• Title/Summary/Keyword: Leaflet

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Parametric Analysis on the Viral Infection in The Rat Circardian Control Center (흰쥐의 일주기조절중추내 바이러스 감염에 대한 매개변수 분석)

  • Kim Jin-Sang
    • The Journal of Korean Physical Therapy
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    • v.10 no.2
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    • pp.113-125
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    • 1998
  • The neurotropic psudorabies virus(PRV) to replicate within neurons is very useful pathogen for neuronal tracing. I carried out this study to investigate the parametric analysis on the viral infection in the rat circadian control center with two genetically engineered strains out of PRV. The two strains are isogenic with the attenuated Bartha strain of PRV ; in one strain a lacZ reporter gene was inserted into the gC locus (PRV-BaBlu ; $4.75\times10^8pfu/ml$) and the other strain contained a PRV envelope glycoprotein gene(PRV-D ; $2.5\times10^8pfu/ml$) theat is absent in PRV-BaBlu. simultaneous or temporally separated sequential injection of$2{\mu}l$ of each strain into the vetreous body of eye produced a course of transsynaptic infection of retinohypothalamic circuitry. The results were as follows; 1. PRV-BaBlu and PRV-D infected the suprachiasmatic nucleus in hypothalamus and intergeniculate leaflet in lateral geniculate nucleus of thalamus. 2. The rate of PRV infection was dependent upon PRV strain. 3. Pre-infected neurons by PRV-D were interfered with the replication of PRV-BaBlu. 4. Dual injection of PRV-D and PRV-BaBlu showed more virulent than the parental strain.

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Aortic Valve Papillary Fibroelastoma Triggering Chest Pain -A case report- (흉통을 유발한 대동맥판막의 유두상 섬유탄력종 -1예 보고-)

  • Yeo, In-Gwon;Jung, Yo-Chun;Cho, Kwang-Ree;Kim, Ki-Bong
    • Journal of Chest Surgery
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    • v.39 no.11 s.268
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    • pp.858-860
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    • 2006
  • Papillary fibroelastoma is the second most common benign cardiac tumor, usually involving the cardiac valve. Papillary fibroelastoma attached at the right coronary cusp of the aortic valve was found in a 51-year-old woman, who was presented with chest pain and dyspnea. During the operation, the tumor mass was excised without causing damage on the aortic valve leaflet.

Dynamics of C60 Molecules in Biological Membranes: Computer Simulation Studies

  • Chang, Rak-Woo;Lee, Ju-Min
    • Bulletin of the Korean Chemical Society
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    • v.31 no.11
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    • pp.3195-3200
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    • 2010
  • We have performed molecular dynamics simulations of atomistic models of $C_{60}$ molecules and DMPC bilayer membranes to study the static and dynamic effects of carbon nanoparticles on biological membranes. All four $C_{60}$-membrane systems were investigated representing dilute and concentrated solutions of $C_{60}$ residing either inside or outside the membrane. The concentrated $C_{60}$ molecules in water phase start forming an aggregated cluster. Due to its heavy mass, the cluster tends to adhere on the surface of the bilayer membrane, hindering both translational and rotational diffusion of individual $C_{60}$. On the other hand, once $C_{60}$ molecules accumulate inside the membrane, they are well dispersed in the central region of the bilayer membrane. Because of the homogeneous dispersion of $C_{60}$ inside the membrane, each leaflet is pushed away from the center, making the bilayer membrane thicker. This thickening of the membrane provides more room for both translational and rotational motions of $C_{60}$ inside the membrane compared to that in the water region. As a result, the dynamics of $C_{60}$ inside the membrane becomes faster with increasing its concentration.

Effects of Provision of Concrete Information about Patient-controlled Analgesia in Hysterectomy Patients (자궁 적출 수술 환자를 대상으로 한 통증 자가 조절기 관련 구체적 정보 제공의 효과)

  • Lee, Bo Gyeong;Lee, Young Whee
    • Women's Health Nursing
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    • v.20 no.3
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    • pp.204-214
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    • 2014
  • Purpose: This study was to investigate the effects of the provision of concrete information about patient-controlled analgesia (PCA) in hysterectomy patients. Methods: Study design was a nonequivalent control group non-synchronized pre- and post-test design. Sixty subjects participated were assigned to experimental group (30 patients) or control group (30 patients) at one university hospital. Concrete information about PCA was composed of three sections: explanation with a leaflet, practice of using PCA, and question and answer session. Results: The experimental group who received concrete information about PCA before surgery had statistically higher knowledge level about PCA, more positive attitude toward pain control analgesia, a lower pain score, and a higher satisfaction level of the use of PCA post-surgery compared to the control group who received general information before surgery. Conclusion: Provision of concrete information about PCA was an effective nursing intervention that reduced post-operative pain for patients and increased their satisfaction with using PCA. It is recommended that concrete information about PCA be provided by nurses to promote the use of PCA and consequently reduce patient's pain post-surgery.

Taxonomic reconsideration of Chinese Lespedeza maximowiczii (Fabaceae) based on morphological and genetic features, and recommendation as the independent species L. pseudomaximowiczii

  • JIN, Dong-Pil;XU, Bo;CHOI, Byoung-Hee
    • Korean Journal of Plant Taxonomy
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    • v.48 no.3
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    • pp.153-162
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    • 2018
  • Lespedeza maximowiczii C. K. Schneid. (Fabaceae) is a deciduous shrub which is known to be distributed in the temperate forests of China, Korea and on Tsushima Island of Japan. Due to severe morphological variations within species, numerous examinations have been conducted for Korean L. maximowiczii. However, the morphology of Chinese plants has not been studied as thoroughly, despite doubts about their taxonomy. To clarify this taxonomic issue, we investigated morphological characters and undertook a Bayesian clustering analysis with microsatellite markers. The morphological and genetic traits of Chinese individuals varied considerably from those of typical L. maximowiczii growing in Korea. For example, petals of the former had a different shape and bore long claws, while the calyx lobes were diverged above the middle and the upper surface of the leaflet was pubescent. Their terete buds and spirally arranged bud scales were distinct from those within the series/section Heterolespedeza, which includes L. maximowiczii. Our Bayesian clustering analysis additionally included L. buergeri as an outgroup. Those results indicated that the Chinese samples clustered into a lineage separated from L. maximowiczii (optimum cluster, K = 2), despite the fact that the latter is grouped into the same lineage with L. buergeri. Therefore, we treat those Chinese plants as a new species with the name L. pseudomaximowiczii.

Echocardiographic Diagnosis of Subaortic Stenosis with Severe Deformation of Mitral Valve Apparatus in a Dog

  • Chung, Doo-ri;Yoon, Young-min;Hwang, Tae-sung;Choi, Moon-yeong;Jung, Dong-in;Yeon, Seong-chan;Lee, Hee-chun
    • Journal of Veterinary Clinics
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    • v.34 no.1
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    • pp.54-57
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    • 2017
  • A 1-year-old castrated male Schnauzer dog was presented with heart murmur. Auscultation revealed systolic murmur located at the left heart base (grade 5/6). There were no remarkable findings on thoracic radiographs. Two-dimensional echocardiography revealed subaortic tunnel-like obstruction at the entrance to the left ventricular outflow tract. Anterior mitral valve leaflet appeared to be tethered to septum with minimal motion. Chordae tendineae was abnormally thickened. Color Doppler analysis revealed turbulent flow starting below the aortic valve. Mitral regurgitation was presented during systole. Spectral Doppler recordings revealed high velocity flow through the aorta and mitral regurgitation. Based on echocardiographic examination, the dog was diagnosed with subaortic stenosis concurrent with mitral dysplasia. The patient was medicated with ${\beta}-blocker$ and diuretics. It has been doing well without apparent clinical signs at 2 year after the diagnosis.

Left Ventricular Outflow Tract Obstruction Caused by Accessory Mitral Valve Tissue in a Child -A case report- (소아에서 부승모판막(Accessoy Mitral Valve Tissue)에 의한 좌심실 유출로 협착 - 1예 보고 -)

  • Lee, Chung-Eun;Lee, Sang-Ho;Choi, Jun-Young;Yang, Jun-Ho
    • Journal of Chest Surgery
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    • v.41 no.3
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    • pp.363-365
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    • 2008
  • Accessory mitral valve tissue is a very rare congenital cardiac malformation and it is an uncommon cause of left Ventricular outflow tract obstruction(LVOTO). The pathogenetic mechanism of subaortic obstruction is thought to be systolic ballooning of the abnormal valve tissue into LVOT. We are reporting a case of an accessory mitral valve tissue that was associated with LVOTO, and this was completely relieved after trans-aortic surgical excision of the accessory tissue.

Taxonomic position and genetic differentiation of Korean Astragalus mongholicus Bunge (한국산 황기의 분류학적 위치 및 유전적 분화)

  • Choi, In-Su;Kim, So-Young;Choi, Byoung-Hee
    • Korean Journal of Plant Taxonomy
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    • v.43 no.1
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    • pp.12-21
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    • 2013
  • To clarify the taxonomic position for Astragalus nakaianus and provide correct scientific name for A. mongholicus cultivar in South Korea, we examined external morphological characters and sequence variations from ITS and five cp non-coding DNA regions. Genetic structure was also analyzed for 61 individuals from three populations using nine microsatellite loci. We found no significant difference between the South Korean cultivar and A. mongholicus var. dahuricus when morphology and ITS sequences were considered. Morphologically, A. nakaianus specimens varied somewhat from A. mongholicus var. mongholicus and var. dahuricus in habit, plant height, and lengths of leaf axis and leaflet. Although sequence data from ITS and cp noncoding DNA regions could not distinguished A. nakaianus from A. mongholicus, microsatellite analysis revealed strong structuring between the cultivar and A. nakaianus. Therefore, we conclude that the South Korean A. mongholicus cultivar should be treated as A. mongholicus var. dahuricus and that A. nakaianus should be merged into A. mongholicus as a variety, i.e., A. mongholicus var. nakaianus.

Phylogenetic study of East-Asia Astragalus L. based on morphological characters (형태형질에 기초한 동아시아산 황기속 식물의 계통분류)

  • Song, Il-Bae;Heo, Kweon
    • Korean Journal of Plant Taxonomy
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    • v.44 no.3
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    • pp.191-201
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    • 2014
  • In order to find useful taxonomic morphological characters, 17 taxa from East-Asia Astragalus and Oxytropis anertii were investigated. In this study, seed coat structure, fruit surface, and fruit anatomical structures were selected to classify the species in Astragalus. As a results, useful morphological and anatomical characters in East-Asia Astragalus were life cycle, leaflet shape, raceme, petal color, seed color, pod shape, absent or present of hairs in pod surface, bent degree of dorsal suture, and thickness of endocarp. Using medicinal sources in China, A. floridus, A. membranaceus, A. membranaceus var. mongholicus and A. tongolensis were formed same group. However, these were not completely consensus in the morphological characters. The other hand, A. koraiensis and A. sikokianus, which have controversial taxonomic issue, have clearly no differences morphological characters each other. Therefore, A. koraiensis, A. sikokianus, and A. bhotanensis should be conducted a comparative study on the DNA sequences and molecular cytology in order to clarify the taxonomic treatments in the near future.

Early surgical intervention for unusually located cardiac fibroelastomas

  • Chung, Eui Suk;Lee, Jae Hoon;Seo, Jong Kwon;Kim, Byung Gyu;Kim, Gwang Sil;Lee, Hye Young;Byun, Young Sup;Kim, Hyun Jung
    • Journal of Yeungnam Medical Science
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    • v.37 no.4
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    • pp.345-348
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    • 2020
  • Papillary fibroelastomas are the second most common primary cardiac tumor in adults. Over 80% of fibroelastomas occur on the cardiac valves, usually on the left side of the heart, while the remaining lesions are typically scattered throughout the atria and ventricles. Although the optimal timing for surgery is controversial and depends on tumor size and location, prompt surgical resection is warranted in patients at high risk of embolism. A tumor on the cardiac valve can be removed using the slicing excision technique without leaflet injury. Here we present two cases of papillary fibroelastomas occurring on the ventricular surface of the aortic valve and in the right ventricle.