• 대한수의학회지
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• 제36권3호
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• pp.709-718
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• 1996

This experiment was carried out to clarify the effect of lead poisoning on the lead and essential trace elements homeostasis of tissues in rats. Fifty female Wistar rats, 7 weeks old, were divided into four experimental groups(B, C, D, and E) and a control(A). The four experimental groups received diets contaminated artificially with 10 (B group), 100 (C group), 1,000 (D group) and 5,000 (E group) ${\mu}g/g$ of lead as lead acetate, respectively. The control group received normal diet. Rats were necropsied on the 4th or 8th week of experimental periods and heart, liver, spleen, kidney, muscle, lung and hair were taken. The tissues were analysed for lead, copper, zinc, iron and calcium content by atomic absorption spectrophotometry. From these experiments following results ware obtained ; In C group, lead content of the heart, liver, kidney and hair were significantly increased both on the 4th and 8th week of experiment. In D and E group, lead content of all tissues including heart, liver, spleen, kidney, muscle, hair and lung were significantly increased in accordance with the lead contamination both on the 4th and 8th week of experiment. In C group, copper content of tissues were significantly increased in the heart, liver, kidney and lung on the 4th week and all tissues on the 8th week of experimental periods. In D and E group, copper content of the liver were significantly increased both on the 4th and 8th week of experiment. But the copper content of tissues were gradually decreased compared with C group in accordance with the lead contamination. Especially the content in spleen, heart or kidney were significantly decreased compared with the control group. The zinc content of kidney, heart, or spleen were decreased in D and E groups whereas the iron and calcium content showed no significant change.

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 1995년도 제47차 추계 학술대회 연제집
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• pp.379-380
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• 1995

• Journal of Preventive Medicine and Public Health
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• 제19권1호
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• pp.76-84
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• 1986

Analyses of lead and zinc were made by means of standard addition method using atomic absorption spectrophotometer(Baird Ltd., Model A5100) with flameless method for lead and flame method for zinc. The blood samples used were merely diluted with triton x-100, because it was simple, rapid and minimal risk of contamination. Mean recovery rate for lead added to the blood ranged from 97.7 to 101.3% with coefficient of variation ranging from 1.9 to 10.7%, and that for the added zinc ranged from 99.0 to 102.2% with coefficient of variation ranging from 2.1 to 9.1%. In repeated measurements of zinc in the blood, good reproducibility and interindividual variation were proved(p<0.01). In comparison of the lead and zinc concentrations in the blood determined by the standard addition method and standard method, there were good correlations between 2 sets of data (r=0.9731 for lead and r=0.9785 for zinc), although lead levels were estimated higher by the former method(p<0.01) and zinc levels by the latter method(p<0.01). It can be concluded that lead and zinc levels in blood standard addition method is reliable for determination of lead and zinc in the blood with good accuracy and reproducibility.

• 한국환경보건학회지
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• 제32권2호
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• pp.186-191
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• 2006

Metal contamination of medicinal herbs is of growing concern because of their potential adverse health effects. In this study, metal exposures were estimated and their potential health risks were preliminarily evaluated using available data including metal contamination levels and consumption estimates of herbal medicine in Korea. Consumption and contamination data of 34 medicinal herbs abundantly used in Oriental medicine in Korea were used in this study. Lead, mercury, arsenic, cadmium, cobalt, and chrome were identified as contaminants of potential health concerns. Even based on a conservative exposure scenario, i.e., consuming 5 times more herbal medicine with 95th percentile contamination levels, health risks associated with herbal medicine consumption were estimated to be minuscule. Herbal consumption was 0.3% of the provisional tolerable daily intake levels recommended by Joint Expert Committee on Food Additives (JECFA) of WHO/FAO. However, it should be noted that there are several important assumptions and uncertainties associated with this evaluation: This study was conducted for only 34 types of medicinal herbs of which consumption and metal contamination data were available. In addition, there are no reliable herbal medicine consumption data among Korean population. The pattern and amount of herbal (medicine) consumption in Korea need to be investigated in order to conduct more refined risk assessment associated with metal contamination in medicinal herbs.

• 지질공학
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• 제3권3호
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• pp.241-252
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• 1993

미국 위스컨신주 도어 지역의 지하수내에서 납성분이 시기적, 장소적으로 불규칙하게 산출되었다. 본 연구에서, 지하수의 납성분의 오염도를 나타내주는 지시자들(검출빈도, 납성분의 평균, 최고 검출농도)과 지하수의 납 오염에 관계가 있을 가능성이 있는 7개의 독립변수들과의 상관계수가 계산되었다. 이 관계의 통계적 중요성은 t-test에 의하여 90%의 신뢰도에서 이루어졌으며, 이 지역에 산재하는 농약(lead-arsenate)의 처리장소가 지하수내 납성분의 요염 원인임을 통계학적으로 입증하였다. 납성분으 산출농도가 높았던 5개의 가정우물로부터 총 112개의 지하수시료가 채취분석되었다. 납성분은 $0.45{\;}\mu\textrm{m}$의 공극 크기를 지닌 여과지에 걸러진 미립자에서 검출되었으며, 여과액에서는 검출되지 않았다. 이러한 결과는 납성분이 이 지역의 지하수내에서 미립자이 상태로 존재함을 지시한다. 따라서, 이 지역에서 납성분의 불규칙한 산출은 미립자상의 납이 수평과 수직으로 발달된 파쇄대와 같은 유동경로를 따라 이동하면서 나타나는 현상으로 고려된다.

• 대한간호학회지
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• 제16권1호
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• pp.67-80
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• 1986

The use of intravenous solutions for fluid replacement has become an integral part of patient care, This widespread use of intravenous solutions has increased the risk of contamination that can lead to septicemia and phlebitis. The literature regarding contamination of in use intravenous solutions recommends a standard 24-hour time limit on the use of these fluids. But the desings of these studies did not incorporate a time variable related to contamination. In other studies, however, time was a manipulated variable: but data regarding the onset of contamination were conflicting. Because published reports conflict with regard to a time standard related to the use of intravenous therapy, additional empirical data are needed upon which to base the standards of care regulating use of intravenous therapy. This study investigated rate of contamination in simulated in-use intravenous solutions to obtain data from which to recomend a standard time period for the administration of intravenous solutions. In this study samples were drawn from 60 bottles of 5% D/W solution at predetermined time intervals over 48 hours and samples were inoculated to Thio-glychollate Broth. After 10 days' culturing in that Broth, samples were cultured on blood agar plates for 18∼48 hours to determine the rate of contamination. was found at all time Period, regardless of the presence or absence of nurse's gloving in the preparation of fluids, the location in which the experimentations were performed, the contamination level of surrounding air, or the length of time during which solutions were opened. Data from this study support the use of a 48-hour time period on which to base the standard involved in ready-to-use simple intravenous solutions without additives. In emergency departments and critical care areas where intravenous solutions are prepared in advance, the suggested time standard supported by the data generated from this study is 48 hours, not 24 hour. Data from this study support a 24-hour time standard for changing in-use intravenous solutions when the contamination results from the manipulation of intravenous infusion system by hospital personnel, or from some other exogenous sources during administration. Because contamination that does occur within 48 hours in intravenous solutions must be introduced from some exogenous sources, further empirical studies based on the identification of sources of contamination and factors that affect the rate of contamination, are needed to investigate the currently employed standard of intravenous therapy and to provide the patient with more efficient and safer intravenous thereapy.

• 한국환경과학회지
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• 제31권2호
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• pp.103-116
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• 2022

Heavy metal contaminations were investigated in fishes inhabiting the basins of Andong, Imha and Yeongju dam basins along the upper stream of the Nakdong river. The characteristics of heavy metals contamination in fish were investigated based on sampling sites located in the Andong dam basin. The muscle tissue was analyzed for 267 objects of 26 species from the Andong dam, 50 objects of 17 species from Imha dam, 38 objects of 9 species fromYoungju dam basin.The type and amount of heavy metals concentrated in the body of the fishes was found to be species-dependent. The heavy metal species which contamination increase through the Seokpo smelter are chromium, zinc, cadmium, and lead, and these are very likely the influence of the smelter. The concentration of eight heavy metals in fish from the Andong dam basin was higher than that in fish from the Imha and Youngju dam basins; the values for zinc, arsenic, and cadmium were significantly higher. However, mercury and lead exhibited high values in the Imha and Yeongju dam basins, respectively.

• 한국초전도ㆍ저온공학회논문지
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• 제21권2호
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• pp.31-35
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• 2019

Andong-dam was built up in 1967 and it is one of the biggest dams in Korea. Previous studies showed that the sediments are highly contaminated with heavy metals such as arsenic, cadmium, and lead. Many research projects are going on to find out the source of the contamination, to evaluate the toxicities to ecosystem, to estimate the volume of sediment to be treated and to find out a good remediation method. Reports show that the sediment is highly contaminated and the main contamination source is supposed to be abandoned mines and a zinc refinery located upper stream of the river. A magnetic separation has been tested as a treatment method for the dredged sediment. Lab scale test showed that the magnetically captured portion is about 10% in weight but the contamination of heavy metal is much higher than the contamination of the passed portion. This indicates that a magnetic separation could be applied for the purpose of reduction of sediment to be treated and for increasing the volume of low toxic sediments which can be dumped as general waste. A magnetic separation using a HGMS has been tested for the sediment with variable magnetic field and the results showed the higher magnetic field increase the captured portion but the concentrating effect of heavy metal was weakened. Further study is needed to establish a useful technology and optimization between decontamination and reduction of sediment volume.

• 한국지반공학회논문집
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• 제22권7호
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• pp.45-54
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• 2006

전기비저항콘은 현장에서 지반의 오염대를 조사하는데 상대적으로 경제적인 비용으로 적용될 수 있다. 그러나, 전기비저항 결과만에 의한 해석은 정량적 데이터베이스의 부족과 함수비 등의 다른 지반공학적 영향인자들에 의해 모호한 결과를 나타낼 수 있다. 본 연구에서는 지반오염조사에서의 전기비저항 측정기법을 보완하기 위하여 정전용량 측정기법을 도입하여 중금속과 유류로 오염된 지반에서의 적용성을 평가하고자 하였다. 함수비와 오염물질의 종류에 따른 전기비저항과 정전용량의 변화를 평가하기 위하여 실내모형시험을 수행하였으며, 그 결과 전기비저항과 유전상수를 통시에 측정하여 분석함으로써 오염대의 감지에 신뢰도를 높일 수 있는 것으로 나타났다. 전기비저항과 정전용량 측정기법은 중금속으로 오염된 포화지반과 지하수대 상부에 존재하는 디젤유 오염층을 감지하는 데 적용성이 높은 것으로 나타났다.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2003년도 추계학술대회
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• pp.1590-1595
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• 2003

Direct drive servovalve(DDV) is a kind of one-stage valve since the rotary motion of DC motor is directly transferred to the linear motion of valve spool through the link. Since the structure of DDV is simple, it is less expensive, more reliable and offers reduced internal leakage and reduced sensitivity to fluid contamination. However, the flow force effect on the spool motion is significant such that it induces large steady-state error in a step response. If the proportional control gain is increased to reduce the steady-state error, the system becomes unstable. In order to satisfy the system design requirements, the lead-lag controller is designed using the complex method that is one kind of constrained direct search method.