• Journal of Platform Technology
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• v.6 no.1
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• pp.24-30
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• 2018

LMT consisting of 10 landscape elements is one of psychology diagnosis method for inspecting the psychological state of client. In this paper, we make knowledge base accumulating knowledge about LMT landscape elements. By using this knowledge base, we also propose and implement LMT diagnosis assistance system generating LMT inspection report being a result of diagnosis. This proposed system generates diagnosis report based on LMT knowledge base which accumulate knowledge from plenty of reference and research project, that's why we improve the objectivity of diagnosis results. And new knowledge about LMT can be accumulated in knowledge base, so the system proposed in this paper can be extensible continuously. The implementation of system proposed in this paper offers web-based services. To show effectiveness of the system, we diagnose the actual case by using the system, and show the diagnosis result.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.4
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• pp.670-677
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• 2020

Objective: Interleukin-6 (IL-6) is a T cell-derived B cell stimulating factor which plays an important role in inflammatory diseases. In this study, the pharmacokinetic properties of LMT-28 including physicochemical property, in vitro liver microsomal stability and an in vivo pharmacokinetic study using BALB/c mice were characterized. Methods: LMT-28 has been synthesized and is being developed as a novel therapeutic IL-6 inhibitor. The physicochemical properties and in vitro pharmacokinetic profiles such as liver microsomal stability and Madin-Darby canine kidney (MDCK) cell permeability assay were examined. For in vivo pharmacokinetic studies, pharmacokinetic parameters using BALB/c mice were calculated. Results: The logarithm of the partition coefficient value (LogP; 3.65) and the apparent permeability coefficient values (P_app; 9.7×10^-6 cm/s) showed that LMT-28 possesses a moderate-high cell permeability property across MDCK cell monolayers. The plasma protein binding rate of LMT-28 was 92.4% and mostly bound to serum albumin. The metabolic half-life (t_1/2) values of LMT-28 were 15.3 min for rat and 21.9 min for human at the concentration 1 μM. The area under the plasma drug concentration-time curve and C_max after oral administration (5 mg/kg) of LMT-28 were 302±209 h·ng/mL and 137±100 ng/mL, respectively. Conclusion: These data suggest that LMT-28 may have good physicochemical and pharmacokinetic properties and may be a novel oral drug candidate as the first synthetic IL-6 inhibitor to ameliorate mammalian inflammation.

• Proceedings of the Korean Society of Laser Processing Conference
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• 2002.11a
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• pp.87-89
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• 2002

• International Journal of Advanced Culture Technology
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• v.9 no.2
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• pp.64-71
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• 2021

The purpose of this study is to analyze the impact of participatory design workshops conducted to design forest play spaces that reflect young children's needs and demands on the development of spatial concepts in young children. As a research method for this purpose, we used the participatory design workshop (6 times) and Landscape Montage Techniques (LMT). We conducted this study at the "Songsan-mulbit Forest Experience Center for children (FECC)" located in Gwangsan-gu, Gwangju Metropolitan City, from the second week of May to third week of June 2018 for preschoolers in K-kindergarten (six and seven-year-old integrated classes; 41 preschoolers in total). We conducted the LMT evaluation on the same preschoolers before and after the workshop, and the drawings of 39 preschoolers drawn for LMT evaluation before and after the workshop were subject to the final evaluation. As a result of the study, the cognitive levels for the spatial concept after the workshop are higher than those for the spatial concept before the workshop, especially showed the result of comparing the LMT values of 6 age and 7 age, there were significant differences on pre and post workshop in p<0.01.

• Asian-Australasian Journal of Animal Sciences
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• v.11 no.1
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• pp.1-7
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• 1998

A total of 120 pigs $(L\;{\times}\;LW\;{\times}\;D)$ averaged 14.16 kg of body weight were reared under six dietary treatments to evaluate the effects of amino acid supplementation on their performances. Treatments were 1) 18% CP diet (control); 2) 15% CP+0.28% Lys (B, 15L); 3) B+0.06% Met (15LM); 4) B+0.13% Thr (15LT) ; 5) B+0.06% Met+0.13% Thr (15LMT); 6) B+0.06% Met+0.13% Thr+0.05% Trp (15LMTT). Each treatment had 4 replicates with 5 pigs per replicate. The daily weight gains were statistically similar in 15LMT, 15LMTT and control groups. Threonine and methionine supplementation resulted in improved growth performance and nutrient digestibilities, while tryptophan supplementation had little beneficial effect. However, the best feed conversion was found in the control group. Dry. matter and CP digestibilities were improved in the 15LMT and 15LMTT groups. Gross energy, crude fat and phosphorus digestibilities were not affected by the treatment. Among the 15% CP groups, nitrogen digestibility showed the tendency to be increased as the more synthetic amino acids were added. Dry matter and nitrogen excretions were significantly reduced by feeding low protein, amino acid fortified diets, while phosphorus excretion was not influenced. Essential amino acids digestibility was higher in 15LT, 15LMT and 15LMTT groups and lower in the control. The 15LT group showed the best lysine digestibility, and methionine digestibilities were higher in all treated groups than control one. Threonine digestibilities higher in 15LT 15LMT, and 15LMTT than the control. The result shows that threonine and methionine should be added to the diet containing 15% CP diet, fortified with lysine to get same performance of 18% CP diet.

• Computers and Concrete
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• v.7 no.4
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• pp.285-301
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• 2010

In this work we first review the statistical data on large fires in urban areas, presenting a detailed list of causes of fires, the type of damage to concrete and reinforced concrete structures. We also present the modern experimental approach for studying the fire-resistance of different structural components, along with the role of numerical modeling to provide more detailed information on quantifying the temperature and heat flux fields. In the last part of this work we provide the refined models for assessment of fire-induced damage in structures built of concrete and/or reinforced-concrete. We show that the refined models of this kind are needed to provide a more thorough explanation of damage and to complete the damage assessment and post-fire evaluations.

• Computers and Concrete
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• v.5 no.4
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• pp.417-434
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• 2008

This paper deals with damage induced anisotropy modeling for concrete-like materials. A thermodynamics based constitutive relationship is presented coupling anisotropic damage and elasticity, the main idea of the model being that damage anisotropy is responsible for the dissymmetry tension/compression. A strain written damage criterion is considered (Mazars criterion extended to anisotropy in the initial model). The biaxial behavior of a family of anisotropic damage model is analyzed through the effects of yield surface modifications by the introduction of new equivalent strains.

• Advances in aircraft and spacecraft science
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• v.3 no.3
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• pp.317-330
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• 2016

Nowadays, the interest of aerospace and automotive industries on virtual testing of medium-frequency vibrational behavior of shallow shell structures is growing. The development of software capable of predicting the vibrational response in such frequency range is still an open question because classical methods (i.e., FEM, SEA) are not fully suitable for the medium-frequency bandwidth. In this context the Variational Theory of Complex Rays (VTCR) is taking place as an ad-hoc technique to address medium-frequency problems. It is a Trefftz method based on a weak variational formulation. It allows great flexibility because any shape function that satisfies the governing equations can be used. This work further develops such theory. In particular, orthotropic materials are introduced in the VTCR formulation for shallow shell structures. A significant numerical example is proposed to show the strategy.

• Journal of Gifted/Talented Education
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• v.24 no.2
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• pp.313-333
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• 2014

The purpose of this study was to examine self esteem and reactions on LMT projective technique to a group of scientifically gifted high school students and general high school students. For that purpose, 113 participants from scientifically gifted high school and general high school were asked to fill out self esteem questionnaire and draw a LMT. The results were analyzed by using SPSS.PASW18. The results are as follows: First, overall self esteem of gifted students were higher than general students. Second, reactions on LMT of gifted students and general students were examined. As a result, there were statistically significant differences in four items; integration of landscape composition, expression of distance and space, number of additional items, existence of doors and windows. The result of this study showed significant differences between the two groups in self esteem and LMT scores.

• Advances in aircraft and spacecraft science
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• v.3 no.2
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• pp.171-195
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• 2016

The present paper is a review of the main activities carried out within the context of the COMPTINN' program, a joint research project founded by a FUI program (Fonds $Unifi{\acute{e}}s$ $Interminist{\acute{e}}riels$) in which four research teams focused on the thermo-oxidation behaviour of HTS-TACTIX carbon-epoxy composite at 'high' temperatures ($120^{\circ}C-180^{\circ}C$). The scientific aim of the COMPTINN' program was to better identify, with a multi-scale approach, the link between the physico-chemical mechanisms involved in thermo-oxidation phenomena, and to provide theoretical and numerical tools for predicting the mechanical behaviour of aged composite materials including damage onset and development.