• The Journal of Korean Academic Society of Nursing Education
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• v.11 no.1
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• pp.98-106
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• 2005

The study to identify the relationship among stress associated with clinical experience, coping strategies and self-esteem in nursing students and to provide basic information which is useful for nursing students' learning experience in clinical setting were surveyed using self-reported questionnaires. The findings were summarized : 1. Senior students showed a higher level of stress than junior students. A higher stress level was observed in the unsatisfied group, compared with the neutral group. By class and clinical schedule, students who followed the 3-week class and 3-week clinical schedule showed a higher level of stress than those who followed the 8-week class and 8-week clinical schedule. 2. Senior students had a higher mean coping strategy score than junior students. And the satisfied group showed higher self-esteem, compared with the neutral and unsatisfied group. 3. There was a positive correlation between stress associated with clinical learning experience and coping strategies. But a negative correlation was seen between stress and self-esteem in nursing students. 4. Nursing students used more coping mechanisms as their stress levels increased but showed low self-esteem. The results suggest the need for developing more effective teaching methods and strategies that could improve students' ability to solve problems and sustain their self-esteem even under a stressful circumstance.

• The Korean Journal of Physiology and Pharmacology
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• v.13 no.4
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• pp.315-319
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• 2009

Astragalus Membranaceus (AM) is a useful Korean herb that has been clinically prescribed for stress-related illness. The objective of the present study was to examine the anti-stress effects of AM on repeated stress-induced alterations of anxiety, learning and memory in rats. Restraint stress was administered for 14 days (2h/day) and AM (400mg/kg) given by oral administration, in the AM group, for the same period. Starting on the eighth day, the rats were tested for spatial memory on the Morris water maze test (MW) and for anxiety on the elevated plus maze (EPM). Changes of expression on immunohistochemistry were studied for cholineacetyl transferase (ChAT) and tyrosine hydroxylase (TH) in the brain. The results showed that the rats treated with AM had significantly reduced stress-induced deficits on learning and memory on the spatial memory tasks. In addition, the ChAT immunoreactivities were increased. In the EPM, treatment with AM increased the time spent in the open arms (p<0.001) compared to the control group. In addition, AM treatment also normalized increases of TH expression in the LC (p<0.001). In conclusion, administration of AM improved spatial learning and memory and reduced stress-induced anxiety. Thus, the present results suggest that AM is able to recover behavioral and neurochemical impairments induced by stress.

• Korean Journal of Child Studies
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• v.25 no.4
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• pp.191-200
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• 2004

The purpose of this research is to delineate the effect of maternal variables of the children's depression. Such variables as the mother's age, her education level and maternal parenting stress have been chosen for the analysis. The sample subject were 659 pairs of fifth/sixth grade of elementary school and first/second grade of middle school and their mothers. The data were analyzed frequency, percentage, factor analysis, Cronbach's alpha, ANOVA, Pearson's correlation, and stepwise multiple regression analysis. The major findings of the research are as follows : First, the children's depression is significantly related to mother's education level but the children's depression is not significantly related to mother's age. Second, parenting stress related to temperament, relationship and learning expectation is significantly related to children's depression. Third, the result of step multiple regression analysis on the effects of the maternal variables to the children's depression indicates that maternal parenting stress related to temperament, relationship and mother education level are the significant contributing factor. All in all, the maternal variables account for 7% of the children's depression score.

• Journal of Oriental Neuropsychiatry
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• v.12 no.1
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• pp.123-135
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• 2001

Objective: This study was designed to assess antidepressant effects of Quibitang on an Animal Model of Depression induced by Chronic Mild Stress. Method: The consumption of 1% sucrose solution and active avoidance learning test were used to evaluate antidepressant effect of Quibitang. The consumption of 1% sucrose solution was measured every week for 8 weeks, and active avoidance learning test was executed after 4 weeks treatment of saline or Quibitang. Result: 1. The consumption of 1% sucrose solution was significantly reversed in test group (Quibitang-treated group) at 5th, 7th, 8th weeks, but there was no significant change in control group. 2. Chronic Mild Stress was found to suppress the increase of body weight at 5th, 6th, 7th, 8th weeks. Treatment of Quibitang did not enhanced the body weigt, but it enhanced the consumption of sucrose solution. 3. In order to measure the learning ability of rat which drived to be depressed, we executed active avoidance test. The result revealed that depressed rat showed impaired acquisition than control group, and the treatment of Quibitang restored the learning activity. Conclusion: These results suggest that Quibitang may have antidepressant effects on depression induced by chronic mild stress.

• Child Health Nursing Research
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• v.23 no.1
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• pp.70-80
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• 2017

Purpose: In this study a caregiver's role improvement program was developed and tested to identify the effect on uncertainty, stress, and role performance of caregivers with hospitalized children. Methods: The design of this study was a quasi-experimental study with a nonequivalent control group and a non-synchronized design. Thirty-three caregivers were assigned to the experimental group and 33 to the control group. Data were collected from March 5 2016 to April 10 2016. For the experimental treatment, each individual was given on-site education with situated learning (given 30 minutes each, for 2 sessions), and self-repetition learning activities were performed from the e-book. Data were analyzed using t-test, ${\chi}^2-test$, Fisher's exact test, paired t-test, and independent t-test. Results: The level of uncertainty and stress decreased, and role performance level improved for these caregivers with hospitalized children. Conclusion: The findings of this study show that using on-site education through situated learning and self-repetition learning with an e-book as in the caregiver's role improvement program is an effective intervention. Therefore, utilizing the caregiver role improvement program developed in this study is recommended as an effective intervention for caregivers of hospitalized children.

• Smart Structures and Systems
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• v.29 no.4
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• pp.589-598
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• 2022

Timber structures are susceptible to structural damages caused by variations in moisture content (MC), inducing severe durability deterioration and safety issues. Therefore, it is of great significance to detect MC levels in timber structures. Compared to current methods for timber MC detection, which are time-consuming and require bulky equipment deployment, Lead Zirconate Titanate (PZT)-enabled stress wave sensing combined with statistic machine learning classification proposed in this paper show the advantage of the portable device and ease of operation. First, stress wave signals from different MC cases are excited and received by PZT sensors through active sensing. Subsequently, two non-baseline features are extracted from these stress wave signals. Finally, these features are fed to a statistic machine learning classifier (i.e., naïve Bayesian classification) to achieve MC detection of timber structures. Numerical simulations validate the feasibility of PZT-enabled sensing to perceive MC variations. Tests referring to five MC cases are conducted to verify the effectiveness of the proposed method. Results present high accuracy for timber MC detection, showing a great potential to conduct rapid and long-term monitoring of the MC level of timber structures in future field applications.

• ETRI Journal
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• v.45 no.1
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• pp.105-118
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• 2023

We tested the feasibility of automated discrimination of patients with panic disorder (PD) from healthy controls (HCs) based on multimodal physiological responses using machine learning. Electrocardiogram (ECG), electrodermal activity (EDA), respiration (RESP), and peripheral temperature (PT) of the participants were measured during three experimental phases: rest, stress, and recovery. Eleven physiological features were extracted from each phase and used as input data. Logistic regression (LoR), k-nearest neighbor (KNN), support vector machine (SVM), random forest (RF), and multilayer perceptron (MLP) algorithms were implemented with nested cross-validation. Linear regression analysis showed that ECG and PT features obtained in the stress and recovery phases were significant predictors of PD. We achieved the highest accuracy (75.61%) with MLP using all 33 features. With the exception of MLP, applying the significant predictors led to a higher accuracy than using 24 ECG features. These results suggest that combining multimodal physiological signals measured during various states of autonomic arousal has the potential to differentiate patients with PD from HCs.

• Biomolecules & Therapeutics
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• v.26 no.4
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• pp.368-373
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• 2018

Rapid eye movement (REM) sleep has an essential role in the process of learning and memory in the hippocampus. It has been reported that linalool, a major component of Lavandula angustifolia, has antioxidant, anti-inflammatory, and neuroprotective effects, along with other effects. However, the effect of linalool on the cognitive impairment and behavioral alterations that are induced by REM-sleep deprivation has not yet been elucidated. Several studies have reported that REM-sleep deprivation-induced memory deficits provide a well-known model of behavioral alterations. In the present study, we examined whether linalool elicited an anti-stress effect, reversing the behavioral alterations observed following REM-sleep deprivation in mice. Furthermore, we investigated the underlying mechanism of the effect of linalool. Spatial memory and learning memory were assessed through Y maze and passive avoidance tests, respectively, and the forced swimming test was used to evaluate anti-stress activity. The mechanisms through which linalool improves memory loss and behavioral alterations in sleep-deprived mice appeared to be through an increase in the serotonin levels. Linalool significantly ameliorated the spatial and learning memory deficits, and stress activity observed in sleep-deprived animals. Moreover, linalool led to serotonin release, and cortisol level reduction. Our findings suggest that linalool has beneficial effects on the memory loss and behavioral alterations induced by REM-sleep deprivation through the regulation of serotonin levels.

• The Korean Journal of Physiology and Pharmacology
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• v.14 no.5
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• pp.345-352
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• 2010

The present study was undertaken to explore the potential of erythropoietin in memory deficits of mice. Memory impairment was produced by scopolamine (0.5 mg/kg, $i.p.$) and intracerebroventricular streptozotocin (i.c.v STZ, 3 mg/kg, $10{\mu}l$, $1^{st}$ and $3^{rd}$ day) in separate groups of animals. Morris water-maze test was employed to assess learning and memory. The levels of brain thio-barbituric acid reactive species (TBARS) and reduced glutathione (GSH) were estimated to assess degree of oxidative stress. Brain acetylcholinesterase enzyme (AChE) activity was also measured. Scopolamine/streptozotocin administration induced significant impairment of learning and memory in mice as indicated by marked decrease in Morris water-maze performance. Scopolamine/streptozotocin administration also produced a significant enhancement of brain AChE activity and brain oxidative stress (an increase in TBARS and a decrease in GSH) levels. Treatment of erythropoietin (500 and 1,000 IU/Kg i.p.) significantly reversed scopolamine- as well as streptozotocin-induced learning and memory deficits along with attenuation of those-induced rise in brain AChE activity and brain oxidative stress levels. It may be concluded that erythropoietin exerts a beneficial effect in memory deficits of mice possibly through its multiple actions including potential anti-oxidative effect.

• The Korean Journal of Physiology and Pharmacology
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• v.14 no.6
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• pp.371-376
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• 2010

Glycyrrhizae radix (GR) is an herbal medicine that is commonly used in the East Asia for treating a variety of diseases, including stomach disorders. The objective of the present study was to examine the anti-stress effects of GR on repeated stress-induced alterations of anxiety, learning and memory in rats. Restraint stress was administered for 14 days (2 h/day) to the rats in the Control and GR groups (400 mg/kg/day, PO). Starting on the eighth day, the rats were tested for spatial memory on the Morris water maze test (MW) and for anxiety on the elevated plus maze (EPM). We studied the changes of the expressions of cholineacetyl transferase (ChAT) and tyrosine hydroxylase (TH) in the locus coerleus (LC) using immunohistochemistry. The results showed that the rats treated with GR had significantly reduced stress-induced deficits on their learning and memory on the spatial memory tasks. In addition, the ChAT immunoreactivities were increased. Gor the EPM, treatment with GR increased the time spent in the open arms (p<0.001) as compared to that of the control group. Moreover, GR treatment also normalized the increases of the TH expression in the LC (p<0.001). In conclusion, administration of GR improved spatial learning and memory and reduced stress-induced anxiety. Thus, the present results suggest that GR has the potential to attenuate the behavioral and neurochemical impairments caused by stress.