• International journal of advanced smart convergence
• /
• v.12 no.4
• /
• pp.164-170
• /
• 2023

With the recent advances in AI (artificial intelligence) and HPC (high-performance computing) technologies, deep learning is proliferated in various domains of the 4th industrial revolution. As the workload volume of deep learning increasingly grows, analyzing the memory reference characteristics becomes important. In this article, we analyze the memory reference traces of deep learning workloads in comparison with traditional workloads specially focusing on read and write operations. Based on our analysis, we observe some unique characteristics of deep learning memory references that are quite different from traditional workloads. First, when comparing instruction and data references, instruction reference accounts for a little portion in deep learning workloads. Second, when comparing read and write, write reference accounts for a majority of memory references, which is also different from traditional workloads. Third, although write references are dominant, it exhibits low reference skewness compared to traditional workloads. Specifically, the skew factor of write references is small compared to traditional workloads. We expect that the analysis performed in this article will be helpful in efficiently designing memory management systems for deep learning workloads.

• Korean Journal of Biological Psychiatry
• /
• v.23 no.3
• /
• pp.102-107
• /
• 2016

This review will summarize EEG studies of learning and memory based on frequency bands including theta waves (4-7 Hz), gamma waves (> 30 Hz) and alpha waves (7-12 Hz). Authors searched and reviewed EEG papers especially focusing on learning and memory from PubMed. Theta waves are associated with acquisition of new information from stimuli. Gamma waves are connected with comparing and binding old information in preexisting memory and new information from stimuli. Alpha waves are linked with attention. Eventually it mediates the learning and memory process. Although EEG studies of learning and memory still have controversial issues, the future EEG studies will facilitate clinical benefits by virtue of more developed and encouraging prospects.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.20 no.2
• /
• pp.471-476
• /
• 2006

Chongmyung-tang(CMT, 聰明湯), oriental herbal medicine which consists of Polygaglae Radix(遠志), Acori Graminei Rhizoma(石菖蒲) and Hoelen(白茯神) has effect on amnesia, dementia. In order to evaluate effect of CMT on memory and learning in mice, CMT extract was used for studies. This paper describes the effects of CMT extract on memory and learning processes by using the passive and active avoidance performance tests, novel object recognition task and water maze task. The CMT extract ameliorated the memory retrieval deficit induced by ethanol in the passive avoidance responses but did not affect ambulatory activity of normal mice. These results suggest that CMT has an ameliorating effect on memory retrieval impairment. CMT extract decreased spontaneous motor activity(SMA) in the latter sessions of memory registration in active avoidance responses. These results suggest that CMT has partly transquilizing or antianxiety effects. In novel object recognition task to measure visual recognition memory, CMT-administered mice enhanced in long term memory for 1-3 days. In water maze task to measure spatial learning, which requires the activation of NMDA receptors in the hippocampus, spatial learning in CMT-administered mice was faster than in wild-type mice. These results suggest that CMT enhances memory and activates NMDA receptors.

• 제어로봇시스템학회:학술대회논문집
• /
• 2004.08a
• /
• pp.694-698
• /
• 2004

In this paper, as one of these efforts for making the intelligent data mining system we propose the Associative frame of the memory according to the following three steps. First,the structured frame for performing the main brain function should be made. In this frame, the concepts of learning memory and episode memory are considered. Second,the learning mechanism for data acquisition and storing mechanism in the memory frame are provided. The obtained data are arranged and stored in the memory following the rules of the structured memory frame. Third, it is the last step of processing the inference and knowledge retrieval function using the stored knowledge in the associative memory frame. This system is applied to the area for estimating the purchasing degree from the type of customer's tastes, the pattern of commodities and the evaluation of a company.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.19 no.1
• /
• pp.254-261
• /
• 2005

The effects on memory and learning ability of the Korean herbal medicine, Xingyo-tang(XGT, 神交湯), which consists of Ginseng Radix(人蔘) 4 g, Liriopis Tuber(麥門冬) 40 g, Morindae Officinalis Radix(巴戟天) 40 g, Biotae Semen(柏子仁) 20 g, Dioscoreae Rhizoma(山藥) 40 g, Euryales Semen(?實) 20 g, Scrophulariae Radix(玄蔘) 40 g, Salviae Miltiorrhizae Radix(丹蔘) 12 g, Poria(茯神) 12 g, Cuscutae Semen(免絲子) 40 g, was investigated. The effects of XGT on learning and memory performance were examined in normal or memory impaired mice by using avoidance tests, Pentobarbital -induced sleep test, fear conditioning task, novel object recognition task, and water maze task. Hot water extract from XGT was used for the studies. Learning ability and memory are based on modifications of synaptic strength among neurons that are simultaneously active. Enhanced synaptic coincidence detection leads to better learning and memory. The XGT-treated (30 mg/100 g and 60 mg/100 g, p.o.) mice exhibit superior ability in learning and memorizing when performing various behavioral tasks. XGT did not affect the passive avoidance responses of normal mice in the step through and step down tests, the conditioned and unconditioned avoidance responses of normal mice in the shuttle box, lever press performance tests, and the ambulatory activity of normal mice in normal condition. In contrast, XGT produced ameliorating effects on the memory retrieval impairment induced by ethanol. XGT also improved the memory consolidation disability induced by electric convulsive shock (ECS). XGT extended the sleeping time induced by pentobarbital dose-dependently, suggesting its transquilizing or antianxiety action. These results suggest that XGT has an improving effect on the impaired learning through the effects on memory registration and retrieval.

• Journal of Ginseng Research
• /
• v.20 no.3
• /
• pp.226-232
• /
• 1996

This study was performed to investigate the effect of red ginseng extract including some vitamin B groups as test drug on learning and memory in mice. Single and repeated administrations of the test drug improved the acquisition and the process of consolidation in the tests using step-through and step-down apparatus, indicating this test drug improved learning and memory. However, the test drug did not improve scopolamine-induced amnesia. These results suggest that test drug may be useful as a nootropic agent.

• Sleep Medicine and Psychophysiology
• /
• v.7 no.1
• /
• pp.10-17
• /
• 2000

To investigate the neurobiological bases of learning and memory is one of the ambitious goals of modern neuroscience. The progress in this field of recent years has not only brought us closer to understanding the molecular mechanism underlying long-lasting changes in synaptic strength, but it has also provided further evidence that these mechanisms are required for memory formation. Since twenty years ago, several studies for the tests of the hypothesis that NMDA-dependent hippocampal long-term potentiation(LTP) underlies learning have been reported. Also, in the recent year, data from mutant mice showed that a potential role for NMDA-dependent LTP in hippocampal CA1 and spatial learning. Although the current evidence for the role of NMDA receptor in learning and memory is not still obvious, NMDA receptor seems to act as a critical switch for activation of a cascade of events that underlie synaptic plasticity.

• The Journal of Korean Medicine
• /
• v.20 no.4
• /
• pp.39-49
• /
• 2000

This study was conducted to prove that there exists a relation between the spleen and learning and memory as Oriental medicine believesTo promote the function of the Spleen, Guibitang was administered to rats in this study. Rats were 250～300g Sprague-Dawley, and were divided into three groups. One was the normal group without any pretreatment. Another was the control group which was administered normal saline and the abdominal injection of L-NAME before learning and memory test. And the 3rd was the sample group, to which was administered Guibitang extract and (no 'the') abdominal injection of L-NAME before the learning and memory test. Each group was made up of 12 rats. Morris water maze and radial arm maze tasks were performed in the learning test and Morris water maze task in the memory test. For 2 days to evaluate the ability of learning in the Morris water maze, 16 trials were carried out and first latency(lapse time to find the escape platform for the first time) was measured. The next day, to evaluate the ability of memory, the escape platform was eliminated from the maze, and total path, target entry number, first latency and memory score were measured. 48hrs before the radial arm maze task was performed, bait was deprived from each group. After learning test, bait was permitted to each group. So 85% of the body weight was maintained for 6 days of the test. Each of the eight arms was baited; correct choice numer and error were counted; each trial was finished when the rat had entered each of the eight arms, or more than 10 minutes had elapsed. The results were as follows: In the learning test, the first latency of the sample group in the Morris water maze showed evident improvement of learning compared to control group at the 11th, 12th, 13th trial of 16 trials, and correct choice number in radial arm maze showed noticeable improvement compared to the control group at 3rd, 4th and 5th; In the memory test, the memory score of the sample group showed evident improvement compared to the control group. From the above results, the administration of Guibitang, which tonifies the function of the Spleen, could enhance the ability of learning and memory. So it was suggested that the Spleen has a relation with learning and memory.

• Korean Journal of Cognitive Science
• /
• v.7 no.3
• /
• pp.37-60
• /
• 1996

From the biopsychological point of view,learning could be defined as the processes to transfer the information that we obtain from environment to the neural circuits in the brain.In the studies to determine the biological substrates of learning and memory,there was a remarkable effort to identify neural circuits related with a specific type of learning and to describe the mechanixm of neural plasticity of learning and memory,under the assumption that the memory orinformation may be stored as a modificationof neural synapes in the central nerviys system.On the other hand,there was a different kind of tendency to analyze the mechanism of interactions between neural substrates involved in learning and memory,under the assumption that a specific information may be represented in the patterns of comples neural network of the central nervous system.The present review,in the former position.focused on the research methods and the chracteristics and finding of the investigations employing animal model systems to indentify the essential site of engram for learning and memory.Specifically,the review presents major advances in ourunderstanding of the memory trace circuit for a specific type of learning,with the use of animal model system,the detemination of the critical lodi of neuaral plastic chabges In learing abd memory,and the neurophysiological an biocemical mechanixms of the neural modifia by learint.

• The Journal of Pediatrics of Korean Medicine
• /
• v.15 no.1
• /
• pp.77-104
• /
• 2001

The effects of the oriental herbal medicine Saenghyetang(SHT, 生慧湯), which consists of Rehmanniae Radix (熟地黃 九蒸: was made by 9th steam) 40g, Corni Fructus(山茱黃) 16g, Polygalae Radix(遠志) 8g, Zizyphi Spinosae Semen(酸棗仁) 2g, Biotae Semen(柏子仁 去油: oil ingredient was removed) 20g, Poria Cocos(茯笭) 12g, Ginseng Radix(人蔘) 12g, Acori Graminei Rhizoma(石菖蒲) 2g, Sinapis Semen(白芥子) 8g, on learning ability and memory were investigated. Hot water extract(HWE) and ethanol extract(EE) from SHT were used for the studies. Learning ability and memory are related to modifications of synaptic strength among neurons that interactive. Enhanced synaptic coincidence detection leads to improved learning ability and memory. If the NMDA receptor, a synaptic coincidence detector, acts as a graded switch for memory formations, enhanced signal detection by NMDA receptors should enhance learning ability and memory. It was shown that NR2B was increased in the forebrains of oriental medicine-administrated mice, leading to enhanced activation of NMDA receptors and facilitating synaptic potentiation in response to stimulation at 10-100 Hz. These HWE-SHT treated mice exhibited that superior ability in learning and memory when performing various behavioral tasks, showing that NR2B is enhanced by HWE-SHT treatment and also is critical in gating the age-dependent threshold for plasticity and memory formation. NMDA receptor-dependent modifications, which were mediated in part by HWE administration, of synaptic efficacy, therefore, represent a mechanism for associative learning ability and memory. Results suggest that oriental medical enhancement of NR2B contributes to increase intelligence and memory in mammals On the other hand, to examine the effects of EE-SHT on the learning ability and memory in experimental mice, EE-SHT was tested on passive and active avoidance responses. The EE-SHT ameliorated the memory retrieval deficit induced by ethanol in mice, but not other memory impairments. EE-SHT(10, 20mg/100 g, p.o.) did not affect the passive avoidance responses of normal mice in the step through and step down tests, the conditioned and unconditioned avoidance responses of normal mice in the shuttle box, lever press performance tests and the ambulatory activity of normal mice in a normal condition. However, EE-SHT at 20 mg/kg significantly decrease the spontaneous motor activity during the shuttle box test, and also to extend the sleeping time induced by pentobarbital in mice. These results suggest that SHT has an ameliorating effect on memory retrieval impairments and a weak tranquilizing action.