• Title/Summary/Keyword: Lee Sang Hyuk

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Korean Society of Heart Failure Guidelines for the Management of Heart Failure: Management of the Underlying Etiologies and Comorbidities of Heart Failure

  • Sang Min Park;Soo Youn Lee;Mi-Hyang Jung;Jong-Chan Youn;Darae Kim;Jae Yeong Cho;Dong-Hyuk Cho;Junho Hyun;Hyun-Jai Cho;Seong-Mi Park;Jin-Oh Choi;Wook-Jin Chung;Seok-Min Kang;Byung-Su Yoo;Committee of Clinical Practice Guidelines, Korean Society of Heart Failure
    • Korean Circulation Journal
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    • v.53 no.7
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    • pp.425-451
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    • 2023
  • Most patients with heart failure (HF) have multiple comorbidities, which impact their quality of life, aggravate HF, and increase mortality. Cardiovascular comorbidities include systemic and pulmonary hypertension, ischemic and valvular heart diseases, and atrial fibrillation. Non-cardiovascular comorbidities include diabetes mellitus (DM), chronic kidney and pulmonary diseases, iron deficiency and anemia, and sleep apnea. In patients with HF with hypertension and left ventricular hypertrophy, renin-angiotensin system inhibitors combined with calcium channel blockers and/or diuretics is an effective treatment regimen. Measurement of pulmonary vascular resistance via right heart catheterization is recommended for patients with HF considered suitable for implantation of mechanical circulatory support devices or as heart transplantation candidates. Coronary angiography remains the gold standard for the diagnosis and reperfusion in patients with HF and angina pectoris refractory to antianginal medications. In patients with HF and atrial fibrillation, longterm anticoagulants are recommended according to the CHA2DS2-VASc scores. Valvular heart diseases should be treated medically and/or surgically. In patients with HF and DM, metformin is relatively safer; thiazolidinediones cause fluid retention and should be avoided in patients with HF and dyspnea. In renal insufficiency, both volume status and cardiac performance are important for therapy guidance. In patients with HF and pulmonary disease, beta-blockers are underused, which may be related to increased mortality. In patients with HF and anemia, iron supplementation can help improve symptoms. In obstructive sleep apnea, continuous positive airway pressure therapy helps avoid severe nocturnal hypoxia. Appropriate management of comorbidities is important for improving clinical outcomes in patients with HF.

Analysis and implications of North Korea's new strategic drones 'Satbyol-4', 'Satbyol-9' (북한의 신형 전략 무인기 '샛별-4형', '샛별-9형' 분석과 시사점)

  • Kang-Il Seo;Jong-Hoon Kim;Man-Hee Won;Dong-Min Lee;Jae-Hyung Bae;Sang-Hyuk Park
    • The Journal of the Convergence on Culture Technology
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    • v.10 no.2
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    • pp.167-172
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    • 2024
  • In major wars of the 21st century, drones are expanding beyond surveillance and reconnaissance to include land and air as well as sea and underwater for purposes such as precision strikes, suicide attacks, and cognitive warfare. These drones will perform multi-domain operations, and to this end, they will continue to develop by improving the level of autonomy and strengthening scalability based on the High-Low Mix concept. Recently, drones have been used as a major means in major wars around the world, and there seems to be a good chance that they will evolve into game changers in the future. North Korea has also been making significant efforts to operate reconnaissance and attack drones for a long time. North Korea has recently continued to engage in provocations using drones, and its capabilities are gradually becoming more sophisticated. In addition, with the recent emergence of new strategic Drones, wartime and peacetime threats such as North Korea's use of these to secure surveillance, reconnaissance and early warning capabilities against South Korea and new types of provocations are expected to be strengthened. Through this study, we hope to provide implications by analyzing the capabilities of North Korea's strategic Drones, predicting their operation patterns, and conducting active follow-up research on the establishment of a comprehensive strategy, such as our military's drone deployment and counter-drone system solutions.

Vegetation Structure and Ecological Characteristic of Bulgapsan Provincial Park (불갑산도립공원의 식생구조 및 생태적 특성)

  • Jeong-Hyun Ki;Sang-Cheol Lee;Jae-Hyuk Yoo;Hyun-Mi Kang
    • Korean Journal of Environment and Ecology
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    • v.38 no.3
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    • pp.310-323
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    • 2024
  • The purpose of this study was to understand the vegetation structure and ecological characteristic of Bulgapsan(Mt.) Provincial Park by setting up and surveying 64 plots(100m2). The analysis using the TWINSPAN and DCA techniques found seven community groups: Pinus densiflora-Quercus variabilis community, P. densiflora-P. rigida-Q. serrata community, Q. variabilis-Carpinus tschonoskii community, Q. aliena-Q. variabilis-Cornus controversa community, Q. aliena-Platycarya strobilacea community, Broad-leaved miced community and Q. variabilis community. The result of vegetation community structure analysis showed that P. densiflora community and deciduous Quercus spp. community were in competition, and succession to Quercus spp. community was expected. In the case of other broad-leaved forests, the current status is expected to be maintained. But continuous monitoring is required in areas where Neolitsea sericea and Cephalotaxus appear, which grow naturally in warm temperate forest and southern temperate vegetation zone. Species diversity by communities are confirmed to be highest at 2.6654 in the actively competitive P. densiflora-P. rigida-Q. serrata community, and the lowest in the Deciduous broad-leaved forests community at 1.2548. The results of the tree rings and annual growth analysis showed that dominant trees had an average age of more than 37~87 years. Among them, N. sericea designated as a natural monument was 48~56 years old.

A Study on the Characteristics Measurement of Main Engine Exhaust Emission in Training Ship HANBADA (실습선 한바다호 주기관 배기가스 배출물질 특성 고찰에 관한 연구)

  • Choi, Jung-Sik;Lee, Sang-Deuk;Kim, Seong-Yun;Lee, Kyoung-Woo;Chun, Kang-Woo;Nam, Youn-Woo;Jung, Kyun-Sik;Park, Sang-Kyun;Choi, Jae-Hyuk
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.19 no.6
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    • pp.658-665
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    • 2013
  • In this study, we measured particulate matter(PM) which emerged as the hot issue from the International Maritime Organization(IMO) and the exhaust emission using HANBADA, the training ship of Korea Maritime University. In particular, the PM was obtained with TEM grid. PM structure was observed by electron microscopy. And exhaust gases such as NOx, $CO_2$, and CO were measured using the combustion gas analyzer(PG-250A, HORIBA). The results of this study are as follows. 1) When the ship departed from the port, the maximum difference in PM emissions were up to 30 % due to the Bunker Change. 2) Under the steady navigation, emission of PM was $1.34mg/m^3$ when Bunker-A is changing L.R.F.O(3 %). And, at the fixed L.R.F.O (3 %), emission of PM was $1.19mg/m^3$. When the main engine RPM increased up to 20 % with fixed L.R.F.O(3 %), emission of PM was $1.40mg/m^3$. When we changed to low quality oil(L.R.F.O(3 %)), CO concentration from main engine increased about 16 %. On the other hand, when the main engine RPM is rising up to 20 %, CO concentration is increased more than 152 percent. These results imply that the changes of RPM is a dominant factor in exhaust emission although fuel oil type is an important factor. 3) The diameter of PM obtained with TEM grid is about $4{\sim}10{\mu}m$ and its structure shows porous aggregate.

Studies on Symbiotic Nitrogen Fixation in Soybean -II. Seasonal Changes of Nodule Development and N2-Fixing activities of Rhizobium japonicum to the Different Varieties of Soybean under Different Soils (대두근류균(大豆根瘤菌)의 질소고정(窒素固定)에 관(関)한 연구(硏究) -II. 상이(相異)한 토양(土壌)에서 대두품종별(大豆品種別) 근류(根瘤)의 발달양상(発達樣相) 및 질소고정(窒素固定)에 관(関)한 연구(硏究))

  • Ryu, Jin-Chang;Lee, Sang-Kyu;Lee, Hyuk-Ho;Hong, Chong-Woon;Cho, Moo-Je
    • Korean Journal of Soil Science and Fertilizer
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    • v.16 no.1
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    • pp.84-91
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    • 1983
  • These experiment were conducted to investigate the seasonal changes of nodule formation and $N_2$-fixing activitues of soybean root nodules which grown in pot on five cultivars in different soils. The results obtained were as follows; 1. It was found that the development of nodules starts from 20 days after planting and continues to increase up to 50-60 days after planting. 2. $N_2$-fixing activities were different with cultivars of soybean. The trend was high in order H-25 > Suweon 63 > Hill > Yugwoo 3# > Gwanggyo 3. Rhizobium japonicum isolated from different soybean cultivars showed different acetylene reducing activities in vitro ; high in order A62-1 > Suweon 63 > Hill > Gwanggyo > Yugwoo 3#.

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Trend (in 2005) of Repair of Inguinal Hernia in Children in Korea - A National Survey by the Korean Association of Pediatric Surgeons in 2005 - (2005년도 소아 서혜부 탈장치료 경향)

  • Kim, Seong-Min;Kim, Dae-Yeon;Kim, Sang-Yoon;Kim, Seong-Chul;Kim, Woo-Ki;Kim, Jae-Eok;Kim, Jae-Chun;Park, Kwi-Won;Seo, Jeong-Meen;Song, Young-Tack;Oh, Jung-Tak;Lee, Nam-Hyuk;Lee, Doo-Sun;Chun, Yong-Soon;Chung, Sang-Young;Chung, Eul-Sam;Choi, Kum-Ja;Choi, Soon-Ok;Han, Seok-Joo;Huh, Young-Soo;Hong, Jeong;Choi, Seung-Hoon
    • Advances in pediatric surgery
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    • v.12 no.2
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    • pp.155-166
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    • 2006
  • Inguinal hernia is the most common disease treated by the pediatric surgeon. There are several controversial aspects of management 1)the optimal timing of surgical repair, especially for preterm babies, 2)contralateral groin exploration during repair of a clinically unilateral hernia, 3)use of laparoscope in contralateral groin exploration, 4)timing of surgical repair of cord hydrocele, 5)perioperative pain control, 6)perioperative management of anemia. In this survey, we attempted to determine the approach of members of KAPS to these aspects of hernia treatment. A questionnaire by e-mail or FAX was sent to all members. The content of the questionnaire were adapted from the "American Academy of Pediatrics (AAP) Section on Surgery hernia survey revisited (J Pediatr Surg 40, 1009-1014, 2005)". For full-term male baby, most surgeons (85.7 %) perform an elective operation as soon as diagnosis was made. For reducible hernia found in ex-preterm infants already discharged from the neonatal intensive care unit (NICU), 76.2 % of surgeons performed an elective repair under general anesthesia (85.8 %). 42.9 % of the surgeons performed the repair just before discharge. For same-day surgery for the ex-premature baby, the opinion was evenly divided. For an inguinal hernia with a contralateral undescended testis in a preterm baby, 61.9 % of surgeons choose to 'wait and see' until 12 month of age. The most important consideration in deciding the timing of surgery of inguinal hernia in preterm baby was the existence of bronchopulmonary dysplasia (82.4 %), episode of apnea/bradycardia on home monitoring (70.6 %). Most surgeons do not explore the contralateral groin during unilateral hernia repair. Laparoscope has not been tried. Most surgeons do not give perioperative analgesics or blood transfusion.

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Change of FDG Uptake According to Radiation Dose on Squamous Cell Carcinoma of the Head and Neck (두경부종양에서 방사선조사량에 타른 FDG-PET의 변화양상)

  • Lee Sang-wook;Kim Jae-Seung;Im Ki Chun;Ryu Jin Sook;Lee Hee Kwan;Kim Jong Hoon;Ahn Seung Do;Shin Seong Soo;Yoon Sang Min;Song Siyeol;Park Jin-hong;Moon Dae Hyuk;Choi Eun Kyung
    • Radiation Oncology Journal
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    • v.22 no.2
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    • pp.98-105
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    • 2004
  • Purpose : To evaluate whether positron omission tomography (PET) with 2-[F-18]fluoro-2-deoxy-D-giucose(FDG) can be used to predict of early response to definitive aim radlotherapy (RT) in squamous cell carcinoma of the head and neck using response rate and locoreglonal control as study endpoints. Materials and Methods : Twenty-two patients with head and neck cancer underwent a FDG-PET study before RT, after a flrst dose of 45 Gy, and after a second dose on more 4han 70 Gy. Standard uptake value (SUV) was calculated for primary tumor (n=22) and neck lymph node (n:10). Attenuation corrected PET scans acquired 60 min after tracer injection were used for evaluation of FDG uptake In tumors. A quantitative FDG uptake index was expressed as Suvlean (corrected for iean body mass). The follow-up time was at least 5 months (range S-1 S months). Results : A total of 22 primary tumors and 10 metastatic lymph nodes were analyzed In FDG-PET. In the first PET study the mean SUVlean the primary tumors and nodes were 5.4 (SD, 2.5) and 4.6 (SD, 2.3), respectively. In the second PET, study peformed after 46 Gy RT the mean SUV in primary tumor and node decreased to 2.9 (SD, 1.9, p<0.001) and 1.7 (SD, 1.3) respectively. in the third PET study peformed at the full dose (more than 70 Gy), RT the mean SUV In the primary tumors and nodes decreased to 2.3 (SD, 1.5, p<0.001) and 1.5 (SD, 1 .1) respectively. Conclusions: FDG uptake In tumors showed a significant decrease after the 45 Gy and more than 70 Gy of RT for squamous cell carcinoma of the head and neck. Reduction of metabolic activity after 46 Gy of radiotherapy Is closely correlated with radiation response.

Prediction of Prognosis to Concurrent Chemo-Radiotherapy by Standardized Uptake Value of $2-[18^F]$ Fluovo-2-Deoxy-D-Glucose for Nasopharyngeal Carcinomas (비인강암 환자의 예후에서 $2-[18^F]$ Fluoro-2-Deoxy-D-Glucose PET 영상에서 계산되는 Standardized Uptake Value의 의의)

  • Lee Sang-wook;Im Ki Chun;Nam Soon Yuhl;Kim Jae Seung;Choi Eun Kyung;Ahn Seung Do;Shin Seong Soo;Ryu Jin Sook;Kim Sang Yoon;Lee Bong-Jae;Choi Seung-Ho;Kim Sung-Bae;Moon Dae Hyuk
    • Radiation Oncology Journal
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    • v.23 no.1
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    • pp.9-16
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    • 2005
  • Purpose : To prospectively evaluate the use of positron emission tomography with the glucose analog fluoro-deoxyglucose (FDG-PET) to deoxyglucose (FDG-PET) to predict disease-free survival (DFS) after concurrent chemo-radiotherapy (CCRT) in patients with non-disseminated nasopharyngeal carcinoma (NPC). Materials and Methods : We studied 41 patients with non-disseminated NPC scheduled to undergo platinum-based CCRT were eligible for this study. Patients were studied by FDG-PET prior to the CCRT. FDG uptake of tumors were measured with the maximal standardized uptake value (SUV). Results : Complete response rate was $100\%$. In ten patients who presented with any component of treatment failure, the median $SUV_{max}$ was 8.55 (range: $2.49\~14.81$) in any component of failure and the median $SUV_{max}$ was 5.48 (range: $2.31\~26.07$) In the remaining patients without any such failure. Patients having tumors with high FDG uptake had a significantly lower 3-year DFS ($51\%\;{\nu}91\%$, p=0.0070) compared with patients having low uptake tumors. Conclusion : FDG uptake, as measured by the SUV, has potential value in predicting DFS in NPC treated by CCRT, High FDG uptake may be a useful parameter for Identifying patients requiring more aggressive treatment approaches.

Assessment of Food Service Management at Childcare Facilities According to the Number of People Eating Meals (식수인원에 따른 보육시설 급식소 위생관리 수준 평가)

  • Dong Soo Kim;Hyuk Sung Kwon;Pyeong Won Kim;Ja Yeong Lee;Sang Gu Kim;Sang Yun Lee
    • Journal of Food Hygiene and Safety
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    • v.39 no.1
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    • pp.26-34
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    • 2024
  • In this study, the food service management levels of cafeterias in childcare facilities were investigated based on the number of meal recipients and the working status of the kitchen staff. The study included 199 childcare facilities nationwide that received food supplies from the food ingredients distribution company, Pulmuone Foodmerce, from 2021 to 2022. The assessment was conducted using 61 inspection items. The analysis revealed that, as the number of meal recipients and kitchen staff members decreased, the documentation of inspection results was less likely to be conducted (P<0.05). Facilities with fewer meal recipients showed less adequate health status checks for kitchen staff, and those with fewer kitchen staff showed insufficient compliance with hygienic clothing (P<0.05). Additionally, facilities with fewer meal recipients showed a higher frequency of lapses in checking the expiration dates of stored ingredients (P<0.05), requiring increased management attention. They also exhibited the absence of internal temperature measurement records during heating processes (P<0.05). Furthermore, facilities with fewer meal recipients demonstrated inadequate maintenance of kitchen facilities (P<0.05). Significantly higher adenosine triphosphate (ATP) levels were detected on the hands and cutting boards of the kitchen staff in facilities with fewer meal recipients and fewer kitchen staff (P>0.05). Overall, facilities with fewer meal recipients exhibited insufficient infrastructure management for kitchen operations and inadequate hygiene management. These results are expected to provide foundational data for the selection of national support programs for childcare facilities in the future.

Two Cases of Hot Tub Lung in Bodyscrubbers Working in a Public Bath (대중목욕탕 근무 후 발생한 온수 욕조 폐 2예)

  • Bak, Ji Young;Kim, Kwang Sil;Park, I-Nae;Yum, Ho-Kee;Lee, Seung Heon;Lee, Hyun-Kyung;Lee, Young Min;Jung, Hoon;Hur, Jin-Won;Lee, Seong Soon;Lee, Hyuk Pyo;Choi, Soo Jeon;Shin, Eun Ah;Choi, Sang Bong
    • Tuberculosis and Respiratory Diseases
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    • v.66 no.1
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    • pp.37-41
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    • 2009
  • Hot tub lung has been described as a pulmonary illness associated with exposure to nontuberculous mycobacteria,mainly hot bathtub water contaminated with Mycobacterium avium complex (MAC) and hence the name. Although not entirely clear, its etiology has been thought to involve either an infection or a hypersensitivity pneumonitis secondary to MAC. Herein, we describe 2 female patients (60 and 53 years old) admitted to our hospital with hot tub lung, and both of whom worked in a public bath. Both women were initially admitted following several months of exertional dyspnea and cough. The patients had been working as body-scrubbers in a public bath for several years. Their chest CT scans showed bilateral diffuse ground-glass opacities with multifocal air-trappings and poorly defined centrilobular nodules in both lungs. Pathological findings from lung specimens revealed small non-necrotizing granuloma in the lung parenchyme with relatively normal-looking adjacent alveoli. Discontinuation of working in the public bath led to an improvement in symptoms and radiographic abnormalities, without antimycobacterial therapy.