• Title/Summary/Keyword: L_3)$

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Estimation of Design Flood by the Determination of Best Fitting Order for LH-Moments (LH-모멘트의 차수에 따른 설계홍수량 추정)

  • Maeng, Sung-Jin;Lee, Soon-Hyuk
    • Proceedings of the Korean Society of Agricultural Engineers Conference
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    • 2002.10a
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    • pp.233-236
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    • 2002
  • This study was conducted to estimate the design flood by the determination of best fitting order for LH-moments of the annual maximum series at fifteen watersheds. Parameters of GEV distribution and flood flows of return period n years were derived by the methods of L, L1, L2, L3 and L4-moments. Frequency analysis of flood flow data generated by Monte Carlo simulation was performed by the methods of L, L1, L2, L3 and L4-moments using GEV distribution. Relative Root Mean Square Error (RRMSE), Relative Bias (RBIAS) and Relative Efficiency (RE) using methods of L, L1, L2, L3 and L4-moments for GEV distribution were computed and compared with those resulting from Monte Carlo simulation. At almost all of the watersheds, the more the order of LH-moments and the return periods increased, the more RE became, while the less RRMSE and RBIAS became. Consequently, design floods for the applied watersheds were derived by the methods of L3 and L4-moments among LH-moments in view of high confidence efficiency.

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Taxonomic Review of the Family Triglidae (Pisces, Scorpaeniformes) from Korea (한국산 성대과 (횟대목) 어류의 분류학적 재검토)

  • Lee, Chung-Lyul
    • Korean Journal of Ichthyology
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    • v.12 no.1
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    • pp.1-13
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    • 2000
  • The taxonomic review of the family Triglidae was made based on the specimens collected from the south-western coasts of Korea from 1986 to 1999. The family Triglidae from Korea was classified into 10 species belonging to 3 genera: Pterygotrigla hemisticta, Chelidonichthys kumu, Lepidotrigla, japonica. L. guentheri, L. alata, L. kishinouyei, L. kanagashira, L. microptera, L. hime and L. abyssalis. Of them, L. kanagashira was reported for the first time in South Sea of Korea. A key to species of the family Triglidae from Korea was provided, with description of their morphological characteristics and their distribution.

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Cloning of the Polyhedrin Gene-Containing DNA Fragment of Hyphantria cunea Nuclear Polyhedrosis Virus (흰불나방 핵다각체바이러스 다각체단백질 유전자포함 절편의 클로닝)

  • 박호영;진병래;박순식;김정일;깅석권
    • Korean journal of applied entomology
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    • v.32 no.1
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    • pp.51-60
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    • 1993
  • The polyhedrin gene-containing DNA fragment of Hyphantria cunea nuclear polyhedrosis virus (HcNPV) was localized by southern hybridization with Autographa california CPA EcoRI-I fragment (7.3 kb), Bombyx mori NPV PatI-F fragment (7 kb) and synthetic oligonucleotide(30-mer) as probes. the PstI-L(5.3 kb) fragment of HcNPV was cloned to E. coli and the plasmid of the fragment was named as pHcP-L(8.0 kb). The pHcP-L was physically mapped and subcloned to E. coli as pHcP-L1(4.7 kb), pHcP-L2(7.1 kb), pHcP-L3(5.3 kb), pHcP-L4(4.2 kb) and pHcP-L5(4.5 kb).

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Radiographic Parameters of Segmental Instability in Lumbar Spine Using Kinetic MRI

  • Jang, Se-Youn;Kong, Min-Ho;Hymanson, Henry J.;Jin, Tae-Kyung;Song, Kwan-Young;Wang, Jeffrey C.
    • Journal of Korean Neurosurgical Society
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    • v.45 no.1
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    • pp.24-31
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    • 2009
  • Objective : To investigate the effectiveness of radiographic parameters on segmental instability in the lumbar spine using Kinetic magnetic resonance imaging (MRI). Methods : Segmental motion, defined as excessive (more than 3 mm) translational motion from flexion to extension, was investigated in 309 subjects (927 segments) using Kinetic MRI. Radiographic parameters which can help indicate segmental instability include disc degeneration (DD), facet joint osteoarthritis (FJO), and ligament flavum hypertrophy (LFH). These three radiographic parameters were simultaneously evaluated, and the combinations corresponding to significant segmental instability at each level were determined. Results : The overall incidence of segmental instability was 10.5% at L3-L4, 16.5% at L4-L5, and 7.3% at L5-S1. DD and LFH at L3-L4 and FJO and LFH at L4-L5 were individually associated with segmental instability (p<0.05). At L4-L5, the following combinations had a higher incidence of segmental instability (p<0.05) when compared to other segments : (1) Grade IV DD with grade 3 FJO, (2) Grade 2 or 3 FJO with the presence of LFH, and (3) Grade IV DD with the presence of LFH. At L5-S1, the group with Grade III disc and Grade 3 FJO had a higher incidence of segmental instability than the group with Grade I or II DD and Grade 1 FJO. Conclusion : This study showed that the presences of either Grade IV DD or grade 3 FJO with LFH at L4-L5 were good indicators for segmental instability. Therefore, using these parameters simultaneously in patients with segmental instability would be useful for determining candidacy for surgical treatment.

Chitinase 3-like-1, a novel regulator of Th1/CTL responses, as a therapeutic target for increasing anti-tumor immunity

  • Kim, Do-Hyun;Choi, Je-Min
    • BMB Reports
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    • v.51 no.5
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    • pp.207-208
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    • 2018
  • Chitinase-Like Proteins (CLPs) are an evolutionarily conserved protein which lose their enzymatic activity for degrading chitin macromolecules. Chitinase-3-like-1 (Chi3l1) is a type of CLP that is highly expressed in epithelial cells, macrophages, etc., and is known to have correlations with type 2 inflammation and cancer. Although the increased level of Chi3l1 in the blood was reported in various disease patients, the function of Chi3l1 in adaptive immunity has been totally unknown. Recently, we found that Chi3l1 is expressed in T cells and has a negative regulatory role in T-cell activation and proliferation. A genetic ablation study of Chi3l1 in T cells showed hyperresponsiveness to TcR stimulation, which increased proliferation and Th1 differentiation. A significant increase of $IFN{\gamma}$ signaling in Chi3l1-deficient T cells synergistically increased Th1 and CTL functions against melanoma cells in vitro and in vivo. In addition, targeted knockdown by Chi3l1 siRNA complexed with the cell-penetrating peptide dNP2, which showed decreased pulmonary melanoma metastasis with increased infiltration of Th1 and CTL in the lung. This study first suggests that Chi3l1 is a novel regulator of Th1/CTL responses and could be a target for treating cancer to increase tumor immunity.

The Effects of Oryungsan-gagampang on Leptin Levels, Leptin Receptor Levels and Differentiation of 3T3-L1 Adipocyte (오차산감방이 3T3-L1 adipocyte의 leptin 및 leptin receptor 함량과 differentiation에 미치는 영향)

  • Kang Jung-Won;Choi Do-Young;Park Dong-Suk;Lee Jae-Dong
    • The Journal of Korean Medicine
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    • v.26 no.2 s.62
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    • pp.241-251
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    • 2005
  • Objectives: This experimental study was designed to investig:ue the effects of Oryungsan-gagampang on leptin and leptin receptor levels and differentiation of 3T3-L1 adipocyte. Methods: After 3T3-L1 adipocytes were incubated with various concentrations of Oryungsan-gagampang and Reductil(r) for 7 days, leptin and leptin receptor levels in 3T3-Ll adipocytes were measured by ELISA. To elucidate the mechanism of inhibitory effects of Oryungsan-gagampang on obesity, the 3T3-L1 adipocytes after oil red 0 staining were taken by digital photo system. Results: 1. Oryungsan-gagampang $1,000{\mu}g/ml$ significantly increased leptin levels in 3T3-L1 adipocytes in comparison with the control group (p<0.05), and Oryungsan-gagampang 0.1 10, $1,000{\mu}g/ml$ significantly increased leptin receptor levels in 3T3-L1 adipocytes in comparison with the control group (p<0.05). 2. Oryungsan-gagampang inhibited of differentiation of 3T3-L1 adipocytes. Conclusions: Oryungsan-gagampang showed significant effects on inhibiting differentiation of 3T3-Ll adipocytes, and increasing leptin levels and leptin receptor levels in 3T3-L1 adipocytes. Therefore, Oryungsan-gagampang could be used to treat obesity, but further studies are required.

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Prevalence of Leptospiral Antibodies in Pigs (돼지의 Leptospira 속균에 대한 혈중항체조사 -제천시 소재 도축장 출하돈 중심-)

  • 강신석;곽학구;김홍기
    • Korean Journal of Veterinary Service
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    • v.15 no.1
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    • pp.46-50
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    • 1992
  • This experiment was to investigate the Leptospiral antibody in the pigs with the serological test by the microscopic-agglutination-test (MAT) from November 1991. to Januaury 1992. Antigen(living antigen) was used L. icterohemorrhagiae, L. pomona, L. canicola, L. hardjo, L. ballum, L. australis, L. autumnalis, L. grippotyphosa, L. tarassovi, L. pyrogenes, L. bataviae, L. hebdomadis for the serolgical test in the pigs. The result obtained are summarized as follows of the total 202 serum samples examined, 1. Among the serum samples of 202 heads, 19 heads of the pigs(9.4%) were positive. 2. Among the positive samples of 19 heads, The detected were L. icterohemorhagiae 10 heads(5.0%), L. pomona 3 heads(1.5%), L. canicola 6 heads(3.0%). 3. Antibody titers of positive sera were ranging from 1:100 to 1 : 400. Serotiters appeared to be very low, 4. The seroprevalence of Leptospira in Chechon was higher than that other districts (5. 4% -5.8%), but the lower than Chung-nam, Kyonggi(13.7-15.9%)

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THE UNIT BALL OF THE SPACE OF BILINEAR FORMS ON ℝ3 WITH THE SUPREMUM NORM

  • Kim, Sung Guen
    • Communications of the Korean Mathematical Society
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    • v.34 no.2
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    • pp.487-494
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    • 2019
  • We classify all the extreme and exposed bilinear forms of the unit ball of ${\mathcal{L}}(^2l^3_{\infty})$ which leads to a complete formula of ${\parallel}f{\parallel}$ for every $f{\in}{\mathcal{L}}(^2l^3_{\infty})^*$. It follows from this formula that every extreme bilinear form of the unit ball of ${\mathcal{L}}(^2l^3_{\infty})$ is exposed.

Serum 25-Hydroxy Vitamin $D_3$ Analysis of Korean People (한국인 일반인의 혈청 25-Hydroxy Vitamin $D_3$의 분석)

  • Kim, Bo-Kyung;Jung, Hyun-Mi;Kim, Yun-Kyung;Kim, So-Young;Kim, Jee-Hyun
    • The Korean Journal of Nuclear Medicine Technology
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    • v.14 no.1
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    • pp.133-137
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    • 2010
  • Purpose: The main function of vitamin D is the mineralization of the brain by increase of calcium and phosphorus, in case it is insufficient in children, lime deposition on cartilage cannot occur so it leads to rachitis, and in adults, it leads to osteomalacia or osteoporosis. It is also strongly believed in the academic world that vitamin D can restrict the growth of cancer cells and prevent heart diseases, which is also somewhat proven in epidemiological researches. While the right density of vitamin D is still being studied, 20-32 ng/mL is believed to be the most ideal density. Therefore, I wanted analyze how much density of 25-Hydroxyvitamin D3 that Koreans possess. Materials and Methods: From February 20th, 2008 to April 21st, 2009, the collection of 2800 serums, from medical examination treated subjects by Neodin Medical Institute, have been tested. The targets were tested by 25-Hydroxyvitamin D (125I Kit: Diasorin, USA), and were analyzed by dividing into many different categories (gender, age, season, region). Results: The average density of male were 20 ng/mL, female 17.08 ng/mL. Per age groups, the density of males were as follows: 10~20-18 ng/mL, 21~30-17 ng/mL, 31~40-19 ng/mL, 41~50-21 ng/mL, 51~60-22 ng/mL, 61~70-22 ng/mL, 71~80-22 ng/mL and 81~90-19.9 ng/mL. Average density of females per age groups, were as follows: 10~20-16 ng/mL, 20~30-15.26 ng/mL, 30~40-16 ng/mL, 40~50-17 ng/mL, 50~60-19 ng/mL, 60~70-19 ng/mL, 70~80-19 ng/mL, and 80~90-17 ng/mL. Per seasons, From December to May, the subjects showed the density of 15.97 ng/mL, while from June to November, it showed 21.60 ng/mL. On density of males from January to April regionally, Seoul+Gyeonggi-Do-15.52 ng/mL, Gangwon-Do-15.33 ng/mL, Choongchung-Do-18.03 ng/mL, Jeonla-Do-18.68 ng/mL, Gyungsang-Do-18.76 ng/mL and Cheju Do-21.23 ng/mL. Conclusions: The vitamin D of Koreans is has been insufficient compared to the suggested amount. Ultraviolet rays, which is the main source of vitamin D is critical, therefore it is suggested that more outdoor activities can definitely help.

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Characteristics of Stormwater Runoff from Urban areas with Industrial Complex (산업단지의 도시 강우유출수 배출 특성)

  • Jung, Yong-Jun;Kim, Si-Won
    • Journal of Wetlands Research
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    • v.14 no.1
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    • pp.131-137
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    • 2012
  • This study was investigated to characterize the stormwater runoff pollutant materials from the urban area mixed with industrial area. Almost the similar rainfall pattern is shown during the 5 years, and the yearly precipitation was 5.2~6.6 mm. The first flushing effect during the early-stage rainfall-run off was observed in some events. EMC ranges are 19.3~39.9 mg/L for BOD, 45.2~190 mg/L for CODcr, 67.2~351 mg/L for TSS, 3.6~10.3 mg/L for TN, 1.2~2.5 mg/L for TP. Heavy metal are not detected except Zn which is observed at only one event. The particle size was distributed to 10 ${\mu}m$ at the 3% weight volume and the 50% cumulative weight percent was shown at 12 ${\mu}m$.