• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.49 no.5
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• pp.425-435
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• 2021

It is imperative to examine the regulatory trends of leading overseas aviation authorities to accelerate the effort to integrate emerging new air vehicle concepts such as UAS and eVTOL into the existing national airspace system. Whilst EASA seems to react swiftly in relation to regulatory framework by proposing new sets of customised special conditions to cope with a growing demand to introduce new aircraft concepts, understanding of such movement lags behind mainly due to the complexity of EASA's regulation structure, not to mention EU's legal system. Witnessing this situation, this paper reviewed the legal system of the EU which forms the basis of EASA's regulation system together with its own recently published UAS regulations so as to contribute towards the improvement of the aviation regulatory framework.

• International Journal of Advanced Culture Technology
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• v.10 no.3
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• pp.146-155
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• 2022

The purpose of this study is to investigate the recyclability of Shenlong in China using SWOT. The main analysis results are as follows. First, provided that the company's current capacity utilization rate is seriously insufficient, reducing staff is one among the effective ways. Second, Shenlong should open a web store to cater to young people's online shopping behavior, and further expand the brand visibility using national mainstream media and online shopping platforms like Taobao and JingDong to market Dongfeng Peugeot and Dongfeng Citroen on the whole network. Third, under the premise of maintaining the present best-selling models, Shenlong should appropriately reduce the amount of models, adjust the assembly capacity ratio of every model and every displacement in real time per the newest market trends, increase the agility of auto companies' production, and timely meet the wants of domestic consumers. Fourth, dual-brand coordination and channel integration are very necessary, and also the profitability and profitability of dealers are going to be further improved, thereby increasing sales. Fifth, target building new energy leading products of Shenlong, strive to attain the forefront of the industry within the sales of recent energy vehicles within 5 years, and gradually expand new energy vehicle products from passenger vehicles to passenger vehicles and commercial vehicles. Finally, the marketing field of Shenlong Automobile should achieve "three major changes", that is, change from a goal-driven type to a demand-driven type, cancel the bundling of outlet invoicing goals and delivery incentive tiers; start from basic capabilities, and set pragmatic and challenging goals; focus Channels, to realize following the activation of outlets, and single store sales increase.

• Composites Research
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• v.35 no.6
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• pp.365-370
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• 2022

According to the rapid growth of electric vehicle (EVs) and E-mobility market, Li-ion batteries are one of the most progressive technologies. The demand of LIBs with high energy capacity, rate performance and fast charging is continuously increasing, hence high-performance LIBs should be developed. Si is considered as the most promising anode material to improve energy density because of its high theoretical capacity. However, Si suffers large volume chances during the charging and discharge process, leading to the fast degradation of cycle performance. Therefore, polymeric binders play a key role in electrochemical performance of Si anode by efficiently enduring the Si expansion and maintaining the binding networks in electrode. In this review, we explain the role of polymeric binders in electrode and introduce the anode binders with enhanced mechanical and chemical properties which can improve electrochemical performances of Si-based anode.

• Clinical and Experimental Pediatrics
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• v.65 no.4
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• pp.194-200
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• 2022

Background: Injury is the leading cause of death or disability in children and adolescents. Rates of deaths from injuries have recently declined, but studies of the occurrence of nonfatal injuries are lacking. Purpose: This study aimed to investigate nonfatal injuries in children and adolescents younger than 20 years based on data from the Korean National Health and Nutrition Survey, 2007-2018. Methods: A questionnaire survey was conducted to determine whether children and adolescents had experienced an injury requiring a hospital visit in the previous year. We investigated each injury's risk factors and characteristics. Results: Of a total of 21,598 children and adolescents, 1,748 (weighted percentage, 8.1%) experienced one or more injuries in the previous year. There was no yearly difference in the proportion of injuries experienced. Among the male subjects, 10.0% had an injury experience; among the female participants, 6.1% had an injury experience (P<0.001). The highest rate was 9.0% in children aged 1-4 years. In multivariate logistic regression analysis, male sex; having an urban residence; having restricted activity due to visual, hearing, or developmental impairment; and attention deficit/hyperactivity disorder were significant risk factors for injury experience. The characteristics of up to 3 injuries per patient were investigated, and 1,951 injuries were analyzed. Falls and slips accounted for 34.9%, collisions for 34.1%, and motor vehicle accidents for 11.3% of the total injuries. Ninety-six percent of injuries were unintentional, 20% caused school absences, and 10% required hospitalization. Conclusion: Among Korean children and adolescents, 8.1% experienced injuries at least once a year with no significant differences in incidence over the past 12 years. Greater attention and effort to prevent injuries are needed.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.45 no.4
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• pp.225-232
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• 2022

Recently, unmanned logistics delivery systems, such as UAV (Unmanned Aerial Vehicle, written as drone below) and autonomous robot delivery systems, have been implemented in many countries due to the rapid development of autonomous driving technology. The development of these new types of advanced unmanned logistics delivery systems is essential not only to become a leading logistics company but also to secure national competitiveness. In this paper, the application of the unmanned logistics delivery system was investigated in terms of market trends, overall technology level of last mile delivery drone and autonomous delivery robot. The direction of response to changes in the last mile delivery service market was checked through a comparison of the technological level between domestic companies that produce last mile devices and advanced foreign companies. As a result of this technology level analysis, the difference between domestic companies and advanced companies was shown using tables and figures to show their relative levels. The results of this analysis reflect the opinions of experts in the field of last-mile delivery technology. In addition, the technology level of unmanned logistics delivery systems for each country was analyzed based on the number of related technology patents. Lastly, insights for the technology level analysis of unmanned last mile delivery systems were proposed as a conclusion.

• Journal of Veterinary Science
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• v.23 no.2
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• pp.26.1-26.12
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• 2022

Background: Glutamate is the main excitatory neurotransmitter. Excessive glutamate causes excitatory toxicity and increases intracellular calcium, leading to neuronal death. Parvalbumin is a calcium-binding protein that regulates calcium homeostasis. Quercetin is a polyphenol found in plant and has neuroprotective effects against neurodegenerative diseases. Objectives: We investigated whether quercetin regulates apoptosis by modulating parvalbumin expression in glutamate induced neuronal damage. Methods: Glutamate was treated in hippocampal-derived cell line, and quercetin or vehicle was treated 1 h before glutamate exposure. Cells were collected for experimental procedure 24 h after glutamate treatment and intracellular calcium concentration and parvalbumin expression were examined. Parvalbumin small interfering RNA (siRNA) transfection was performed to detect the relation between parvalbumin and apoptosis. Results: Glutamate reduced cell viability and increased intracellular calcium concentration, while quercetin preserved calcium concentration and neuronal damage. Moreover, glutamate reduced parvalbumin expression and quercetin alleviated this reduction. Glutamate increased caspase-3 expression, and quercetin attenuated this increase in both parvalbumin siRNA transfected and non-transfected cells. The alleviative effect of quercetin was statistically significant in non-transfected cells. Moreover, glutamate decreased bcl-2 and increased bax expressions, while quercetin alleviated these changes. The alleviative effect of quercetin in bcl-2 family protein expression was more remarkable in non-transfected cells. Conclusions: These results demonstrate that parvalbumin contributes to the maintainace of intracellular calcium concentration and the prevention of apoptosis, and quercetin modulates parvalbumin expression in glutamate-exposed cells. Thus, these findings suggest that quercetin performs neuroprotective function against glutamate toxicity by regulating parvalbumin expression.

• The Korean Journal of Rheology
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• v.10 no.4
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• pp.217-226
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• 1998

The anisotropy caused by the fiber orientation, which is inevitably generated by the flow during injection molding of short fiber reinforced polymers, greatly influences dimensional accuracy, mechanical properties, and other quality of the final product. Since the filling stage of the injection molding process plays a vital role in determining fiber orientation, an accurate analysis of flow field for the filling stage is needed. Unbalanced filling occurs when a complex or a multi-cavity mold is used leading to development of regions where the fiber suspension is under compression. It is impossible to make an accurate calculation of the flow field during filling with the analysis assuming incompressible fluid. A mold with four cavities with different filling times was produced to compare the numerical analysis results with the experimental data. There was a good agreement between the experimental and theoretical results when the compressibility of the polymer melt was considered for the numerical simulation. The fiber orientation states for compressible and incompressible fluids were also compared qualitatively as well as quantitatively in this study.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.3
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• pp.57-64
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• 2020

The leading technologies of the ADAS (Advanced Driver Assist System) are ACC (Advanced Cruise Control), LKAS (Lane Keeping Assist System), and AEB (Autonomous Emergency Braking). LKAS is a system that uses cameras and infrared sensors to control steering and return to its running lane in the event of unintentional deviations. The actual test is performed for a safety evaluation and verification of the system. On the other hand, research on the system evaluation method is insufficient when an additional steering angle is applied. In this study, a model using Prescan was developed and simulated for the scenarios proposed in the preceding study. Comparative analyses of the simulation and the actual test were performed. As a result, the modeling validity was verified. A difference between the front wheels and the lane occurred due to the return velocity. The results revealed a maximum error of 0.56 m. The error occurred because the lateral velocity of the car was relatively small. On the other hand, the distance from wheels to the lanes displayed a tendency of approximately 0.5 m. This can be verified reliably.

• Journal of Korean Society of Transportation
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• v.25 no.1 s.94
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• pp.109-119
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• 2007

Increasingly, the emphasis in regional Passenger rail Planning is finding ways to more efficiently use existing facilities, with particular attention being Paid to Policies designed to spread Peak-Period travel demand more evenly throughout the week with consideration of train classification. In this context the individual's choice of time to travel is of crucial significance. This paper investigates the use of multinomial logit analysis to model ridership by rail classification using data collected for travel from Seoul to Busan during the one week in October 2004. The Particular model form that was successfully calibrated was the multinomial logit (MNL) model : it describes the choice mechanism that will Permit rail systems and operations to be planned on a more reliable basis. The assumption of independently and identically distributed(IID) error terms in the MNL model leads to its infamous independence from irrelevant alternatives (IIA) property. Relaxation of the IID assumption has been undertaken along a number or isolated dimensions leading to the development of the MNL model. For business and related rail travel patterns, the most important variables of choice were time and frequency to the chosen destination. The calibrated model showed high agreement between observed and Predicted market shares. The model is expected to be of use to railroad authorities in Planning and determining business strategies in the Increasingly competitive environment or regional rail transport.

• Animal cells and systems
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• v.1 no.4
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• pp.595-602
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• 1997

Treatment of newborn female rats with gonadal steroids induces permanent sterility in adulthood. We investigated the alteration in expression patterns of gonadotropin-releasing hormone (GnRH) and luteinizing hormone (LH) in neonatally estrogenized sterile rats (ESR). Newborn female rats received daily injections of 17${\beta}$-estradiol (E, 10 ${\mu}$g) from the day of birth (day 1) to postnatal day 5. Controls were subjected to vehicles over the same period. All animals were sacrificed on week 7 after birth. Hypothalamic GnRH mANA levels were markedly higher in all ESR than in controls, while hypothalamic GnRH contents in ESR increased in proportion to the frequency of daily administration of E. However, both pituitary LH6 mRNA and serum LH levels were inversely decreased by the same treatment. The data indicate that neonatal exposure of E equally elevates the expression of GnRH gene, but reduces the secretion of GnRH, accordingly leading to attenuation of LH6 gene expression and circulating LH levels. The temporal effect of E and/or progesterone (P) on GnRH and LH6 mRNA levels was also examined in ESR. Newborn female rats were daily injected with E (10 ${\mu}$g) or vehicle for five successive days from day 1 and ovariectomized at week 5. They were implanted with E (235 ${\mu}$g/ml) two days prior to week 7, injected with P (1 mg) 42 h later, and sacrificed 7 h after P administration. In ovariectomized controls, hypothalamic GnRH mRNA levels were dropped to half by treatment of E and restored by subsequent treatment of P. The negative feedback action of E on GnRH mRNA levels observed in ovariectomized rats was completely blocked by neonatal exposure of E. The change in pituitary LH mRNA levels was similar to that in hypothalamic GnRH mRNA levels. Taken together, the results suggest that neonatal treatment of E alters the synthesis and release of GnRH in adulthood and furthermore blocks the negative feedback regulation of E which occurs normally after ovariectomy.