• Title/Summary/Keyword: Laboratory chamber tests

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Stability Test and Quantitative and Qualitative Analyses of the Amino Acids in Pharmacopuncture Extracted from Scolopendra subspinipes mutilans

  • Cho, GyeYoon;Han, KyuChul;Yoon, JinYoung
    • Journal of Pharmacopuncture
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    • v.18 no.1
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    • pp.44-55
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    • 2015
  • Objectives: Scolopendra subspinipes mutilans (S. subspinipes mutilans) is known as a traditional medicine and includes various amino acids, peptides and proteins. The amino acids in the pharmacopuncture extracted from S. subspinipes mutilans by using derivatization methods were analyzed quantitatively and qualitatively by using high performance liquid chromatography (HPLC) over a 12 month period to confirm its stability. Methods: Amino acids of pharmacopuncture extracted from S. subspinipes mutilans were derived by using O-phthaldialdehyde (OPA) & 9-fluorenyl methoxy carbonyl chloride (FMOC) reagent and were analyzed using HPLC. The amino acids were detected by using a diode array detector (DAD) and a fluorescence detector (FLD) to compare a mixed amino acid standard (STD) to the pharmacopuncture from centipedes. The stability tests on the pharmacopuncture from centipedes were done using HPLC for three conditions: a room temperature test chamber, an acceleration test chamber, and a cold test chamber. Results: The pharmacopuncture from centipedes was prepared by using the method of the Korean Pharmacopuncture Institute (KPI) and through quantitative analyses was shown to contain 9 amino acids of the 16 amino acids in the mixed amino acid STD. The amounts of the amino acids in the pharmacopuncture from centipedes were 34.37 ppm of aspartate, 123.72 ppm of arginine, 170.63 ppm of alanine, 59.55 ppm of leucine and 57 ppm of lysine. The relative standard deviation (RSD %) results for the pharmacopuncture from centipedes had a maximum value of 14.95% and minimum value of 1.795% on the room temperature test chamber, the acceleration test chamber and the cold test chamber stability tests. Conclusion: Stability tests on and quantitative and qualitative analyses of the amino acids in the pharmacopuncture extracted from centipedes by using derivatization methods were performed by using HPLC. Through research, we hope to determine the relationship between time and the concentrations of the amino acids in the pharmacopuncture extracted from centipedes.

Experimental Study on Recycled-Aggregate Porous Concrete Pile Method (순환골재 다공질 콘크리트말뚝 공법에 대한 실내모형실험)

  • You, Seung-Kyong;Lee, Chang-Min;Kim, Se-Won;Choi, Hang-Seok
    • Journal of the Korean Geosynthetics Society
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    • v.7 no.2
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    • pp.23-29
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    • 2008
  • The purpose of this research is to assess the application of recycled-aggregate that is gained from construction wastes as the material of compaction pile method. At the same time, the development of the new technique rectifies defects of the existing compaction pile method for soft ground improvement. In this research, laboratory chamber tests were carried out analyzing the effect of the soft ground improvement by porous concrete pile using recycled aggregate. Through the results of the laboratory chamber tests, the variations of settlement, excess pore pressure, and increment of the vertical stress with time and the behavior of the composite ground were elucidated.

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A Study on the Effect of Promoting Consolidation by Recycled-Aggregate Porous Concrete Pile (순환골재 다공질 콘크리트말뚝에 의한 압밀촉진효과에 관한 고찰)

  • You, Seung-Kyong
    • Journal of the Korean Geosynthetics Society
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    • v.8 no.4
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    • pp.35-40
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    • 2009
  • In this paper, a series of laboratory chamber tests was carried out to evaluate promoting consolidation of a porous concrete pile fabricated with recycled aggregates (RAPP) method for soft ground improvement. Performing the laboratory chamber tests for the RAPP, characteristics of the surface settlement with time and the consolidation time were compared with those of SCP and GCP provided by You (2009) under the same experimental condition. In addition, the experimental results were compared with the numerical analysis in this study. As a test result, the effects for settlement reduction in both the primary and the secondary consolidation and promoting consolidation by RAPP were prominent comparatively.

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Development of Large Calibration Chamber System (Large Calibration Chamber의 개발)

  • 정충열;김태준;김대규;이우진
    • Proceedings of the Korean Geotechical Society Conference
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    • 2002.03a
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    • pp.673-678
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    • 2002
  • Laboratory calibration chamber tests for cone penetrometers, pressuremeters and dilatometers in cohesionless soil specimens have been conducted by numerous researchers. However, there have been only few applications to compacted or preconsolidated cohesive soils. Therefore, for the first time, Calibration Chamber System was developed in Korea University. This can be attributed to the extremely time consuming and laborious process involved in the preparation of large cohesive soil specimens in addition to other complexities involving instrumentation for pore pressure monitoring and the need for maintaing saturation by back pressure. Chamber System with similar principle as LSU Chamber System was made of more strengthen and complementary form by increasing system diameter(1.2m), carrying out 1st and 2nd consolidation process in one system for smooth and safe work, accurate Data Aquisition.

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Effects of Hyperbaric Oxygen Intervention on Alcohol-Induced Oxidative Stress and Hangover in Hyperbaric Oxygen Chamber (고압산소챔버 중재가 알코올에 의한 산화적 스트레스 및 숙취 해소에 미치는 영향)

  • Kwon, Hyeok Chan;Park, Soon Won;Cho, Hyun Jeong;Kang, Ji Hyun;Lee, Hyun Ju;Tae, Ki Sik
    • Journal of Biomedical Engineering Research
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    • v.39 no.5
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    • pp.175-182
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    • 2018
  • The purpose of this study is to evaluate the reliability and effectiveness of hyperbaric oxygen chamber on alcohol-induced oxidative stress and hangover. In order to evaluate them, 20 healthy adults were tested for blood and hangover stress tests. When an exponential change was examined after 3 interventions (hangover drink, hyperbaric oxygen chamber, and normal chamber as placebo effect) of 1 hour, the heart rate of subjects experiencing a hyperbaric oxygen chamber showed a statistically significant decrease (p < 0.001). The tests of blood alcohol concentration (BAC) as for exquisite hematology analysis, glucose, creatinine, and AST (aspartate aminotransferase) as well as ALT (alanine aminotransferase) used as liver-damage indicator show that the hyperbaric chamber has the effective effect. In the test of lactic acid, CRP (c-reactive protein), cortisol, and creatinine, the hyperbaric chamber shows much more excellent effect than the hangover drink and normal chamber as control groups. Further studies on hyperbaric oxygen chamber intervention including this study could be very helpful for improving lives of both the patients and healthy people.

An Experimental Study of Pneumatic Damping at the Air Chamber for OWC type Wave Energy Device (OWC형 파력발전 공기챔버의 공기감쇠력 실험연구)

  • CHOI Hark-Sun;LEW Jae-Moon;HONG Seok-Won;KIM Jin-Ha
    • Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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    • 2004.05a
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    • pp.138-144
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    • 2004
  • Pneumatic damping through a orifice type duct for OWC type wave energy device is studied experimentally. Forced oscillation tests are made to measure chamber pressure and velocity of air flaw through orifice. Pneumatic damping coefficient are deducted from the experimental research, and discussion are made far the influence of frequency, heave amplitude, and orifice size. Finally two formula are proposed for the estimation of non-dimensional pneumatic damping coefficient by regression analysis. The proposed formula proves to be a reliable method far practical application.

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An Experimental Study of Pneumatic Damping at the Air Chamber for an OWC-type Wave Energy Device (OWC형 파력발전 공기챔버의 공기감쇠력 실험 연구)

  • CHOI HARK-SUN;HONG SEOK-WON;KlM JIN-HA;LEW JAE-MOON
    • Journal of Ocean Engineering and Technology
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    • v.18 no.4 s.59
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    • pp.8-14
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    • 2004
  • Pneumatic damping through an orifice-type duct for an OWC-type wave energy device is studied experimentally. Forced oscillation tests are used to measure chamber pressure and velocity of air-flow through an orifice. Pneumatic damping coefficients are deducted from the experimental research, and the influence of frequency, heave amplitude, and orifice size are discussed. Finally, two formulas are proposed for the estimation of non-dimensional pneumatic damping coefficient by regression analysis. The proposed formula proves to be a reliable method for practical application.

Characterization of Composite Ground Reinforced with Recycled-Aggregate Porous Concrete Pile (RAPP) (순환골재 다공질 콘크리트말뚝(RAPP)에 의해 보강된 복합지반의 거동 특성)

  • You, Seung-Kyong;Kim, Se-Won;Lee, Chul-Ho;Choi, Hang-Seok
    • Journal of the Korean Geotechnical Society
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    • v.25 no.11
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    • pp.117-130
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    • 2009
  • In this paper, a series of laboratory chamber tests were carried out to evaluate the applicability of a porous concrete pile fabricated with recycled aggregates (RAPP) for the soft ground improvement. While performing the laboratory chamber tests for the RAPP, the surface settlement, excess pore pressure and vertical stress distribution with time were compared with those of SCP provided by You (2003) under the same experimental condition. In addition, the experimental results were compared with the numerical simulation using ABAQUS in this study. The results show that the settlement reduction is significantly enhanced due to the stress-sharing mechanism between the RAPP and soil formation by stress concentration on the RAPP. Furthermore, the comparison of consolidation rate shows that the RAPP can accelerate consolidation as well, which behaves as a vertical drain.

Basic Study on Mechanism of Cave-in in Road through Laboratory Model Tests (실내모형시험을 통한 도로함몰 매커니즘에 대한 기초적 연구)

  • Kweon, Gichul;Kim, Sanglok;Hong, Seokwoo
    • International Journal of Highway Engineering
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    • v.18 no.5
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    • pp.11-19
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    • 2016
  • PURPOSES : This study identifies the causes and the mechanism of the occurrence of underground cavities. METHODS : A case study on cave-in and a series of model tests with a small soil chamber were conducted. RESULTS : A hypothesis about the mechanism of the cave-in in road was established, and the basic influencing factors on underground cavity expansion were identified. CONCLUSIONS : It was found that the characteristics of shear strength of soil and direction of water flow had a larger influence on cavity formation and expansion than the characteristics of internal erosion. In addition, large cavities suddenly expanded when cavities were caused owing to breakage of buried sewer pipe.

Load Transfer Characteristics of Pile Foundation for Lightweight Pavement in Sand Soil using Laboratory Chamber Test (모형챔버시험을 이용한 사질토 지반의 경량포장체용 기초의 하중전달 특성)

  • Shin, Kwang-Ho;Hwang, Cheol-Bi;Jeon, Sang-Ryeol;Lee, Kwan-Ho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.7
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    • pp.4588-4594
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    • 2014
  • In this study, small scaled (1/30) laboratory chamber tests of the pile foundation for a lightweight concrete pavement system were carried out to evaluate the safety of a pile foundation on sandy soil. The testing ground was simulated in the field and a standard pile-loading test was conducted. The test piles were divided into 3 types, Cases A, B and C, which is the location from the center of the slab by applying a vertical load. The interval between the piles was set to 8 cm. As a result of the pile foundation model test, the pavement settled when the vertical load was increased to 12kg from 1.5kg in sandy soil ground, particularly the maximum settlement of 0.04mm. Judging from the model chamber test, Case A showed compressive deformation, whereas Case B represented the compression and tensile forces with increasing vertical load. Case C showed an increase in tensile strain.