• Title/Summary/Keyword: LCT

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Thermic Effect of Food, Macronutrient Oxidation Rate and Satiety of Medium-chain Triglyceride (중쇄중성지방(MCT)의 식이성 발열효과, 영양소 산화율 및 포만도)

  • Son, Hee-Ryoung;Lee, Myung-Ju;Kim, Eun-Kyung
    • Korean Journal of Community Nutrition
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    • v.20 no.6
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    • pp.468-478
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    • 2015
  • Objectives: The objective of this study was to evaluate the thermic effects, the macronutrient oxidation rates and the satiety of medium-chain triglycerides (MCT). Methods: The thermic effects of two meals containing MCT or long-chain triglycerides (LCT) were compared in ten healthy men (mean age $24.4{\pm}2.9years$). Energy content of the meal was 30% of resting metabolic rate of each subject. Metabolic rate and macronutrient oxidation rate were measured before the meals and for 6 hours after the meals by indirect calorimetry. Satiety was estimated by using visual analogue scales (VAS) at 8 times (before the meal and for 6 hours after meal). Results: Total thermic effect of MCT meal (42.8 kcal, 8.0% of energy intake) was significantly higher than that (26.8 kcal, 5.1% of energy intake) of the LCT meal. Mean postprandial oxygen consumption was also significantly different between the two types of meals (MCT meal: $0.29{\pm}0.35L/min$, LCT meal: $0.28{\pm}0.27L/min$). There were no significant differences in total postprandial carbohydrate and fat oxidation rates between the two meals. However, from 30 to 120 minutes after consumption of meals, the fat oxidation rate of MCT meal was significantly higher than that of the LCT meal. Comparison of satiety values (hunger, fullness and appetite) between the two meals showed that MCT meal maintained satiety for a longer time than the LCT meal. Conclusions: This study showed the possibility that long-term substitution of MCT for LCT would produce weight loss if energy intake remained constant.

Recombinant TAT-CD137 Ligand Cytoplasmic Domain Fusion Protein Induces the Production of IL-6 and TNF-${\alpha}$ in Peritoneal Macrophages

  • Kim, Jung-D.;Lee, Eun-A.;Quang, Nguyen N.;Cho, Hong-R.;Kwon, Byung-Suk
    • IMMUNE NETWORK
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    • v.11 no.4
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    • pp.216-222
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    • 2011
  • Background: The ligand for CD137 (CD137L; also called 4-1BBL) is mainly expressed on activated APCs such as dendritic cells, B cells and macrophages. Even though CD137L functions as a trigger of the CD137 signaling pathway for T cell activation and expansion, engagement of CD137L can deliver a signal leading to the production of proinflammatory cytokines in macrophages. Methods: We generated cell-permeable TAT-CD137L cytoplasmic domain fusion protein (TAT-CD137Lct) and examined its ability to initiate the CD137L reverse signaling pathway. Results: Treatment of TAT-CD137Lct induced the production of high levels of IL-6 and TNF-${\alpha}$ mRNAs and proteins in peritoneal macrophages. TAT-CD137Lct increased phosphorylation of Erk, p38 MAPK and Jnk, and activated transcription factors C/EBP and CREB. However, TAT-CD137Lct did not visibly affect the degradation of the inhibitor of NF-${\kappa}B$ ($IkB{\alpha}$). We further demonstrated that JNK activation was required for TAT-CD137Lct-induced production of TNF-${\alpha}$, while activation of Erk and p38 MAPK were involved in IL-6 and TNF-${\alpha}$ production. Conclusion: Our results suggest that TATCD137Lct is an effective activator for the CD137L reverse signaling pathway.

Performance Trial-Test of the Full-Scale Driving Pump for the Large Cavitation Tunnel(LCT) (대형캐비테이션터널(LCT) 실물 구동펌프 성능시운전)

  • Ahn, Jong-Woo;Kim, Gun-Do;Kim, Ki-Sup;Park, Young-Ha
    • Journal of the Society of Naval Architects of Korea
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    • v.52 no.6
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    • pp.428-434
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    • 2015
  • The objective of the present study is to analyze the results of the trial-test for the full-scale driving pump, which is arranged in the LCT (Large Cavitation Tunnel). Firstly, the reasons of selecting the final design pump are introduced in terms of the performance analysis in model tests. The trial-test items for the full-scale driving pump are measurements of output current/voltage at the inverter of the main motor and the flow velocity in the LCT test section. The test results show the increase in flow rate of about 10.7% and the decrease in pump head of about 26%, compared with those of final design-pump specification. The motor power has the margin of about 22%. The performance analysis for the full-scale pump is conducted using the commercial code (CFX-10). The delivered power calculated with CFX-10 shows good agreement with that extracted from the full-scale pump test. It is found that CFX-10 is useful to analyze a full-scale pump.

Experimental Study of the Interaction Characteristics for a Marine CRP in LCT (LCT에서 선박용 상호반전 프로펠러 상호작용 특성의 시험적 연구)

  • Ahn, Jong-Woo;Kim, Ki-Sup;Park, Young-Ha;Lee, Chang-Hun
    • Journal of the Society of Naval Architects of Korea
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    • v.54 no.2
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    • pp.125-131
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    • 2017
  • In order to develop test and performance analysis techniques for a CRP propulsion, a CRP dynamometer which can be installed inside the model ship was designed and manufactured. The object ship was the 16000TEU container carrier, which has test results for the single propeller. The design concept of the present CRP is that forward & after propellers have the same power ratio and their RPM ratio is 0.75:1. To begin with, we checked the performance of the CRP dynamometer through the calibration and then installed it inside the model ship. After the model ship setup including the design CRP and the rudder in the Large Cavitation Tunnel(LCT), a series of model tests composed of power ratio check, propeller behind wake(PBW) test, cavitation observation and pressure fluctuation tests was conducted. Through the model test and data analysis for CRP, the experimental technique was established and the improved method for CRP design was suggested.

Comparative Study of Full-Scale Propeller Cavitation Test and LCT Model Test for MR Tanker (MR Tanker 실선 프로펠러 캐비테이션 시험 및 LCT 모형시험과 비교연구)

  • Ahn, Jong-Woo;Paik, Bu-Geun;Seol, Han-Shin;Park, Young-Ha;Kim, Gun-Do;Kim, Ki-Sup;Jung, Bo-Jun;Choi, Sung-Jun
    • Journal of the Society of Naval Architects of Korea
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    • v.53 no.3
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    • pp.171-179
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    • 2016
  • In order to study correlation of the propeller cavitation performance between a full-scale ship and a model ship for the MR Tanker, the full-scale ship and the model tests were conducted. The full-scale ship test is composed of cavitation observation, pressure fluctuation and noise measurements, which are conducted using 2 observation windows and 8 pressure transducers installed inside the full-scale ship above the propeller. The model test in the Large Cavitation Tunnel(LCT) was conducted at the same conditions as that of the full-scale ship and its results are compared with those of the full-scale ship. Through the model-ship correlation analysis, it is considered that the experimental technique for the MR Tanker class ship was verified in LCT.

Numerical Analysis of the Wake of a Surface Ship Model Mounted in KRISO Large Cavitation Tunnel (KRISO 대형 캐비테이션터널 시험조건의 함정 모형선 반류에 대한 수치해석적 연구)

  • Park, Il-Ryong;Kim, Je-In;Kim, Ki-Sup;Ahn, Jong-Woo;Park, Young-Ha;Kim, Myoung-Soo
    • Journal of the Society of Naval Architects of Korea
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    • v.53 no.6
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    • pp.494-502
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    • 2016
  • The accurate assessment of hull-appendage interaction in the early design stage is important to control the inflow to the propeller plane, which can cause undesirable hydrodynamic effects in terms of cavitation phenomenon. This paper describes a numerical analysis for the flow around a fully appended surface ship model for which KRISO has carried out a model test in the Large Cavitation Tunnel(LCT). This numerical study was performed with the LCT model test in a complementary manner for a good reproduction of the wake distribution of surface ships. A second order accurate finite volume method provided by a commercial computational fluid dynamics(CFD) program was used to solve the governing Reynolds Averaged Navier-Stokes(RANS) equations, where the SST $k-{\omega}$ model was used for turbulence closure. The numerical results were compared to available LCT experimental data for validation. The calculations gave good predictions for the boundary layer profiles on the walls of the empty cavitation tunnel and the wake at the propeller plane of the fully appended hull model in the LCT.

Experimental Study of the POW Characteristics using High-capacity Inclined-shaft Dynamometer (고용량 경사류용 동력계를 이용한 프로펠러 단독시험 특성의 실험적 연구)

  • Ahn, Jong-Woo;Kim, Ki-Sup;Park, Young-Ha
    • Journal of the Society of Naval Architects of Korea
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    • v.56 no.2
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    • pp.168-174
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    • 2019
  • In order to investigate Propeller Open Water (POW) characteristics for the high-speed propeller in Large Cavitation Tunnel (LCT), the high-capacity inclined-shaft dynamometer was designed and manufactured. Its measuring capacities of thrust and torque are ${\pm}2200N$ and ${\pm}120N-m$, respectively. The driving motor is directly connected to the propeller shaft. Inclined angle of the propeller shaft can be adjusted up to ${\pm}10^{\circ}$. As the pressure inside LCT can be adjusted in the range of 0.1~3.0bar, we can carry out the POW test at high Reynolds number (above $1.0{\times}10^6$) without propeller cavitation and the cavitation test in uniform flow. After the new dynamometer setup in LCT, the Reynolds number variation test and propeller open-water test were conducted at the inclined angle of $0^{\circ}$ and $6^{\circ}$. The present POW results of the new dynamometer are compared with those of the existing high-capacity dynamometer in LCT and of the dynamometer in the towing-tank. Through systematic model tests and comparison with their results, the performance of the new inclined-shaft dynamometer was verified. It is thought the POW test for the high-speed propeller should be better conducted at high Reynolds number.

Performance Improvement Study of Propeller Propulsion Efficiency and Cavitation for the 8800TEU Class Container (8800TEU급 컨테이너선 프로펠러 추진효율 및 캐비테이션 성능향상 연구)

  • Ahn, Jong-Woo;Kim, Gun-Do;Kim, Ki-Sup;Park, Young-Ha;Ahn, Hae-Seong;Jung, Young-Jun;Yoon, Ji-Hyun
    • Journal of the Society of Naval Architects of Korea
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    • v.54 no.6
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    • pp.453-460
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    • 2017
  • In order to investigate propulsion efficiency and cavitation characteristics for expanded area ratio variation of the 8800TEU class container propeller, a series of performance tests were conducted at Large Cavitation Tunnel (LCT) and Towing Tank (TT) in KRISO. The cavitation test of the existing propellers (KP1029 & KP1030) was conducted using FRP model ship in LCT. On the basis of LCT test results, it was required to design propeller with better propulsion efficiency and cavitation performance. Two propellers (KP1171 & KP1172) with decreased expanded area ratio were designed on the basis of KP1029 propeller. The new design propellers showed higher efficiency than KP1029 and reasonable cavitation performance. In the future, they will be applied as the standard propeller for the propeller design of the large container ship. Through the performance test and prediction results for the new design propellers, it is thought that high-load propeller with better propulsion efficiency and cavitation performance will be developed constantly.

Synthesis and Characterization of Wholly Aromatic Polyester Liquid Crystalline Thermosets (전방향족 폴리에스터 열경화성 액정의 합성과 특성)

  • Moon, Hyun-Gon;Jung, Myung-Sup;Chang, Jin-Hae
    • Polymer(Korea)
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    • v.36 no.1
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    • pp.9-15
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    • 2012
  • We prepared a series of aromatic liquid crystals (LCs) based on wholly aromatic ester units with the reactive end group methyl maleimide by means of melt condensation method, and the resulting LCs were thermally crosslinked to produce liquid crystalline thermoset (LCT) films. The synthesized LCs and LCTs were characterized with Fourier transform infrared (FTIR) spectroscopy, wide angle X-ray diffraction (WAXD), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), thermomechanical analysis (TMA), and polarizing optical microscopy (POM) with a hot stage. The glass transition temperature ($T_g$) and coefficient of thermal expansion are strongly affected by the mesogen units in their main chain structures. The $p$-substituted biphenyl LC was found to have the highest thermal property value.

Liquid Crystalline Thermoset Films Based on Wholly Aromatic Copolymers (전방향족 공중합체의 열경화성 액정필름)

  • Moon, Hyun-Gon;Ahn, Yong-Ho;Chang, Jin-Hae
    • Polymer(Korea)
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    • v.34 no.4
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    • pp.369-375
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    • 2010
  • We used melt polymerization method to prepare a series of aromatic liquid crystals (LCs) based on aromatic ester and amide units with the reactive methyl-maleimide end group, and then the resulting thermally cross-linked LCs to produce LC thermoset films by means of solution casting and the followed heat treatment. The synthesized LCs and LCTs were characterized by Fourier transform infrared (FTIR) spectroscopy, differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), thermomechanical analysis (TMA), X-ray diffractometry (XRD), and polarizing optical microscopy (POM) with a hot stage. All of the LCs prepared by melt polymerization method formed smectic mesophases. The thermal properties of the LC and LCT films were strongly affected by the mesogen units in the main chain structures. The thermal expansion coefficients of samples were in the range of 27.72~50.95 ppm/$^{\circ}C$.