• 한국작물학회지
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• 제55권3호
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• pp.200-206
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• 2010

Banaba, Lagerstroemia speciosa (L.) Pers. (Lythraceae) is a tree that grows in the tropic islands of the Pacific. This plants are used for medical purposes in the world. The components of L. speciosa were analyzed for the contents according to growing stages at leaves. The distributions of the corosolic acid ($2{\alpha}$, $3{\beta}$-dihydroxyurs-12-en-28-oic acid), phytol, campestrol, and vitamin E were rich among samples in this study. These were contained much fatty acids. The mean content of palmitic acid was from 2.4% across all growing stages, varying from 2.15% for young leaves with the lowest content and 2.86% for fallen leaves with the highest content. Oleic acid, linoleic acid, and linolenic acid were contained nearly mean 2.0% in all leaves of banaba. Our results have shown that the phytochemical profile of young L. speciosa leaves differs quite radically from that of old L. speciosa leaves. In addition, these subdividing results according to plant growth should allow future researches to conduct targeted experimental studies and use of particular medical components of interest, examining chemical variation on the inter-developmental levels.

• Advances in Traditional Medicine
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• 제9권3호
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• pp.225-231
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• 2009

The present study deals with the amelioration by Lagerstroemia speciosa Linn. leaf extract against hepatotoxicity induced by carbon tetrachloride ($CCl_4$), which was evaluated in terms of serum marker enzymes like serum glutamate pyruvate transaminase, serum glutamate oxaloacetate transaminase, alkaline phosphatase, serum total bilirubin, total protein levels along with concomitant hepatic and antioxidants like superoxide dismutase, catalase, glutathione, glutathione peroxidase and lipid peroxidation enzymes were monitored. These biochemical parameters altered by the single dose level of $CCl_4$ (0.75 ml/kg body weight, i.p). Pre treatment with L. speciosa prior to the administration of $CCl_4$, at the doses of 50 and 250 mg/kg. body weight/day, p.o. for 7 days, significantly restored all the serum and liver tissue parameters near to the normal levels, respectively. Silymarin was used as a reference standard, prior to the administration of $CCl_4$ to rats. These findings indicate the protective potential of L. speciosa against hepato toxicity which possibly involve mechanism related to its ability of selective inhibitors of (reactive oxygen species like antioxidants brought about significant inhibition of TBARS suggesting possible involvement of $O_2{\cdot}-$, $HO_2{\cdot}$, and ${\cdot}OH$. In conclusion, the amelioration may be attributed to the synergistic effects of its constituents rather than to any single factor as the leaves are rich in tannins, sterols, flavonoids, saponins etc.

• International Journal of Industrial Entomology and Biomaterials
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• 제30권2호
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• pp.58-63
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• 2015

An experimental rearing of tropical tasar silkworm, Antheraea mylitta Drury was conducted to study silkworm-food plant-interaction and thereby to search for an alternate silkworm food plant. The silkworm-food-plant-interaction was studied with six different food plant species viz. Terminalia tomentosa, Terminalia arjuna, Terminalia belerica, Terminalia chebula of Combretaceae family and Lagerstroemia speciosa, Lagerstroemia parviflora of Lythraceae family. The rearing performance of silkworm on Lagerstroemia speciosa in terms of cocoons per DFL and silk ratio was found comparable with Terminalia tomentosa and Termonalia arjuna, the primary tasar silkworm food plant species. These three plant species also possessed better results in terms of physiological (leaf moisture content and net photosynthesis rate) and biochemical (Chlorophyll, protein, carbohydrate and crude fibre contents) characteristics to support silkworm rearing than Terminalia belerica, Terminalia chebula and Lagerstroemia parviflora. The correlation study between silkworm rearing performance and food plant's constituents indicates commercial perspective of Lagerstroemia speciosa as an alternate food plant for tasar silkworm rearing.

• 생명과학회지
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• 제19권1호
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• pp.40-45
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• 2009

구아바(Psidium guajava L.)와 바나바(Lagerstroemia speciosa L.)는 항당뇨 효과를 갖는 대표적인 약용식물로 알려져 있다. 이들 식물은 다양한 폴리페놀(polyphenol) 성분을 함유하며 당뇨병의 치료에 효과적으로 작용한다. 따라서 본 연구는 이들 추출물을 streptozotocin (STZ)으로 당뇨를 유발한 실험쥐에 섭취시켜 항당뇨 효과를 상호 비교하였다. STZ으로 당뇨를 유발한 실험쥐에 구아바 및 바나바 잎 추출물을 섭취시킨 결과 당뇨쥐에 비해 혈당은 약 19-32%, 총콜레스테롤(total cholesterol)은 약 24-46%, 중성지방(triglyceride)은 22-67% 그리고 유리지방산(free fatty acid) 은 49-71% 감소하였고 또한 인슐린 분비와 췌장에 존재하는 베타세포의 회복도 증가되었다. 한편 구아바 추출물의 섭취가 바나바 추출물의 섭취에 비해 항당뇨 효과가 더 높았는데 그 이유는 바나바 잎에 포함된 친수성 폴리페놀(polyphenol) 성분이 에탄올 추출과정에서 대부분 추출되지 않았고 또한 추출된 코로소릭산(corosolic acid) 은 지금까지 알려진 것과는 달리 항당뇨 활성이 낮았기 때문이다.

• 한국응용곤충학회지
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• 제55권2호
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• pp.171-175
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• 2016

Tinocallis Matsumura 속은 전세계 19종이 포함되는 비교적 큰 속이다. 본 연구에서는 최근 라오스에서 바나바 (부채꽃과: 배롱나무속)에 심각한 피해를 주는 알락진딧물 일종, Tinocallis himalayensis Ghosh, Ghosh & Raychaudhuri, 1971를 처음으로 발견하여 보고한다. 유시형 처녀생식세대의 암컷 형태, 생태 및 피해 사진을 함께 제시하였다.

• 통합자연과학논문집
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• 제5권2호
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• pp.100-106
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• 2012

Herbal medicines have been used since the dawn of civilization to maintain health and to treat diseases. Diabetes mellitus is one of the leading cause of death in many developed countries. The incidence of diabetes is increasing at an alarming rate in India. It was estimated that India which had 19.4 million diabetes in 1995 is expected to register a near threefold increase by. Many plants reported to be useful for the treatment of diabetes mellitus in ayurvedic medicine, are being tested for their hypoglycemic activity in experimental animals Lagerstroemia flos- reginae is one such plant commonly found as shade trees in Kerala. In Ayurveda both root and leaves are used in the treatment of diabetes. The main objective of this study was to assess the antidiabetic effect of the alcohol extracted leaves of Lagerstroemia flos- reginae in alloxan induced diabetic rats in terms of controlling blood glucose level, lipid profile, bilirubin, uric acid in serum and lipid peroxides and glutathione in the liver of the experimental animals. The present study has been undertaken to observe the protective effect of the active constituents of Lagerstroemia flos- reginae leaf extracts against alloxan induced diabetes in experimental animal model. The activity of the active constituents was compared with Daonil -a standard drug.

• 생명과학회지
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• 제18권9호
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• pp.1305-1311
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• 2008

본 연구는 바나바 잎 추출 용매에 따른 항당뇨 효과에 관한 것으로 세포 독성 실험을 통하여 인체에 대한 독성이 없음을 확인하였고 $\beta$-cell 인슐린 분비 실험을 통하여 항당뇨 효과를 알아보았다. 또한 당뇨 유발쥐를 이용한 인슐린 분비 실험, 체중변화 측정, 혈중 및 혈청의 glucose 농도, 총콜레스테롤 수치, HDL-cholesterol 농도, triglyceride 농도, free fatty acid 농도, langerhans islet에서의 인슐린 분비 의 확인을 통해 혈당조절 효과를 비교하였다. 물 혹은 에탄올을 단독으로 이용하여 추출한 추출물이나 70%, 90% 에탄올로 추출한 추출물 보다 열수로 먼저 추출한 후 에탄올로 다시 추출하여 혼합안 추출물이 항당뇨 효과가 더 뛰어남을 알 수 있었다. 이는 친수성(hydrophilic) 유효성분들과 소수성(hydrophobic) 유효성분들의 추출 유무나 함량에 의한 것이다. 특히, 많은 문헌에 언급된 코로소린산이라는 단일 성분(unique)에 의한 항당뇨 효과라기보다는 친수성 및 소수성 폴리페놀 및 항산화성분과 같은 유효성분들이 조합되어(mixture) 항당뇨 효과에 영향을 미치는 것으로 사료된다.

• 생명과학회지
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• 제19권3호
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• pp.334-342
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• 2009

본 연구는 streptozotocin (STZ)으로 당뇨를 유발한 실험쥐에 대한 Psidium guajava L. 잎(Pg), Lagerstroemia speciosa L. 잎(Ls) 추출물 그리고 혼합물 A (Pg, Ls, Morus indica L. 잎 추출물, Pinus densiflora needles 추출물, Acanthopanax senticosus M. roots 추출물)의 효과를 조사하였다. 4주간 streptozotocin (STZ)으로 당뇨를 유발한 실험쥐에 이들 추출물을 섭취시킨 결과 Pg, Ls 그리고 혼합물 A의 섭취는 당뇨 대조군에 비해 혈당을 각각 20%, 14% 그리고 24% 감소시켰다. 또한 이들 추출물의 섭취는 총 콜레스트롤, 중성지방, 유리지방산을 감소시켰고 인슐린과 HDL-콜레스트롤을 효과적으로 증가시켰다. 결론적으로 혼합물 A는 Pg와 Ls 추출물에 비해 혈당 및 지질 감소, 인슐린 증가 효과 그리고 기능적으로 손상된 베타세포의 회복이 더 높은 것으로 나타났다. 따라서 혼합물 A는 개별적으로 사용한 Pg와 Ls 추출물에 비해 더욱 유익한 상승효과를 발휘하는 것으로 증명되었다.

• International Journal of Industrial Entomology and Biomaterials
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• 제30권2호
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• pp.31-39
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• 2015

Antheraea mylitta Drury (Lepidoptera: Saturniidae) is a commercial silk producing forest insect of India, but it has never been experimented in Uttarakhand state in spite of the huge availability of its forestry host plants. This is the first study on A. mylitta in Uttarakhand. The goal of this study is to introduce forest based commercial rearing of A. mylitta, in tropical forest areas of Uttarakhand to reduce poverty among forest dependent people. In current study, we assessed the effect of seven forest tree species, rearing seasons, and their interactions on cocoon productivity of Daba (bivoltine) ecorace of A. mylitta in the New Forest of FRI, Dehra Dun during 2012 and 2013 and collected the data that was analysed by two-way completely randomized block factorial design. Post HOC Tukey's HSD test was carried out to compare the homogeneous pairs of means. We also carried out Evaluation Index analysis to rank the tested forestry host plants for better growth and development of A. mylitta under the climatic condition of Uttarakhand. Analysis of variance indicated that cocoon yield of A. mylitta differed significantly between rearing seasons (DF=1, F=88.24, p<0.05) and host plants (DF 6, F= 368.63, p<0.05); however, their interactions were found insignificant (DF=6, F=0.99, p>0.05). In first rearing season of July-August, there was higher cocoon yield than the second season of September-November. Results indicated that Terminalia alata fed larvae showed significantly higher cocoon yield (164.11 cocoons/300 larvae); followed by, T. tomentosa (148.89 cocoons), T. arjuna (140.00 cocoons) and Lagerstroemia speciosa (129.47 cocoons) fed larvae. Whereas, Lagerstroemia tomentosa fed larvae that was used by the first time in India, showed lowest cocoon yield (48.81 cocoons), followed by T. chebula (72.53 cocoons) fed larvae. Cocoon yield of T. tomentosa and T. arjuna fed larvae of A. mylitta did not differ significantly with each other.

• BMB Reports
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• 제49권5호
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• pp.276-281
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• 2016

Corosolic acid (CA), a triterpenoid compound isolated from Lagerstroemia speciosa L. (Banaba) leaves, exerts anti-inflammatory effects by regulating phosphorylation of interleukin receptor- associated kinase (IRAK)-2 via the NF-κB cascade. However, the protective effect of CA against endotoxic shock has not been reported. LPS (200 ng/mL, 30 min) induced phosphorylation of IRAK-1 and treatment with CA (10 μM) significantly attenuated this effect. In addition, CA also reduced protein levels of NLRP3 and ASC which are the main components of the inflammasome in BMDMs. LPS-induced inflammasome assembly through activation of IRAK-1 was down-regulated by CA challenge. Treatment with Bay11-7082, an inhibitor of IκB-α, had no effect on CA-mediated inhibition of IRAK-1 activation, indicating that CA-mediated attenuation of IRAK-1 phosphorylation was independent of NF-κB signaling. These results demonstrate that CA ameliorates acute inflammation in mouse BMDMs and CA may be useful as a pharmacological agent to prevent acute inflammation.