• Journal of Plant Biology
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• 제27권1호
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• pp.15-24
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• 1984

Leaf venation of 12 species of Lauraceae in Korea, native or introduced, was investigated and described by the use of Soft X-Ray. They could be grouped by the venation types, such as, 1. Actinodromous; Lindera obtusiloba, 2. Acrodromous; Cinnamomum camphora, C. japonicum, C. loureirii, 3. Brochidodromous having strongly developed basal secondary vein; Neolitsea aciculata, N. sericea, 4. Brochidodromous hoving irregulary branched secondary vein; Lindera erythrocarpa, L. glauca, 5. Brochidodromous having weak marginal loop; Machilus thunbergii, M.Japonica, 6. Brochidodromous having typical venation; Iozoste lancifolia, Litsea japonicum. This grouping corresponded with current classifying system at genus level except for genus Lindera, and supported Nakai's system at Tribe level. They also showed a gradual transition from brochidodromous to actinodromous types, but to certify the systematic value of this transition warrented more study. Identifying key for the species could be made by the venation type.

• Journal of Plant Biology
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• 제27권3호
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• pp.149-162
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• 1984

Anatomical characters of the secondary xylem in roots of Lauraceae, including 6 genera and 13 species grown in Korea, were studied systematically. Lauraceors members studied anatomically possess characters of the secondary xylem that are in the main more specialized than those found in the primitive angiosperm families. The specialized characters are as follows; (1) mostly solitary pores with some radially multiples, (2) mostly simple perforation plates and partially scalariform perforation plates in all species, (3) slightly oblique end wall of vessel element, (4) predominantly alternate intervascular pitting, (5) paratracheal axial parenchyma in all species, (6) heterogeneous II or III vascular rays. It is considered that the series of specialization in this family from the perforation plates and angle of end wall to the vessel axis is as follows; MachiluslongrightarrowNeolitsealongrightarrowLinderalongrightarrowCinammomumlongrightarrowIozostelongrightarrowLitsea.

• Journal of Plant Biology
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• 제27권3호
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• pp.129-138
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• 1984

Floral structures of 11 korean lauraceous species belonging to six genera have been studied. Machilus is a primitive genus having relatively large bisexual flower, six tepals and staminodes in fourth whorl of stamen. The flowers of Neolitsea are highly reduced state as unisexual flower, six stamens arranged to three whorls and no staminode in the flower, so regared as more advanced group. Intrafamilial classification systems of Nakai (1939) and Pax (1891) are more reasonable but still have some discrepancies with results. The origin of tepals of this group has been a long controversial problem; whether the differentiation of tepals occur. Teratological study of Lindera erythrocarpa, inner tepals of this group must be originated from the staminode and outer tepals from leafy tepals. Although morphological differentiation does not sitll occur, inner and outer whorls of tepals are originated through different way.

• Natural Product Sciences
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• 제25권1호
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• pp.23-27
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• 2019

From the pericarps of Litsea japonica (Thunb.) Jussieu, eighteen butanolide derivatives (1 - 18) were evaluated for their cytotoxic activity against HeLa, HL-60, and MCF-7 cells. Compounds 1-9 with 2-alkylidene-3-hydroxy-4-methylbutanolides structure exhibited cytotoxic activities against cancer-cell lines. Among them, compound 8 (litsenolide $D_2$) exhibited the most potent cytotoxicity against the tested cell lines, including HeLa, HL-60, and MCF-7, with $IC_{50}$ values of $17.6{\pm}1.3$, $4.2{\pm}0.2$, and $12.8{\pm}0.0{\mu}M$, respectively. Compound 8 induced apoptosis in a dose-dependent manner. Annexin V/Propidium Iodide (PI) double staining confirmed that 8 effectively induced apoptosis in MCF-7 cells. To the best of our knowledge, we have reported cytotoxic activity of butanolides from L. japonica against these cancer-cell lines for the first time.

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.372.1-372.1
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• 2002

AIzelin (1) and quercitrin (2) isolated from the EtOAc-soluble fraction of the leaves of Litsea japonica Jussieu (Lauraceae) showed inhibitory activity against classical pathway complement system with 50% inhibitory concentration ($IC_{50}$/) values of 112.2 and 198.2 $\mu\textrm{g}$/$m\ell$. respectively. For the structure-activity relationship of flavonoids on anti-complement system. myricitrin (3) from JUQ/ans mandshurica Maximowicz (Juglandaceae) also tested anti-complement activity. while this was devoid of any significant activity. (omitted)

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.195.2-195.2
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• 2003

The CH$_2$Cl$_2$ fraction of the bark of Machilus thunbergii Sieb. et Zucc. (Lauraceae) significantly protected primary cultures of rat cortical cells exposed to the excitotoxic amino acid, L-glutamate. Several lignans including (-)-isoguaiacin, meso- dihydroguaiaretic acid, machilin A, (+)-galbelgin, licarin A, (-)-sesamin, and (+)-guaiacin were isolated from the CH$_2$Cl$_2$ fraction using by bioactivity-guided isolation techniques. Among these lignans, (-)-isoguaiacin, meso-dihydroguaiaretic acid, licarin A and (+)-guaiacin had significant neuroprotective activities against glutamate-induced toxicity in primary cultures of rat cortical cells at concentration ranging from 0.1 ${\mu}$M to 10.0 ${\mu}$M. (omitted)

• 한국자원식물학회지
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• 제31권5호
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• pp.423-432
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• 2018

본 연구는 녹나무과 10종의 추출물이 Propionibacterium acnes의 억제활성에 미치는 영향을 분석하여 새로운 천연 항균소재를 개발하기위해 수행되었다. 실험재료는 완도와 제주도에서 채집하였으며, 부위(잎, 가지), 용매(증류수, 80% 에탄올, 100% 메탄올) 및 초음파 추출시간(15, 30, 45분)에 따른 조추출물의 항균활성을 agar diffusion method로 조사하였다. 대조구로는 합성항균제인 methylparaben과 phenoxyethanol 0.4, 1, 2, 4 mg/disc를 사용하였다. 연구에 사용된 10종의 모든 추출물에서 억제활성을 보였으며, 여드름균에 대한 항균작용을 확인할 수 있었다. 이 중 월계수는 80% 에탄올에 45분간 추출한 조건에서 20.2 mm의 생육억제환을 나타내어 가장 우수한 여드름균에 대한 항균작용을 확인할 수 있었다. 월계수 잎을 100% 메탄올을 용매로 초음파 30분 추출한 다음n-hexane, chloroform, ethyl acetate, n-butanol 그리고 water 순으로 용매 분획하여 항균활성을 비교분석하였다. 결과, butanol 분획물을 제외한 모든 분획물에서 10.0 mm 이상의 억제환이 형성되었다. 그중 ethyl acetate 분획물에서 억제환이 13.3 mm로 가장 컸으며, 조 추출물(10.2 mm)과 대조구인 phenoxyethanol (12.5 mm)에 비해서도 유의적으로 우수한 억제활성을 나타내었다.

• 생약학회지
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• 제38권4호
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• pp.382-386
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• 2007

Cinnamomi Cortex (Lauraceae), the dried bark of Cinnamomum cassia BLUME, has been used as traditional Chinese medicine for its stomachic, astringent, carminative, antispasmodic, antibacterial, antifungal properties. Four compounds were isolated from the MeOH extract of Cinnamomi Cortex, and their structures were identified as trans-cinnamic acid (1), ${\beta}-sitosterol$ (2), bis(2-methylheptyl)phthalate (3), coumarin (4) by comparison of their physical and spectral data with those reported in the literature. These compounds were tested melanogenesis inhibitory effect on B-16 mouse melanoma cell lines. Among them, trans-cinnamic acid (1) showed the most potent inhibitory effect on melanogenesis with $IC_{50}$ value of $13{\mu}g/ml$. Arbutin, positive control, exhibited an $IC_{50}$ value of $29{\mu}g/ml$.

• 한국자원식물학회지
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• 제1권1호
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• pp.53-71
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• 1988

전남지역의 명산중의 하나인 백운산 지역에 분포되어 있는 한약자원 식물을 수집 및 분류하여 약용작물로 재배하기 위한 기초자료로 활용하고자 이 지역의 한약자원 식물의 분포를 조사한 결과는 다음과 같았다. 1. 백운산에 분포되어 잇는 약용자원은 60과 250종으로 분류되었다. 2. 분포수종중 과본류는 161 종 목본류 89종이 분포되어 있었다. 3.과본류는 사삼, 도라지, 쑥, 엉겅퀴, 질경이, 차조기, 쇠무릎, 반하, 하수오, 결명자, 용담초, 맥문동, 하고초, 둥글레, 참마, 칡 등이 많이 분포되어 있었고, 목본류로는 굴피나무, 가래나무, 호두나무, 후피향나무, 모란, 이팝나무, 쥐똥나무, 누리장나무, 고로쇠나무, 비자나무, 삼나모, 때죽나무, 모과나무 등이 한약재료로 많이 사용되는 것들이었다.

• 한국자원식물학회지
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• 제1권1호
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• pp.23-32
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• 1988

전남지역에서 3대 명산중의 하나인 모후산 지역에 분포되어 있는 한약자원식물을 수집 및 분류하여 약용작물로 재배하기 위한 기초자료로 활용하고자 이 지역의 한약자원 식물의 분류를 조사한 결과는 다음과 같았다. $\bullet$ 모후산에 분포되어 있는 한약자원 식물은 58과 230종으로 분류되었다. $\bullet$ 분류수종중 초본류는 질경이, 차조기, 쇠무릎, 우엉, 사삼, 반하, 하수오, 결명자, 용담초, 맥문동, 하고초, 산삼, 도라지, 둥글레, 참마, 칡, 대계등 17종과 대본류는 인동초, 참으아리, 방기, 목퉁, 엄나무, 구기자, 산수유, 밤나무, 매화, 인진호, 희첨, 지유, 초오등 13종이 한약재료로 많이 사용되는 것들이었다.