• 제목/요약/키워드: Laboratory chamber tests

검색결과 56건 처리시간 0.027초

Stability Test and Quantitative and Qualitative Analyses of the Amino Acids in Pharmacopuncture Extracted from Scolopendra subspinipes mutilans

  • Cho, GyeYoon;Han, KyuChul;Yoon, JinYoung
    • 대한약침학회지
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    • 제18권1호
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    • pp.44-55
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    • 2015
  • Objectives: Scolopendra subspinipes mutilans (S. subspinipes mutilans) is known as a traditional medicine and includes various amino acids, peptides and proteins. The amino acids in the pharmacopuncture extracted from S. subspinipes mutilans by using derivatization methods were analyzed quantitatively and qualitatively by using high performance liquid chromatography (HPLC) over a 12 month period to confirm its stability. Methods: Amino acids of pharmacopuncture extracted from S. subspinipes mutilans were derived by using O-phthaldialdehyde (OPA) & 9-fluorenyl methoxy carbonyl chloride (FMOC) reagent and were analyzed using HPLC. The amino acids were detected by using a diode array detector (DAD) and a fluorescence detector (FLD) to compare a mixed amino acid standard (STD) to the pharmacopuncture from centipedes. The stability tests on the pharmacopuncture from centipedes were done using HPLC for three conditions: a room temperature test chamber, an acceleration test chamber, and a cold test chamber. Results: The pharmacopuncture from centipedes was prepared by using the method of the Korean Pharmacopuncture Institute (KPI) and through quantitative analyses was shown to contain 9 amino acids of the 16 amino acids in the mixed amino acid STD. The amounts of the amino acids in the pharmacopuncture from centipedes were 34.37 ppm of aspartate, 123.72 ppm of arginine, 170.63 ppm of alanine, 59.55 ppm of leucine and 57 ppm of lysine. The relative standard deviation (RSD %) results for the pharmacopuncture from centipedes had a maximum value of 14.95% and minimum value of 1.795% on the room temperature test chamber, the acceleration test chamber and the cold test chamber stability tests. Conclusion: Stability tests on and quantitative and qualitative analyses of the amino acids in the pharmacopuncture extracted from centipedes by using derivatization methods were performed by using HPLC. Through research, we hope to determine the relationship between time and the concentrations of the amino acids in the pharmacopuncture extracted from centipedes.

순환골재 다공질 콘크리트말뚝 공법에 대한 실내모형실험 (Experimental Study on Recycled-Aggregate Porous Concrete Pile Method)

  • 유승경;이창민;김세원;최항석
    • 한국지반신소재학회논문집
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    • 제7권2호
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    • pp.23-29
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    • 2008
  • 본 연구의 목적은 연약지반개량을 위한 다짐말뚝공법의 재료로써 건설폐기물에서 선별 처리된 순환골재의 적용성을 평가함과 동시에 기존 다짐말뚝공법들의 단점을 보완하는 새로운 공법을 개발하는 데 있다. 본 논문에서는 순환골재 다공질 콘크리트말뚝에 의한 지반개량효과를 분석하기 위하여 실내모형실험을 수행하였다. 실험결과로부터 개량된 복합지반의 침하량과 과잉간 극수압 및 연직응력증분의 시간에 따른 변화 특성과 복합지반의 거동 특성을 분석하였다.

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순환골재 다공질 콘크리트말뚝에 의한 압밀촉진효과에 관한 고찰 (A Study on the Effect of Promoting Consolidation by Recycled-Aggregate Porous Concrete Pile)

  • 유승경
    • 한국지반신소재학회논문집
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    • 제8권4호
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    • pp.35-40
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    • 2009
  • 본 논문에서는 순환골재 다공질 콘크리트말뚝(RAPP : Recycled-Aggregate Porous Concrete Pile)에 의한 압밀촉진효과를 파악하기 위하여 일련의 실내모형실험을 수행하였다. 본 연구에서 얻어진 실험 결과를 동일한 조건에서 수행한 모래다짐말뚝과 쇄석다짐말뚝에 대한 기존의 실험결과(유승경, 2009)와 비교하여 RAPP로 개량된 복합지반의 시간에 따른 침하량의 변화 특성과 압밀시간에 대하여 비교, 분석하였다. 또한 일련의 수치해석을 수행하여 실내모형실험 결과를 평가하였다. 분석 결과로부터 RAPP에 의한 일차압밀과 이차압밀에 대한 침하저감효과가 타 공법에 비해 탁월함을 알 수 있었으며 압밀 종료시간도 상대적으로 빠르게 나타나 RAPP에 의한 압밀촉진효과가 우수함을 입증할 수 있었다.

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Large Calibration Chamber의 개발 (Development of Large Calibration Chamber System)

  • 정충열;김태준;김대규;이우진
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2002년도 봄 학술발표회 논문집
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    • pp.673-678
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    • 2002
  • Laboratory calibration chamber tests for cone penetrometers, pressuremeters and dilatometers in cohesionless soil specimens have been conducted by numerous researchers. However, there have been only few applications to compacted or preconsolidated cohesive soils. Therefore, for the first time, Calibration Chamber System was developed in Korea University. This can be attributed to the extremely time consuming and laborious process involved in the preparation of large cohesive soil specimens in addition to other complexities involving instrumentation for pore pressure monitoring and the need for maintaing saturation by back pressure. Chamber System with similar principle as LSU Chamber System was made of more strengthen and complementary form by increasing system diameter(1.2m), carrying out 1st and 2nd consolidation process in one system for smooth and safe work, accurate Data Aquisition.

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고압산소챔버 중재가 알코올에 의한 산화적 스트레스 및 숙취 해소에 미치는 영향 (Effects of Hyperbaric Oxygen Intervention on Alcohol-Induced Oxidative Stress and Hangover in Hyperbaric Oxygen Chamber)

  • 권혁찬;박순원;조현정;강지현;이현주;태기식
    • 대한의용생체공학회:의공학회지
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    • 제39권5호
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    • pp.175-182
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    • 2018
  • The purpose of this study is to evaluate the reliability and effectiveness of hyperbaric oxygen chamber on alcohol-induced oxidative stress and hangover. In order to evaluate them, 20 healthy adults were tested for blood and hangover stress tests. When an exponential change was examined after 3 interventions (hangover drink, hyperbaric oxygen chamber, and normal chamber as placebo effect) of 1 hour, the heart rate of subjects experiencing a hyperbaric oxygen chamber showed a statistically significant decrease (p < 0.001). The tests of blood alcohol concentration (BAC) as for exquisite hematology analysis, glucose, creatinine, and AST (aspartate aminotransferase) as well as ALT (alanine aminotransferase) used as liver-damage indicator show that the hyperbaric chamber has the effective effect. In the test of lactic acid, CRP (c-reactive protein), cortisol, and creatinine, the hyperbaric chamber shows much more excellent effect than the hangover drink and normal chamber as control groups. Further studies on hyperbaric oxygen chamber intervention including this study could be very helpful for improving lives of both the patients and healthy people.

OWC형 파력발전 공기챔버의 공기감쇠력 실험연구 (An Experimental Study of Pneumatic Damping at the Air Chamber for OWC type Wave Energy Device)

  • 최학선;류재문;홍석원;김진하
    • 한국해양공학회:학술대회논문집
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    • 한국해양공학회 2004년도 학술대회지
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    • pp.138-144
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    • 2004
  • Pneumatic damping through a orifice type duct for OWC type wave energy device is studied experimentally. Forced oscillation tests are made to measure chamber pressure and velocity of air flaw through orifice. Pneumatic damping coefficient are deducted from the experimental research, and discussion are made far the influence of frequency, heave amplitude, and orifice size. Finally two formula are proposed for the estimation of non-dimensional pneumatic damping coefficient by regression analysis. The proposed formula proves to be a reliable method far practical application.

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OWC형 파력발전 공기챔버의 공기감쇠력 실험 연구 (An Experimental Study of Pneumatic Damping at the Air Chamber for an OWC-type Wave Energy Device)

  • 최학선;홍석원;김진하;류재문
    • 한국해양공학회지
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    • 제18권4호
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    • pp.8-14
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    • 2004
  • Pneumatic damping through an orifice-type duct for an OWC-type wave energy device is studied experimentally. Forced oscillation tests are used to measure chamber pressure and velocity of air-flow through an orifice. Pneumatic damping coefficients are deducted from the experimental research, and the influence of frequency, heave amplitude, and orifice size are discussed. Finally, two formulas are proposed for the estimation of non-dimensional pneumatic damping coefficient by regression analysis. The proposed formula proves to be a reliable method for practical application.

순환골재 다공질 콘크리트말뚝(RAPP)에 의해 보강된 복합지반의 거동 특성 (Characterization of Composite Ground Reinforced with Recycled-Aggregate Porous Concrete Pile (RAPP))

  • 유승경;김세원;이철호;최항석
    • 한국지반공학회논문집
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    • 제25권11호
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    • pp.117-130
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    • 2009
  • 본 논문에서는 순환골재 다공질 콘크리트말뚝(Recycled-Aggregate Porous Concrete Pile, RAPP)에 의한 지반개량효과를 파악하기 위하여 기존에 수행된 실내모형실험(유승경 등, 2008(a)) 결과를 분석하였다. 본 연구에서 얻어진 실험 결과를 동일한 조건에서 수행한 SCP 실험 결과와 비교하여 RAPP로 개량된 복합지반의 침하량과 과잉간극수압 및 연직응력증분의 시간에 따른 변화 특성과 복합지반의 거동 특성을 비교, 분석하였다. 또한, 수치해석을 통하여 실내모형실험 결과를 평가하였다. 그 결과, RAPP로 개량된 복합지반에서 하중재하시 응력분담이 뚜렷이 발생하여 침하저감 효과가 크게 얻어졌다. 또한, 복합지반의 압밀도를 산정하여 분석한 결과, RAPP는 배수재로서의 기능을 충분히 발휘하여 압밀촉진 효과가 있음을 확인할 수 있었다.

실내모형시험을 통한 도로함몰 매커니즘에 대한 기초적 연구 (Basic Study on Mechanism of Cave-in in Road through Laboratory Model Tests)

  • 권기철;김상록;홍석우
    • 한국도로학회논문집
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    • 제18권5호
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    • pp.11-19
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    • 2016
  • PURPOSES : This study identifies the causes and the mechanism of the occurrence of underground cavities. METHODS : A case study on cave-in and a series of model tests with a small soil chamber were conducted. RESULTS : A hypothesis about the mechanism of the cave-in in road was established, and the basic influencing factors on underground cavity expansion were identified. CONCLUSIONS : It was found that the characteristics of shear strength of soil and direction of water flow had a larger influence on cavity formation and expansion than the characteristics of internal erosion. In addition, large cavities suddenly expanded when cavities were caused owing to breakage of buried sewer pipe.

모형챔버시험을 이용한 사질토 지반의 경량포장체용 기초의 하중전달 특성 (Load Transfer Characteristics of Pile Foundation for Lightweight Pavement in Sand Soil using Laboratory Chamber Test)

  • 신광호;황철비;전상렬;이관호
    • 한국산학기술학회논문지
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    • 제15권7호
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    • pp.4588-4594
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    • 2014
  • 본 연구에서는 연약지반에서의 경량콘크리트포장을 적용할 때의 안전성 평가를 위해 실제 포장체 사이즈의 1/30으로 축소한 모형을 이용하여 모래지반에서 실험을 실시하였다. 모형토조를 이용하여 지반을 조성하였고, 표준 말뚝재하시험(완속재하시험방법)을 이용하였다. 수직하중이 적용되는 말뚝기초의 슬래브의 중심에서 가까운 순으로 Case A, Case B, Case C로 구분하였고, 각각의 말뚝의 간격은 8cm로 하였다. 말뚝기초 모형시험결과 사질토지반에서 수직하중을 1.5kg에서 12kg로 증가시킬 때 포장체가 전체적으로 침하하였고, 최대 침하량은 0.4mm로 측정되었다. Case A의 경우 압축력을 받는 것으로 나타났으며, Case B는 수직하중이 증가함에 따라 말뚝에 압축력과 함께 인장력도 같이 받는 것으로 보이며, Case C는 하중단계가 증가할수록 인장변형이 증가하는 경향을 나타내었다.