• Proceedings of the KAIS Fall Conference
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• 2002.05a
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• pp.74-76
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• 2002

항균성 및 원적외선 방사량이 높은 원적외선 방사 항균 글라스 및 글라스 세라믹스의 양산화를 위한 유리 용융에 있어 대량용융의 가능성을 확인할 수 있었으며, 열처리온도는 5Li₂Oㆍ36CaOㆍ20TiO₂ㆍ27P₂O/sub 5/와 1Ag₂Oㆍ4Li₂Oㆍ36CaOㆍ20TiO₂ㆍ27P₂O/sub 5/ 조성에서 최적핵형성온도가 620℃, 최적결정성장온도가 각각 78℃, 800℃였다. 원가절감을 위산 건식법과 습식법의 결정상분석의 결과 피크의 차이는 거의 없었다. 이온교환의 경우 5.0mol AgNO₃수용액에 담지한 시편에서는 많은 LTP 결정상이 AgTP 결정상으로 변환되기 시작하여 1.0omol 농도의 AgNO₃ 수용액에서는 결정상의 주피크가 AgTP 절정상으로 변이 되었다. 이 결과로 AgNO₃ 수음액 0.5mol 농도 이상의 이온교환시 항균특성에 있어서도 매우 유리하리라 예상되어진다.

• Proceedings of the KIEE Conference
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• 2009.07a
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• pp.1623_1624
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• 2009

The use of arc tubes made of ceramic material further enhanced some of the metal halide lamp’s properties. These properties translate into higher efficacy with better color rendering, stable color through lamp long life. Recently, due to an increase in the application of the ceramic metal-halide lamp, the study for the property etc. according to Ballast's driving scheme and the study for arc tube material, optimization of gas and so on are being proceeded to improve the property of the lamp. Especially, to control ceramic metal-halide lamp, the vigorous study and practical use with respect to Electronic Ballast, which has been improved in the disadvantages of the conventional Magnetic Ballast are made. In this paper, Electrical characteristics and gas insulation destroy time are analyzed by comparing magnetic ballast with electronic ballast.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2010.06a
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• pp.166-166
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• 2010

향후 LED 기술의 지속적인 발전을 통하여 LED 조명제품의 효율이 향상될 것이 기대되므로 LED 조명 제품화에 대한 많은 연구가 수행되고 있다. LED를 조명용으로 사용하기 위해서는 구동회로, 광학설계, 방열설계 등을 포함한 조명시스템의 구성이 필요하다. 이 중 구동회로는 사용용도와 LED 구동특성 등에 따라 구동회로를 구성하여야 하며 이러한 구동회로 기술에는 벅, 부스트, 벅-부스트 컨버터 방식이 있다. 본 논문에서는 정전류 구동회로를 사용함에 있어 부스트 방식을 사용한 컨버터를 통해 7EA의 LED를 구동하고자 설계하였다. 이때 구동전류는 500 [mA]로 설정하였으며 이에 따라 입력전압에 대한 전기적 특성을 측정한 결과 7 [V]이상일 때부터 전류특성이 안정화 되는 특성을 확인할 수 있었다.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1995.10a
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• pp.125-132
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• 1995

In neurons, nitric oxide(NO) is produced by neuronal nitric oxide synthase following stimulation of N-methyl-D-aspartate(NMDA) receptors and the subsequent influx of Ca$\^$2+/. NO, induced in this manner, reportedly plays critical roles in neuronal plasticity, including neurite outgrowth, synaptic transmission, and long-term potentiation(LTP) (1-7). However, excessive activation of NMDA receptors has also been shown to be associated with various neurological disorders, including focal ischemia, epilepsy, trauma, neuropathic pain and chronic neurodegenerative maladies, such as Parkinson's disease, Hungtington's disease and amyotrophic lateral sclerosis(8). The paradox that nitric oxide(NO) has both neuroprotective and neurodestructive effects may be explained, at least in part, by the finding that NO effects on neurons are dependent on the redox state. This claim may be supported by the recent finding that tissue concentrations of cysteine approach 700 ${\mu}$M in settings of cerebral ischemia (9), levels of thiol that is expected to influence both the redox state of the system and the NO group itself(10).

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 1996.05a
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• pp.90-93
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• 1996

The conduction mechanisms of the off-current in low temperature ($\leq$600$^{\circ}C$) processed polycrystalline silicon thin film transistors (LTP poly-Si TFT's) has been systematically studied. Especially, the temperature and bias dependence of the off-current between unpassivated and passivated poly-Si TFT's was investigated and compared. The off-current of unpassivated poly-Si TFT's is due to a resistive current at low gate and drain voltage, thermal emission current at high gate, low drain voltage, and field enhanced thermal emission current in the depletion region near the drain at high gate and drain voltage. After hydrogenation, it was observed that the off-currents were remarkably reduced by plasma-hydrogenation. It was also observed that the off-currents of the passivated poly-Si TFT's are more critically dependent on temperature rather than electric field.

• Electrical & Electronic Materials
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• v.9 no.10
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• pp.1001-1007
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• 1996

The conduction mechanisms of the off-current in low temperature (.leq. >$600^{\circ}C$) processed polycrystalline silicon thin film transistors (LTP poly-Si TFT'S) have been systematically studied. Especially, the temperature and bias dependence of the off-current between hydrogenated and nonhydrogenated poly-Si TFT's were investigated and compared. The off-current of nonhydrogenated poly-Si TF's is because of a resistive current at low gate and drain voltage, thermally activated current at high gate and low drain voltage, and Poole-Frenkel emission current in the depletion region near the drain at high gate and drain voltage. After hydrogenation it has shown that the off -current mechanism is caused mainly by thermal activation and that the field-induced current component is suppressed.

• Proceedings of the Korea Information Processing Society Conference
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• 2002.04b
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• pp.1207-1210
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• 2002

장기간의 원자력발전소 운영과정에서 가동전 중검사는 설비의 건전성을 확인하는 매우 중요한 점검과정이다. 가동전 중검사 결과 많은 양의 검사데이터가 생산되며 이러한 검사데이터는 과거 검사결과와 비교하여 결함지시의 성장여부 등이 검토될 수 있어야 하며 후속 검사를 위한 기초 데이터로 활용될 수 있어야 한다. 또한 검사에 사용되는 검사장비, 검사자, 검사절차서, 관련 도면, Codes & Standards 등 검사자원의 체계적인 관리가 필요하며 이를 위한 정보시스템의 지원이 필수적이다. 또한 수작업으로 작성되는 가동전 중검사계획(LTP 등) 작성업무의 자동화가 필요하며, 검사계약이 경쟁체제로 전환됨에 따라 검사업체의 변경 여부에 관계없이 검사결과의 연속성이 유지되어야 하며 검사절차나 양식 등의 표준화가 필요하다. 본 논문에서는 이러한 현안사항을 개선할 수 있는 데이터베이스 응용시스템을 설계 및 구현하고 그 개발 과정을 소개한다.

• Journal of Life Science
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• v.22 no.11
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• pp.1487-1492
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• 2012

Peach (Prunus persica) has been recognized as a food allergen for over 20 years. However, there is little information about cross-reactivity with other foods. The aim of this study was to research cross-reactivity of Korean cherry and hot pepper on patients allergic to peach and its stability by digestive enzyme treatment. Peach, Korean cherry, and hot pepper proteins were extracted and separated by Tricine-SDS-PAGE analysis. The protein extracts had a wide range of molecular weight, from 3 kDa to more than 26 kDa, and displayed different patterns of protein bands on Tricine-SDS-PAGE. Peach allergic patients' sera were used to detect the allergenic protein in three samples. Three peach allergic patients' sera reacted strongly with 9 kDa protein of peach, which was the expected lipid transfer protein (LTP) as the major allergen of peach and was detected with anti-LTP1 polyclonal antibody. However, the reactivity of the 23 kDa protein in Korean cherry and hot pepper protein was stronger than that of the 9 kDa protein. The stability of protein extracts on digestive enzyme treatment was examined using simulated gastric fluids (SGF) and simulated intestinal fluids (SIF), in which digestive enzyme stability is one of the characteristics of allergen potentially causing food allergy. Findings confirmed that allergenic proteins in peach, Korean cherry, and hot pepper were not completely digested by SGF and SIF treatments from results of SDS-PAGE analysis. These results confirmed that Korean cherry and hot pepper might cause cross-reactivity in peach allergic patients, and its allergenic proteins have stability against digestive enzymes.

• Toxicological Research
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• v.17
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• pp.47-57
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• 2001

Alzheimer's disease (AD) is the most common cause of dementia in the elderly, and its pathology is characterized by the presence of numerous numbers of senile plaques and neurofibrillary tangles. Several genetic and transgenic studies have indicated that excess amount of $\beta$-amyloid protein (A$\beta$) is produced by mutations of $\beta$TEX>$\beta$-amyloid precursor protein and causes learning impairment. Moreover, $A\beta$ has a toxic effect on cultured nerve cells. To prepare AD model animals, we have examined continuous (2 weeks) infusion of $A\beta$ into the cerebral ventricle of rats. Continuous infusion of $A\beta$ induces learning impairment in water maze and passive avoidance tasks, and decreases choline acetyltransferase activity in the frontal cortex and hippocampus. Immunohistochemical analysis revealed diffuse depositions of $A\beta$ in the cerebral cortex and hippocampus around the ventricle. Furthermore, the nicotine-evoked release of acetylcholine and dopamine in the frontal cortex/hippocampus and striatum, respectively, is decreased in the $A\beta$-infused group. Perfusion of nicotine (50 $\mu\textrm{M}$) reduced the amplitude of electrically evoked population spikes in the CA1 pyramidal cells of the control group, but not in those of the $A\beta$-infused group, suggesting the impairment of nicotinic signaling in the $A\beta$-infused group. In fact, Kd, but not Bmax, values for ［$^3H$］ cytisine binding in the hippocampus significantly increased in the $A\beta$-infused rats. suggesting the decrease in affinity of nicotinic acetylcholine receptors. Long-term potentiation (LTP) induced by tetanic stimulations in CA1 pyramidal cells, which is thought to be an essential mechanism underlying learning and memory, was readily observed in the control group, whereas it was impaired in the $A\beta$-infused group. Taken together, these results suggest that $A\beta$ infusion impairs the signal transduction mechanisms via nicotinic acetylcholine receptors. This dysfunction may be responsible, at least in part, for the impairment of LTP induction and may lead to learning and memory impairment. We also found the reduction of glutathione- and Mn-superoxide dismutase-like immunoreactivity in the brains of $A\beta$-infused rats. Administration of antioxidants or nootropics alleviated learning and memory impairment induced by $A\beta$ infusion. We believe that investigation of currently available transgenic and non-transgenic animal models for AD will help to clarify the pathogenic mechanisms and allow assessment of new therapeutic strategies.

• Journal of Korean Society for Atmospheric Environment
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• v.32 no.4
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• pp.360-371
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• 2016

The goal of this research is to examine the recent decade-long (2000~2014) trends of national background concentrations over China, Japan, and Korea. Based on the Long-range Transboundary Air Pollutants in Northeast Asia (LTP) project, which is three-party collaboration project among three countries, we investigated the long-term trends of national background $PM_{10}$ concentrations in three countries over the recent 15 years, including the 2008 Beijing Olympic Game period. In accordance with the agreement among three countries, a total of 8 national background sites: three national background monitoring sites in China (2 sites in Dalian, and 1 in Xiamen), three sites in Korea (Ganghwa, Gosan, and Taean), and two sites in Japan (Oki and Rishiri), were chosen for the trend analysis. The results showed that Chinese background concentration recorded the highest level overall. However, the rapid declining recent trends of annual median ($50^{th}$-percentile) values were surprisingly detected since 2006 or 2007 in every site in China, with the most rapidly decreasing rate (- $18.6{\pm}10.3%$/year) over 2006~2007, and the second most rapidly decreasing rate (- $18.0{\pm}1.5%$/year) over 2007~2008. Based on the previous statistical literature, we concluded that this declining trends were due to the emission reduction of $PM_{10}$ concentrations in China for 2008 Beijing Olympic Game. In Korea, Ganghwa was also showing the decreasing trends over the recent years since 2006, which is also well accorded with the decreasing period of Chinese background concentrations. Taean also implied some impact of Beijing Olympic Game, showing small but detectable decreasing trends, while Gosan showed the increasing tendencies probably due to the near-urban influences. However, since 2012, most sites in both China and Korea showed strong increasing trends, undoubtedly implying the increasement of both emission in China and its long-range transport process toward Korea. Two sites in Japan, Oki and Rishiri recorded the lowest level of $PM_{10}$ level during whole period with the smallest deviations of measurements. Other discussions including the decade-long trends of $5^{th}$, $10^{th}$, $25^{th}$, $50^{th}$, $75^{th}$, $90^{th}$, $95^{th}$-percentiles of $PM_{10}$ background concentrations in three countries were also comparatively addressed here.