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LymphanaxTM Enhances Lymphangiogenesis in an Artificial Human Skin Model, Skin-lymph-on-a-chip (스킨-림프-칩 상에서 LymphanaxTM 의 림프 형성 촉진능)

  • Phil June Park;Minseop Kim;Sieun Choi;Hyun Soo Kim;Seok Chung
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.50 no.2
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    • pp.119-129
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    • 2024
  • The cutaneous lymphatic system in humans plays a crucial role in draining interstitial fluid and activating the immune system. Environmental factors, such as ultraviolet light and natural aging, often affect structural changes of such lymphatic vessels, causing skin dysfunction. However, some limitations still exist because of no alternatives to animal testing. To better understand the skin lymphatic system, a biomimetic microfluidic platform, skin-lymph-on-a-chip, was fabricated to develop a novel in vitro skin lymphatic model of humans and to investigate the molecular and physiological changes involved in lymphangiogenesis, the formation of lymphatic vessels. Briefly, the platform involved co-culturing differentiated primary normal human epidermal keratinocytes (NHEKs) and dermal lymphatic endothelial cells (HDLECs) in vitro. Based on our system, LymphanaxTM, which is a condensed Panax ginseng root extract obtained through thermal conversion for 21 days, was applied to evaluate the lymphangiogenic effect, and the changes in molecular factors were analyzed using a deep-learning-based algorithm. LymphanaxTM promoted healthy lymphangiogenesis in skin-lymphon-a-chip and indirectly affected HDELCs as its components rarely penetrated differentiated NHEKs in the chip. Overall, this study provides a new perspective on LymphanaxTM and its effects using an innovative in vitro system.

Detecting high-resolution usage status of individual parcel of land using object detecting deep learning technique (객체 탐지 딥러닝 기법을 활용한 필지별 조사 방안 연구)

  • Jeon, Jeong-Bae
    • Journal of Cadastre & Land InformatiX
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    • v.54 no.1
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    • pp.19-32
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    • 2024
  • This study examined the feasibility of image-based surveys by detecting objects in facilities and agricultural land using the YOLO algorithm based on drone images and comparing them with the land category by law. As a result of detecting objects through the YOLO algorithm, buildings showed a performance of detecting objects corresponding to 96.3% of the buildings provided in the existing digital map. In addition, the YOLO algorithm developed in this study detected 136 additional buildings that were not located in the digital map. Plastic greenhouses detected a total of 297 objects, but the detection rate was low for some plastic greenhouses for fruit trees. Also, agricultural land had the lowest detection rate. This result is because agricultural land has a larger area and irregular shape than buildings, so the accuracy is lower than buildings due to the inconsistency of training data. Therefore, segmentation detection, rather than box-shaped detection, is likely to be more effective for agricultural fields. Comparing the detected objects with the land category by law, it was analyzed that some buildings exist in agricultural and forest areas where it is difficult to locate buildings. It seems that it is necessary to link with administrative information to understand that these buildings are used illegally. Therefore, at the current level, it is possible to objectively determine the existence of buildings in fields where it is difficult to locate buildings.

Multi-View 3D Human Pose Estimation Based on Transformer (트랜스포머 기반의 다중 시점 3차원 인체자세추정)

  • Seoung Wook Choi;Jin Young Lee;Gye Young Kim
    • Smart Media Journal
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    • v.12 no.11
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    • pp.48-56
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    • 2023
  • The technology of Three-dimensional human posture estimation is used in sports, motion recognition, and special effects of video media. Among various methods for this, multi-view 3D human pose estimation is essential for precise estimation even in complex real-world environments. But Existing models for multi-view 3D human posture estimation have the disadvantage of high order of time complexity as they use 3D feature maps. This paper proposes a method to extend an existing monocular viewpoint multi-frame model based on Transformer with lower time complexity to 3D human posture estimation for multi-viewpoints. To expand to multi-viewpoints our proposed method first generates an 8-dimensional joint coordinate that connects 2-dimensional joint coordinates for 17 joints at 4-vieiwpoints acquired using the 2-dimensional human posture detector, CPN(Cascaded Pyramid Network). This paper then converts them into 17×32 data with patch embedding, and enters the data into a transformer model, finally. Consequently, the MLP(Multi-Layer Perceptron) block that outputs the 3D-human posture simultaneously updates the 3D human posture estimation for 4-viewpoints at every iteration. Compared to Zheng[5]'s method the number of model parameters of the proposed method was 48.9%, MPJPE(Mean Per Joint Position Error) was reduced by 20.6 mm (43.8%) and the average learning time per epoch was more than 20 times faster.

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Understanding Privacy Infringement Experiences in Courier Services and its Influence on User Psychology and Protective Action From Attitude Theory Perspective (택배 서비스 이용자의 프라이버시 침해 경험이 심리와 행동에 미치는 영향에 대한 이해: 태도이론 측면)

  • Se Hun Lim;Dan J. Kim;Hyeonmi Yoo
    • Information Systems Review
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    • v.25 no.3
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    • pp.99-120
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    • 2023
  • Courier services users' experience of violating privacy affects psychology and behavior of protecting personal privacy. Depending on what privacy infringement experience (PIE) of courier services users, learning about perceived privacy infringement incidents is made, recognition is formed, affection is formed, and behavior is appeared. This paradigm of changing in privacy psychologies of courier services users has an important impact on predicting responses of privacy protective action (PPA). In this study, a theoretical research framework are developed to explain the privacy protective action (PPA) of courier services users by applying attitude theory. Based on this framework, the relationships among past privacy infringement experience (PIE), perceived privacy risk (PPR), privacy concerns (i.e., concerns in unlicensed secondary use (CIUSU), concerns in information error (CIE), concerns in improper access (CIA), and concern in information collection (CIC), and privacy protective action (PPA) are analyzed. In this study, the proposed research model was surveyed by people with experience in using courier services and was analyzed for finding relationships among research variables using structured an equation modeling software, SMART-PLS. The empirical results show the causal relationships among PIE, PPR, privacy concerns (CIUSU, CIE, CIA, and CIC), and PPA. The results of this study provide useful theoretical implications for privacy management research in courier services, and practical implications for the development of courier services business model.

Financial Products Recommendation System Using Customer Behavior Information (고객의 투자상품 선호도를 활용한 금융상품 추천시스템 개발)

  • Hyojoong Kim;SeongBeom Kim;Hee-Woong Kim
    • Information Systems Review
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    • v.25 no.1
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    • pp.111-128
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    • 2023
  • With the development of artificial intelligence technology, interest in data-based product preference estimation and personalized recommender systems is increasing. However, if the recommendation is not suitable, there is a risk that it may reduce the purchase intention of the customer and even extend to a huge financial loss due to the characteristics of the financial product. Therefore, developing a recommender system that comprehensively reflects customer characteristics and product preferences is very important for business performance creation and response to compliance issues. In the case of financial products, product preference is clearly divided according to individual investment propensity and risk aversion, so it is necessary to provide customized recommendation service by utilizing accumulated customer data. In addition to using these customer behavioral characteristics and transaction history data, we intend to solve the cold-start problem of the recommender system, including customer demographic information, asset information, and stock holding information. Therefore, this study found that the model proposed deep learning-based collaborative filtering by deriving customer latent preferences through characteristic information such as customer investment propensity, transaction history, and financial product information based on customer transaction log records was the best. Based on the customer's financial investment mechanism, this study is meaningful in developing a service that recommends a high-priority group by establishing a recommendation model that derives expected preferences for untraded financial products through financial product transaction data.

Field Perception Analysis on Policy Outcomes of Academic Libraries (국내 대학도서관 정책 성과에 대한 현장 인식 조사)

  • Jongwook Lee;Woojin Kang;Youngmi Jung
    • Journal of Korean Library and Information Science Society
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    • v.54 no.4
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    • pp.415-436
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    • 2023
  • In this study, we aimed to examine the level of implementation of the second comprehensive plan for promoting academic libraries (2019-2023) by analyzing key statistics of academic libraries and gathering perceptions from library staff. We analyzed the changes in major statistical indicators of libraries over the past five years. Additionally, we surveyed library staff to understand their overall perceptions of the plan and their attitudes towards the 17 sub-tasks outlined in it. The analysis of 369 survey responses revealed several key findings. Firstly, most respondents comprehended the plan well and frequently utilized it for developing their libraries' development and implementation plans. Secondly, the IPA results indicated that regardless of the type of university, there should be a continuous focus on facility improvement, teaching-learning support, and expanding access to academic resources. Efforts to develop library policies and strengthen human and financial resources were identified as crucial. Thirdly, four-year universities particularly emphasized the importance of expanding access to international academic resources compared to junior colleges. Conversely, junior colleges perceived foundational skill-building programs and inclusive services as more significant than four-year universities. The application of the IPA diagonal model revealed that the performance levels of all sub-tasks were lower than their perceived importance levels, suggesting the need for strategies to enhance effectiveness in future comprehensive plan formulation.

A Study on Biometric Model for Information Security (정보보안을 위한 생체 인식 모델에 관한 연구)

  • Jun-Yeong Kim;Se-Hoon Jung;Chun-Bo Sim
    • The Journal of the Korea institute of electronic communication sciences
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    • v.19 no.1
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    • pp.317-326
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    • 2024
  • Biometric recognition is a technology that determines whether a person is identified by extracting information on a person's biometric and behavioral characteristics with a specific device. Cyber threats such as forgery, duplication, and hacking of biometric characteristics are increasing in the field of biometrics. In response, the security system is strengthened and complex, and it is becoming difficult for individuals to use. To this end, multiple biometric models are being studied. Existing studies have suggested feature fusion methods, but comparisons between feature fusion methods are insufficient. Therefore, in this paper, we compared and evaluated the fusion method of multiple biometric models using fingerprint, face, and iris images. VGG-16, ResNet-50, EfficientNet-B1, EfficientNet-B4, EfficientNet-B7, and Inception-v3 were used for feature extraction, and the fusion methods of 'Sensor-Level', 'Feature-Level', 'Score-Level', and 'Rank-Level' were compared and evaluated for feature fusion. As a result of the comparative evaluation, the EfficientNet-B7 model showed 98.51% accuracy and high stability in the 'Feature-Level' fusion method. However, because the EfficietnNet-B7 model is large in size, model lightweight studies are needed for biocharacteristic fusion.

Automatic scoring of mathematics descriptive assessment using random forest algorithm (랜덤 포레스트 알고리즘을 활용한 수학 서술형 자동 채점)

  • Inyong Choi;Hwa Kyung Kim;In Woo Chung;Min Ho Song
    • The Mathematical Education
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    • v.63 no.2
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    • pp.165-186
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    • 2024
  • Despite the growing attention on artificial intelligence-based automated scoring technology as a support method for the introduction of descriptive items in school environments and large-scale assessments, there is a noticeable lack of foundational research in mathematics compared to other subjects. This study developed an automated scoring model for two descriptive items in first-year middle school mathematics using the Random Forest algorithm, evaluated its performance, and explored ways to enhance this performance. The accuracy of the final models for the two items was found to be between 0.95 to 1.00 and 0.73 to 0.89, respectively, which is relatively high compared to automated scoring models in other subjects. We discovered that the strategic selection of the number of evaluation categories, taking into account the amount of data, is crucial for the effective development and performance of automated scoring models. Additionally, text preprocessing by mathematics education experts proved effective in improving both the performance and interpretability of the automated scoring model. Selecting a vectorization method that matches the characteristics of the items and data was identified as one way to enhance model performance. Furthermore, we confirmed that oversampling is a useful method to supplement performance in situations where practical limitations hinder balanced data collection. To enhance educational utility, further research is needed on how to utilize feature importance derived from the Random Forest-based automated scoring model to generate useful information for teaching and learning, such as feedback. This study is significant as foundational research in the field of mathematics descriptive automatic scoring, and there is a need for various subsequent studies through close collaboration between AI experts and math education experts.

Survey of the Knowledge of Korean Radiology Residents on Medical Artificial Intelligence (의료 인공지능에 대한 대한민국 영상의학과 전공의의 인식 조사 연구)

  • Hyeonbin Lee;Seong Ho Park;Cherry Kim;Seungkwan Kim;Jaehyung Cha
    • Journal of the Korean Society of Radiology
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    • v.81 no.6
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    • pp.1397-1411
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    • 2020
  • Purpose To survey the perception, knowledge, wishes, and expectations of Korean radiology residents regarding artificial intelligence (AI) in radiology. Materials and Methods From June 4th to 7th, 2019, questionnaires comprising 19 questions related to AI were distributed to 113 radiology residents. Results were analyzed based on factors such as the year of residency and location and number of beds of the hospital. Results A total of 101 (89.4%) residents filled out the questionnaire. Fifty (49.5%) respondents had studied AI harder than the average while 68 (67.3%) had a similar or higher understanding of AI than the average. In addition, the self-evaluation and knowledge level of AI were significantly higher for radiology residents at hospitals located in Seoul and Gyeonggi-do compared to radiology residents at hospitals located in other regions. Furthermore, the self-evaluation and knowledge level of AI were significantly lower in junior residents than in residents in the 4th year of training. Of the 101 respondents, only 16 (15.8%) had experiences in AI-related study while 91 (90%) were willing to participate in AI-related study in the future. Conclusion Organizational efforts through a radiology society would be needed to meet the need of radiology trainees for AI education and to promote the role of radiologists more adequately in the era of medical AI.

Conventional Versus Artificial Intelligence-Assisted Interpretation of Chest Radiographs in Patients With Acute Respiratory Symptoms in Emergency Department: A Pragmatic Randomized Clinical Trial

  • Eui Jin Hwang;Jin Mo Goo;Ju Gang Nam;Chang Min Park;Ki Jeong Hong;Ki Hong Kim
    • Korean Journal of Radiology
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    • v.24 no.3
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    • pp.259-270
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    • 2023
  • Objective: It is unknown whether artificial intelligence-based computer-aided detection (AI-CAD) can enhance the accuracy of chest radiograph (CR) interpretation in real-world clinical practice. We aimed to compare the accuracy of CR interpretation assisted by AI-CAD to that of conventional interpretation in patients who presented to the emergency department (ED) with acute respiratory symptoms using a pragmatic randomized controlled trial. Materials and Methods: Patients who underwent CRs for acute respiratory symptoms at the ED of a tertiary referral institution were randomly assigned to intervention group (with assistance from an AI-CAD for CR interpretation) or control group (without AI assistance). Using a commercial AI-CAD system (Lunit INSIGHT CXR, version 2.0.2.0; Lunit Inc.). Other clinical practices were consistent with standard procedures. Sensitivity and false-positive rates of CR interpretation by duty trainee radiologists for identifying acute thoracic diseases were the primary and secondary outcomes, respectively. The reference standards for acute thoracic disease were established based on a review of the patient's medical record at least 30 days after the ED visit. Results: We randomly assigned 3576 participants to either the intervention group (1761 participants; mean age ± standard deviation, 65 ± 17 years; 978 males; acute thoracic disease in 472 participants) or the control group (1815 participants; 64 ± 17 years; 988 males; acute thoracic disease in 491 participants). The sensitivity (67.2% [317/472] in the intervention group vs. 66.0% [324/491] in the control group; odds ratio, 1.02 [95% confidence interval, 0.70-1.49]; P = 0.917) and false-positive rate (19.3% [249/1289] vs. 18.5% [245/1324]; odds ratio, 1.00 [95% confidence interval, 0.79-1.26]; P = 0.985) of CR interpretation by duty radiologists were not associated with the use of AI-CAD. Conclusion: AI-CAD did not improve the sensitivity and false-positive rate of CR interpretation for diagnosing acute thoracic disease in patients with acute respiratory symptoms who presented to the ED.