• BMB Reports
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• v.39 no.4
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• pp.457-463
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• 2006

Insulin resistance is commonly observed in patients prior to the development of type 2 diabetes and may predict the onset of the disease. We tested the hypothesis that impairment in insulin stimulated glucose-disposal in insulin resistant patients would be reflected in the gene expression profile of skeletal muscle. We performed gene expression profiling on skeletal muscle of insulin resistant and insulin sensitive subjects using microarrays. Microarray analysis of 19,000 genes in skeletal muscle did not display a significant difference between insulin resistant and insulin sensitive muscle. This was confirmed with real-time PCR. Our results suggest that insulin resistance is not reflected by changes in the gene expression profile in skeletal muscle.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.28 no.5
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• pp.545-552
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• 2004

The purpose of this study is to improve the prediction ability of the atomization and vaporization processes of GDI spray. Several models have been introduced and compared. The atomization process was modeled using hybrid breakup model that is composed of Linearized Instability Sheet Atomization (LISA) model and Aerodynamically Progressed TAB (APTAB) model. The vaporization process was modeled using Spalding model and Abramzon ＆ Sirignano model. Exciplex fluorescence method was used for comparing calculated with experimental results. The experiment and computation were performed at the ambient pressure of 0.1 MPa, 0.5 MPa and 1.0 MPa and the ambient temperature of 293k and 473k. Comparison of calculated and experimental spray characteristics was carried out and the calculated results of GDI spray showed good agreement with experimental results.

• Journal of ILASS-Korea
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• v.7 no.3
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• pp.1-6
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• 2002

In this study numerical and experimental study on the spray atomization characteristics of a GDI injector is performed. To carry out numerical analysis, four hybrid models that are composed of conical sheet disintegration model, LISA model, DDB model, and RT model are used. The experimental results to evaluate the prediction accuracy of hybrid models are obtained by using phase Doppler particle analyzer and spray visualization system. It is shown that the prediction accuracy of hybrid model concerning spray developing process and spray tip penetration is good for all hybrid models, but the hybrid breakup models show different prediction of accuracy in the case of local radial SMD distribution.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.32 no.5D
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• pp.507-517
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• 2012

The main purpose of this study is to address flooding resilient land use management strategy based on the distributional characteristics of storm damage areas in Gyeonggi-do. The employed methods are 1) Exploratory Spatial Data Analysis (ESDA) to understand the spatial patterns of storm damage areas occurred from 2005 to 2009, 2) Local Indicator of Spatial Association (LISA) to examine spatial autocorrelation existed in storm damage areas for the year of 2009. The results show that 1) crop land damage is very sensitive to heavy precipitation, 2) damaged buildings are found in all over the Gyeonggi areas, but relatively more damages are in the regions closed to the City of Seoul, 3) damaged roads-bridges, streams, and reaches are found in mostly rural areas, 4) building and crop land damage occurs mostly in lowlands with different spatial patterns. These findings imply that 1) it will be useful to consider the average distances and slopes of damaged building and crop lands from streams for the decision making of land use management strategy, 2) further management efforts are required in the north, east, and south regions of Gyeonggi areas to prevent roads-bridge, stream, and reach damages, 3) the present land use pattern needs to be carefully investigated by considering the damage clustered areas for the year of 2009 based on watershed and municipality boundaries.

• Journal of the Korean Association of Geographic Information Studies
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• v.26 no.4
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• pp.173-187
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• 2023

In an era of population decline, depopulated regions facing challenges in attracting inbound population migration must enhance urban vitality through the attraction of living populations. This study focuses on Busan, a city experiencing population decline, comparing the spatiotemporal distribution characteristics of registered residents and living populations in various administrative districts (Eup-Myeon-Dong) using mobile communication big data. Administrative districts are typified based on population change patterns, and regional characteristics are analyzed using indicators related to urban decline and vitality. Spatiotemporal distribution analysis reveals generally similar density patterns between registered residents and living populations; however, a distinctive feature is observed in the city center areas where the density of registered residents is low, while the density of living populations is high. Divergent trends in spatial patterns of change between registered residents and living populations show clusters of registered population decline in low-density areas and clusters of living population decline in high-density areas. Areas adjacent to declining living populations exhibit large clusters of population changes, indicating a spillover effect from high-density to neighboring areas. Typification results reveal that, even in areas with a decline in registered residents, there is active population influx due to commuting or visiting. These areas sustain an increase in the number of businesses, confirming the presence of industrial and economic growth. However, approximately 47% of administrative districts in Busan are experiencing a decline in both registered residents and living populations, indicating ongoing regional decline. Urgent measures are needed for enhancing urban vitality. The study emphasizes the necessity of utilizing living population data as an urban planning indicator, considering the increasing limit distance of urban activities and growing interregional interaction due to advancements in transportation and communication.

• Journal of the Korean Association of Geographic Information Studies
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• v.22 no.4
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• pp.131-145
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• 2019

Korea has set up a radiation emergency planning zone based on the 「Act on Physical Protection and Radiological Emergency」 to protect residents living near nuclear power plants in the event of nuclear disasters. Little research has been conducted on the appropriateness of existing nuclear evacuation facilities because of a general lack of interest in nuclear accidents. This research addresses this gap by analyzing the location adequacy of evacuation facilities in Busan's emergency protection planning area based on vulnerable populations and accessibility analyses. The Gijang-gun which has the greatest risk, shows that only 4.05% of the total urban area was included in the evacuation service area within 5 minutes while only 36.93% of Geumjeong-gu and 37.23% of Haeundae-gu were included in the evacuation-enabled area. In addition, evaluation facilities in the elderly population hotspots were lacking, and there was a wide gap between dongs within the same Gu. Thus, additional evacuation facilities need to be designated and installed considering the spatial equity between areas and safety of both the public and vulnerable populations.

• Journal of Korea Technical Association of The Pulp and Paper Industry
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• v.31 no.5
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• pp.57-72
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• 1999

Traditional theories of the tensile failure of paper have assumed that uniform strain progresses throughout the sheet until an imperfection within the structure causes a catastrophic break. The resistance to tensile elongation is assumed to be elastic , at first, throughout the structure, followed by an overall plastic yield. However, linear image strain analysis (LISA) has demonstrated that the yield in tensile loading of paper is quite non-uniform throughout the structure, Traditional theories have failed to define the flaws that trigger catastrophic failure. It was assumed that a shive or perhaps a low basis weight area filled that role. Studies of the fracture mechanics of paper have typically utilized a well-defined flaw around which yield and failure could be examined . The flaw was a simple razor cut normal to the direction of tensile loading. Such testing is labeled mode I analysis. The included fla in the paper was always normal to the tensile loading direction, never at another orientation . However, shives or low basis weight zones are likely to be at random angular orientations in the sheet. The effects of angular flaws within the tensile test were examined. The strain energy density theory and experimental work demonstrate the change in crack propagation from mode I to mode IIas the initial flaw angle of crack propagation as a function of the initial flaw angle is predicted and experimentally demonstrated.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.40 no.1
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• pp.59-67
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• 2020

In this study, a suitable algorithm for each BRT stop type is presented through the network construction and algorithm design effect analysis through the LISA, a traffic signal program, for the BRT stop type in the BRT Design Guidelines, Ministry of Land, Transport and Maritime Affairs, 2010.6. It was. The phase insert technique is the most effective method for the stop before passing the intersection, the early green technique for the stop after the intersection, and the extend green technique for the mid-block type stop. The extension green technique is used only because it consists of BRT vehicles, general vehicles and pedestrians. Analyzed. After passing through the intersection, the stop was analyzed as 56.4 seconds for the total crossing time and 29.8 seconds for the delay time. In the mid-block type stop, the total travel time of the intersection was 40.5 seconds, the delay time was 9.6 seconds, the average travel time of up and down BRT was 70.2 seconds, the delay time was 14.0 seconds, and the number of passages was 29.

• Journal of the Economic Geographical Society of Korea
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• v.19 no.4
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• pp.694-711
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• 2016

This study analyzes the spatial characteristics of knowledge industry which has shown relatively rapid growth in the low-growth economy situation in recent years. In particular, we catch hold of the locational characteristics of the knowledge service industry which occupies the highest ratio by professional-expert jobs favoured by young generations, as well as estimate their occupational employment opportunities. By applying Location Quotient(LQ) and LISA, we reveal the spatial distribution patterns of publishing business, information service business and education service business in the Seoul Metropolitan area, and examine the changes in the spatial patterns during the last ten years. In order to understand the socio-economic factors which explain their locations, we apply the stepwise multiple regression analysis. Furthermore, we predict the changes distribution of Knowledge service industrial employment by applying Markov Chain Model. As the result, we found their clusters at the specific locations, while there is the significant variations in the socio-economic variables related their locations respectively. The related job opportunities of the knowledge service businesses in the Seoul Metropolitan area are predicted steady growth trend for the next four years, even though dull or stagnant trend is expected for other industries. This study provides basic resources to the planning for young generation employment problem.

• Transactions of the Korean Society of Automotive Engineers
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• v.14 no.4
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• pp.132-138
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• 2006

Numerical analysis about atomization and wall impingement process of hollow-cone fuel spray is performed by a modified KIVA code with hybrid model. The atomization process is modeled by using hybrid breakup model that is composed of Linearized Instability Sheet Atomization(LISA) model and Aerodynamically Progressed Taylor Analogy Breakup(APTAB) model. The Gosman model, which is based on the droplet behaviors after impingement determined by experimental correlations, is used for spray-wall impingement process. The LIEF technique was used to compare the results with those of experiment. The calculations and experiments are carried out at the ambient pressures of 0.1 MPa and 0.5 MPa and the ambient temperature of 293K. It was found that the calculated results show satisfactory agreement with experimental ones.