• Title/Summary/Keyword: LWR

Search Result 188, Processing Time 0.03 seconds

Oncologic Safety of Laparoscopic Wedge Resection with Gastrotomy for Gastric Gastrointestinal Stromal Tumor: Comparison with Conventional Laparoscopic Wedge Resection

  • Lee, Sejin;Kim, You Na;Son, Taeil;Kim, Hyoung-Il;Cheong, Jae-Ho;Hyung, Woo Jin;Noh, Sung Hoon
    • Journal of Gastric Cancer
    • /
    • v.15 no.4
    • /
    • pp.231-237
    • /
    • 2015
  • Purpose: Various laparoscopic wedge resection (LWR) techniques requiring gastrotomy for gastrointestinal stromal tumors (GISTs) of the stomach have been applied to facilitate tumor resection and preserve the remnant gastric volume. However, there is the possibility of cancer cell dissemination during these procedures. The aim of this study was to assess the oncologic safety of LWR with gastrotomy (LWR-G) compared to LWR without luminal exposure. Materials and Methods: Clinicopathologic and operative results of 193 patients who underwent LWR for gastric GIST were retrospectively analyzed from 2003 to 2013. We stratified the patients into two groups: LWR-G and LWR without gastrotomy (LWR-C). Clinicopathologic features, short-term outcomes, and long-term outcomes were compared. Results: A total of 26 patients underwent LWR-G, and 167 patients underwent LWR-C. The LWR-G group showed significantly more anterior wall-located (n=10, 38.5%), intraluminal (n=20, 76.9%), and ulcerative (n=13, 50.0%) tumors than the LWR-C group (n=33, 19.8%; n=96, 57.5%; n=46, 27.5%, respectively). Postoperative short-term outcomes did not differ between the two groups. When tumor staging was compared, no statistical difference was noted. There was no recurrence in the LWR-G group, while 2 patients in the LWR-C group experienced recurrence. The two recurrences in the LWR-C group were found in the liver and in the remnant stomach at 63 and 12 months after the operation, respectively. No gastric GIST-related death was recorded in any group during the study period. Conclusions: LWR-G for gastric GIST is an oncologically safe procedure even for masses with ulcerations.

Incremental Ensemble Learning for The Combination of Multiple Models of Locally Weighted Regression Using Genetic Algorithm (유전 알고리즘을 이용한 국소가중회귀의 다중모델 결합을 위한 점진적 앙상블 학습)

  • Kim, Sang Hun;Chung, Byung Hee;Lee, Gun Ho
    • KIPS Transactions on Software and Data Engineering
    • /
    • v.7 no.9
    • /
    • pp.351-360
    • /
    • 2018
  • The LWR (Locally Weighted Regression) model, which is traditionally a lazy learning model, is designed to obtain the solution of the prediction according to the input variable, the query point, and it is a kind of the regression equation in the short interval obtained as a result of the learning that gives a higher weight value closer to the query point. We study on an incremental ensemble learning approach for LWR, a form of lazy learning and memory-based learning. The proposed incremental ensemble learning method of LWR is to sequentially generate and integrate LWR models over time using a genetic algorithm to obtain a solution of a specific query point. The weaknesses of existing LWR models are that multiple LWR models can be generated based on the indicator function and data sample selection, and the quality of the predictions can also vary depending on this model. However, no research has been conducted to solve the problem of selection or combination of multiple LWR models. In this study, after generating the initial LWR model according to the indicator function and the sample data set, we iterate evolution learning process to obtain the proper indicator function and assess the LWR models applied to the other sample data sets to overcome the data set bias. We adopt Eager learning method to generate and store LWR model gradually when data is generated for all sections. In order to obtain a prediction solution at a specific point in time, an LWR model is generated based on newly generated data within a predetermined interval and then combined with existing LWR models in a section using a genetic algorithm. The proposed method shows better results than the method of selecting multiple LWR models using the simple average method. The results of this study are compared with the predicted results using multiple regression analysis by applying the real data such as the amount of traffic per hour in a specific area and hourly sales of a resting place of the highway, etc.

LIGHT WATER REACTOR (LWR) SAFETY

  • Sehgal Bal Raj
    • Nuclear Engineering and Technology
    • /
    • v.38 no.8
    • /
    • pp.697-732
    • /
    • 2006
  • In this paper, a historical review of the developments in the safety of LWR power plants is presented. The paper reviews the developments prior to the TMI-2 accident, i.e. the concept of the defense in depth, the design basis, the large LOCA technical controversies and the LWR safety research programs. The TMI-2 accident, which became a turning point in the history of the development of nuclear power is described briefly. The Chernobyl accident, which terrified the world and almost completely curtailed the development of nuclear power is also described briefly. The great international effort of research in the LWR design-base and severe accidents, which was, respectively, conducted prior to and following the TMI-2 and Chernobyl accidents is described next. We conclude that with the knowledge gained and the improvements in plant organisation/management and in the training of the staff at the presently-installed nuclear power stations, the LWR plants have achieved very high standards of safety and performance. The Generation 3+LWR power plants, next to be installed, may claim to have reached the goal of assuring the safety of the public to a very large extent. This review is based on the historical developments in LWR safety that occurred primarily in USA, however, they are valid for the rest of the Western World. This review can not do justice to the many fine contributions that have been made over the last fifty years to the cause of LWR safety. We apologize if we have not mentioned them. We also apologize for not providing references to many of the fine investigations, which have contributed towards LWR safety earning the conclusions that we describe just above.

Monte Carlo analysis of LWR spent fuel transmutation in a fusion-fission hybrid reactor system

  • Sahin, Sumer;Sahin, Haci Mehmet;Tunc, Guven
    • Nuclear Engineering and Technology
    • /
    • v.50 no.8
    • /
    • pp.1339-1348
    • /
    • 2018
  • The aim of this paper is to determine neutronic performances of the light water reactor (LWR) spent fuel mixed with fertile thorium fuel in a FFHR. Time dependent three dimensional calculations for major technical data, such as blanket energy multiplication, tritium breeding ratio, cumulative fissile fuel enrichment and burnup have been performed by using Monte Carlo Neutron-Particle Transport code MCNP5 1.4, coupled with a novel interface code MCNPAS, which is developed by our research group. A self-sustaining tritium breeding ratio (TBR>1.05) has been kept throughout the calculations. The study has shown that the fissile fuel quality will be improved in the course of the transmutation of the LWR spent in the FFHR. The latter has gained the reusable fuel enrichment level conventional LWRs between one and two years. Furthermore, LWR spent fuel - thorium mixture provides higher burn-up values than in light water reactors.

MICROSTRUCTURE AND MECHANICAL STRENGTH OF SURFACE ODS TREATED ZIRCALOY-4 SHEET USING LASER BEAM SCANNING

  • Kim, Hyun-Gil;Kim, Il-Hyun;Jung, Yang-Il;Park, Dong-Jun;Park, Jeong-Yong;Koo, Yang-Hyun
    • Nuclear Engineering and Technology
    • /
    • v.46 no.4
    • /
    • pp.521-528
    • /
    • 2014
  • The surface modification of engineering materials by laser beam scanning (LBS) allows the improvement of properties in terms of reduced wear, increased corrosion resistance, and better strength. In this study, the laser beam scan method was applied to produce an oxide dispersion strengthened (ODS) structure on a zirconium metal surface. A recrystallized Zircaloy-4 alloy sheet with a thickness of 2 mm, and $Y_2O_3$ particles of $10{\mu}m$ were selected for ODS treatment using LBS. Through the LBS method, the $Y_2O_3$ particles were dispersed in the Zircaloy-4 sheet surface at a thickness of 0.4 mm, which was about 20% when compared to the initial sheet thickness. The mean size of the dispersive particles was 20 nm, and the yield strength of the ODS treated plate at $500^{\circ}C$ was increased more than 65 % when compared to the initial state. This strength increase was caused by dispersive $Y_2O_3$ particles in the matrix and the martensite transformation of Zircaloy-4 matrix by the LBS.

Development of thermal conductivity model with use of a thermal resistance circuit for metallic UO2 microcell nuclear fuel pellets

  • Heung Soo Lee;Dong Seok Kim;Dong-Joo Kim;Jae Ho Yang;Ji-Hae Yoon;Ji Hwan Lee
    • Nuclear Engineering and Technology
    • /
    • v.55 no.10
    • /
    • pp.3860-3865
    • /
    • 2023
  • A metallic microcell UO2 pellet has a microstructure where a metal wall is connected to overcome the low thermal conductivity of the UO2 fuel pellet. It has been verified that metallic microcell fuel pellets provide an impressive reduction of the fuel centerline temperature through a Halden irradiation test. However, it is difficult to predict the effective thermal conductivity of these pellets and researchers have had to rely on measurement and use of the finite element method. In this study, we designed a unit microcell model using a thermal resistance circuit to calculate the effective thermal conductivity on the basis of the microstructure characteristics by using the aspect ratio and compared the results with those of reported metallic UO2 microcell pellets. In particular, using the thermal conductivity calculated by our model, the fuel centerline temperature of Cr microcell pellets on the 5th day of the Halden irradiation test was predicted within 6% error from the measured value.