• The Journal of Advanced Prosthodontics
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• v.15 no.4
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• pp.189-201
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• 2023

PURPOSE. The aim of this study was to investigate the mechanical properties of three-dimensional (3D) printed denture base resin incorporating microcapsules containing plant essential oils. MATERIALS AND METHODS. Denture base specimens containing up to 3% w/v essential oil microcapsule powders (MCPs), i.e., eucalyptus, geranium, lavender, menthol, and tea tree, in two resins (Detax and NextDent 3D+) were 3D printed using two printers (Asiga and NextDent 5100). The dispersion and interaction of the MCPs in the resin were assessed by SEM while the mechanical properties of the incorporated denture base including flexural strength (MPa), flexural modulus (MPa), Vickers hardness (VHN), and surface roughness (Ra) were also subsequently evaluated. Statistical analysis of any differences in mean values was determined using a two-way ANOVA with Tukey's post hoc testing (α = .05). RESULTS. The spherical shape of the MCPs was maintained during the mixing and polymerization/printing process. However, the Detax-Asiga group showed significant agglomeration of the MCPs even at the lowest MCP concentration levels (0.5% w/v). Overall, as the microcapsule concentration increased, the mean flexural strength decreased, though the menthol MCP groups remained compliant with the ISO standard. The flexural modulus and harness remained relatively unchanged, and the flexural modulus complied with the ISO standard regardless of the MCP concentration. Surface roughness increased with the addition of the MCPs but also remained below that required for clinical acceptance. CONCLUSION. Incorporation of microencapsulated plant essential oils into 3D printed denture base resin was successfully achieved. While incorporation negatively influenced flexural strength and surface roughness, little effect on flexural modulus and Vickers hardness was demonstrated.

• Journal of Digital Convergence
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• v.14 no.8
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• pp.547-553
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• 2016

This study was conducted to look at the antimicrobial synergistic effect of blended oil into the target skin flora. The essential oils used in antimicrobial test were 100% eucalyptus (EU), lemon (LE), lavender (LA) and four blended oils, EU+LE, LE+LA, EU+LA, and, EU+LE+LA in ratio of 1:1 and 1:1:1 respectively. As a result, LE showed the highest, LA showed the lowest antimicrobial activity among single oil group. In blended oil group, antimicrobial activity of the EU + LA showed significantly increasing effect than the sum of the antimicrobial activity of the single oil. However, the antimicrobial effects of the blend of three oils did not show any synergistic effect. This result showed that the interaction between the chemical components constituting the oil than the number of blended oil seems more significant on the synergistic effect. Therefore, blending essential oil based on scientific evidence becomes more necessary in the future.

• Journal of Veterinary Clinics
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• v.31 no.3
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• pp.180-193
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• 2014

Allergic contact dermatitis (ACD) is an inflammatory skin disease and regarded as a prototype of T-cell mediated delayed-type hypersensitivity reactions. Aroma Oil Complex (AOC) is composed of lavender true oil, chamomile roman oil and tea tree oil. This study was performed to assess the effects of AOC in a canine model of ACD. ACD was induced on the back of dogs induced by sensitization and repeated application by 2,4-dinitro-1-chlorobenzene (DNCB). Topical treatment of AOC was applied once a day for 8 days and skin biophysical parameters including transepidermal water loss (TEWL), skin hydration, skin thickness and erythema index, were measured every two days during experimental periods. Histopathology and immunohistochemistry were performed to evaluate the anti-inflammatory effect. In skin biophysical parameters, TEWL, skin hydration, skin thickness and erythema index were significantly increased, with a maximum increase appeared on day 2 (p<0.05). After the completion of AOC treatment, skin biophysical parameters were significantly reached those of baseline in a time-dependent manner (p<0.05). In histopathology, marked increases of epidermal thicknesses were induced after DNCB challenge with numerous inflammatory cell infiltrations and edematous changes, decreases of connective tissue occupied regions in dermis. In addition, marked increases of cytokine - tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) and interferon-${\gamma}$ (IFN-${\gamma}$)-immunoreactivities in the dermis and of apoptotic markers - caspase-3 and PARP-immunoreactivities in the epidermis were observed in DNCB control as compared with intact control, respectively (p<0.01). The decrease of infiltrated inflammatory cells and related decreases of pro-inflammatory cytokine immunoreactivities were observed in AOC treated skin (p<0.01). Based on these findings, AOC may have anti-inflammatory and alleviatory effects in the allergic contact dermatitis.

• Science of Emotion and Sensibility
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• v.6 no.1
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• pp.39-45
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• 2003

To investigate the changes of cortico-cortical connectivity during odor stimulation of subjects classified by occupations, the mutual information content of EEGs was examined, for general workers, perfume salespersons and professional perfume researchers. Analysis of the averaged-cross mutual information content (A-CMI) from the EEGs revealed that, among the professional perfume researchers,. changes in the A-CMI values during odor stimulation were more apparent in the frontal region of the brain, although for the general workers group and perfume salespersons group such changes were more conspicuous in the overall posterior temporal, parietal and frontal regions. These results indicate that the brains of professional perfume researchers respond to odors mainly in the frontal region, reflecting the function of the orbitofrontal cortex (OFC) due to the occupational requirement of these subjects to discriminate of identify odors. During odor stimulation, the perfume salespersons, although relatively more exposed to odors than the general workers, showed similar changes to the general workers. A-CMI value is in inverse proportion to psychological preferences of the professional perfume researchers and perfume salespersons, but this is not the case with the general workers. This suggests that functional coupling for people who are occupationally exposed to odors may be related to odors nay be related to psychological preference.

• Journal of Korean Academy of Nursing
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• v.36 no.7
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• pp.1123-1134
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• 2006

Purpose: The purpose of this study was to identify the effects of aromatherapy on blood pressure and stress responses of clients with essential hypertension. Method: There were fifty-two subjects divided into an essential oil group, placebo group, and control group by random assignment. The application of aromatherapy was the inhalation method of blending oils with lavender, ylangylang, and bergamot once daily for 4 weeks. To evaluate the effects of aromatherapy, blood pressure and pulse were measured two times a week and serum cortisol levels, catecholamine levels, subjective stress, and state anxiety were measured before and after treatment in the three groups. Data was analyzed by repeated measures of ANOVA, one-way ANOVA, and $X^2-test$ using the SPSS 10.0 program. Results: The blood pressure, pulse, subjective stress, state anxiety, and serum cortisol levels among the three groups were significantly statistically different. The differences of catecholamine among the three groups were not significant statistically Conclusion: The results suggest that the inhalation method using essential oils can be considered an effective nursing intervention that reduces psychological stress responses and serum cortisol levels, as well as the blood pressure of clients with essential hypertension.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.18 no.4
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• pp.480-487
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• 2011

Purpose: This study was done to examine the effects of aroma hand massage on stress response and sleep in hospitalized elderly patients. Methods: A non-equivalent pre-and post-test design was used. Sixty-six hospitalized patients were recruited using a convenience sampling method and assigned to the experimental (n=34) or the control group (n=32). For the experiment, bergamot, lavender, and roman camomile oil were mixed in 2:1:1 ratio to provide aroma hand massage to both hands of each patient in the experimental group for 5 minutes per hand, for 3 days. Post-test data collection was conducted three days after completion of the hand massage. Results: The experimental group had significantly lower stress score (t=-2.648, p=.010, and anxiety scores (t=-4.166, p=.000), and higher sleep measurement scores (t=2.328, p=.023) than those in the control group. Conclusion: These results indicate that short-term application of aroma hand massage for hospitalized elderly patients has a positive effect on hospitalization stress, anxiety, and sleep. Therefore, aroma hand massage should be applied as a nursing intervention to reduce stress response and enhance sleep in elderly hospitalized patients.

• The Journal of Korean Academic Society of Nursing Education
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• v.13 no.2
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• pp.169-176
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• 2007

Purpose: The purpose of this study was to verify the effect of aromatherapy hand massage on stress responses and serum Immunity of RN's before the night duty. Method: The data were collected during the period from Oct. 10 to Nov. 15, 2005 at S-Hospital in Seoul. There were forty-eight subjects, 24 for the experimental and 24 for the control group. A Pre & post test were conducted to measure pulse rate, perceived stress(level and score) and a blood sample for cortisol and IgA. In the experimental group, lavender and geranium were used. Data were analyzed by descriptive statistics, $x^2$-test and t-test with SPSS program. Result: The pulse rate was reduced but there were no significant differences between the two groups. Scores of subjective stress(VAS) decreased significantly after aromatherapy hand massage and the level of serum Cortisol was reduced significantly. The level of serum IgA was elevated significantly. Conclusion: Aromatherapy hand massage could be a useful intervention to reduce stress and elevate the immunity of nurses during the night duty.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.17 no.4
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• pp.539-547
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• 2010

Purpose: This study was done to determine the effects of aromatherapy on anxiety and discomfort for patients who were having colonoscopy. Methods: The study used a nonequivalent control group non-synchronized design. The participants were 48 people who were undergoing colonoscopy in a university hospital. The experimental group inhaled a blend of essential oil with neroli, camomile, lavender and lemon through an aroma stone for 5minutes before the examination. Then the aroma stone was put on the side of the pillow to spread the aroma scent in the room. The experimental group could inhale the aroma scent as soon as they came into the room and during the examination process. The control group received only fundamental nursing care. Results: Aromatherapy significantly decreased VAS anxiety. There were also significant differences in facial change and, tone change for objective discomfort. But there were no significant differences in subjective discomfort between the groups nor were there any significant differences in vital signs. Conclusion: Aromatherapy was perceived as an useful intervention to reduce anxiety and objective discomfort of patients receiving colonoscopy. The results of this study could be utilized as a clinical nursing intervention.

• Women's Health Nursing
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• v.14 no.1
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• pp.28-35
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• 2008

Purpose: The study was performed to evaluate effects of aroma therapy on the anxiety, blood pressure and pulse of uterine leiomyoma patients before surgery and to apply it as the actual nursing intervention. Method: From Aug1st to Nov. 30th, 2007, the experimental group (n=30) and the control group (n=30) were selected in 1 hospital, Busan. Lavender and Bergamot oil mixed together at a 3:2 ratio was applied to the experimental group two times at 8-9 pm the day before surgery and twice 30 minutes before the surgery. Anxiety, VAS, blood pressure, and pulse were measured to evaluate the effects of aroma therapy. The data analysis was done using the SPSS/PC 12.0 program using chi-square test and t-test. Results: Hypothesis 1 was supported. The VAS of the experimental group was lower than control group after aroma therapy. Hypothesis 2 was partly supported. The systolic blood pressure and pulse of experimental group was significantly decreased, but diastolic blood pressure wasn't difference. The VAS, systolic blood pressure and pulse of control group were increased. Conclusion: The study verified that the aroma therapy is a very effective nursing intervention that can reduce anxiety before surgery. It is recommended to apply aroma therapy actively to patients experiencing anxiety before surgery procedure.

• Korean Journal of Adult Nursing
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• v.22 no.2
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• pp.153-160
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• 2010

Purpose: The purpose of this study was to investigate the effects of aromatherapy on stress, fatigue, mood, and vital signs of the nurses in the operating rooms. Methods: The data were collected from September 2007 to February 2008 in the operating room at K hospital located in Seoul, Korea. A total of 48 nurses were recruited. Among them, 25 nurses were randomly assigned to an experimental group and 23 were assigned to a control group. Experimental group was provided with aroma inhalation by necklace which had essential oil mixture of 0.2 cc. For aroma inhalation, Lavender, Zeranium and Mazoram were mixed in ratio of 5:3:2. In order to test the effectiveness of aroma inhalation, the pretest and posttest results for stress, fatigue, mood, and vital signs were compared between the experimental group and the control group. The data were analyzed by unpaired t-test and ANCOVA using the SPSS/WIN 15.0 program. Results: There were statistically significant decreases in the stress and fatigue scores, and increase in the mood scores and showed significant relaxation in the vital signs after the aroma inhalation. Conclusion: The aromatherapy had the positive effects on stress, fatigue, mood, and vital signs.