• Journal of Korean Medicine Rehabilitation
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• v.15 no.2
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• pp.17-30
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• 2005

Objectives : This study was designed to evaluate the changes of autonomic nervous system by heart rate variability(HRV) test on the musculoskeletal pain patients treated with acupuncture on the Back-su points and the unfixed points, and untreated healthy adults. Methods : This clinical study have been carried out with 64 cases of musculoskeletal pain patients and 26 healthy adults. 35 patients were treated with acupunctureon on the Back-su points(Group I) and 26 patients were treated on the Unfixed points(GroupII), and two groups were tested by HRV at pre and post acupuncture treatment. 26 healthy adults(GroupIII) were tested twice by HRV without any stimulation. Results : In Group I, VAS was decresased $5.83{\pm}1.62$ to $5.17{\pm}1.89$ significantly(p<0.05) after acupuncture treatment, and LF/HF ratio was decreased significantly(p<0.05) as compared with healthy control Group. In GroupII, SDNN & RMSSD were increased singnificantly(p<0.05) as compared with other Groups. in Group I & II, MHRT was decreased significantly(p<0.05) as compared with healthy control Group. Conclusions : These results suggest that acupuncture treatment on the Back-su points was able to reduce the pain, suppress the sympathetic activities and enhance the parasympathetic activities in musculoskeletal patients.

• Journal of Acupuncture Research
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• v.25 no.4
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• pp.71-80
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• 2008

Objectives : The 7-zonediagnostic system is a diagnostic device to predetermine bodily locations by measuring the energy of body. This study was to investigate the relation between the different patterns of Zone 4 of Factor AA in VEGA DFM 722 (VEGA, Germany), 7-zone-diagnositic system and heart rate variability. Methods : We made three groups according to the Factor AA patterns of VEGA DFM 722. The Factor AA pattern of Group A is that the red bar graph of zone 4 was higher than the normal range. The Factor AA patterns of Group B was that the red bar graph of zone 4 was located at the normal range. The Factor AA patterns of Group C was that the red bar graph of zone 4 was lower than the normal range. We investigated how to difference of the index of heart rate variability(HRV, LX-3202, LAXTHA, Korea) according to each groups. Results : Complexity, HRV-index, RMSSD, SDSD values of Group B were higher than other Groups. pNN50 values of Group B were lower than other groups. And Ln(TP), Ln(VLF), Ln(LF), Ln(HF) values of Group B were higher than other groups. Conclusions : We presumed that Group B was healthier than other groups for the stress.

• Journal of Sasang Constitutional Medicine
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• v.27 no.2
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• pp.231-239
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• 2015

Objectives The purpose of this study is to find out whether or not there are differences of effects when we count breaths on inspiration or expiration, and how differently the effects show up according to gender or Sasang Constitution Methods A group of 79 participants were enrolled and diagnosed Sasang Constitution by Sasang Constitution Diagnosis System of the Korea Institute of Oriental Medicine. Physical responses to respiratory changes were measured by Biofeedback sensors that were attached to the participants while they were seated comfortably on a sofa and breathing normally without counting for 5 minutes, counting on inspiration for 5 minutes, and counting on expiration for 5 minutes. Results and Conclusions 1. Mean heart rate and respiration rate decreased in association with breathing counting on inspiration and expiration more than breathing normally without counting. Especially respiration rate was stabilized during counting on inspiration and mean heart rate was stabilized during counting on expiration. 2. Interaction between breathing methods and gender did not appear. In comparison between gender, LF/HF ratio was higher in male during breathing normally without counting and counting on inspiration. Body temperature was higher in male during counting on inspiration and expiration. 3. Interaction between breathing methods and Sasang Constitution did not appear. In comparison between Sasang Constitution, mean heart rate was higher in Soyang-in, Soeum-in than Taeeum-in and abdominal amplitude was lower in Taeeum-in than Soeum-in.

• Journal of Biomedical Engineering Research
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• v.25 no.6
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• pp.623-628
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• 2004

This paper describes autonomic nervous system activities caused by hyperthermia of far-infrared ray on human body. Designed protocol and analysis algorithm were evaluated by experiments on 20 subjects to analyze the characteristic of heart rate variability(HRV) signals which could be analyzed by FFT power spectrum and time-frequency analysis. Using Poincare' plot analysis, LF and HF were compared with SD1 and SD2. During the experiment, subject was exposed to hyperthermic effects of far-infrared radiation. We could confirm that far-infrared ray, which was known to improve the blood circulation, stress state and enhancing thermal effect into human body, had an effect on human nervous system. As the hyperthermic temperature of far-infrared ray increased, the activity of cardiovascular system to sustain the homeostasis was observed by means of investigating the increase of the sympathetic activity.

• Journal of Biomedical Engineering Research
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• v.18 no.3
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• pp.285-290
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• 1997

In this paper, the power spectral analysis and the fractal analysis of heart rate variability(HRV) were performed to evaluate the effects of brain lesion on cardiovascular system and autonomic function for 24 normal subjects and 22 hemiplegic patients. The ECG and respiration signals were recorded at tilt angles of $0^{\circ}$ and $70^{\circ}$ for 5 and 6 minutes successively under the condition of frequency controlled respiration (0.25Hz). For normal subjects, HR, LF component, HF component and fractral dimension of HRV were distinctly changed after orthostatic stress, whereas, for hemiplegic patients, those were little changed. Complexity and variability of heart rate of patients were smaller than those of normal subjects. Sympathetic tone of patients was higher than that in normal subjects. All of these results support that autonomic disorder and cardiovascular disturbance accompanied by brain lesion could be assessed by the power spectral analysis and fractal analysis of HRV.

• Korean Journal of Oriental Medicine
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• v.16 no.1
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• pp.157-171
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• 2010

This study aimed to investigate the effect of four common types of Qigong position (standing, sitting, supine, and horse-riding position) on the autonomic nervous system. Thirty healthy subjects participated in this study once a week for four weeks. Electroencephalogram (EEG) was measured three times (before, during, and after the position) while the subject maintained one of four positions for ten minutes. There were significant changes in HRV components compared with EEG power spectra in the standing position. Especially, the ratio of low-to-high frequency (LF/HF) which represents a state of balance of autonomic nervous system was increased. In the sitting position, $\beta$ wave which reflects a state of alert consciousness was increased and both the sympathetic and parasympathetic nerves were activated. On the other hand, in the spine position, $\theta$ wave which signifies a state of relaxation was increased and heart rate (HR) was decreased. Activation of sympathetic and parasympathetic nerves was also observed in this position. Significant increases of indices related to awakening and concentration were observed accompanied by increase of HR and a sympathetic nerve was activated in the riding-horse position. In the present study, it was shown that each Qigong position caused various and significant changes in autonomic nervous system. It would be expected that these results can be applied in the choice of appropriate Qigong position according to objective of Qigong therapy although it is remained to further evaluate the effects of long-term maintenance of Qigong positions and repeated Qigong training.

• The Journal of Internal Korean Medicine
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• v.37 no.2
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• pp.361-367
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• 2016

Objective: This clinical study reports on the effect of traditional Korean medicine on a patient with generalized anxiety disorder.Method: A patient who suffered from generalized anxiety disorder was treated with herbal medicine (Guibiondamtang-gami), acupuncture, moxibustion, and pharmacopuncture. We assessed the changes of anxiety-related symptoms with the state-trait anxiety inventory (STAI) score, the Beck anxiety inventory (BAI) score, a heart rate variability (HRV) test, and a second derivative of photoplethymogram waveform (SDPTG) test.Results: After taking Guibiondamtang-gami for 22 days, the patient’s STAI score, BAI score, and LF/HF (low-frequency/high-frequency heart rate variability) ratio decreased, while the differential pulse wave index and stress power in the SDPTG test increased.Conclusion: This clinical case study has demonstrated that traditional Korean medicine may be an effective option for treating generalized anxiety disorder.

• Journal of Oriental Neuropsychiatry
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• v.22 no.4
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• pp.87-100
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• 2011

Objectives : This study aims to evaluate the relationship between HRV indices and scores of emotional questionnaires and to find out the effective way to assess patients emotional and physical condition. Methods : We selected 144 patients who had both HRV data and BDI, STAI and STAXI scores on the chart among outpatients from July 2006 to December 2010. The relationship between the scores rated from the questionnaires and HRV indices are analyzed. And the HRV indices of patients included in the top 30 percent group and the bottom 30% group are compared. Results : 1. There were no significant correlations between HRV indices and scores of BDI, STAI and trait anger of STAXI. 2. SDNN and TP of HRV significantly decreased with higher state anger scores of STAXI. The top 30 percent group of state anger had lower SDNN, TP, LF, HF and HRV-index and higher pNN50 than the bottom 30 percent group. 3. RMSSD of HRV significantly decreased with higher anger-in scores of STAXI. The top 30 percent group of anger-in had lower RMSSD than the bottom 30 percent group. Conclusions : HRV can be used to evaluate emotional and physical changes related to state anger and inappropriate anger expression.

• Journal of Nutrition and Health
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• v.26 no.5
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• pp.566-577
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• 1993

The study was to compare the effect of dietary fatty acids on fatty acid profile in tissue and the status of tocopherol and lipid peroxidation, and superoxide dismutase and glutathione peroxidase activities at two fat levels. Male Sprague Dawley rats weighing average 350g(17 weeks) were fed either low fat(LF, 4.3% w/w, 10% kcal) or high fat(HF, 20.8%, w/w, 40% kcal)diet for 6 weeks. The fats used were beef tallow as a source of saturated fatty acid, corn oil for n-6 linoleic acid, perilla oil for n-3 $\alpha$-linolenic acid and fish oil for n-3 eiocosapentatenoic acid(EPA) and n-3 docosahexaenoic acid(DHA). Palsma tocopherol was significantly reduced by fish oil compared to beef tallow at body fat level. However, there was no significant effect on the levels of plasma MDA, RBC MDA and tocopherol, and RBC hempolysis by the type and amount of dietary fat. The peroxidizibility index of fatty acid profile in plasma and liver was increased and liver MDA level was significantly increased by fish oil when dietary fat level was increased. The activities of SOD and GSHPx tended to be increased by perilla oil and fish oil at both fat oil significantly reduced the incorpration of c20:4 and increased the incorporation of c20:5 into liver compared to corn oil. The incorporation of n-3 fatty acids into tissue by perilla oil rich in $\alpha$-linolenic acid was significantly higher tan corn oil and its effect was improved with higher amount of perilla oil in diet by high fat diet. Overall, the lipid peroxidation of tissue could be prevented by tocopherol supplementation when dietary fat level was low in diet. However, at high fat diet, tocopherol supplementation might not be enough to prevent the lipid peroxidation in tissue since the potential for lipid peroxidation was tended to be increased with higher incorporation of higher unsaturated n-3 fatty acids into tissue. Therefore, it could not be recommended to consume large amount of fish oil even with excess amount of tocopherol supplemented to the high fat diet.

• Journal of Korean Medicine for Obesity Research
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• v.12 no.2
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• pp.8-16
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• 2012

Objectives: This study is designed to report the correlation between Body Mass Index(BMI), Heart Rate Variability(HRV), stess, drinking alcohol, coffee and smoking. Methods: From 1st January 2010 to 31st December 2012, We tested on 458 patients who hospitalized in Cheong Yeon Korean Medicine Hospital for reducing their weights, then we collected the statistical analysis with the result of their HRV and the special survey. Results: This experiment was studied on total 458 patients, 27 were men and 431 were women. The average of the age of men was $28.23{\pm}4.22$ and $24.31{\pm}385$ was women. There were significant differences in BMI, Low frequency(LF), High frequency(HF), stress score, frequency of drinking alcohol, smoking and drinking coffee followed by their ages. When we looked at the correlation between obesity with smoking and drinking coffee, we can see that the BMI increased, the frequency of drinking alcohol was decreased, however there were no statistic correlation in smoking and drinking coffee with BMI. Conclusions: With the result of HRV, we can suggest the BMI and stress score are correlated each other but we need further studies about passive stress relief by taking favourite food such as drinking alcohol, smoking, drinking coffee, etc.