proposed.

• Asian-Australasian Journal of Animal Sciences
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• 제32권11호
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• pp.1715-1724
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• 2019

Objective: As laying hens become aged, laying performance and egg quality are generally impaired. One of the practical methods to rejuvenate production and egg quality of aged laying hens with decreasing productivity is a forced molting. However, the changes in intestinal microbiota after forced molting of aged hens are not clearly known. The aim of the present study was to analyze the changes in excreta bacterial communities after forced molting of aged laying hens. Methods: A total of one hundred 66-wk-old Hy-Line Brown laying hens were induced to molt by a 2-d water removal and an 11-d fasting until egg production completely ceased. The excreta samples of 16 hens with similar body weight were collected before and immediately after molting. Excreta bacterial communities were analyzed by high-throughput sequencing of bacterial 16S rRNA genes. Results: Bacteroidetes, Firmicutes, and Proteobacteria were the three major bacterial phyla in pre-molting and immediate post-molting hens, accounting for more than 98.0%. Lactobacillus genus had relatively high abundance in both group, but decreased by molting (62.3% in premolting and 24.9% in post-molting hens). Moreover, pathogenic bacteria such as Enterococcus cecorum and Escherichia coli were more abundant in immediate post-molting hens than in pre-molting hens. Forced molting influenced the alpha diversity, with higher Chao1 (p = 0.012), phylogenetic diversity whole tree (p = 0.014), observed operational taxonomic unit indices (p = 0.006), and Simpson indices (p<0.001), which indicated that forced molting increased excreta bacterial richness of aged laying hens. Conclusion: This study improves the current knowledge of bacterial community alterations in the excreta by forced molting in aged laying hens, which can provide increasing opportunity to develop novel dietary and management skills for improving the gastrointestinal health of aged laying hens after molting.

• 한국균학회지
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• 제47권3호
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• pp.219-232
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• 2019

Chemicals related to hydrogen peroxide ($H_2O_2$) and nitric oxide (NO) generations were exogenously applied to Fusarium oxysporum f. sp. fragariae (Fof) causing Fusarium wilt disease in strawberry plants, and regulations of in vitro conidial germination and mycelial growth of the fungus by the chemical treatments were evaluated. $H_2O_2$ drastically reduced the conidial germination of Fof in a dose-dependent manner, and treatment with 3-amino-1,2,4-triazole (3-AT) catalase inhibitor also led to dose-dependent inhibition of conidial germination but relatively moderately. Gradual decreases in mycelial growth of Fof were found by high concentrations of $H_2O_2$, whilst exogenous 3-AT slightly increased the mycelial growth. Increasing sodium nitroprusside (SNP) NO donor, $N^G$-nitro-l-arginine methyl ester (L-NAME) NO synthase (NOS)-inhibitor and tungstate nitrate reductase (NR) inhibitor led to dose-dependent reductions in conidial germination of Fof in quite different levels. SNP conversely increased the mycelial growth but increasing L-NAME moderately decreased the mycelial growth. Tungstate strongly enhanced mycelial growth. Differentially regulated in vitro mycelial growths of Fof were demonstrated by SNP, L-NAME and tungstate with or without $H_2O_2$ supplement. Superoxide anion production was also regulated during the mycelial growth of Fof by nitric oxide. These results show that $H_2O_2$ and NO-associated enzymes can be suggested as fungal growth regulators of Fof as well as eco-friendly disease-managing agents in strawberry production fields.

• 한국환경복원기술학회지
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• 제24권2호
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• pp.71-84
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• 2021

Restoration of DMZ has come up with the discussion on the peaceful use of the DMZ and the conservation plan of the army. In this study, we aim to identify soil characteristics of 108 sites to figure out environmental conditions around the iron fence of DMZ where vegetation has been removed repeatedly. Based on the soil characteristics and climate variables, hierarchy clustering was performed to categorize sites. As a result, we categorized 108 sites into 4 types: middle elevation region, lowland, East coast lowland, other areas. Group of 'other area' is only high in nutrient and clay proportion. Others are in igneous rock and metamorphic rocks with a high proportion of sand and lower nutrients than the optimum range of growth in Korean forest soil. The middle elevation region has a high altitude, low temperature. The east coast lowland has a high temperature in January and low precipitation. The lowland has a low altitude and high temperature. This category provides the environmental condition around the DMZ fence and can be used to select plants for restoration. The restoration project around the DMZ iron fence should satisfy the security of military plans, which means that functional restoration is prior to ecological restoration such as vegetation management under a power line. Additionally, improvement of soil quality and surface stability through restoration projects is required to enhance the resilience of the ecosystem in DMZ.

• 대한임상독성학회지
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• 제19권2호
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• pp.93-99
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• 2021

Purpose: Nutritional status and support in critically ill patients are important factors in determining patient recovery and prognosis. The aim of this study was to analyze the early nutritional status and the methods of nutritional support in critically ill patients with acute poisoning and to evaluate the effect of nutritional status on prognosis. Methods: A retrospective study was conducted in tertiary care teaching hospital from January 2018 to December 2020. in an emergency department of university hospital, 220 patients who were stayed more than 2 days of poisoning in intensive care unit were enrolled. Results: 155 (70.5%) of patients with acute poisoning had low-risk in nutritional risk screening (NRS). Patients with malignancy had higher NRS (low risk 5.2%, moderate risk 18.5%, high risk 13.2%, p=0.024). Patients of 91.4% supplied nutrition via oral route or enteral route. Parenteral route for starting method of nutritional support were higher in patients with acute poisoning of herbicide or pesticide (medicine 3.2%, herbicide 13.8%, pesticide 22.2%, p=0.000). In multivariate logistic regression analysis, herbicide or pesticide intoxication, higher risk in NRS and sequential organ failure assessment over 4.5 were affecting factor on poor recovery at discharge. Conclusion: NRS in patients intoxicated with herbicide or pesticide were higher than that in patients intoxicated with medicine intoxication. Enteral nutrition in patients intoxicated with herbicide or pesticide was less common. Initial NRS was correlated with recovery at discharge in patient with intoxication. It is expected to be helpful in finding patients with high-risk nutritional status in acute poisoning patients and establishing a treatment plan that can actively implement nutritional support.

• 방사선산업학회지
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• 제12권4호
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• pp.355-363
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• 2018

A novel $N_3S_1$ chelate, Pro-Lys-Cys (PKC) to cyclic RGD to radiolabel with $^{99m}Tc$ was conjugated in an effort to decrease the high intestinal accumulation observed for $^{99m}Tc$-labeled PGC-RGD. The target specificity of the resulting PKC-RGD was similar to that of PGC-RGD as determined by a cell binding assay and a competition binding assay. The $^{99m}Tc$ radiolabeling of PKC-RGD resulted in radiochemical yields of 98% under mild conditions at high specific activities. Biodistribution data in normal mice clearly showed a significant decrease in intestinal uptake at 2 h postinjection for the $^{99m}Tc-PKC-c$ (RGDyK) compared to the $^{99m}Tc-GC-c$ (RGDyK) (from $19.65%ID{\cdot}g^{-1}$ to $7.31%ID{\cdot}g^{-1}$ for the GI tract). The $^{99m}Tc-PKC-c$ (RGDyK) biodistribution was also shown by a higher retention of radioactivity in the whole body, but with kidney accumulation over 8-fold higher than observed with $^{99m}Tc-PGC-c$ (RGDyK) at 2 h ($12.62%ID{\cdot}g^{-1}$ for PKC-RGD and $1.54%ID{\cdot}g^{-1}$ for PGC-RGD, respectively). These results show that the biodistribution may be altered especially concerning lipophilicity resulting in renal rather than hepatobiliary excretion. This comparative study made it possible to explore the effects of lipophilicity on the biodistribution of $^{99m}Tc$-labeled c (RGDyK) through the use of different tripeptide $N_3S_1$ chelators. Therefore, $^{99m}Tc-PKC-c$ (RGDyK) may be an attractive alternative for the in vivo imaging of integrin receptors.

• 척추신경추나의학회지
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• 제14권1호
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• pp.49-59
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• 2019

본 증례에서는 넘어진 후 상완골 골절 진단 하에 수술하였으나 뒤늦게 원위 요척관절 탈구로 진단되어 1차 수술 후 정복 소실되어 Sauve-Kapandji 수술받은 환자를 대상으로 한방재활치료를 약 3주간 시행하였다. 관절가동추나, 침 치료, 한약물 치료 등 한방재활치료 결과 우측 팔꿈치, 손목, 손가락 관절 가동범위, 수술부위 통증, 근력, 상지 기능 등에서 의미 있는 호전을 보였다. 본 연구는 단일 증례 보고라는 한계가 있으나, 한방재활치료가 수술 후 환자의 전반적인 경과에 효과적으로 작용하였기에 보고하는 바이다.

• 스트레스연구
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• 제26권4호
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• pp.277-289
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• 2018

본 연구는 일반인이 경험하는 일상우울 상태를 손쉽게 판단할 수 있는 개인선별용 검사를 제작하고 신뢰도와 타당도를 조사하는데 목적이 있다. 이를 위해 원척도인 일상우울 집단연구용 척도(17문항)를 바탕으로 5문항으로 된 단축형 척도를 개발하였다. 연구 결과, 집단연구용 척도와 단축형 척도 간 상관은 .94로 높았으며, 검사-재검사 신뢰도(60일 이내 .73) 또한 양호한 수준이었다. 검사의 내적 구조는 1요인으로 확인되었다. 끝으로 기준점수를 구하였는데, 단축형 5개 문항의 총점이 18점 이상이면 일상우울 수준을 넘어 역기능우울의 가능성이 있으므로 역기능우울척도를 실시하는 것을 권고한다.

• 한국추진공학회지
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• 제22권5호
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• pp.22-31
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• 2018

본 연구에서는 연소실 경계조건 변화에 따른 핀틀 노즐의 동특성을 파악하기 위해 수치해석을 수행하였다. 핀틀의 움직임을 모사하기 위해 노즐과 핀틀의 영역을 분리하여 격자를 생성하고 중첩격자기법을 사용하였다. 연소실의 경계조건은 일정질량유량과 추진제 연소속도 조건을 적용하여 결과를 비교하였다. 일정질량유량조건은 입구에 유입되는 질량유량을 정량적으로 변화시켜 연소실의 압력과 추력 특성을 파악하였다. 추진제 연소속도 조건은 연소실 압력에 의한 연소속도 식을 고려하였다. 추진제 연소속도 조건은 일정질량유량조건과는 다른 비선형적 유량변화를 나타내며, 작은 유량으로도 큰 연소실 압력변화를 가져온다.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2016년도 추계학술대회
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• pp.663-664
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• 2016

해수를 이용한 온도차 발전은 심층수와 표층수의 온도 차이를 이용한 암모니아(냉매)를 사용하여 폐쇄적인 액화와 기화를 반복하여 터빈을 돌리는 방식이다. 온도차 발전의 특성상 온도 차이가 클수록 에너지 발전 특성은 좋아진다. 이는 심층수 표층수의 온도차이가 커야 됨을 이야기 한다. 하지만 겨울이 되면 표층수와 심층수의 온도차이가 크지 않아 에너지 효율이 떨어지는 문제점이 있다. 그리고 해수 담수화기술은 지구의 97%를 차지하지만 우리가 먹을 수 없는 바닷물을 담수로 바꾸는 기술로, 해수 담수화기술로 생산된 담수는 선박내의 공업, 식수 등 각종 용수로 사용할 수 있다. 본 논문에서는 현재 문제가 되고 있는 계절에 따른 표층수의 온도 변화를 개선하기 위해 기존에 사용하고 있는 선박용 디젤엔진의 열에너지와 LNG의 냉열 에너지를 사용한 온도차 발전을 위해 LNG 운송 선박을 기준으로 LNG 운송 선박 하이브리드 엔진에 관한 연구와 냉열 에너지를 활용한 해수 냉동법으로 담수화하는 발전 및 담수화를 복합시킨 연구를 제시하고자 한다.