• Title/Summary/Keyword: LR

Search Result 930, Processing Time 0.029 seconds

Anti-apoptotic and neuroprotective effects of acupuncture techniques of tonification or sedation at HT9${\cdot}$LR1, HT3${\cdot}$KI10 on focal brain ischemic injury induced by intraluminal filament insertion in rats (심정격(心正格) 혈위(穴位)(소충(少衝)${\cdot}$대돈(大敦), 소해(少海)${\cdot}$음곡(陰谷))에 대한 영수(迎隨) 및 염전(捻轉) 보사(補瀉) 침자(鍼刺)가 국소 뇌허혈 유발 흰쥐의 항뇌세포고사와 신경보호 효과에 미치는 영향)

  • Byun, Jeong-Yun;Youn, Dae-Hwan;Na, Chang-Su
    • Korean Journal of Acupuncture
    • /
    • v.25 no.1
    • /
    • pp.229-246
    • /
    • 2008
  • Objectives : Acupoints of LR1(Dadun)${\cdot}$HT9(Shaochong), KI10(Yingu)${\cdot}$HT3(Shaohai) are used as controlling the diseases from heart problems. Especially, when they are used, tonification or sedation techniques method is taken as a controlling the medication for an early stroke in the Korean medicine. So the aim of this study is to investigate the anti-apoptotic and neuroprotective effects of Acupuncture techniques of tonification or sedation at LR1${\cdot}$HT9, KI10${\cdot}$HT3 on the focal ischemia induced by intraluminal filament insertion in rats. Materials and Methods : The focal ischemia was induced by intraluminal filament insertion into middle cerebral artery. The animals were divided into five groups (n=7 in each group) : Control group, no therapy group after ischemia induced; AT-1; acupuncture therapy group at LR1${\cdot}$HT9, KI10${\cdot}$HT3 after ischemia-induced. AT-2; acupuncture therapy at right LR1, HT9(forward direction), KI10${\cdot}$HT3(opposite direction) inserting to the direction of route of the each meridian. AT3; acupuncture therapy at right LR1, HT9(twirling forward with the thumb of right hand 9 times), KI10${\cdot}$HT3(twirling forward with the forefinger of right hand 6 times) AT-4; acupuncture therapy at right LR1, HT9(forward direction, twirling forward with the thumb of right hand 9 times), KI10${\cdot}$HT3(opposite direction, twirling forward with the forefinger of right hand 6 times) inserting to the direction of route of the each meridian. The anti-apoptotic and neuroprotective effects of Acupuncture techniques of tonification or sedation at LR1, HT9, KI10${\cdot}$HT3 were observed by Bax, Bcl-2, mGluR5, Cytochrome c, Cresyl violet and ChAT-stain. Results : The intensity of Bax and Bax/Bcl-2 ratio were increased in ACU-2 and ACU-4 group but decreased in ACU-3 group. The intensity of mGluR5 was increased in ACU-1, ACU-2, ACU-3 and ACU-4 group. The intensity of cytochrome c was decreased in ACU-3 and ACU-4 group. The density of neurons stained by Cresyl violet and ChAT were increased in ACU-1, ACU-3 and ACU-4 group. Conclusions : Our study suggests that acupuncture therapy of tonification at LR1, HT9 by twirling forward with the thumb of right hand 9times, sedation at KI10${\cdot}$HT3 by twirling forward with the forefinger of right hand 6 times after perpendicularly inserting needle shows anti-apoptotic and neuroprotective effects on cholinergic neuron in focal cerebral ischemia of the stroke in rats.

  • PDF

Comparison of Landslide Susceptibility Analysis Considering the Characteristics of Landslide Trigger Points (산사태 발생지점의 특성을 고려한 취약성 분석 비교)

  • Shin, Hyun Woo;Lee, Su Gon
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
    • /
    • v.36 no.2
    • /
    • pp.59-66
    • /
    • 2018
  • This study examined the correlation among topography, forest type, soil and geology in Inje area where landslides occurred during heavy rainfall from July 11 to July 18, 2006 to assess the landslide susceptibility. In order to assess the susceptibility of future landslides, landslides occurred in Inje area were classified into slide type and flow type, and slope angle, aspect, curvature, ridge and valley were extracted from the area. The landslide susceptibility was assessed by applying diameter class, age class, density, and forest type to Bayesianbased LR (Logistic Regression) model and WOE (Weight of Evidence) model, and the fitness of modeling was verified by predict rate curve. As the results of susceptibility assessment, using all landslides without no distintion, it was found that 75% of the LR model and 73% of the WOE model were fit in terms of the top 20% of the landslides. According to slide type and flow type in the top 20% of the landslides, it was found that 71% of the LR model and 69% of the WOE model were fit in terms of the slide type. Whereas, it was found that 86% of the LR model and 82% of the WOE model were fit in terms of the flow type. That is, the results of the LR model showed higher fitness than the results of the WOE model, and the fitness of the flow type was higher than that of the slide type. Consequently, it suggests that it is reasonable to assess and verify the landslide susceptibility according to the types of landslides.

Effects of Acupuncture on Lipid Composition in Rat Fed High Fat Diet (침자극(鍼刺戟)이 고지방식이(高脂肪食餌)를 급여(給與)한 흰쥐의 체지질구성(體脂質構成)에 미치는 영향(影響))

  • Oh Se-Woong;Lee Eun;Lee Joon-Moo
    • Korean Journal of Acupuncture
    • /
    • v.18 no.1
    • /
    • pp.65-80
    • /
    • 2001
  • Effects of $LR_3$(太衝), $GB_{39}$(懸鍾) and $SP_4$(公孫) acupuncture on lipid composition were investigated in rat fed high fat diet. The results obtained from this study are as follows : 1. In the all treatment groups, the body weight values after feeding the basal diet for 4 weeks were significantly decreased compared to the initial body weight. However the decrement of body weight showed a high in acupuncture groups compared to those of control group. In the acupuncture groups, the decrement of body weight showed a high in the $LR_3$ acupuncture groups. 2. The contents of plasma ${\beta}$-lipoprotein and free fatty acids showed a tendency to decrease in the acupuncture groups compared to those of control group and the values of $LR_3$ acupuncture groups showed a low in the acupuncture groups. 3. The contents of plasma triglyceride showed a low values in the complex treatment group of $LR_3,\;GB_{39}$ and $SP_4$. However among the other treatment groups, this values showed no significantly different. The contents of liver triglyceride showed a tendency to decrease in all acupuncture groups except to the complex treatment group of $GB_{39}$ and $SP_4$ acupuncture and in the acupuncture groups, $LR_3$ acupuncture groups were lower than $GB_{39}$ and $SP_4$ acupuncture groups. 4. The contents of plasma glucose showed a tendency to decrease by the acupuncture treatment and $LR_3$ acupuncture groups showed a lower values than other acupuncture groups. 5. In the values of plasma glutamic oxaloacetate transferase activity, $LR_3$ acupuncture group and the complex treatment group of $LR_3,\;GB_{39}$ and $SP_4$ acupuncture were a lower values than other treatment groups and among the other treatment groups showed no significantly different. The values of plasma glutamic pyruvate transferase activity showed no significantly different among all the treatment groups. 6. Contents of plasma and liver total cholesterol showed a tendency to decrease in $LR_3$ acupuncture groups. However those of the other groups showed no significantly different. 7. In the contents of plasma LDL-cholesterol, $LR_3$ acupuncture groups were a lower values than other groups, however among the other groups showed no significantly different. The contents of plasma HDL-cholesterol showed a tendency to increase in the acupuncture groups, however these values showed no significantly different.

  • PDF

Prognosis after Curative Resection of Single Hepatocellular Carcinoma with A Focus on LI-RADS Targetoid Appearance on Preoperative Gadoxetic Acid-Enhanced MRI

  • Ji Yoon Moon;Ji Hye Min;Young Kon Kim;Donglk Cha;Jeong Ah Hwang;Seong Eun Ko;Seo-Youn Choi;Eun Joo Yun;Seon Woo Kim;Ho-Jeong Won
    • Korean Journal of Radiology
    • /
    • v.22 no.11
    • /
    • pp.1786-1796
    • /
    • 2021
  • Objective: To evaluate the prognostic implications of preoperative magnetic resonance imaging (MRI) features of hepatocellular carcinoma (HCC) with a focus on those with targetoid appearance based on the Liver Imaging Reporting and Data System (LI-RADS), as well as known microvascular invasion (MVI) features. Materials and Methods: This retrospective study included 242 patients (190 male; mean age, 57.1 years) who underwent surgical resection of a single HCC (≤ 5 cm) as well as preoperative gadoxetic acid-enhanced MRI between January 2012 and March 2015. LI-RADS category was assigned, and the LR-M category was further classified into two groups according to rim arterial-phase hyperenhancement (APHE). The imaging features associated with MVI were also assessed. The overall survival (OS), recurrence-free survival (RFS), and their associated factors were evaluated. Results: Among the 242 HCCs, 190 (78.5%), 25 (10.3%), and 27 (11.2%) were classified as LR-4/5, LR-M with rim APHE, and LR-M without rim APHE, respectively. LR-M with rim APHE (vs. LR-4/5; hazard ratio [HR] for OS, 5.48 [p = 0.002]; HR for RFS, 2.09 [p = 0.042]) and tumor size (per cm increase; HR for OS, 6.04 [p = 0.009]; HR for RFS, 1.77 [p = 0.014]) but not MVI imaging features (p > 0.05) were independent factors associated with OS and RFS. Compared to the 5-year OS and RFS rates in the LR-4/5 group (93.9% and 66.8%, respectively), the LR-M with rim APHE group had significantly lower rates (68.0% and 45.8%, respectively, both p < 0.05), while the LR-M without rim APHE group did not significantly differ in the survival rates (91.3% and 80.2%, respectively, both p > 0.05). Conclusion: Further classification of LR-M according to the presence of rim APHE may help predict the postoperative prognosis of patients with a single HCC.

Effects of Treatment with Acupuncture, Moxibustion and Electro-Acupuncture at Large Intestine Meridian and Liver Meridian on the Serum Gastrin Level in Rats (합곡(合谷)·태충(太衝), 간유(肝兪)·대장유(大腸兪) 동시(同時) 취혈(取穴)이 정상(正常) 백서(白鼠) 위기능(胃機能)에 미치는 영향(影響))

  • Kim, Yong-jeong;Yu, Yun-cho;Kim, Kang-san
    • Journal of Acupuncture Research
    • /
    • v.21 no.3
    • /
    • pp.169-178
    • /
    • 2004
  • Objective : This study was designed to investigate the effects of acupuncture, moxibustion and electro-acupuncture at LI4 and LR3, BL18 and BL25 on serum gastin level in rats. Methods : LI4 and LR3 which belong to Large Intestine Meridian and liver Meridian are acupuncture points frequently used for healing gastrointestinal disease in oriental medicine. BL18 and BL25 which belong to Bladder Meridian are acupuncture points used for healing hepatic disease and intestinal disease in oriental medicine. Serum gastrin level by radioimmnunoassay was measured at 3 days after acupuncture, moxibustion and electro-acupuncture of those acupoints. Results & Conclusion : Moxibustion applied to the BL18 acupoint, BL25 acupoint decreased gastrin level of serum, but moxibustion applied to the BL18+BL25 acupoints did not produced significant effect. Acupuncture applied to the LI4 acupoint, LR4 acupoint did not produced significant effect, but acupuncture applied to the LI4+LR4 acupoints increased gastrin level of serum, Electro-acupuncture applied to the LI4 acupoint, LR4 acupoint increased gastrin level of serum, and electro-acupuncture applied to the LI4+LR4 acupoints also increased gastrin level of serum.

  • PDF

Performance analysis of UWB receiver using PPM and BPSK modulation scheme in the LR-WPAN System (LR-WPAN 시스템에서 PPM+BPSK 변조 방식을 사용하는 UWB 송수신기의 성능 분석)

  • Lee, Kyoung-Tak;Lim, Dong-Guk;Sohn, Sung-Hwan;Kim, Jae-Moung
    • The Journal of The Korea Institute of Intelligent Transport Systems
    • /
    • v.5 no.2 s.10
    • /
    • pp.19-28
    • /
    • 2006
  • In the IEEE 802.15.4a system, they require simple, economical and low power consumption transmitter and receiver to transmit low rate data and to identify distance and location. To meet these requirements, LR-WPAN system use transmitter and receiver with simple modulation and demodulation scheme. In this paper, use PPM+BPSK modulation and windowing scheme to overcome multipath fading effect. Then we apply this channel estimation scheme to LR-WPAN system and compare performance depends on transmitter scheme. Proposed method using preamble to find channel characteristic out and we compensate distorted data with that information. Therefore we can detect signal easily at the demodulation part. Simulation result shows that performance evaluation is greater at the NLOS channel than LOS channel no matter what the receiver scheme.

  • PDF

Design of Time Synchronizer for Advanced LR-WPAN Systems (개선된 LR-WPAN 시스템을 위한 시간 동기부 설계)

  • Park, Mincheol;Lee, Dongchan;Jang, Soohyun;Jung, Yunho
    • Journal of Advanced Navigation Technology
    • /
    • v.18 no.5
    • /
    • pp.476-482
    • /
    • 2014
  • Recently, with the growth of various sensor applications, the need of wireless communication systems which can support variable data rate is increasing. IEEE 802.15.4 LR-WPAN system using 2.45 GHz frequency band is very popular for the sensor applications. However, since LR-WPAN only supports the data rate of 250 kbps, it has a limit to be applied to various sensor networks. Therefore, we define the preamble structure which can support the data rates of 31.25 kbps, 62.5 kbps, 125 kbps, and present the low-complexity hardware architecture for time synchronizer based on double-correlation algorithm which can resist the CFO (carrier frequency offset). Implementation results show that the proposed time synchronizer include the logic slice of 18.36 K and four DSP48s, which are reduced at the rate of 79.1% and 99.4%, respectively, compared with existing architecture.

Adaptive Beacon Scheduling Algorithm to Reduce End-to-End Delay in Cluster-tree based LR-WPAN (클러스터-트리 기반 LR-WPAN에서 End-to-End 지연시간을 줄이기 위한 적응적 Beacon 스케줄링 알고리즘)

  • Kang, Jae-Eun;Park, Hak-Rae;Lee, Jong-Kyu
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.34 no.3B
    • /
    • pp.255-263
    • /
    • 2009
  • In this paper, we propose an adaptive beacon scheduling algorithm to control a reception period of actual data according to variation of amount of traffic in IEEE 802.15.4 LR-WPAN(Low Rate-Wireless Personal Area Network) with the cluster-tree topology. If a beacon interval is shortened, the amount of the traffic a node receives can be increased while consumption of the energy can be also increased. In this sense, we can achieve optimal on orgy consumption by controlling the beacon interval when the amount of data to be received is being decreased. The result of simulation using NS-2 shows that the proposed algorithm improves performances in terms of packet loss rate and end-to-end delay compared with algorithm using a fixed beacon interval. For a design of cluster-tree based LR-WPAN managing delay-sensitive services, the proposed algorithm and the associated results can be applied usefully.

Design and Verification of IEEE 802.15.4 LR-WPAN 2.4GHz Base-band for Ubiquitous Sensor Network (유비쿼터스 센서 네트워크를 위한 IEEE 802.15.4 LR-WPAN 2.4GHz 베이스 밴드 설계 및 검증)

  • Lee Seung-Yerl;Kim Dong-Sun;Kim Hyun-Sick;Chung Duck-Jin
    • Journal of the Institute of Electronics Engineers of Korea TC
    • /
    • v.43 no.1 s.343
    • /
    • pp.49-56
    • /
    • 2006
  • This paper describes the design and the verification of IEEE 802.15.4 LR-WPAN 2.4GHz Physical layer for Ubiquitous Sensor Network(USN). We designed the Carrier Frequency Offset(CFO) compensation satisfied the frequency tolerance of IEEE 802.15.4 LR-WPAN and the adaptive matched filter that re-setting of the threshold for the symbol synchronization of the various USN environment. The multiplications is reduced 1/16 by this method each other at i, q phases and has 0.5dB performance improvement in detection probability. Proposed baseband system is designed with verilog HDL and implemented using FPGA prototype board.

Outcome of Management of Local Recurrence after Immediate Transverse Rectus Abdominis Myocutaneous Flap Breast Reconstruction

  • Lee, Taik Jong;Hur, Wu Jin;Kim, Eun Key;Ahn, Sei Hyun
    • Archives of Plastic Surgery
    • /
    • v.39 no.4
    • /
    • pp.376-383
    • /
    • 2012
  • Background No consensus has been reached regarding the outcome of management of local recurrence after transverse rectus abdominis myocutaneous (TRAM) flap breast reconstruction. This study demonstrated the presentation, management, and outcomes of local recurrence after immediate TRAM breast reconstruction. Methods A comparison was conducted among 1,000 consecutive patients who underwent immediate breast reconstruction with a pedicled TRAM flap (TRAM group) and 3,183 consecutive patients who underwent only modified radical mastectomy without reconstruction (MRM group) from January 2001 to December 2009. The presentation, treatment, and outcome including aesthetics and overall survival rate were analyzed. Results Local recurrences occurred in 18 (1.8%) patients (TRAM-LR group) who underwent TRAM breast reconstruction and 38 (1.2%) patients (MRM-LR group) who underwent MRM only (P=0.1712). Wide excision was indicated in almost all the local recurrence cases. Skin graft was required in 4 patients in the MRM-LR group, whereas only one patient required a skin graft to preserve the mound shape in the TRAM-LR group. The breast mound was maintained in all 17 patients that survived in the TRAM-LR group even after wide excision. The overall survival rate was 94.4% in the TRAM-LR group and 65.8% in the MRM-LR group (P=0.276). Conclusions Local recurrence after immediate TRAM flap breast reconstruction could be detected without delay and managed effectively by multiple modalities without reducing overall survival rates. Breast mound reconstruction with soft autologous tissue allowed for primary closure in most of the cases. In all of the patients who survived, the contour of their reconstructed breast remained.