• Title/Summary/Keyword: LC20

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Evaluation of the Changes in Polymerization of TheraCal LC with Various Light-curing Time and Distance (광중합 시간과 거리의 변화에 따른 TheraCal LC의 중합도 평가)

  • Bae, Sangyong;Lee, Jewoo;Ra, Jiyoung
    • Journal of the korean academy of Pediatric Dentistry
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    • v.46 no.4
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    • pp.392-399
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    • 2019
  • The purpose of this study was to evaluate polymerization of TheraCal LC, one of the tricalcium silicate cements. To measure the Vickers hardness number (VHN), the specimens were cured at different light curing time and distance. As a result, the VHN of the upper surface was significantly higher than the lower surface's in all groups (p < 0.05). The VHN of the lower surface was increased significantly with the increase of the light curing time in all distance (p < 0.05). When the distance was more than 4.0 mm at all light curing time, the VHN of lower surface was significantly decreased (p < 0.05). When the specimen was light cured for 20 seconds, the VHN of the lower surface did not exceed 2, which corresponds to 10% of the upper surface's. These results suggested that the 20 second light curing time was not sufficient to polymerize the lower surface under specific conditions and that light-curing time should be increased.

Gene Regulations in HBV-Related Liver Cirrhosis Closely Correlate with Disease Severity

  • Lee, Se-Ram;Kim, So-Youn
    • BMB Reports
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    • v.40 no.5
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    • pp.814-824
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    • 2007
  • Liver cirrhosis (LC) is defined as comprising diffuse fibrosis and regenerating nodules of the liver. The biochemical and anatomical dysfunction in LC results from both reduced liver cell number and portal vascular derangement. Although several studies have investigated dysregulated genes in cirrhotic nodules, little is known about the genes implicated in the pathophysiologic change of LC or about their relationship with the degree of decompensation. Here, we applied cDNA microarray analysis using 38 HBsAg-positive LC specimens to identify the genes dysregulated in HBV-associated LC and to evaluate their relation to disease severity. Among 1063 known cancer- and apoptosis-related genes, we identified 104 genes that were significantly up- (44) or down- (60) regulated in LC. Interestingly, this subset of 104 genes was characteristically correlated with the degree of decompensation, called the Pugh-Child classification (20 Pugh-Child A, 10 Pugh-Child B, and 8 Pugh-Child C). Patient samples from Pugh-Child C exhibited a distinct pattern of gene expression relative to those of Pugh-Child A and B. Especially in Pugh-Child C, genes encoding hepatic proteins and metabolizing enzymes were significantly down-regulated, while genes encoding various molecules related to cell replication were up-regulated. Our results suggest that subsets of genes in liver cells correspond to the pathophysiologic change of LC according to disease severity and possibly to hepatocarcinogenesis.

The improvement of GTG response time using new concept LC mixture in S-IPS Mode for high frame frequency technologies

  • Kim, D.K.;Lim, C.S.;Lee, D.J.;Hwang, J.I.;Jung, H.G.;Lee, S.W.;Oh, C.H.;Kang, I.B.;Jin, Min-Ok;Jin, Heui-Seok;Lee, Seung-Eun;Jacob, Thomas;Czanta, Markus;Tarumi, Kazuaki
    • 한국정보디스플레이학회:학술대회논문집
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    • 2006.08a
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    • pp.864-867
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    • 2006
  • In order to satisfy with the clear visibility without any difficulties such as blurring and tailing, the high refreshing rate technology and fast response time of LC itself were applied to TFT-LCDs. In proportion to the decrease of holding time of 1 frame, the fast transition of LC behavior was necessary to both maintain the luminance and minimize the tailing appearance. The introduction of a new LC mixture for faster response times was realized by the good combination of newly introduced dielectrically neutral LC material so called 'Super Low Viscosity' (SLV) and highly polar $CF_2O-linkage$ LC material. This resulted in about a 20% reduction in the ${\gamma}_1$ of the new LC mixture compared to the references. In accordance with a new LC mixture with low ${\gamma}_1$, fast response time of 5ms has been made for S-IPS LCD TV application. Consequently, by applying the high frame frequency of 120Hz driving alongside the 5ms response time characteristics, the MPRT value was reduced by half.

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Effects of Suspended Solid and Cadmium on the Shallow-sea Ecosystem II. Acute and Chronic Toxicity of Cadmium to a Herbivorous Copepod, Tigriopus japonicus (천해역 먹이망 생태계에 대한 무기부유입자와 카드뮴의 영향 II. Tigriopus japonicus에 대한 카드뮴의 급성 및 만성독성)

  • CHUNG Ee-Yung;SHIN Yun Kyung;YIH Wonho
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.29 no.1
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    • pp.124-133
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    • 1996
  • A herbivorous copepod, Tigriopus japonicus, was tested to study its acute and chronic responses to Cd tonicity. Under $20^{\circ}C,\;96hr-LC_{50}$ of T. japonicus in medium with $32\%_{\circ},\;26\%_{\circ},\;and\;18\%_{\circ}$ salinity were 11.1 ppm, 13.7 ppm, and 9.7 ppm, respectively. The $96hr-LC_{50}$ in medium with $32\%_{\circ},\;26\%_{\circ},\;and\;18\%_{\circ}$ salinity increased to 21.6 ppm, 15.0 ppm, and 11,0 ppm, respectively under $10^{\circ}C$ condition. Oxygen consumption rates during 96hrs exposure to Cd toxicity decreased more sharply at $20^{\circ}C$ than those at $10^{\circ}C$. Survival rate and $250dys-LC_{50}$ of T. japonicus in medium with $32\%_{\circ}$ salinity, in concentration of Cd 4 ppm were $5\%$ and 0.05 ppm, respectively under $10^{\circ}C$, and $0\%$ and 0.20 ppm under $20^{\circ}C$. It was that the copepod selectively feed on Skeletonema costatum, Nitzschia pungens, N. seriata, and Rhizosolenia hebetata f. semispina.

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Determination of perchlorate in the Gum-River surface water by LC-ESI-MS/MS (금강 지표수에서 LC-ESI-MS/MS에 의한 염소산이온의 극미량 분석)

  • Lee, Young Joon;Lee, Jun Bae;Hong, Seon Haw;Kim, Hyun-Ji;Shin, Ho-Sang
    • Analytical Science and Technology
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    • v.25 no.6
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    • pp.435-440
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    • 2012
  • A liquid chromatography-electrospray ionization-tandem mass spectrometry method (LC-ESI-MS/MS) was used for determining perchlorate in the Gum-River surface water. Sample was directly injected into LC-ESI-MS/MS after the filtrations using PTFE filter paper. The coefficient of variation of perchlorate was less than 3% and the limit of quantification was 0.17 ${\mu}g/L$. Water samples were collected from thirty-five basins of Gum-River on February, April and June 2012, respectively. As a result, perchlorate was detected in the concentration range of 0.23-3.73 ${\mu}g/L$ (mean 0.20 ${\mu}g/L$) in the frequency of 15% in general surface water and in the concentration range of 0.36-25.10 ${\mu}g/L$ (mean 1.69 ${\mu}g/L$) in the frequency of 36% in surface water samples near industry area.

Development of Multi-residue Analytical Method for 261 Pesticides in Herbal Medicines using GC-MS/MS and LC-MS/MS (GC-MS/MS와 LC-MS/MS를 이용한 생약재 중 261종 농약의 동시분석)

  • Na, Eun Shik;Kim, Seong Soo;Hong, Sung Soo;Kim, Kyoung Ju;Lee, Yong Jae;Lee, Byung Chul;Lee, Kyu Seung
    • Korean Journal of Environmental Agriculture
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    • v.39 no.2
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    • pp.142-169
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    • 2020
  • BACKGROUND: A new analytical method has been developed to determine 261 pesticide residues in herbal medicines. METHODS AND RESULTS: The extraction of pesticides was carried out by modified method of the Korea Food Standards Codex sample extraction and determination was performed using GC-MS/MS and LC-MS/MS. During the pre-treatment process of the test method, Solid-liquid separation was changed to centrifugation. The method was validated by the precision and accuracy results. 261 pesticides spiked at three level 20, 50, 100 ug/kg in herbal medicines. The limit of quantification of method were 4-40 ug/kg for GC-MS/MS and 2-45 ug/kg for LC-MS/MS, respectively. Among the pesticides analysed by GC-MS/MS and LC-MS/MS, 244 pesticides (94% of total number) in chinese matrimony vine and 224 pesticides (86% of total number) in korean angelica root and 231 pesticides (89% of total number) in jujube and 214 (82% of total number) in cnidium showed recoveries in the range of 70-120% with RSD⪯20%. CONCLUSION: These results indicated that GC-MS/MS and LC-MS/MS analysis with the sample extraction in this study can be applied to multi-residue analysis of pesticides in herbal medicines.

Alignment Effect of a Nematic Liquid Crystal on Deposited SiOx Thin-Film Surface with e-beam Evaporation

  • Oh, Yong-Cheul;Lee, Dong-Gyu
    • Transactions on Electrical and Electronic Materials
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    • v.7 no.6
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    • pp.305-308
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    • 2006
  • We have studied liquid crystal (LC) aligning capabilities for homeotropic alignment and the control of tilt angles on the $SiO_{x}$ thin film by electron beam evaporation method. A high tilt angle of about $86.5^{\circ}$ was obtained, and also the suitable tilt angle of the NLC on the $SiO_{x}$ thin film at $20{\sim}50\;nm$ thickness with e-beam evaporation can be achieved. The uniform LC alignment on the $SiO_{x}$ thin film surfaces with electron beam evaporation can be achieved. It is considerated that the LC alignment on the $SiO_{x}$ thin film by electron beam evaporation is attributed to elastic interaction between LC molecules and micro-grooves at the $SiO_{x}$ thin film surface created by evaporation.

The Effects of Green Tea on the Serum Lipid and Liver Tissue of Cholesterol Fed Rats (녹차의 음용이 지방과 콜레스테롤을 투여한 흰쥐의 혈청지질 및 간의 조직에 미치는 영향)

  • Sin, Mee-Kung;Han, Sung-Hee;Han, Gun-Jo
    • Korean Journal of Food Science and Technology
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    • v.29 no.6
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    • pp.1255-1263
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    • 1997
  • This study was performed to investigate the effects of green tea on fat metabolism of rats and prevention to cardiovascular disease in drinking green tea. Male Spague-Dawley rats were divided into seven groups consisting of the control, lard and cholestrol, aqueous green tea at the level of 1% and 3%. After 4 weeks of feeding serum lipid levels were measured for experimental rats, and analyzed the total cholesterol (TC), HDL-cholesterol (HDL-C), triglyceride (TG), phospholipid (PL). And total lipid (TL) to Folch method, lipid deposition to oil red O staining on liver tissue. The results are as follows: Total cholesterol (TC) decreased by administration of 1% aqueous green tea group and increased addition to lard and cholesterol (LC) group as compared to each groups (p<0.05). HDL-cholestrol in serum increased by administration of la aqueous green tea group (1G) and decreased to the control group, 1% aqueous green tea (L-1G) added lard group (p<0.05). Triglyceride (TG) decreased by administration of 3% aqueous green tea groups (L-3G, LC-3G) and increased by lard and cholesterol group (LC) (p<0.01). Phospholipid(PL) decreased by administration of 3% aqueous green tea added lard and cholesterol group (LC-3G) and increased by control group, lard and cholestrol group (LC) (p<0.05). Total lipid of liver decreased by administration of aqueous green tea at the level of 1% group and increased by LC group (p<0.01). The fat deposition of liver was increased in fat diet groups and decrease in the drink green tea of some but did not showed significant differences from concentration of the green tea.

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Quantitative Analysis of the Twenty Marker Components in Gwakhyangjeonggi-san using Ultra-Performance Liquid Chromatography with Mass Spectrometer (LC-MS/MS를 이용한 곽향정기산(藿香正氣散) 추출물 중 20종 성분의 함량분석)

  • Seo, Chang-Seob;Shin, Hyeun-Kyoo
    • Korean Journal of Pharmacognosy
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    • v.45 no.2
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    • pp.113-120
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    • 2014
  • Generally, Gwakhyangjeonggi-san has been used for treatment of diarrhea-predominant irritable bowel syndrome. In this study, an ultra-performance liquid chromatography-electrospray ionization-mass spectrometer method was established for the simultaneous quantification of marker compounds 1-20 in Gwakhyangjeonggi-san water extract. All analytes were separated by gradient elution using two mobile phases on a UPLC BEH $C_{18}$ ($100{\times}2.1mm$, $1.7{\mu}m$) column and maintained at $45^{\circ}C$. The injection volume was $2.0{\mu}L$ and the flow rate was 0.3 mL/min with detection at mass spectrometer. Regression equations of the compounds 1-20 were acquired with $r^2$ values ${\geq}0.9950$. The values of limit of detection and quantification of all analytes were 0.01-2.79 ng/mL and 0.03-8.37 ng/mL, respectively. The amounts of the compounds 1-20 in Gwakhyangjeonggi-san water extract were not detected $-3,236.67{\mu}g/g$. The established LC-MS/MS methods will be valuable to improve quality control of traditional herbal formula, Gwakhyangjeonggi-san.

A New LC Resonator Fabricated by MEMS Technique and its Application to Magnetic Sensor Device (MEMS 공정에 의한 LC-공진기형 자기센서의 제작과 응용)

  • Kim, Bong-Soo;Kim, Yong-Seok;Hwang, Myung-Joo;Lee, Hee-Bok
    • Journal of the Korean Magnetics Society
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    • v.17 no.3
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    • pp.141-146
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    • 2007
  • A new class of LC-resonator for micro magnetic sensor device was invented and fabricated by means of MEMS technique. The micro LC-resonator consists of a solenoidal micro-inductor with a bundle of soft magnetic microwire cores and a capacitor connected in parallel to the micro-inductor. The core magnetic material is a tiny glass coated $Co_{83.2}B_{3.3}Si_{5.9}Mn_{7.6}$ microwire fabricated by a glasscoated melt spinning technique. The core materials were annealed at various temperatures $150^{\circ}C,\;200^{\circ}C\;,250^{\circ}C\;,$ and $300^{\circ}C$ for 1 hour in a vacuum to improve soft magnetic properties. The solenoidal micro-inductors fabricated by MEMS technique were $500{\sim}1,000{\mu}m$ in length with $10{\sim}20$ turns. The changes of inductance as a function of external magnetic field in micro-inductors with properly annealed microwire cores were varied as much as 370%. Since the permeability of ultra soft magnetic microwire is changing rapidly as a function of external magnetic field. The inductance ratio as well as magnetoimpedance ratio (MIR) in a LC-resonator was varied drastically as a function of external magnetic field. The MIR curves can be tuned very precisely to obtain maximum sensitivity. A prototype magnetic sensor device consisting of the developed microinductors with a multivibrator circuit was test successfully.