• 제목/요약/키워드: Later Life

검색결과 1,089건 처리시간 0.026초

Development of a Cost-benefit Model for the Management of Structural Risk on Oil Facilities in Mexico

  • Leon, David-De;Alfredo H-S. Ang
    • Computational Structural Engineering : An International Journal
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    • 제2권1호
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    • pp.19-23
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    • 2002
  • A reliability-based cost-benefit model for the risk management of oil platforms in the formulation of optimal decisions based on life-cycle consideration is proposed. The model is based on structural risk assessments and the integration of social issues and economics into the management decision process. Structural risks result from the platform's exposure to the random environmental loading associated with the offshore site where it is located. Several alternative designs of a typical platform are proposed and assessed from the cost-effectiveness viewpoint. This assessment is performed through the generation of cost/benefit relationships that are used, later on, to select the optimal design.

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Long Double-stranded RNA Induces Sequence-specific RNA Interference and Type I Interferon Responses in Rock Bream (Oplegnathus fasciatus)

  • Zenke, Kosuke;Kim, Ki-Hong
    • Fisheries and Aquatic Sciences
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    • 제13권1호
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    • pp.56-62
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    • 2010
  • To determine whether long double-stranded RNA (dsRNA) induces RNA interference and type I interferon (IFN) responses in fish, long dsRNAs encoding enhanced green fluorescent protein (EGFP), GFPuv, and polyinosinic-polycytidylic acid sequences were co-injected with an EGFP expressing plasmid, into rock bream (Oplegnathus fasciatus). We investigated the EGFP mRNA and protein levels, and the transcriptional responses of dsRNA-dependent protein kinase and Mx1 genes. Long dsRNAs were strong inducers of a type I IFN response in rock bream, resulting in nonspecific suppression of exogenous gene expression. Furthermore, sequence-specific knockdown of exogenous gene expression at the mRNA level was detected at an early phase (24 h). These results suggested that long dsRNA may inhibit exogenous gene expression through an early mRNA interference response and a later type I IFN response in fish.

홍화 첨가와 저장기간에 따른 유과의 품질 특성 (Quality Characteristics of Yukwa by Addition Safflower and Storage Period)

  • 박금순
    • 동아시아식생활학회지
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    • 제14권5호
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    • pp.463-471
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    • 2004
  • The objectives of this study were to investigate quality characteristics of Yukwa which containing 0, 1, 3, 5% of safflower chemical properties showed that degree of expansion of Yukwa were decreased as the amount of safflower increased, while fat absorption increased. Fatty acid of Yukwa were increased as the amount of safflower increased. Sensory properties showed that cripsness of Yukwa were significant difference(P<.001) in the Yukwa with Safflower. L-value decreased by the addition of safflower, while a-value and yellowness increased. The mechanical properties showed that hardness and brittleness was the highest in the Yukwa with 5% safflower. Later 4 weeks and 6 weeks of storage, 3% and 5% safflower containing Yukwa showed decrease peroxide value and acid vale. respectively.

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사상의학초본권(四象醫學草本卷)과 동의수세보원(東醫壽世保元)에 나타난 이제마(李濟馬)의 사상의학관(四象醫學觀)에 관한 비교고찰(比較考察) (A Comparative Study on the View of Lee Je-ma's Constitutional Medicine expressed Sasang ChobonGuen and Dongyi Suse Bowon)

  • 이재원;송일병
    • 사상체질의학회지
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    • 제11권2호
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    • pp.75-94
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    • 1999
  • Purpose: This studied by the comparative method the view of Lee Je-ma's Constitutional Medicine expressed Sasang ChobonGuen and Dongyi Suse Bowon. 2. Method: I studied the view of Lee Je-ma's Constitutional Medicine classified broadly 'General view of life' and 'Constitutional view of life expressed SangChonbonGuen and Dongyi Suse Bowon. 3. Results & Conclusion: Sasang ChobonGuen gathered 'Seongmoung-Ron', 'Sadan-Ron', 'Hwakchoong-Ron', 'Byeonjeong-Ron' and a part of 'Jangbu-Ron' of Dongyi Suse Bowon. It is insufficient the explanation of 'CheonGi', but the fundamental spirit is same. The study of Soyangin is done earlier, the studies of Soeumin, Taeumin, Taeyangin is done later.

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Testing Whether New Is Better Than Used of Specified Age Using Moments Inequalities

  • Ahmad, Ibrahim A.;Al-Wasel, Ibrahim A.
    • International Journal of Reliability and Applications
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    • 제3권1호
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    • pp.17-23
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    • 2002
  • The class of “new better than used of a specified age” is a large and practical class of life distributions. Its properties, applicability, and testing was discussed by Hollander, Park and Proschan (1986). Their test, while remaining the yardstick for this class, suffers from weak efficiency and weak power, especially for specified ages below the average age. Thus, it is beneficial to have an alternative testing procedure that would work better for early ages and still work well for later ages. This is exactly the subject of the current note. The test developed here is also simpler than that of Hollander, et. al. (1986).

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Screening of Functional Rhizopus stolonifer for Alcohol Fermentation and Production of High Quality Korean Traditional Rice Wine

  • Song, Jung-Hwa;Kim, Jae-Ho;Ahn, Byung-Hak;Lee, Jong-Soo
    • Mycobiology
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    • 제38권2호
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    • pp.122-127
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    • 2010
  • Different strains of mold were screened for the production of high quality Korean traditional rice wine with anti-hypertension and good acceptability. We isolated 867 nuruk mold strains and selected 24 for further study based on measurement of amylase activity. Among them, mold No. 17 showed high ethanol production upon fermentation with Saccharomyces cerevisiae as well as anti-hypertensive properties. The No. 17 strain was therefore selected as the functional mold and later identified as Rhizopus stolonifer based on molecular biological characteristics. Optimal fermentation conditions for the brewing of anti-hypertensive traditional rice wine comprised the addition of R. stolonifer No. 17 koji at a concentration of 35 sp/g and a fermentation period of 10 days at $25^{\circ}C$ using S. cerevisiae.

전기자동차용 Plastic Li-ion battery

  • 한규남;서현미;김재경;김용삼;신동엽;정복환;임홍섭;엄승욱;문성인
    • 한국전기화학회:학술대회논문집
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    • 한국전기화학회 2000년도 전지기술심포지움
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    • pp.51-62
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    • 2000
  • Large plastic Li-ion (PLI) cells (25 to 28-Ah) were fabricated for an EV application. The 28-Ah cells showed high specific energy (160 Wh/kg), high specific power (526 W/g), excellent round-trip energy efficiency $(92\%)$, and low self-discharge rate ($6\%$ in 30 days). A 25-Ah cell of an earlier design showed good cycle life of up to 750 cycles at $100\%$ DOD to $80\%$ of its initial capacity, while cycle life test of a 28-Ah cell of a later design is in progress. Preliminary safety tests were also carried out using 6-Ah cells of a similar electrode design giving very encouraging results for development of a safe hish-energy density PLI battery for EV application.

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『오운육기의학보감(五運六氣醫學寶鑑)』의 저자(著者) 조원희(趙元熙)에 관한 연구(硏究) (A Study on Cho Wonhui(趙元熙), the Author of Ounyukgi-Uihakbogam(五運六氣醫學寶鑑))

  • 윤창렬
    • 대한한의학원전학회지
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    • 제32권1호
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    • pp.49-59
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    • 2019
  • Objectives : Cho Wonhui published his book "Ounyukgi-Uihakbogam", in which Ungi was used for clinical purposes, but his life is hardly known. Conclusions & Conclusions : Cho Wonhui passed the Jinsa exam in 1894 and entered Seonggyungwan. Gojong recommended him to study medicine, and in 1907, he treated a person (later Taisho Emperor) who visited the Korea Empire and achieved his reputation. He was invited to Japan with this opportunity and received a degree from Meiji Emperor, a philosophical doctor of medicine. He passed the medical intern examination in 1923, and in 1938, he published the book "Ounyukgi-Uihakbogam". After 6 25, the Ceonundang oriental medicine clinic was opened in Busan and patients were treated. In 1963, he died at the age of 90.: This study met Cho Wonhui's descendants and talked about the life of Cho Wonhui and comprehensively summarized the related data.

Microbial Colonization at Early Life Promotes the Development of Diet-Induced CD8αβ Intraepithelial T Cells

  • Jung, Jisun;Surh, Charles D.;Lee, You Jeong
    • Molecules and Cells
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    • 제42권4호
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    • pp.313-320
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    • 2019
  • Intraepithelial lymphocytes (IELs) develop through the continuous interaction with intestinal antigens such as commensal microbiome and diet. However, their respective roles and mutual interactions in the development of IELs are largely unknown. Here, we showed that dietary antigens regulate the development of the majority of $CD8{\alpha}{\beta}$ IELs in the small intestine and the absence of commensal microbiota particularly during the weaning period, delay the development of IELs. When we tested specific dietary components, such as wheat or combined corn, soybean and yeast, they were dependent on commensal bacteria for the timely development of diet-induced $CD8{\alpha}{\beta}$ IELs. In addition, supplementation of intestinal antigens later in life was inefficient for the full induction of $CD8{\alpha}{\beta}$ IELs. Overall, our findings suggest that early exposure to commensal bacteria is important for the proper development of dietary antigen-dependent immune repertoire in the gut.

Spontaneous intraspinal and intracranial subdural hematoma in a highly active antiretroviral therapy-naïve-patient with HIV

  • Hyun Jung Lee;Jeong Rae Yoo
    • Journal of Medicine and Life Science
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    • 제21권3호
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    • pp.106-111
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    • 2024
  • Spontaneous intraspinal and intracranial subdural hematomas (SDHs) are rare, potentially life-threatening complications. We present the case of a 38-yearold highly active antiretroviral therapy-naïve human immunodeficiency virus (HIV)-positive patient who developed simultaneous intraspinal and intracranial SDHs without hemostatic abnormalities. The patient presented with acute lower limb weakness and back pain, and later developed neurological symptoms, including diplopia and incontinence. This case highlights the importance of considering SDHs in HIV-positive patients presenting with neurological symptoms, and underscores the need for prompt diagnosis and multidisciplinary management.