Recombinant TAT-CD137 Ligand Cytoplasmic Domain Fusion Protein Induces the Production of IL-6 and TNF- in Peritoneal Macrophages |
Kim, Jung-D.
(School of Biological Sciences, Ulsan University Hospital, University of Ulsan School of Medicine)
Lee, Eun-A. (School of Biological Sciences, Ulsan University Hospital, University of Ulsan School of Medicine) Quang, Nguyen N. (School of Biological Sciences, Ulsan University Hospital, University of Ulsan School of Medicine) Cho, Hong-R. (Department of Surgery, Ulsan University Hospital and School of Medicine) Kwon, Byung-Suk (School of Biological Sciences, Ulsan University Hospital, University of Ulsan School of Medicine) |
1 | Laderach D, Wesa A, Galy A: 4-1BB-ligand is regulated on human dendritic cells and induces the production of IL-12. Cell Immunol 226:37-44, 2003. DOI ScienceOn |
2 | Lippert U, Zachmann K, Ferrari DM, Schwarz H, Brunner E, Mahbub-Ul Latif AH, Neumann C, Soruri A: CD137 ligand reverse signaling has multiple functions in human dendritic cells during an adaptive immune response. Eur J Immunol 38:1024-32, 2008. DOI ScienceOn |
3 | Schwarz H, Blanco FJ, von Kempis J, Valbracht J, Lotz M: ILA, a member of the human nerve growth factor/tumor necrosis factor receptor family, regulates T-lymphocyte proliferation and survival. Blood 87:2839-45, 1996. |
4 | Kwajah M M S, Mustafa N, Holme AL, Pervaiz S, Schwarz H: Biphasic activity of CD137 ligand-stimulated monocytes on T cell apoptosis and proliferation. J Leukoc Biol 89:707-20, 2011. DOI ScienceOn |
5 | Pauly S, Broll K, Wittmann M, Giegerich G, Schwarz H: CD137 is expressed by follicular dendritic cells and costimulates B lymphocyte activation in germinal centers. J Leukoc Biol 72:35-42, 2002. |
6 | Pollok KE, Kim YJ, Hurtado J, Zhou Z, Kim KK, Kwon BS: 4-1BB T-cell antigen binds to mature B cells and macrophages, and costimulates anti-mu-primed splenic B cells. Eur J Immunol 24:367-74, 1994. DOI ScienceOn |
7 | Jeon HJ, Choi JH, Jung IH, Park JG, Lee MR, Lee MN, Kim B, Yoo JY, Jeong SJ, Kim DY, Park JE, Park HY, Kwack K, Choi BK, Kwon BS, Oh GT: CD137 (4-1BB) deficiency reduces atherosclerosis in hyperlipidemic mice. Circulation 121:1124-33, 2010. DOI ScienceOn |
8 | Salih HR, Kosowski SG, Haluska VF, Starling GC, Loo DT, Lee F, Aruffo AA, Trail PA, Kiener PA: Constitutive expression of functional 4-1BB (CD137) ligand on carcinoma cells. J Immunol 165:2903-10, 2000. DOI |
9 | Gullo C, Koh LK, Pang WL, Ho KT, Tan SH, Schwarz H: Inhibition of proliferation and induction of apoptosis in multiple myeloma cell lines by CD137 ligand signaling. PLoS One 5:e10845, 2010. DOI |
10 | Drenkard D, Becke FM, Langstein J, Spruss T, Kunz-Schughart LA, Tan TE, Lim YC, Schwarz H: CD137 is expressed on blood vessel walls at sites of inflammation and enhances monocyte migratory activity. FASEB J 21:456-63, 2007. DOI ScienceOn |
11 | Eissner G, Kolch W, Scheurich P: Ligands working as receptors: reverse signaling by members of the TNF superfamily enhance the plasticity of the immune system. Cytokine Growth Factor Rev 15:353-66, 2004. DOI ScienceOn |
12 | Schwarz H: Biological activities of reverse signal transduction through CD137 ligand. J Leukoc Biol 77:281-6, 2005. DOI |
13 | Shao Z, Schwarz H: CD137 ligand, a member of the tumor necrosis factor family, regulates immune responses via reverse signal transduction. J Leukoc Biol 89:21-9, 2011. DOI ScienceOn |
14 | Langstein J, Michel J, Fritsche J, Kreutz M, Andreesen R, Schwarz H: CD137 (ILA/4-1BB), a member of the TNF receptor family, induces monocyte activation via bidirectional signaling. J Immunol 160:2488-94, 1998. |
15 | Langstein J, Michel J, Schwarz H: CD137 induces proliferation and endomitosis in monocytes. Blood 94:3161-8, 1999. |
16 | Langstein J, Schwarz H: Identification of CD137 as a potent monocyte survival factor. J Leukoc Biol 65:829-33, 1999. DOI |
17 | Langstein J, Becke FM, Sollner L, Krause G, Brockhoff G, Kreutz M, Andreesen R, Schwarz H: Comparative analysis of CD137 and LPS effects on monocyte activation, survival, and proliferation. Biochem Biophys Res Commun 273:117-22, 2000. DOI ScienceOn |
18 | Ju SW, Ju SG, Wang FM, Gu ZJ, Qiu YH, Yu GH, Ma HB, Zhang XG: A functional anti-human 4-1BB ligand monoclonal antibody that enhances proliferation of monocytes by reverse signaling of 4-1BBL. Hybrid Hybridomics 22:333-8, 2003. DOI ScienceOn |
19 | Kang YJ, Kim SO, Shimada S, Otsuka M, Seit-Nebi A, Kwon BS, Watts TH, Han J: Cell surface 4-1BBL mediates sequential signaling pathways 'downstream' of TLR and is required for sustained TNF production in macrophages. Nat Immunol 8:601-9, 2007. |
20 | Lee SW, Park Y, So T, Kwon BS, Cheroutre H, Mittler RS, Croft M: Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells. Nat Immunol 9:917-26, 2008. |
21 | Jiang D, Chen Y, Schwarz H: CD137 induces proliferation of murine hematopoietic progenitor cells and differentiation to macrophages. J Immunol 181:3923-32, 2008. |
22 | Jiang D, Yue PS, Drenkard D, Schwarz H: Induction of proliferation and monocytic differentiation of human CD34+ cells by CD137 ligand signaling. Stem Cells 26:2372-81, 2008. DOI ScienceOn |
23 | Asoh S, Ohta S: PTD-mediated delivery of anti-cell death proteins/peptides and therapeutic enzymes. Adv Drug Deliv Rev 60:499-516, 2008. DOI ScienceOn |
24 | Choi JM, Ahn MH, Chae WJ, Jung YG, Park JC, Song HM, Kim YE, Shin JA, Park CS, Park JW, Park TK, Lee JH, Seo BF, Kim KD, Kim ES, Lee DH, Lee SK, Lee SK: Intranasal delivery of the cytoplasmic domain of CTLA-4 using a novel protein transduction domain prevents allergic inflammation. Nat Med 12:574-9, 2006. DOI ScienceOn |
25 | Choi JM, Kim SH, Shin JH, Gibson T, Yoon BS, Lee DH, Lee SK, Bothwell AL, Lim JS, Lee SK: Transduction of the cytoplasmic domain of CTLA-4 inhibits TcR-specific activation signals and prevents collagen-induced arthritis. Proc Natl Acad Sci U S A 105:19875-80, 2008. DOI ScienceOn |
26 | Kwon B: CD137-CD137 Ligand Interactions in Inflammation. Immune Netw 9:84-9, 2009. DOI |