• Korean Journal of Food Science and Technology
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• v.44 no.4
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• pp.428-433
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• 2012

Probiotics and their products, such as yogurt and cheese have been widely consumed in many countries with proven health benefits including anti-microbial activity and anti-diarrheal activity. LHFM (Lactobacillus helveticus - fermented milk) is a processed skim milk powder, fermented by a probiotics, L. helveticus IDCC3801. In the present study, we aimed to investigate the neuroprotective effects and the cognitive improvements of LHFM. LHFM itself did not show any cytotoxicity to the human neuroblastoma cell line, SH-SY5Y; however, it dose-dependently protected against glutamate-induced neuronal cell death. LHFM also attenuated scopolamine-induced memory deficit in Y-maze and Morris-water maze. In the analysis of hippocampus after a behavior test, LHFM significantly increased the acetylcholine level and also inhibited acetylcholine esterase activity. Therefore, the raised acetylcholine release partially contributes to the improvement of learning and memory by a treatment with LHFM. These results suggest that LHFM is an effective material for prevention or improvement of cognitive impairments caused by neuronal cell damage and central cholinergic dysfunction.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.20 no.1
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• pp.163-169
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• 2020

Recently, research on automation and unmanned operation of machines in the industrial field has been conducted with the advent of AI, Big data, and the IoT, which are the core technologies of the Fourth Industrial Revolution. The machines for these automation processes are controlled based on the data collected from the sensors attached to them, and further, the processes are managed. Conventionally, the abnormalities of sensors are periodically checked and managed. However, due to various environmental factors and situations in the industrial field, there are cases where the inspection due to the failure is not missed or failures are not detected to prevent damage due to sensor failure. In addition, even if a failure occurs, it is not immediately detected, which worsens the process loss. Therefore, in order to prevent damage caused by such a sudden sensor failure, it is necessary to identify the failure of the sensor in an embedded system in real-time and to diagnose the failure and determine the type for a quick response. In this paper, a deep neural network-based fault diagnosis system is designed and implemented using Raspberry Pi to classify typical sensor fault types such as erratic fault, hard-over fault, spike fault, and stuck fault. In order to diagnose sensor failure, the network is constructed using Google's proposed Inverted residual block structure of MobilieNetV2. The proposed scheme reduces memory usage and improves the performance of the conventional CNN technique to classify sensor faults.

• The Journal of the Korea Contents Association
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• v.15 no.4
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• pp.29-44
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• 2015

Digital Signage, a way of advertising or delivering information to viewers through digital displays, has expanded from being just an advertising channel in public places. Recently, it has become widely prevalent in restaurants and retail stores. Despite its wide expansion, digital signage is limited to specific usages and services and the devices it uses are also quite expensive. This study introduces a stick-type digital signage product that operates on Android OS, which addresses all the weaknesses of digital signage with much more reasonable pricing and stable operation. For stability, performance tests were executed on the hardware and applications. The results for hardware performance were extremely promising, as each scenario's maximum performance results, measured by Load Runner programs, reached target indexes. Also, as a result of the usability test, all participants, including non-digital signage system users (novices), were able to easily learn all the tasks. As a result of user satisfaction survey, positive responses were exhibited for ease of learning and usability (LEU), helpfulness and problem solving capabilities (HPSC), affective aspect and multimedia properties (AAMP), commands and minimal memory load (CMML), and control and efficiency (CE).

• Herbal Formula Science
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• v.25 no.4
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• pp.483-497
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• 2017

Background : Behavioral stress has been suggested as one of the significant factors that is able to disrupt physiological systems and cause depression as well as changes in various body systems. The stressful events can alter cognition, learning, memory and emotional responses, resulting in mental disorders such as depression and anxiety. Results : We used a restraint stress model to evaluate the alteration of behavior and stress-related blood parameter. The animals were randomly divided into two groups of five animals each group. Furthermore, we assessed the change of body weight to evaluate the locomotor activity as well as status of emotional and anxiety in mice. After 7 days of restraint stress, the body weight had significantly decreased in the restraint stress group compared with the control group. We also observed stress-associated behavioral alterations, as there was a significant decrease in open field and forced swim test, whereas the immobilization time was significantly increased in the stress group compared to the control group. We observed the morphological changes of neuronal death and microglia by immunohistochemistry and western blot. In our study restraint stress did not cause change in neuronal cell density in the frontal cortex and CA1 hippocampus region, but there was a trend for an increased COX-2 and iNOS protein expression and microglia (CD11b) in brain, which is restraint stress. Conclusion : Our study, there were significant alterations observed in the behavioral studies. We found that mice undergoing restraint stress changed behavior, confirming the increased expression of inflammatory factors in the brain.

• Journal of Applied Biological Chemistry
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• v.64 no.3
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• pp.299-307
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• 2021

Accumulation of amyloid beta (Aβ) and oxidative stress are the most common reason of Alzheimer's disease (AD). In the present study, we investigated the cognitive improvement effects of butanol (BuOH) fraction from Momordica charantia in Aβ_25-35-induced AD mouse model. To develop an AD mouse model, mice were received injection of Aβ_25-35, and then orally administered BuOH fraction from M. charantia at doses of 100 and 200 mg/kg/day during 14 days. In the T-maze and novel object recognition test, administration of BuOH fraction from M. charantia L. at doses of 100 and 200 mg/kg/day improved spatial ability and novel object recognition by increased explorations of novel route and new object. In addition, BuOH fraction of M. charantia-administered groups improved learning and memory abilities by decreased time to reach hidden platform in Morris water maze test. Oral administration of BuOH fraction from M. charantia significantly inhibited lipid peroxidation and nitric oxide levels in the brain, liver, and kidney compared with Aβ_25-35-induced control group. These results indicated that BuOH fraction of M. charantia improved Aβ_25-35-induced cognitive impairment by attenuating oxidative stress. Therefore, M. charantia could be useful for protection from Aβ_25-35-induced cognitive impairment.

• Journal of the Korean Society of Radiology
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• v.13 no.4
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• pp.629-635
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• 2019

In term of the factors affecting psychosocial adjustment of breast cancer patients, their quality of life after surgical operation, radiation, and chemotherapy were systematically meta-analyzed. As a result, their qualities of life of the patients that had radiation therapy was the lowest right after the therapy, and gradually increased after the end of the therapy. However, after six months, their quality of life failed to reach the same level before the therapy. They had depression and side effects the most right after the therapy, and somewhat reduced them after the end of the therapy. In case of surgical operation, the more they were educated, the more they had psychosocial adjustment, and the more they had a medical examination and took out an insurance policy, the more they had psychosocial adjustment. In case of chemotherapy, their cognitive function is influenced so that they have impairments in memory, learning, and thinking stages. Since subjective cognitive impairment has a relationship with depression, it is necessary to monitor depression of chemotherapy patients. Given the results of this systematic meta-analysis, when three types of therapies (surgical operation, radiation therapy, and chemotherapy) are applied to patients with breast cancer, it is necessary to recognize their psychosocial adjustment, depression, anxiety, and quality of life in the nursing and radiation therapy fields and thereby to introduce an intervention program for a holistic approach.

• The Journal of the Korea Contents Association
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• v.14 no.10
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• pp.416-428
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• 2014

This study aimed to identify middle school students' perceptions and practices of handwriting, and factors affecting their attitudes towards handwriting. Data were collected by means of a survey targeting 346 students enrolled in 9 middle schools(Male=172, Female=172, Unknown=2, M=13.5 years old, SD= .94). Interviews, too, were conducted with 12 students in order to identify the students' perceptions of handwriting. The analyses of both survey and interview data revealed the following: (1) the majority of the interviewee students believed that handwriting is useful for memory and summarization so as to get a better school grade, including performance evaluations; (2) Many of the interviewee students were unsatisfied with their handwriting skills, giving higher scores to their peers' handwriting; (3) 45.7% of the students reported that mother was the one who taught them how to write for the first time; and 49.7% of them had no learning experience of taking notes; (4) Girls than boys and 1st graders than 2 or 3 graders showed more positive attitude towards handwriting; and (5) A multiple regression analysis showed that all the variables entered in the regression model, including sex, grade, affective attitude toward hands-on activities, physical abilities, time spent using a computer, and perceptions of Korean characters, had significant impacts on the students' attitudes towards handwriting.

• Journal of Korea Water Resources Association
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• v.31 no.1
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• pp.13-25
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• 1998

It is necessary to develop methodologies for the application of artificial neural network into hydrologic rainfall-runoff process, although there is so much applicability by using the functions of associative memory based on recognition for the relationships between causes and effects and the excellent fitting capacity for the nonlinear phenomenon. In this study, some problems are presented in the application procedures of artificial neural networks and the simulation of runoff hydrograph experiences are reviewed with nonlinear functional approximator by artificial neural network for rainfall-runoff relationships in a watershed. which is regarded as hydrdologic black box model. The neural network models are constructed by organizing input and output patterns with the deserved rainfall and runoff data in Pyoungchang river basin under the assumption that the rainfall data is the input pattern and runoff hydrograph is the output patterns. Analyzed with the results. it is possible to simulate the runoff hydrograph with processing element of artificial neural network with any hydrologic concepts and the weight among processing elements are well-adapted as model parameters with the assumed model structure during learning process. Based upon these results. it is expected that neural network theory can be utilized as an efficient approach to simulate runoff hydrograph and identify the relationship between rainfall and runoff as hydrosystems which is necessary to develop and manage water resources.

• Journal of the Korea Convergence Society
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• v.10 no.3
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• pp.373-382
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• 2019

This study was performed to investigate the effects of creative teaching technique(CTT) on critical thinking disposition(CTD), problem solving process(PSP), and self-leadership(SL) in 5 majors of first to third grades in a college nursing department. CTT was developed to promote memory and practical ability. The study was conducted from August 1 to December 31 in 2017, and the survey was performed before and after applying the CTT. As a result, there was no difference in CTD, PSP, and SL in the first graders whom applied various teaching techniques to one subject. But CTD was 6.8point(p<0.001), PSP was 7.5~7.9point(p<0.001) and SL was 2.9~3.3point(p<0.001) improved in the second and third grades whom applied similar teaching techniques in two subjects. In order to improve the students' core competency, it is more effective for students to apply one or two methods repeatedly in several subjects than to apply various methods to one subject. Since the CTT was more effective in the group that selected the major depending on aptitude and interest, it is necessary to develop various teaching and learning strategies to enhance the interest in nursing major.

• Journal of Korea Entertainment Industry Association
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• v.15 no.5
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• pp.141-151
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• 2021

This study analyzed the meaning and functions of '-(으)ㄹ 것 같다' and '-나 보다' among the various semantic functions depending on the situation, and discussed ways to train speculative expressions more efficiently by expanding them from traditional teaching methods through visualizations applied visual thinking at real Korean language education. The speculative representation, which is the subject of this study, represents the speaker's speculation about something or situation, with slight differences in meaning depending on the basis of the speculation and the subject of the speculation. We propose a training method that can enhance the diversification and efficiency of teaching-learning through visualization of information or knowledge, speculative representations that exhibit fine semantic differences in various situations. Utilizing visual thinking in language education can simplify and provide language information through visualization of language knowledge, and learners can be efficient at organizing and organizing language knowledge. It also has the advantage of long-term memory of language information through visualization of language knowledge. Attempts of various educational methods that can be applied at the Korean language education site can contribute to establishing a more systematic and efficient education method, which is meaningful in that the visual thinking proposed in this study can give interest and efficiency to international students.