• 제목/요약/키워드: LMP

검색결과 132건 처리시간 0.026초

Isolation and Characterization of a Pollen-specific cDNA Clone from Easter Lily

  • Kim, Seong-Ryong;An, Gyu-Heung
    • Journal of Plant Biology
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    • 제39권3호
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    • pp.197-202
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    • 1996
  • A pollen-specific cDNA clone, LMP50, was isolated from the mature pollen cDNA library of the Easter lily. The LMP50 transcript was highly abundant in mture pollen grains but not detectable in other organs. The LMP50 cDNA clone contains 1383 nucleotides and two open reading frames. The first codes for a peptide of 15 amino acid residues. The role of this peptide is nuclear. The second encodes a protein containing 329 amino acid residues. This protein exhibited a significant homology to human tartrate-resistant acid phosphatase and porcine uteroferrin. Both of these enzymes have been suggested to play a role in iron transport. Therefore, LMP50 may act as an iron carrier protein in mature pollen grains.

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열간 금형펀치 제작을 위한 이종재 마찰용접과 고온 크리프 실시간 예측 및 AE에 의한 품질평가 (II)-크리프 수명예측 (Friction Welding of Dissimilar Hot Die Punch Materials and Its Creep Life Prediction and Quality Evaluation by AE ( II )-Creep Life Prediction by ISM)

  • 박일동;오세규;공유식;전태언
    • 한국해양공학회:학술대회논문집
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    • 한국해양공학회 2000년도 추계학술대회 논문집
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    • pp.26-32
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    • 2000
  • It was confirmed that the life predictive equation by LMP-ISM are effective only up to 10$^2$hours and can not be used for long times of 10$^3$~10$^{5}$ hours, but that by ISM can be used for long times creep life prediction with more reliability. The predictive creep life equation of ISM has better reliability than those by LMP and LMP-ISM, and its realizably is getting better for long time creep prediction(10$^3$~10$^{5}$ H).

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박판 크리프 수명평가에 마찰계수의 영향 (Effects of Friction Coefficient on Creep Life Assessment of Sheet)

  • 정지용;임지우;금영탁
    • 소성∙가공
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    • 제19권7호
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    • pp.435-440
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    • 2010
  • The creep life of 9Cr1MoVNb steel, in terms of Larson-Miller parameter(LMP), was evaluated by small punch(SP) creep simulation and verified by uniaxial creep test. By employing the elastoplastic FEM(finite element method), the small punch creep behaviors associated with various friction coefficients were simulated to identify a real friction phenomena. The friction coefficient, ${\mu}$=0.7, determined by comparing deflection history was used in the small punch creep simulation to find the equivalent stresses with which the relationship between punch load and uniaxial creep stress was found. The creep life was then predicted by the LMP, which was the relationship among the rupture time, temperature, and stress. Finally, the LMP calculated by SP-creep simulation was compared with that had computed by the uniaxial creep test and fairly matched LMPs were found.

Determination of Frequency of Epstein-Barr Virus in Non-Hodgkin Lymphomas Using EBV Latent Membrane Protein 1 (EBV-LMP1) Immunohistochemical Staining

  • Ishtiaq, Sheeba;Hassan, Usman;Mushtaq, Sajid;Akhtar, Noreen
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권6호
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    • pp.3963-3967
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    • 2013
  • Background: The presence of Epstein-Barr virus (EBV) in Non-Hodgkin's lymphoma can be identified by immunohistochemistry for detection of EBV latent membrane protein (LMP). The role of EBV as an etiologic agent in the development of non-Hodgkin lymphoma has been supported by detection of high levels of latent membrane protein 1 (LMP-1) expression in tumors. However, no study has been conducted in a Pakistani population up till now to determine the frequency of Epstein-Barr virus positivity. The objective of our study was to determine a value for non-Hodgkin lymphoma patients using EBV LMP-1 immunostaining in our institution. Materials and Methods: This study was carried out at the Department of Histopathology, Armed Forces Institute of Pathology (AFIP), Pakistan from December 2011 to December 2012. It was a cross sectional study. A total of 71 patients who were diagnosed with various subtypes of NHL after histological and EBV LMP-1 immunohistochemical evaluation were studied. Sampling technique was non-probability purposive. Statistical analysis was achieved using SPSS version 17.0. Mean and SD were calculated for quantitative variables like patient age. Frequencies and percentages were calculated for qualitative variables like subgroup of NHL, results outcome of IHC for EBV and gender distribution. Results: Mean age of the patients was $53.6{\pm}16$ years (Mean${\pm}$SD). A total of 50 (70.4%) were male and 21 (29.6%) were female. Some 9 (12.7%) out of 71 cases were positive for EBV-LMP-1 immunostaining, 2 (22.2%) follicular lymphoma cases, 1 (11.1%) case of T-cell lymphoblastic lymphoma, 4 (44.4%) cases of diffuse large B cell lymphomas, 1 (11.1%) mantle cell lymphoma and 1 (11.1%) angioimmunoblastic T cell lymphoma case. Conclusion: In our study, frequency of EBV in NHL is 12.7% and is mostly seen in diffuse large B cell lymphoma. This requires further evaluation to find out whether this positivity is due to co-infection or has a role in pathogenesis.

Deletion Analysis of the Major NF-${\kappa}B$ Activation Domain in Latent Membrane Protein 1 of Epstein-Barr Virus

  • Cho, Shin;Lee, Won-Keun
    • Journal of Microbiology
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    • 제37권4호
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    • pp.256-262
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    • 1999
  • Latent membrane protein 1 (LMP1) of the Epstein-Barr virus (EBV) is an integral membrane protein with six transmembrane domains, which is essential for EBV-induced B cell transformation. LMP1 functions as a constitutively active tumor necrosis factor receptor (TNFR) like membrane receptor, whose signaling requires recruitment of TNFR-associated factors (TRAFs) and leads to NF-${\kappa}B$ activation. NF-${\kappa}B$ activation by LMP1 is critical for B cell transformation and has been linked to many phenotypic changes associated with EBV-induced B cell transformation. Deletion analysis has identified two NF-${\kappa}B$ activation regions in the carboxy terminal cytoplasmic domains of LMP1, termed CTAR1 (residues 194-232) and CTAR2 (351-386). The membrane proximal C-terminal domain was precisely mapped to a PXQXT motif (residues 204-208) involved in TRAF binding as well as NF-${\kappa}B$ activation. In this study, we dissected the CTAR2 region, which is the major NF-${\kappa}B$ signaling effector of LMP1, to determine a minimal functional sequence. A series of LMP1 mutant constructs systematically deleted for the CTAR2 region were prepared, and NF-${\kappa}B$ activation activity of these mutants were assessed by transiently expressing them in 293 cells and Jurkat T cells. The NF-${\kappa}B$ activation domain of CTAR2 appears to reside in a stretch of 6 amino acids (residues 379-384) at the end of the carboxy terminus.

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표면복제를 사용한 mod HP강 개질로 튜브의 잔여수명 평가에 대한 연구 (Residual Life Assessment of mod HP Reformer Tubes Using Surface Replication Methods)

  • 류형기;;방효중;윤기봉
    • 한국가스학회지
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    • 제25권5호
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    • pp.30-36
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    • 2021
  • 정유 및 석유화학산업의 개질로 튜브에 사용되는 mod HP강에 대한 잔여수명의 예측법을 튜브의 표면 금속조직에 석출된 탄화물의 면적분율에 대한 정량적인 평가를 통해 연구하였다. 표면복제법을 활용한 미세조직 분석을 통하여 탄화물의 면적분율과 잔여수명 사이의 관계를 실험적으로 구하였다. 신재(Virgin)와 950 ℃의 개질로에서 1.8, 6.0, 7.2, 8.5, 9.7 및 16.2년 실제 사용한 튜브들을 광학현미경(OM)을 사용하여 관찰하였으며, 석출물의 면적분율을 Image J 프로그램을 이용한 정량적 이미지 분석에 의해 측정하였다. 석출물의 면적분율이 증가함에 따라 잔여수명이 감소하여 서로 반비례하는 결과를 보여주었다. 이 관계를 사용온도와 수명을 결합한 파라미터인 LMP로 나타내면, 신재에서 LMP 값이 가장 높게 나타났고, 사용시간이 증가할수록 LMP가 감소하여 잔여수명이 줄어 듦을 나타내었다. LMP와 탄화물의 면적분율과의 상관관계를 나타내는 관계식을 도출하였다. 도출한 관계식은 현장에서 잔여수명 평가를 위해 표면복제법 적용으로 면적분율을 측정하여 잔여수명을 평가하는데 사용될 수 있다.

Performance Comparison of Optimal Power Flow Algorithms for LMP Calculations of the Full Scale Korean Power System

  • Lee, Sungwoo;Kim, Wook;Kim, Balho H.
    • Journal of Electrical Engineering and Technology
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    • 제10권1호
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    • pp.109-117
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    • 2015
  • This paper proposes the comparison results of various optimal power flow algorithms (OPF) to calculate the locational marginal prices (LMP) of the unreduced full scale Korean transmission system. Five different types of optimal power flow models are employed: Full AC OPF, Cubic AC OPF, Quadratic AC OPF, Linear AC OPF and DC OPF. As the results, full AC OPF and cubic AC OPF model provides LMP calculation results very similar to each other while the calculation time of cubic AC OPF model is faster than that of the Full AC OPF. Other simplified OPF models, quadratic AC OPF, linear AC OPF and DC OPF offer erroneous results even though the calculation times are much faster than the Full AC OPF and the Cubic AC OPF. Given the condition that the OPF models sometimes fail to find the optimal solution due to the severe complexity of the Korean transmission power system, the Full AC OPF should be used as the primary OPF model while the Cubic AC OPF can be a promising backup OPF model for the LMP calculations and/or real-time operation.

Interference of Fisetin with Targets of the Nuclear Factor-κB Signal Transduction Pathway Activated by Epstein-Barr Virus Encoded Latent Membrane Protein 1

  • Li, Rong;Liang, Hong-Ying;Li, Ming-Yong;Lin, Chun-Yan;Shi, Meng-Jie;Zhang, Xiu-Juan
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권22호
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    • pp.9835-9839
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    • 2014
  • Fisetin is an effective compound extracted from lacquer which has been used in the treatment of various diseases. Preliminary data indicate that it also exerts specific anti-cancer effects. However, the manner in which fisetin regulates cancer growth remains unknown. In this study, we elucidated interference of fisetin with targets of the nuclear factor ${\kappa}B$ signal transduction pathway activated by Epstein-Barr virus encoding latent membrane protein 1 (LMP1)in nasopharyngeal carcinoma (NPC) cells, Results showed that fisetin inhibited the survival rate of CNE-LMP1 cells and NF-${\kappa}B$ activation caused by LMP1. Fisetin also suppressed nuclear translocation of NF-${\kappa}B$ (p65) and $I{\kappa}B{\alpha}$ phosphorylation, while inhibiting CyclinD1, all key targets of the NF-${\kappa}B$ signal transduction pathway. It was suggested that interference effects of fisetin with signal transduction activated by LMP1 encoded by the Epstein-Barr virus may play an important role in its anticancer potential.

송전망 축약을 위한 교육용 프로그램 개발 (An Educational Program for Reduction of Transmission Network)

  • 송형용;정윤원;원종집;박종배;신중린
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2008년도 제39회 하계학술대회
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    • pp.153-154
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    • 2008
  • This paper presents a window-based software package for the education and training for the reduction of power system by using locational marginal price (LMP), clustering, and similarity indices of each bus. The developed package consists of three modules: 1) the LMP module, 2) the Clustering module and 3) the Reduction module. Each module has a separated and interactive interface window. First of all, LMPs are created in the LMP module, and then the Clustering module carries out clustering based on the results of the LMP module. Finally, groups created in this Clustering module are reduced by using the similarity indices of each bus. The developed package displays a variety of tables for results of the LMPs of base network, voltages, phases and power flow of reduced network so that the user can easily understand the reduction of network. To demonstrate the performance of the developed package, it is tested for the IEEE 39-bus power system.

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LMP 복합사의 저온 염색성 (Dyeability of Low-melting Polyester at Low Temperature)

  • 황지현;김창남;마진숙;윤남식
    • 한국염색가공학회:학술대회논문집
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    • 한국염색가공학회 2012년도 제46차 학술발표회
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    • pp.49-49
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    • 2012
  • 바닥재 자카드직물에 사용이 예상되는 LMP(low meltig polyester) 복합사는 사염 시 높은 수축율 및 열융착의 가능성 때문에 일반적인 폴리에스테르의 염색조건에서는 염색이 불가하다. 따라서 적정의 수축율 내에서 가능한 염색조건에 대해 고찰하였다. LMP 복합사는 웅진케미컬에서 생산된 Regular PET/LMP(75:25) 260d/48f 원사를 사용하였다. 수축율은 KS K 0215에 준하여 측정하였다. 염색은 E-type 및 S-type(Foron Dark Blue S-WF) 분산염료를 사용하였으며, E-type 중에서는 아조계(Lumacron Blue SERL 200%) 와 안트라퀴논계(Foron Blue E-BL 150)의 2 종류를 사용하였다. 염색된 시료는 현미경 단면사진을 이용하여 염료의 내부확산을 확인하였으며, 환원세정 전후의 K/S 값을 측정하였다. LMP원사의 수축율을 시험한 결과 $90^{\circ}C$에서 9% 정도의 수축율을 나타내어, $90^{\circ}C$ 이상에서는 사염이 어려운 것으로 나타났다. 따라서 염색온도는 $80^{\circ}C$$90^{\circ}C$로 하였다. S-type의 염료를 이용한 경우 $90^{\circ}C$에서 4일 이상 염색해도 염착이 이루어지지 않아 대상 염료에서 제외하였다. E-type 염료인 경우 아조계는 흡진율은 높았으나 내부 regular PET에의 확산이 매우 느리고, 안트라퀴논계는 상대적으로 확산이 빠른 것으로 나타났다. 안트라퀴논계 분산염료는 $80^{\circ}C$에서 내부로의 확산에 4일 이상이 소요되며, $90^{\circ}C$에서는 2일 이상이 소요되었다. 이 후 환원세정에 의한 K/S 값의 변화 및 마찰견뢰도를 시험하였으며, 환원세정 후의 섬유단면 사진을 통해 염료의 migration성을 평가하였다.

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