• Nuclear Medicine and Molecular Imaging
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• 제42권sup1호
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• pp.116-120
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• 2008

Prostate cancer is the second leading cause of cancer death of men in western countries and the death related to this disease in Korea is also getting increased. Although anatomic imaging tools such as transrectal US or MRI have been playing a great role in detection of primary prostate lesion, the evaluation of regional lymph node or distant organ metastasis using these modalities is not successful. $^{18}F-FDG-PET$ scan is emerging diagnostic tool for various malignancies. Considering the usual characteristics of prostate cancer such as slow growing and osteoblastic metastasis, the application of FDG PET scan to this disease might be limited. However, in advanced prostate cancer refractory to chemotherapy, FDG PET scan show strong FDG uptake and SUV changes in serial PET scan can be a good indicator of treatment response. Although FDG PET can be useful only in limited cases of prostate cancer, its indication can be widened in future owing to rapid technical improvement and accumulated experiences in this field.

• Journal of Information Science Theory and Practice
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• 제1권4호
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• pp.12-37
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• 2013

Organizational climate and organization culture can be some of the leading factors in hindering knowledge sharing within the organization. It is generally accepted that successful knowledge management practice, including knowledge sharing, comes as a result of a conducive and knowledge sharing friendly environment. Organizations that promote and reward collective work generate a trustful and a more collaborative learning culture. The perception of fairness in an organization has been considered an important indicator of employee behavior, attitude, and motivation. This study investigates organizational justice perception and its impact on knowledge sharing practices among forensic experts in the Turkish National Police. The study findings revealed that senior officers, who are experts in the field, have the strongest organizational justice perception. Meanwhile, noncommissioned officers or technicians bear positive but comparatively weaker feelings about the existence of justice within the organization. The study argues that those who satisfy their career expectations tend to have a higher organizational justice perception.

• 한국정보시스템학회지:정보시스템연구
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• 제29권1호
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• pp.289-301
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• 2020

Purpose This study analyzes whether Internet search of cryptocurrency has a causal relationship to return and volatility of cryptocurrency. Design/methodology/approach Google Trend was used as a measure of the level of Internet search, and the parametric tests of Granger causality in the 1st moment and the 2nd moment were adopted as the analysis method. We used Bitcoin's dollar-based price, which is the No. 1 market value among cryptocurrency. Findings The results showed that the Internet search measured by Google Trends has a causal relationship to cryptocurrency in both average and volatility, while there is a difference in causality and its degree according to the search area and category that Google Trend user should set. Because the Granger causality is based on the improvement of prediction, the analysis results of this study indicate that Internet search can be used as a leading indicator in predicting return and volatility of cryptocurrency.

• East Asian Economic Review
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• 제23권2호
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• pp.203-223
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• 2019

This paper examines the interactions between financial conditions and business cycles in Mongolia, a small open economy, heavily depending on commodity exports. We construct two financial conditions indexes based on the reduced form IS model and the vector autoregression (VAR) model as surveillance tools to quantify the degree of the financial conditions. We find that real short-term interest rate and real effective exchange rate gap get a higher weight in the FCIs. Both business and financial cycles are often more pronounced in Mongolia, and financial condition is dependent of the financial and monetary policies in place. The analysis of the predictive power of the FCIs for business cycles shows that they have predictive information for the near-term economic activities. FCIs are also helpful in signaling inflation turning points.

• 국제학술발표논문집
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• The 3th International Conference on Construction Engineering and Project Management
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• pp.914-919
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• 2009

The research investigates for the relationship between the operating performances of the make-ready process and project production performance. To this end, the researchers proposed a metric of PCR (Percentage of Constraint Removal) to measure the make-ready performance. The study measured the production performance in two ways: production planning reliability and progress performance. We hypothesized that how well the make-ready process is performed has an impact on the degree of production performance. The statistical analyses are used to investigate that how operating performance of the make-ready process affects project production performance. The results of the regression analysis support our hypotheses (p<0.25) and correlation coefficients for the relationship between project production performance and make-ready performance are also significant (p<0.05).

• Asia Marketing Journal
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• 제18권4호
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• pp.51-76
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• 2017

Although much attention has been paid to customer satisfaction (CS) as a leading indicator of firm performance, few studies have investigated the role of CS distribution across individual customers. With 10 years of National Customer Satisfaction Index (NCSI) data in Korea, we examine the relationship between the variance of CS and key corporate performance measures such as revenue, profit, Tobin's q, and stock return. There are three main findings. First, we confirm the findings of previous studies that the average CS for a firm is related to the firm's economic performance. Second, we find a moderating effect of CS variance such that the relationship between the level of CS and firm performance is attenuated by the variance of CS. Finally, the variance of CS is found to directly affect firm performance over and above the CS level effect. More specifically, the variance decreases sales and stock return.

• 기술혁신연구
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• 제26권4호
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• pp.57-97
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• 2018

빅데이터는 2010년 이후 다양한 산업 분야에서 빠르게 확산이 진행되었다. 본 연구에서는 빅데이터가 확산되는 초기 과정에 대한 시계열 분석을 통해 빅데이터의 범용 기술 특징을 분석하였고, 각 산업의 확산 특성 차이에 대해 조사하였다. 빅데이터를 키워드로 하여 논문, 특허, 뉴스 데이터, 구글트렌드를 분석하여 선행 지수에 해당하는 데이터를 탐색하였고, 논문과 특허보다 뉴스와 구글트렌드가 2년가량 선행하는 트렌드를 보임을 확인하였다. 구글트렌드를 이용하여 국내와 미국, 일본, 중국의 국가별 도입시기와 확산 양산을 비교하였고, 뉴스 데이터를 통해 국내의 주요한 8가지 산업 분야에 대해 확산이 진행되는 과정을 정량적 그리고 사례를 바탕으로 분석하였다. 본 연구를 통해 빅데이터처럼 산업 전반에 걸쳐 영향을 주는 범용 기술이 어떻게 초기 확산이 이루어지는지에 대한 실증적 연구 방법을 제시하였고, 빅데이터가 국내에서 각 산업별 확산 속도 차이는 어디에서 비롯되는지 파악하였다. 본 논문에서 제시한 방법은 빅데이터 이외에 다른 기술의 확산 과정에도 분석할 수 있으며, 특정 국가내의 기술 키워드 확산에 해당하므로 개발도상국에서 외국으로부터 도입된 기술을 어떻게 받아들일지 분석하는데 사용 가능하다. 그리고, 기업 측면에서는 새로운 기술을 출시하고 이를 확산하고자 할 때 어떤 경로가 효과적인지 이해할 수 있다.

• The Journal of Asian Finance, Economics and Business
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• 제6권4호
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• pp.287-295
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• 2019

The study aims to build a model for evaluating the effectiveness of activities and the effectiveness of financial investments in high-tech industries in Kazakhstan. The development of high-tech industries plays an important role in the economic growth of a country. In this regard, it is relevant to study the effectiveness of financing the most important industry in Kazakhstan. The development of the high-tech sector ensures the efficient functioning of the national innovation system. High-tech enterprises are one of the competitive sectors that allow us to develop and implement leading-edge innovations with the goal of their subsequent commercialization domestically and abroad. The author defines the multicriteria of efficiency in a knowledge-based economy associated with achieving an economic effect with multivariate correlation of results with costs. A multivariate dynamic model, an integral indicator of performance, an integral indicator of cost-effectiveness is proposed. The assessment of the effectiveness of financial costs and performance indicators in all regions of Kazakhstan have the positive dynamics of indicators, as well as a high economic effect. The results of the study can be applied in regional management to adequately assess the effectiveness of high-tech organizations and the effectiveness of financial investments, contribution to ensuring the economic security of the region.

• Asian Pacific Journal of Cancer Prevention
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• 제16권11호
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• pp.4769-4775
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• 2015

Background: Hepatocellular carcinoma (HCC) is the fifth most prevalent cancer and thirdly leading cause of cancer-related death worldwide. The estimated risk of hepatocellular carcinoma is 15 to 20 times as high among persons infected with HCV as it is among those who are not infected, with most of the excess risk limited to those with advanced hepatic fibrosis or cirrhosis. Glypican3 (GPC3) plays a key role in relation to signaling with growth factors, regulating the proliferative activity of cancer cells. Glutamine synthetase (GS) catalyzes the synthesis of glutamine from glutamate and ammonia in the mammalian liver. GS was suggested as a specific marker for tracing cell lineage relationships during hepatocarcinogenesis. In normal liver, GS expression is seen in pericentral hepatocytes, but not by midzonal or periportal hepatocytes. In HCC, strong and diffuse GS expression in seen in tumor cells. Results: Glypican3 immunopositvity was highly specific and sensitive indicator for hepatocellular carcinoma as well as glutamine synthetase which was found to be a sensitive and specific indicator for development of hepatocellular carcinoma when compared to cirrhosis, liver cell dyspalsia and metastatic carcinomas. Statistical analysis revealed a significant association between GPC3 and GS with tumor size (P=0.003, p=0.006, respectively). Diffuse staining significantly associated with large tumor size while, focal and mixed staining was detected more with small tumor size. Studying the relation with tumor grade also revealed significant association between diffuse GPC3 and GS staining with high tumor grade. Diffuse staining was detected in 91.7% and 100% respectively of poorly differentiated specimens and only in 33.3% and 22.2% of well differentiated specimens. Conclusions: While using GPC3 and GS to screen for premalignant hepatic lesions remains controversial, our data suggest that GPC3 and GS may be a reliable diagnostic immunomarkers to distinguish HCC from benign hepatocellular lesions. However, negative immunostaining should not exclude the diagnosis of HCC.

• 컴퓨터교육학회논문지
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• 제16권1호
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• pp.73-80
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• 2013

정부는 최근 연구개발 패러다임 변화에 따라 미래 성장잠재력 확충 및 국가경쟁력 제고를 위하여 선진기술을 모방하는 추격형 R&D에서 탈피하여 선도형 R&D로의 변환을 추진하고 있다. 이에 따라 국가연구개발사업을 통한 기초 원천 연구분야 및 국가 중요핵심 기술에 대한 연구가 활발히 이루어지고 있어 이에 대한 보안의 중요성이 부각되어 다양한 보안진단 및 평가가 시행되고 있다. 그러나 기존 연구보안수준 평가는 보안관리 관점에서 도메인으로 분류하고 그에 따른 평가지표를 제시하여 연구자의 자율적인 연구보안평가 시 한계점을 노출하였다. 이에 본 논문에서 연구관리 프로세스 관점으로 도메인을 설정한 후 그에 따른 연구보안 평가지표를 설계하여 연구보안 수준의 자가진단에 효과적으로 활용할 수 있는 평가모델을 제시하였다.